(1668,'10.1080/10412905.2015.1093556','Antiviral activity of Colombian Labiatae and Verbenaceae family essential oils and monoterpenes on Human Herpes viruses','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1093556',62,'https://openalex.org/W2169139342','Colombian flora includes plant families such as Labiatae and Verbenaceae which are employed for treatment of several diseases. In this study, the chemical compositions of essential oils belonging to Labiatae and Verbenaceae families were determined by GC-MS and GC-FID, respectively. The antiviral activity of forty essential oils of these plants and some monoterpenes were evaluated on Human Herpes Viruses types 1 and 2 using end-point titration technique (EPTT). Furthermore, the essential oils and monoterpenes with higher activity reported in the screening were used to evaluate the inhibitory effect on pre-infective stages. The essential oils with the most anti-herpetic activity were those of Labiatae family with Rf values of 1 Ã 102 and 1 Ã 103 against one Tissue Culture Infectious Dose 50 (TCID50) of HHV-1 and HHV-2. Moreover Lepechinia salvifolia, Hyptis mutabilis, Lepechinia vulcanicola, Mintostachys mollis and Ocimum campechianum essential oils showed inhibitory activity in the early stages of infection.'),(1669,'10.1080/10412905.2015.1093969','Chemical composition and evaluation of the essential oil from<i>Eupatorium glabratum</i>as biopesticide against<i>Sitophilus zeamais</i>and several stored maize fungi','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1093969',14,'https://openalex.org/W2253826681','Essential oil (EO) from the weedy shrub Eupatorium glabratum was analyzed by gas chromatography/mass spectrometry and then evaluated as insecticide and repellent against Sitophilus zeamais and as fungicide against Fusarium commune, F. graminaearum, F. sporotrichum, Penicillium expansum, and Phoma herbarum. The EO was composed mainly by monoterpenes, with α-pinene (29.5%) and α-phellandrene (19.6%) as the most abundant. S. zeamais showed similar susceptibility to pure vapors of α-pinene and α-phellandrene, and to whole EO of Eupatorium glabratum. The EO killed insects exposed to its vapors for 1 week (LC50=18.0 μLmLâ1 air). The LC50 for daily female insect mortality was 16.0 μL-mLâ1 air, and for males 20 μL-mLâ1 air). The EO was repellent in olfactometry tests for females and males at 0.4 μL oil cm-2, but attractive for males at 0.1 μLoil cm-2. The EO also was differentially antagonistic to fungi, inhibiting at various degrees spore germination, germinal tube elongation and mycelium growth.'),(1670,'10.1080/10412905.2015.1099119','Influence of light intensity on glandular trichome density, gene expression and essential oil of menthol mint (<i>Mentha arvensis</i>L.)','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1099119',29,'https://openalex.org/W2239154723','The effects of 25, 50, 75 and 100% of light intensity (137, 254, 406 and 543 μmol photons mâ2 secondâ1, respectively) on aspects related to volatile synthesis in menthol mint were investigated. Fresh weight production, glandular trichome density and essential oil content showed a significant linear positive correlation with light intensity. Plants under low light intensity (25%) produced an essential oil with high levels of neomenthol, menthol and menthyl acetate. With 50 and 75% of light intensity plants showed an increase in expression of limonene synthase, limonene hydroxylase, (-)-isopiperitenol dehydrogenase, (+)-pulegone reductase and menthol dehydrogenase genes and an anticipation in oil maturity. With 25% of light intensity plants produced an essential oil with the best commercial profile. However, plants under 100% of light intensity produced more essential oil but with lower levels of menthol and higher levels of pulegone, that can be toxic for humans.'),(1671,'10.1080/10412905.2015.1107646','Identification of antibiotic and antiproliferative compounds in natural orange blossom water','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1107646',1,'https://openalex.org/W2234258290','Orange blossom water (Citrus aurantium L. ssp aurantium) is a hydrosol widely used in cosmetics, medicine and in the food industry. When exposed to sunlight for a few days, the hydrosol turns orange and a precipitate appears afterwards. Despite the economic importance of the orange blossom water, this phenomenon has never been studied and the chemical changes taking place have never been elucidated. This study reports on the comparative analysis of sunlight exposed and non-exposed hydrosols by UV-Visible spectroscopy, GC and HPLC. The formation of several indole derivatives (isatin, oxindole, indole-3-carboxaldehyde, 3,3â-diindolylmethane, turbomycin A) induced by the exposition of orange blossom water to sunlight was observed. Two of these derivatives have already been identified as biologically active compounds: 3,3â-diindolylmethane displays an antiproliferative activity against various human cancer cell lines and turbomycin A presents a broad-range antibiotic activity. The later one was identified in this study as the compound responsible for the orange coloration of sunlight-exposed orange blossom water.'),(1672,'10.1080/10412905.2015.1108880','Chemical composition, antimicrobial and antioxidant activities of the essential oil of<i>Lippia javanica</i>leaves from Ethiopia','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1108880',19,'https://openalex.org/W2303271750','The leaves of Lippia javanica are used for the treatment of several skin diseases in Ethiopia. Forty-two components were identified and quantified, by GCâMS and GCâFID, comprising 98.9% of the total oil with cis-sabinene hydrate (20.3%) and limonene (13.9%) as major components. cis-Sabinene hydrate is reported here for the first time as a constituent of L. javanica leaf oil (Ethiopia). The essential oil and its two fractions were assessed for their possible antimicrobial activities against two bacterial strains (Bacillus cereus and Klebsiella pneumoniae) and one fungal pathogen (Cryptococcus neoformans) using the disc diffusion method. K. pneumoniae was found to be the most susceptible bacteria to the oxygenated fraction (MIC < 5 ï­g/mL). The antioxidant property of the oil was assessed by free radical scavenging (DPPH) assay, with IC50 = 16.6 ï­L/mL. These findings may support the traditional uses of the plant for the treatment of skin diseases.'),(1673,'10.1080/10412905.2015.1110062','Antifungal activities after vaporization of ajowan ( <i>Trachyspermum ammi</i> ) and allspice ( <i>Pimenta dioica</i> ) essential oils and blends of their constituents against three <i>Aspergillus</i> species','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1110062',17,'https://openalex.org/W2289806526','The fumigant antifungal activities of ajowan (Trachyspermum ammi), and allspice (Pimenta dioica) essential oils and their constituents were tested against three Aspergillus species: A. ochraceus, A. parasiticus, and A. niger. Ajowan essential oil demonstrated a 100% inhibition rate against these three Aspergillus species at an air concentration of 56 Ã 10â3 mg/mL. The fumigant antifungal activities of allspice essential oil against A. niger, A. ochraceus, and A. parasiticus were 100, 84.4, and 83.5%, respectively. Gas chromatography-mass spectrometry analysis led to the identification of twelve compounds in ajowan oil and six compounds in allspice oil. Of the compounds tested, thymol, carvacrol, and eugenol showed strong inhibitory activity against the three Aspergillus species. The fumigant antifungal activities of blends of the constituents identified in ajowan and allspice oils indicated that thymol and eugenol were the major contributors to the fumigant antifungal activities of ajowan and allspice oils, respectively.'),(1674,'10.1080/10412905.2015.1113205','Sensory analysis and head-space aroma volatiles for the characterization of capers from different geographic origin','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1113205',22,'https://openalex.org/W2281743295','Characterization of capers (Capparis spinosa L. Capparaceae) was achieved by measurement of aroma compounds and sensory descriptors. Different capper samples (the floral buds of the plants) coming from Pantelleria and Salina Islands (Italy) were analyzed. Head-space aroma volatiles were extracted and analyzed by SPME-GC-MS. In all, more than one-hundred volatile compounds were identified and the quantitative results have been expressed as percentage of total peak area. Aliphatic acids and aldehydes were the most abundant chemical classes in all the samples whereas aromatic alcohols distinguish the samples from different origin. Among sulfur compounds, methyl-isothiocyanate was the major one, followed by benzyl-isothiocyanate. The sensory profile of capers was defined by a trained panel, measuring the intensity of nineteen descriptors. All the data were statistically correlated. Multivariate analysis applied to the volatile and sensory data allowed distinguishing the samples in relation to the area of origin.'),(1675,'10.1080/10412905.2015.1114532','Water-soluble essential oil components of fresh flowers of<i>Osmanthus fragrans</i>Lour','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1114532',14,'https://openalex.org/W2302986092','Water-soluble essential oil components of Osmanthus fragrans fresh flowers were recovered from the hydrolate and the cold infusion, byproducts of essential oil isolation and concrete extraction, respectively. Chemical investigation was performed by gas chromatography (GC) and gas chromatography â mass spectrometry (GC-MS). As a comparative study, the Clevenger-distilled, decanted and absolute oils were also analyzed. The oil recovered from the hydrolate was mainly composed of cis-linalool oxide (furanoid) (51.4%) and trans-linalool oxide (furanoid) (37.8%). This oil presented 0.024 ± 0.004% (w/w) relative to the fresh flowers, and accounted for 25.5 ± 5.8% of the total oil (decanted + recovered). The oil recovered from the cold infusion was rich in 4-methoxyphenethyl alcohol (31.0%), 4-hydroxyphenethyl alcohol (18.0%), cis-linalool oxide (furanoid) (9.8%), cis-linalool oxide (pyranoid) (8.9%) and trans-linalool oxide (furanoid) (7.3%). This oil accounted for 0.018 ± 0.003% (w/w) of the fresh flowers. In summary, the recovered water-soluble oils are valued for being rich in compounds characteristic of O. fragrans and can find applications in the essential oil industry.'),(1676,'10.1080/10412905.2015.1118411','Chemical and biological profiles of essential oils from<i>Mentha spicata</i>L. leaf from Bejaia in Algeria','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2015.1118411',40,'https://openalex.org/W2307326938','Air-dried leaves of Mentha spicata L. were collected in Bejaia location (Algeria) during 2013. The plant samples were distillated by Clevenger apparatus and the essential oils obtained were analyzed by GC and GC/MS. Fifty compounds amounting to 98.9% of the oil, were identified. The major components of the oil were carvone (48.5%), limonene (20.7%), and 1,8-cineole (5.4%). This oil exhibited high antimicrobial activity with a high effectiveness against Candida albicans strain with a diameter of growth inhibition zones of ranging from 14.3 ± 1.5 to 44.3 ± 1.1 mm. The antioxidant activity determined by five different test systems showed that the oil exhibits moderate activity. The insecticidal activity has been tested on the adults of Rhyzopertha dominica F., the main pest of wheat. Contact and fumigant toxicity assays showed mortality percentages of 14.0 and 34.5% respectively at the dose of 2 μL/mL and the repellency percentage was 56.2% at 30 minutes.'),(1677,'10.1080/10412905.2015.1119762','Chemical compositions and antibacterial activities of five selected aromatic plants essential oils against food-borne pathogens and spoilage bacteria','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1119762',28,'https://openalex.org/W2308475931','The aim of this work was to investigate chemical compositions and antibacterial properties of several Iranian essential oils (EO) bearing plants including Satureja hortensis, Trachyspermum ammi, Mentha piperita, Lippia citrodora, and Foeniculum vulgare. Antibacterial properties of EOs against Pseudomonas putida, Enterobacter aerogenes, Salmonella typhi and Escherichia coli as Gram-negative bacteria and also Leuconostoc mesenteroides subsp.mesenteroides, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus as Gram-positive bacteria were determined by Disk diffusion agar, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC). The chemical composition of EOs was characterized using gas chromatography and gas chromatography/mass spectrometry (GC/MS). The results of EOs analysis indicated that there are different compounds in each EO giving them different characteristics. According to the results, each EO has a different potential to inhibit the growth of bacteria. Among the EOs studied, T. ammi and S. hortensis revealed the strongest antibacterial activity whereas F. vulgare showed the weakest antibacterial activity.'),(1678,'10.1080/10412905.2015.1120691','Chemical composition, antioxidant and antiproliferative activities of essential oil from<i>Schinus areira</i>L. and<i>Minthostachys spicata</i>(Benth.) Epl. grown in Cuzco, Peru','Journal of Essential Oil Research',2015,'https://doi.org/10.1080/10412905.2015.1120691',20,'https://openalex.org/W2289743405','The chemical composition, antioxidant or anti-proliferative activities of essential oils from leaves of Schinus areira L. and Minthostachys spicata (Benth.) Epl. grown in Cuzco (Peru) was studied. Fifty-six and fifty-eight compounds were identified in the essential oils from S. areira and M. spicata leaves, respectively. In S. areira essential oil, monoterpene hydrocarbons were the most represented class of volatiles (58.7%), including α-phellandrene, limonene, camphene, β-phellandrene, α-pinene, p-cymene, and β-pinene as the major components. In M. spicata, oxygenated monoterpenes (87.4%) were the major class of volatiles; among them pulegone, isomenthone, and menthone were the main compounds. Antioxidant activity were examined using 1,1-diphenyl-2-picryl-hydrazyl assay. Essential oil from S. areira was also evaluated for its anti-proliferative activities against murine breast cancer cells (4T1). Our results justify the use of these plants in traditional medicine in Peru and open a new field of investigation in the characterization of the molecules involved in the antioxidants and anti-proliferative processes.'),(1679,'10.1080/10412905.2015.1129991','Terpene constituents of<i>Chrysopogon aucheri</i>(Boiss.) Stapf. roots','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2015.1129991',1,'https://openalex.org/W2309148551','The essential oil content in the roots of Chrysopogon aucheri growing wild in south of Iran was found to be 0.1% based on the fresh weight. The oil was analyzed by Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GC/MS). Twenty constituents were identified, which approximately constituted 97.3% of the root oil. Monoterpenes consist more than 88% of the oil of which the major components were characterized as α-pinene (23.1%), (E)-β-ocimene (20.9%), (Z)-β-Ocimene (12.0%) and α-phellandrene (10.8%).'),(1680,'10.1080/10412905.2015.1129992','Phytochemical composition of the Algerian <i>Laurus nobilis</i> L. leaves extracts obtained by solvent-free microwave extraction and investigation of their antioxidant activity','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2015.1129992',13,'https://openalex.org/W2307010373','This paper focuses the phytochemical composition of bay leaves essential oils obtained by solvent-free microwave extraction (SFME) and by the hydrodistillation (HD) for comparison. Essential oils had similar qualitative but different quantitative composition. For HD and SFME, the main constituents on the oils differed respectively in 1,8-cineole (26.4â30.9)%, sabinene (9â9.6)%, alpha-terpinyl acetate (9.5â7.8)%, linalool (4.9â9.5)%, alpha-terpineol (3.3â7.6)%, alpha-pinene (9.2â4.6)%, methyl eugenol (5â6.2)% and eugenol (1.2â3.6)%. The HD essential oil and SFME volatile extract inhibited nitric oxide production by stimulated mice peritoneal neutrophils (IC50: 6.65 and 13.75) mg/mL and dose dependently scavenged superoxide anion (IC50: 0.048 and 0.058) mg/mL. Inversely, these volatile extracts enhanced myeloperoxidase release (EC50: 0.72 and 0.29) mg/mL. Moreover, the potentiating effect of laurel extracts on exocytosis granules could collaborate in trapping and killing of extracellular pathogens by neutrophils extracellular traps (NETs).'),(1681,'10.1080/10412905.2015.1129993','<i>Helichrysum italicum</i>(Roth) G. Don fil. subsp.<i>italicum</i>oil analysis by gas chromatography â carbon isotope ratio mass spectrometry (GC-C-IRMS): a rapid method of genotype differentiation?','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2015.1129993',13,'https://openalex.org/W2298076382','Helichrysum italicum (Roth) G. Don fil. subsp. italicum oils, coming from Sicily and Corsica and growing up, at equal geographical area, at the same edaphic and climatic conditions, were investigated by GC-MS, GC-FID and gas chromatography carbon isotope ratio mass spectrometry (GC-C-IRMS). GC-MS and GC-FID analyses on the oils terpene fraction have evidenced two different compositional finger prints (chemotypes). Investigating the carbon isotope ratio of the main and common terpene compounds, were also highlighted different plantsâ genetic behaviors. The i-stds elaboration has permitted to investigate on the plantsâ genetic changes, taking into account only the secondary biogenetic pathways, in which the terpenes formation occurs.'),(1682,'10.1080/10412905.2015.1133458','Essential oil composition and enantiomeric distribution of some monoterpenoid components of <i>Juniperus communis</i> L. from Algeria','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2015.1133458',13,'https://openalex.org/W2405058307','The chemical composition of essential oil isolated from the needles of Juniperus commuis L. (Cupressaceae) by hydrodistillation was analyzed by capillary GC-FID and GC/MS. A total of seventy-four compounds representing 93.35% of the oil were identified, the main components from oil were α-pinene (14.2%) followed by sabinene (12.4%), terpinene 4-ol (14.1%), γ-terpinene (5.9%), (2Z,6E) farnesol (5.4%) and manoyl oxide (4.1%). The enantiomeric distribution of α-pinene, sabinene, camphene, β-pinene, limonene, terpinen-4-ol, borneol and myrtenol were successfully determined in essential oil of J. communis.'),(1683,'10.1080/10412905.2015.1133459','Evaluation of the chemical composition of the essential oil from a Brazilian Poejo,<i>Hesperozygis myrtoides</i>(St. Hill ex Benth.) Epling at different collection periods and sites','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2015.1133459',4,'https://openalex.org/W2401206600','Hesperozygis myrtoides is a native species from Cerrado and Atlantic Forest of Brazil. The essential oil from aerial parts of this plant, collected at different periods of the year, was obtained by hydrodistillation and analyzed by GC and CG-MS. The most abundant compounds were limonene (2.1â22.7%), isomenthone (14.3â47.7%), neo-isomenthol (1.8â4.4%), pulegone (19.8â57.3%) and isomenthyl acetate (0.3â14.3%). The chromatographic data were processed using hierarchical cluster analysis (HCA) and principal component analysis (PCA) based on the major compounds. The multivariate analyses (MVA) indicated that the variation of chemical composition of principal substances of H. myrtoides essential oil depends on the altitude. The enantiomeric distribution of (R)-(+)-pulegone and (+)-isomenthone were established for the first time for this essential oil by bidimensional GC-chiral analysis.'),(1684,'10.1080/10412905.2016.1140090','Chemical composition of the leaf essential oil of grapefruits (<i>Citrus paradisi</i>Macf.) in relation with the genetic origin','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1140090',21,'https://openalex.org/W2336285109','International audience'),(1685,'10.1080/10412905.2016.1142477','Composition and antifungal activity of the essential oil of <i>Nashia inaguensis</i> Millsp. (Verbenaceae) cultivated in French Guiana','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1142477',3,'https://openalex.org/W2336566201','This study reports the chemical composition of the essential oil of Nashia inaguensis Millsp. organically cultivated in French Guiana. This essential oil was examined by a combination of GC/FID and GC-MS techniques. A total of thirty-one components accounting for 97% of the total GC/FID chromatogram were identified. The most abundant ones were carvacrol (23.1%), p-cymene (18.7%), γ-terpinene (14.6%), thymol methyl ether (10.3%), thymol (8.3%), trans-β-caryophyllene (8.0%) and myrcene (2.3%). The essential oil of N.inaguensis was tested for the first time for antifungal and antiparasitic activities against strains of several Candida spp. and Leishmania guyanensis respectively: the strong antimicrobial activity of this essential oil was confirmed in vitro by the definition of MIC values ranging from 125 μg/mL to 500 μg/mL according to the Candida species tested, while the anti-Leishmania activity assessed by the definition of an IC50 value seem negligible.'),(1686,'10.1080/10412905.2016.1144543','Chemical composition of essential oil and rose-water extract of Himalayan Musk Rose (<i>Rosa brunonii</i> Lindl.) from Kumaon region of western Himalaya','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1144543',23,'https://openalex.org/W2338047599','Rosa brunonii Lindl. (Rosaceae) is commonly known as âHimalayan musk roseâ or âKunjaâ. Leaf, flower, bark and root of the plant are used in traditional medicine. The aim of this study was to characterize the aroma constituents of flower essential oil and hydrolate (rose-water) extract of R. brunonii growing abundantly in Kumaon region of western Himalaya. Altogether, fifty-two constituents, forming 93.5% of the total oil composition were identified using gas chromatography-flame ionization detector (GC-FID) and GC-mass spectrometry (GC-MS). Major constituents of the oil were eugenol (23.9%), geraniol (19.2%), n-heneicosane (7.7%), n-nonadecane (6.4%) and α-pinene (5.7%). However, main constituents of the rose-water extract were eugenol (52.0%), geraniol (13.3%), phenyl ethyl alcohol (9.4%), n-heneicosane (4.5%) and n-tricosane (3.0%).'),(1687,'10.1080/10412905.2016.1145606','Comparison of microwave-assisted hydrodistillation and solvent-less microwave extraction of essential oil from dry and fresh <i>Citruslimon</i> (Eureka variety) peel','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1145606',38,'https://openalex.org/W2406226053','This study investigated the effectiveness of microwave-assisted hydrodistillation (MAHD) and solvent-less microwave extraction (SLME) for extracting essential oil (EO) from lemon peels in comparison with conventional hydrodistillation (HD) in terms of extraction time, extraction yield, physical properties, chemical composition, operation cost, and antioxidant activity. The results showed that MAHD and SLME methods required an extraction time of 15 minutes while the required extraction time in HD was 120 minutes. There were no significant differences among physical properties (refractive index, specific gravity, and color) of extracted EOs by the three methods. Gas chromatography analysis did not indicate any noticeable change in the composition of EOs extracted by microwave-assisted extraction methods (MAHD and SLME) and HD method. DPPHº analysis of the extracted EOs indicated that microwave irradiation did not adversely influence antioxidant activity of the extracted EOs. The results of this study introduced MAHD and SLME as rapid, economical, and environmentally friendly extraction methods.'),(1688,'10.1080/10412905.2016.1146169','Chemical composition, antioxidant activity and antimicrobial properties of three selected varieties of Iranian fennel seeds','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1146169',33,'https://openalex.org/W2338250406','Essential oils of the seed of three organically grown cultivars of fennel (Foeniculum vulgare var. azoricum, Foeniculum vulgare var. dulce, and Foeniculumvulgare var. vulgare) were examined for their chemical compositions, as well as antimicrobial and antioxidant activities. Gas chromatography/mass spectrometry analysis of the essential oils revealed the presence of eighteen major monoterpenoids in all three cultivars. However, significant differences were observed among percentages of the components. trans-Anethole (61% for azoricum), estragole (57% for vulgare), fenchone (13% for dulce), and limonene (28% for dulce) were highly abundant in all of the examined oils. Antioxidant activities of the essential oils were evaluated through DPPH radical scavenging, lipid peroxidation, and metal-chelating assays. Essential oils from the azoricum and dulce cultivars were more effective antioxidants than those from the vulgare cultivar. Antimicrobial activities of essential oils were measured against two species of fungi, two species of Gram-negative, and two species of Gram-positive bacteria. All three cultivars indicated similar antimicrobial activity. In summary, Iranian fennels have potential for use as natural antioxidants and antimicrobial agents in the industry.'),(1689,'10.1080/10412905.2016.1147391','β-Asarone content and essential oil composition of <i>Acorus calamus</i> L. rhizomes from Estonia','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1147391',12,'https://openalex.org/W2340483946','The rhizomesâ essential oils of Acorus calamus L. grown in Estonia were analyzed using SDE micro-method for oil isolation, GC/FID with two columns of different polarities and GC/MS for identification and quantification of oil composition. The oil yield was 2.4â3.3%. Seventy-two constituents were identified from three A. calamus samples comprising over 95% of the oils. β-Asarone (85.3%) was the major constituent in one sample (a characteristic of tetraploid A. calamus). Two samples (probably triploid caryotype) had lower percentage of β-asarone (9.3â10.2), but more acorenone (22.4â27.5%), shyobunone (8.2â13.7%), preisocalamendiol (8.1%) and isoacorone (2.8â5,0%). Strong negative correlations between the contents of β-asarone and other principal compounds of A. calamus oil were found. The β-asarone-rich chemotype of A. calamus was found to be growing in Europe for the first time.'),(1690,'10.1080/10412905.2016.1150215','Chemical composition and biological activities of rhizome and fruit rind oils of<i>Alpinia mutica</i>from south India','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1150215',4,'https://openalex.org/W2475076328','Volatile oils from dry rhizomes and fruit rinds of Alpinia mutica were isolated and characterized by GC-FID and GC-MS. A. mutica rhizome oil showed forty-seven components of which forty (92.8%) were characterized, and the major components were β-pinene (20.2%), camphor (13.3%), 1,8-cineole (8.9%), camphene (7.9%) and α-pinene (6.2%). Fruit rind essential oil showed sixty-nine components of which sixty-three (97.8%) were identified. Major constituents in A. mutica fruit rind oil were 1,8-cineole (14.8%), camphor (11.7%), β-pinene (7.6%) and camphene (4.8%). Four major constituents in both A. mutica rhizome and fruit rind oils (camphene, β-pinene, 1,8-cineole, camphor) were estimated by external standardization. Refractive index, specific rotation and specific gravity of both volatile oils were determined. Fruit rind oil showed significant antioxidant, cytotoxic and moderate antimicrobial activities. A. mutica dry fruit rind oil has a very pleasant smell with potential applications in fragrances.'),(1691,'10.1080/10412905.2016.1150216','Essential oil composition and antioxidant activity of four Asteraceae species from Bosnia','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1150216',35,'https://openalex.org/W2341628457','Hydrodistilled volatile oils from Achillea millefolium L., Arnica montana L., Artemisia absinthium L., and Artemisia annua L. were analyzed by GC/MS. One hundred sixty-seven compounds were identified in all samples, ranging from 74.3% to 96.4% of the total oil. A high percentage of oxygenated monoterpenes is the main characteristic of A. millefolium and A. absinthium oils with camphor (19.2%) and isoascaridol (21.9%) as the major constituents, respectively. In contrast, the main component of A. annua oil was oxygenated sesquiterpene selina-3,11-dien-6-α-ol (9.6%), while the chemical composition of A. montana oil was characterized by a high content of fatty acids with n-hexadecanoic acid (16.1%) as the main constituent. Antioxidant activity was tested using four different methods, DPPH, ABTS, Reducing power, and Phosphomolybdenum assay. The highest antioxidant activity had essential oil of A. montana using DPPH and Phosphomolibdenum assay, A. millefolium in ABTS method, while A. absinthium oil showed the best ability to reduce Fe ions.'),(1692,'10.1080/10412905.2016.1150217','Essential oil composition and antimicrobial activity of <i>Hyptis atrorubens</i> Poit. from Martinique (F.W.I.)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1150217',9,'https://openalex.org/W2324707467','The volatile constituents obtained by hydrodistillation of the aerial parts of Hyptis atrorubens Poit. growing in Martinique (F.W.I.: French West Indies) were analyzed by a combination of GC/FID and GC-MS. Plants from two different locations in Martinique (North and South) were studied. For the north location, two preparation methods were studied: hydrodistillation in 3L or 20 L reactors and steam distillation. Sixty components representing between 87.7% and 93.2% of the essential oil GC/FID chromatogram total area were identified. The most abundant compounds were caryophyllene oxide (from 5.0 to 31.5%), β-caryophyllene (from 4.7 to 32.6%), palmitic acid (from 2.0 to 9.5%), spathulenol (from 1.5 to 8.5%), α-copaene (from 4.5 to 6.9%), 2-tridecanone (from 0.0 to 6.1%) and phytol (from 2.3 to 4.8%). By comparison with the literature describing a first chemotype rich in Germacrene D and a second chemotype rich in limonene and estragole, in our study Germacrene D was only present at 1.1 and 2.1% in the northern oil. Limonene was present in the oil from 0.1 to 0.3%. Furthermore, no estragole was found in this essential oil. Antimicrobial activity of the essential oil from aerial parts of the plant was also investigated. Antibacterial and antifungal activities were observed against A. niger, C. albicans, S. aureus, E. coli, and B. cereus at 0.5%.'),(1693,'10.1080/10412905.2016.1150218','Analytical and sensory characterization of âPesca di Leonforteâ (<i>Prunus persica Batsch</i>)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1150218',4,'https://openalex.org/W2341315376','AbstractâPesca di Leonforteâ is a Protected Geographical Indication (PGI) product cultivated in the Southern Sicily (Italy). The application for PGI status for âPesca di Leonforteâ is justified by its particular firmness and late ripening characteristic. This research aimed to characterize âPesca di Leonforteâ by quantification of its aroma compounds and the sensory profile. Head-space aroma volatiles were extracted and analyzed by SPME-GC-MS. A large number of compounds have been identified; most of these are well-known in peach fruits, but others have been here identified for the first time. Alcohols, esters and lactones were the most representative chemical classes. The sensory profile of âPesca di Leonforteâ was also defined by a trained panel which assigned high values to peach odor and flavor descriptors. The quantitative data were correlated to the odor descriptors allowing the sensorial characterization of the product. In the samples analyzed esters and lactones prevailed with their sensory descriptors of fruity and peach odor.Keywords: âPesca di Leonforteâpeach aroma volatilesHS-SPME-GC-MSsensory analyses'),(1694,'10.1080/10412905.2016.1153001','Essential oil composition of Hyssop (<i>Hyssopus officinalis</i> L.) under salt stress at flowering stage','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1153001',15,'https://openalex.org/W2338601729','The major environmental abiotic stresses are soil salinity and droughts, the high levels of sodium which are toxic to most varieties of plants species, and more importantly affect plant growth and limit the plants yield capacity. Medicinal plants of recent have received much attention, Hyssopus officinalis has been known as a culinary and medicinal herb for hundreds of years, it is cultivated globally. At presently there is no available research on this plants reaction to soil salinity levels. This study will endeavor to examine in length the effects of salinity on the essential oil contents and composition of H. officinalis. The salinity treatments were five levels at: 0, 2, 4, 6 and 8 dSm-1 saline water from the Hos-e-sultan Lake. The hydrodistilled volatile oils derived from aerial part of H. officinalis at Flowering Stage were investigated by gas chromatography and GCâmass spectrometry. With increasing of salinity essential oil obtained of aerial parts increased. The maximum essential oil amount obtained in EC 6 dSm-1. Thirty-nine components were characterized and isolated, representing 95â99% of the total components detected. The major components identified in the control group and in the treated plants were cis-pinocamphone, β-pinene, β-phellandrene, pinocarvone, myrtenol, elemol, myrcene, linalool and germacrene D.'),(1695,'10.1080/10412905.2016.1155506','Chemical composition, antimicrobial and antioxidant activities of essential oil from<i>Echinophora cinerea</i>harvested at two phenological stages','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1155506',18,'https://openalex.org/W2414889281','Echinophora cinerea (Apiaceae) grows wild in the Zagros Mountains range, located in Iran. The herb has been used as a food additive in traditional preparations such as pickles. This study determined the chemical composition and biological activity of essential oils in the aerial parts of E. cinerea collected from three natural habitats at two phenological stages. The essential oils constituents were determined by GC-FID and GC/MS. The antimicrobial activity of the essential oils was evaluated against Bacillus cereus, Listeria monocytogenes, Proteus vulgaris, and Salmonella typhimurium and Candida albicans. The highest oil yield obtained from E. cinerea was 2.05%w/w dry matter harvested from plants at the full flowering stage. Major essential oil constituents were α-phellandrene (42.40 to 54.87%), α-pinene (12.28 to 25.54%), and β-phellandrene (10.29 to 11.08%).The essential oils of E. cinerea harvested at the full flowering stage of growth had the highest antimicrobial activity. The antioxidant activity of E. cinerea indicated the oil acted as an effective DPPH scavenger. The IC50 values ranged from 1.97 mg/mL to 2.25 mg/mL for the essential oils as compared with the 0.412 mg/mL for BHT. The antimicrobial properties of the essential oils obtained from E. cinerea may be significant from a pharmaceutical standpoint.'),(1696,'10.1080/10412905.2016.1159257','Chemical characterization and anticholinesterase effects of essential oils derived from <i>Salvia</i> species','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1159257',33,'https://openalex.org/W2315301371','Inhibitory effect of <i>Salvia</i> species herbal preparations on acetylcholinesterase (AChE) and butylcholinesterase (BuChE) activitiy may contribute to regulation of cognitive performance and impaired cholinergic functions in patients with Alzheimerâs disease. This functional role of <i>Salvia</i> species and their components makes the investigations on <i>Salvia</i> valuable in medicine-related plant research. Within this work it was aimed to investigate the <i>in vitro</i> anti-cholinesterase effect of essential oils derived from ten <i>Salvia</i> species, which grow in Turkey. The chemical composition of essential oils were characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS), respectively. Results showed that all of the essential oils exhibited AChE inhibitory activity. <i>S. pseudeuphratica, S. hydrangea and S. divaricata</i> essential oils demonstrated the most potent AChE inhibitory effect [50% inhibition concentration (IC<sub>50</sub>) = 26.00 ± 2.00 μg/mL, 40.0 ± 4.00, 64.68 ± 4.16, respectively]. The essential oil of <i>S. pseudeuphratica</i> demonstrated the highest inhibitory activity against AChE and BuChE among the tested <i>Salvia</i> essential oils. Evidences from the our study augment the importance of essential oils obtained from <i>Salvia</i> species and may support utilization of <i>Salvia</i> species for symptomatic treatment of Alzheimer disease.'),(1697,'10.1080/10412905.2016.1161564','Antibacterial activity against methicillin-resistant<i>Staphylococcus aureus</i>of five essential oils from Algerian medicinal plants (Lamiaceae)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1161564',12,'https://openalex.org/W2313977839','The susceptibility of two methicillin-resistant Staphylococcus Aureus (MRSA) and one methicillin-sensitive Staphylococcus Aureus (MSSA) to essential oils (EOs) extracted from five Algerian medicinal plants (Lamiaceae) was evaluated. Thymus fontanesii and Thymus numidicus EOs revealed a carvacrol chemical profile (62.7 and 46.8%, respectively) whereas Origanum glandulosum EO was characterized by high contents of carvacrol and thymol. Mentha pulegium was characterized by a high content of pulegone (74.8%) never put in evidence. The major components of Lavandula stoechas L. were fenchone (48.0%) and camphor (21.1%). Antibacterial activities against MRSA and MSSA were evaluated by disk diffusion method and microdilution broth assay. This is the first report on the antibacterial activity against MRSA for EOs from the species T. fontanesii and T. numidicus and for M. pulegium from Algeria. EOs were found to be strongly bactericidal (MIC from 0.3 μL/mL to 4.7 μL/mL) which suggests an additional option to treat MRSA infections.'),(1698,'10.1080/10412905.2016.1161565','Characterization of essential oils from the leaves of the Genus<i>Daphnandra</i>(Atherospermataceae)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1161565',2,'https://openalex.org/W2436897587','As part of an investigation of the more primitive plant families in Australia the chemical profile of the essential oils from leaves of the six species of the Australian genus Daphnandra have been characterized. Daphnandra apetala gave a sesquiterpenic oil, with β-caryophyllene (9â19%), germacrene-D (15â20%) and bicyclogermacrene (9â12%) constituting the major components. D. johnsonii gave an oil with significant amounts of monoterpenes (α-pinene, 31.7% and camphene, 18.6%) and sesquiterpenes (cubenol, 3.1%, β-caryophyllene, 3.1% and α-, β-, γ-eudesmols, 6.3%, 5.1%, 2.3%, respectively). D. melasmena produced sesquiterpenic oil, with spathulenol (20.4%) and bicyclogermacrene (8.3%) as the principal components. D. micrantha produced a oil with sesquiterpenes (mainly cubebol, 7.4%, spathulenol, 8.3% and germacrene-D, 6.8%) and monoterpenes (mainlyα-pinene, 8.5%, camphene, 8.6%) as the most significant components. D. repandula gave a sesquiterpenic oil of two types; one in which the principal components were bicyclogermacrene (19â24%) and spathulenol (10â15%), and α-, β-, γ-eudesmol present in trace amounts; while a second type contained β-caryophyllene (11â13%) and bicyclogermacrene (22â25%) as the major components and small amounts of α-, β-, γ-eudesmol (each up to 5%).D. tenuipes gave a sesquiterpenic leaf oil with major components being germacrene-D (16â21%) and germacrene-B (16â21%). The oil yield of all species was low, being less than 0.5% (w/w, fresh weight).'),(1699,'10.1080/10412905.2016.1162210','Volatile composition of<i>Lavandula angustifolia</i>produced by different extraction techniques<sup>*</sup>','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1162210',57,'https://openalex.org/W2418793895','The present investigation was conducted to study the quantitative and qualitative characteristics of volatile fractions from lavender flowers (Lavandula angustifolia) produced by different extraction techniques, which revealed that water distillation (WD) produced highest product yields (1.2%) followed by water-steam distillation (WSD) (1.12%), solvent extraction (SE) (0.8%) and supercritical CO2 extraction (SCE) (0.5%). Linalyl acetate, the most important and major ester that determines the quality of lavender aroma, was recorded to be in higher amount in the volatile fraction produced by SCE (51.8%) followed by SE and WSD (31.4%, in each) and WD (26.8%). On contrary, linalool was found highest in the volatile fraction produced by WD (30.9%) followed by SCE (23%), WSD (20.5%) and SE (17.3%). Coumarin and 7-methoxycoumarin, the undesirable constituents in the lavender aroma, were present in substantial amounts in SE (20.5% and 11.2%, respectively) but were absent in hydrodistilled oils. Studies on sequential evolution of chemical constituents during WSD revealed that the distillation process should be continued up to 2 hours to obtain optimum oil yields with better quality. The foregoing studies disclosed that the SCE produced better-quality extracts compared to other conventional techniques that may find potential applications in food and pharmaceutical products.'),(1700,'10.1080/10412905.2016.1164762','Post harvest storage effect on essential oil content and composition of<i>Cymbopogon distans</i>(Nees ex Steud.) Wats.','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1164762',9,'https://openalex.org/W2312989606','The members of Cymbopogon genus are of commercial importance owing to have essential oils, which are highly prized in flavor and fragrance industries. Cymbopogon distans (Nees ex Steud.) Wats. is an under-explored aromatic member of this genus which is found abundantly wild in western and central Himalayan region. The lemon-scented chemotype of C. distans, domesticated in foothills was studied for post harvest storage under shade and open field conditions. The results revealed that there were no losses in essential oil content up to 15 days of storage (0.46%) under shade conditions. However, in field conditions a loss of 6.52% and 10.87% of essential oil was observed over a fresh herb after 7 days and 15 days of storage, respectively. Major constituents of the essential oil, viz.geranial (20.3â25.9%), neral (13.2â17.5%), geraniol(15.3â18.6%), and geranyl acetate (17.2â23.0%) showed change under post harvest storage. In conclusion, C. distans should preferably be distilled a fresh or it may be stored in shade conditions up to 15 days without any loss of essential oil.'),(1701,'10.1080/10412905.2016.1165743','The effect of time and temperature on the shelf life of essential oils of <i>Lavandula officinalis</i>','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1165743',12,'https://openalex.org/W2314376849','Lavender (Lavandula officinalis L.) has carminative, antispasmodic, antidepressant, expectorant, anti-rheumatic, relaxant, sedative, anti-inflammatory and tonic properties. It is a great aid for relaxing and winding down before bedtime. In this research the changes in the composition of essential oils from the aerial parts of Lavandula officinalis were determined at different temperatures and times. The essential oil of air-dried samples was obtained by hydro distillation and analyzed by gas chromatography/mass spectrometry (GC/MS). Changes in essential oils compositions were detected during storage for 4 months in refrigerator, freezer, and at room temperature. The results indicated that at room temperature, the proportions of compounds with lower boiling temperatures such as α-Pinene (2.3â0.2%), Camphene (1.5â0.1%), Sabinene (0.7â0.1%), β-Pinene (1.7â0.3%) and 1, 8-Cineole (24.7â16.2%) were decreased. Furthermore, the essential oil composition showed the least alterations and Lavandula officinalis L. kept its primary quality when stored at low temperatures, particularly in refrigerator.'),(1702,'10.1080/10412905.2016.1165744','Antimicrobial activity of combined thyme and rosemary essential oils against<i>Listeria monocytogens</i>in Italian mortadella packaged in modified atmosphere','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1165744',35,'https://openalex.org/W2415477450','Listeria monocytogenes has been reported as a cause of illnesses related to the consumption raw and processed foods, contaminated during and/or after processing. The ability of L. monocytogenes to multiply at 4°C makes the occurrence in ready-to-eat (RTE) of particular concern. Nowadays, different strategies are applied in order to control pathogens in food products and in particular on the use of essential oils (EOs). The inhibitory effect of thyme and rosemary EOs (0.025% and 0.05%) was determined on a mix of three strains of L. monocytogenes in Italian mortadella packaged in modified atmosphere and stored at 4°C for 30 days. Thymol and p-cymene were the main components of thyme EO, while α-pinene, camphor and eucalyptol of rosemary EO. The use of combined rosemary and thyme EOs exhibited bacteriostatic activity against L. monocytogenes. After 30 days of storage L. monocytogenes charges in treated samples was lower of 2.29 log CFU/g in Group A and 2.79 log CFU/g in Group B compared with control samples. The sensory evaluation, showed the permanence of a strong odor related to EOs used. This work shows that the combined use of thyme and rosemary EOs could be used to control L. monocytogenes in mortadella.'),(1703,'10.1080/10412905.2016.1166157','Essential oil composition of walnut tree (<i>Juglans regia</i>L.)â leaves from Tunisia','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1166157',34,'https://openalex.org/W2318605430','The essential oils (EO) extracted by hydrodistillation from the leaves of walnut cultivated in the region of Mateur (north of Tunisia) have shown that essential oils yield ranging from 0.033% to 0.075%. The analysis by GC-FID and GC-MS identified twenty-nine compounds representing 84.25% of total oil. The major constituents were Caryophyllene oxide (16.9 to 27.4%) followed by βâCaryophyllene (4.0 to 22.5%), Germacrene (1.2 to 9.4%) and β- Pinene (2.8 to 9.5%). The essential oils from Juglans regia L.\' leaves were rich in Sesquiterpene hydrocarbon (13.9 to 39.6%), Oxygenated sesquiterpenes (16.9 to 27.4%) and Alcohols (7.6 to 27.8). The differences in the chemical composition and class might have been derived from varieties, wish have confirmed by statistical analysis. In fact, PCA and HCA analyses show a good discrimination between varieties.'),(1704,'10.1080/10412905.2016.1167130','Chemical-profile variations in essential oils isolated from lemongrass (<i>Cymbopogon flexuosus</i>) biomass and condensate wastewater by re-distillation and solvent extraction techniques','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1167130',19,'https://openalex.org/W2314047572','During steam/hydro-distillation of aromatic crops, a small hydrophilic essential oil fraction escapes into the condensate wastewater. Lemongrass [Cymbopogon flexuosus (Nees ex Steud.) Wats.] condensate waste water obtained after distilling the biomass and collecting the essential oil was subjected to re-distillation and liquid-liquid extraction with n-hexane and ethyl acetate to isolate the dissolved aromatic oil. GC-FID, GC-MS analyses of these oils led to the identification of thirty-seven constituents comprising mostly oxygenated monoterpenes (78.3â90.7%). Neral (35.1%) and geranial (44.3%) predominated in the lemongrass biomass essential oil. 6-Methyl-5-hepten-2-one (7.3â32.9%), neral (26.7â32.9%) and geranial (24.9â33.9%) are the major constituents of the recovered aromatic oils which can be used for isolating citral (51.6â66.8%), for application in cosmetics, botanical pesticides and aromatherapy. The essential oil isolated by re-distillation can serve as a new source for isolation of 6-methyl-5-hepten-2-one (32.9%). Solvent-extracted aromatic oils contained higher amounts of citral (neral + geranial) (62.9â66.8%) relative to re-distilled essential oil (51.6%).'),(1705,'10.1080/10412905.2016.1167131','Essential oil composition of bark and leaves of<i>Cinammoum verum</i>Bertch. &amp; Presl from Mizoram, North East India','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1167131',25,'https://openalex.org/W2335100007','Stem bark and leaf essential oil of Cinammoum verum Bertch. & Presl in Mizoram India was extracted and analyzed for composition. On hydro distillation, 0.87% and 2.13% (w/w) essential oil was yielded from leaves and bark, respectively. Overall, twenty compounds were identified in bark and twenty-one in leaf oil using GC-FID and GCâMS analysis. The major components of bark essential oil were methyl cinnamate (81.87%), linalool (3.90%) and αpinene (2.41%) whereas; linalool (67.60%), methyl cinnamate (17.32%) and αpinene (2.74%) were major components of leaf volatile oil. On comparison of our results with earlier studies on various species of Cinnamon as well as C. verum, marked variations exist not only on identity of compounds but also in their percent share in the composition of essential oil. Our observation indicates possibility of Cinnamic aldehyde and eugenol derivatives rich chemotype (Mizoram) of C. verum. Besides, factors which may affect oil composition are also discussed.'),(1706,'10.1080/10412905.2016.1175385','Leaf oils of the Australian species of<i>Clausena</i>and<i>Micromelum</i>(Rutaceae)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1175385',2,'https://openalex.org/W2336274489','The leaf essential oils of Micromelum minutum, Clausena brevistyla and C. smyrelliana, all growing in Australia, have been investigated. M. minutum gave an oil in which the major components were the sesquiterpenes δ-elemene (3.3â18.6%), β-caryophyllene (4.8â30.3%), germacrene-D (2â15.8%) and germacrene-B (3.9â34.3%).C. brevistyla gave an oil rich in monoterpenes in two cases and sesquiterpenes in a third case. The principal components were myrcene (72.4%) or limonene (83.3%) for the monoterpene varieties and β-caryophyllene (19.4%), α-humulene (4.3%), bicyclogermacrene (9.5%), caryophyllene oxide (7.6%) and spathulenol (10.6%) for the sesquiterpene variety. C. smyrelliana gave an oil which was monoterpenic in nature with the principal component being α-pinene (73.3%), with β-caryophyllene (8.5%) as the next most abundant component.'),(1707,'10.1080/10412905.2016.1175386','Chemical composition and antimicrobial activity of<i>Eucalyptus radiata</i>leaf essential oil, sampled over a year','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1175386',9,'https://openalex.org/W2345350016','This study investigated the seasonal variation of the chemical composition and antimicrobial activity of Eucalyptus radiata leaf essential oil. Young and mature Eucalyptus radiata leaf material was collected monthly (January 2014 to December 2014), hydrodistilled and analyzed using GC-MS. Essential oil yields ranged from 0.14% to 4.31% (w/w). The major compounds were 1,8-cineole (65.7% ± 9.5), α-terpineol (12.8% ± 4.4) and limonene (6.5% ± 2.4). Chemometric tools were used to determine seasonal variations, which showed slight variance in E. radiata chemistry between seasons. The minimum inhibitory concentration (MIC) assay showed that the highest activity was noted against the Streptococci (0.19â2.00 mg/mL) and Lactobacillus acidophilus (0.19â1.75 mg/mL). The activity of the E. radiata leaf essential oil is dependent on the unique ratio of its compounds. The E. radiata leaf essential oil showed good oil yields, a relatively consistent chemical profile and noteworthy antimicrobial activity that rivals other commercial Eucalypt counterparts.'),(1708,'10.1080/10412905.2016.1175977','Investigating the effects of microwave-assisted hydrodistillation on antioxidant and antifungal activities of<i>Tanacetum polycephalum</i>and<i>Artemisia chamaemelifolia</i>essential oils','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1175977',13,'https://openalex.org/W2343002750','Essential oils (EOs) of Tanacetum polycephalum and Artemisia chamaemelifolia were extracted by microwave-assisted hydrodistillation (MAHD). Their antioxidant and antifungal activities were compared to the traditional hydrodistillation (HD). The ultimate EO yields were similar in both extraction methods, but the extraction duration in MAHD was significantly shorter than that of HD (150 min vs. 45 min) as regards both plants. Analysis of EOs by gas chromatography showed significant quantitative differences between their chemical compositions. The differences were a result of utilizing the two different methods of HD and MAHD. The antioxidant activities â reported as inhibitory concentration â of EOs obtained from A. chamaemelifolia and T. polycephalum were in the range of 3.74â3.98 mg/mL and 2.47â2.63 mg/mL, respectively, which showed greater activity than that of BHT (22.19 mg/mL). The antifungal activities of EOs belonging to A. chamaemelifolia and T. polycephalum showed excellent inhibitory effects against Trichoderma harizanum, Byssachlamys spectabilis, Paecilomyces variotii, and Aspergillus oryzae. No significant differences were detected in physical properties, antioxidant activities, and antifungal activities of EOs with respect to both extraction methods. This article stands to introduce MAHD as a fast method that does not have adverse effects on the antioxidant and antifungal activities of the extracted EOs.'),(1709,'10.1080/10412905.2016.1175978','Essential oil composition of <i>Artemisia stelleriana</i> Besser from India','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1175978',5,'https://openalex.org/W2460913555','Artemisia stelleriana Bess. (Asteraceae), commonly known as âdusty millerâ or âbeach wormwoodâ, is a perennial shrub that is used traditionally as a carminative and in the treatment of peptic ulcer. In this study, the essential oil composition of fresh aerial parts of A. stelleriana from India was analyzed using gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). Altogether, fifty-two constituents, forming 92.3% of the total oil compositions were identified, representing 49.5% of monoterpenoids and 42.8% of sesquiterpenoids. 1,8-Cineole (29.5%), germacrene D (5.6%), vulgarone B (3.1%), davanone B (3.0%), artedouglasia oxides (22.5%) viz., artedouglasia oxide A (8.0%), artedouglasia oxide C (5.5%), artedouglasia oxide D (5.0%) and artedouglasia oxide B (4.0%) were identified as the major constituents of the essential oil. This is the first report on essential oil composition of A. stelleriana from India.'),(1710,'10.1080/10412905.2016.1178182','Chemical composition of the leaves and stem bark of<i>Sterculia tragacantha</i>,<i>Anthocleista vogelii</i>and leaves of<i>Bryophyllum pinnatum</i>','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1178182',11,'https://openalex.org/W2481157359','Essential oils obtained from the leaves and stem bark of Sterculia tragacantha (Lindl.), Anthocleista vogelii (Planch.) and from the leaves of Bryophyllum pinnatum (Lam.) using hydrodistillation were analyzed by Gas Chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The percentage yields of essential oils are: S. tragacantha leaves (0.53%), S. tragacantha stem bark (0.73%), A. vogelii leaves (0.53%), A. vogelii stem bark (0.56%) and B. pinnatum leaves (0.57%). A total of thirty-five and eleven compounds representing 91.4% and 90.3% were identified in S. tragacantha leaves and stem bark respectively. The principal constituents in the leaf essential oil of S. tragacantha are: β-bisabolol (13.1%), (E)-geranylacetone (11.3%) and hexahydrofarnesylacetone (9.7%) while the stem bark had hexahydrofarnesylacetone (32.5%), viridiflorol (18.9%) and 1,8-cineole (14.79%) as dominant compounds. A. vogelii leaves and stem bark had twenty-one and eighteen compounds accounting for 96.7% and 98.2% respectively, with 1,8-cineole (24.4%) and viridiflorol (24.2%) for leaves and the stem bark; 2-pentylfuran (13.4%), nonanal (9.5%) and (E)-2-nonenal (9.4%) as the most abundant compounds while twenty-four compounds representing 93.3% were identified in B. pinatum leaves with nonanal (17.3%) and (E)-geranylacetone (13.1%) being the two most predominant compounds.'),(1711,'10.1080/10412905.2016.1178183','Influence of season, drying temperature and extraction time on the yield and chemical composition of âmarmeleiroâ (<i>Croton sonderianus</i>) essential oil','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1178183',17,'https://openalex.org/W2342758851','The Caatinga biome is a source of hundreds aromatic plants with medicinal, food and cosmetics potential applications. One of them is Croton sonderianus which essential oil chemical composition and yielding were studied in function of season of harvesting, pre-treatment temperature and time of extraction. In average, after Gas Chromatography analysis, the four major components were spathulenol (40%), 1,8-cineole (25%), α-pinene (8%) and caryophyllene oxide (6%), but such percentage varied greatly in function of the three parameters studied. Sample submitted to drying pre-treatment at 40°C and 2 hours of extraction time resulted in the highest yielding. Components such as spathulenol decreased near 20% from the dry to rainy season, while for germacrene D its amounts increased in the period. Such results will give support for C. sonderianus management in the field cultivation and essential oil exploration.'),(1712,'10.1080/10412905.2016.1179687','Chemical composition and antimicrobial activity of the essential oil from aerial parts of <i>Micromeria debilis</i> Pomel from Algeria','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1179687',3,'https://openalex.org/W2488668993','For the first time, the chemical composition of the essential oil of aerial parts of Micromeria debilis was determined. The essential oil was obtained by hydrodistillation and analyzed by GC(FID), GC/MS and 13C-NMR. In total, forty-two constituents were identified representing 92.4% of the total oil, β-Pinene (19.3%) being the major monoterpene beside geranial (8.7%) and linalool (6.5%). Germacrene D (11.4%) and (E)-β-caryophyllene (8.0%) were the main sesquiterpene hydrocarbons while oxygenated sesquiterpenes were mainly represented by caryophyllene oxide (8.0%). Eight samples of essential oil of M. debilis collected in two locations exhibited similar chemical composition evidencing a chemical homogeneity. The essential oil showed moderate antimicrobial activity, with MIC values between 2 μL/mL and 6 μL/mL. The lowest MIC values (2.0 μL/mL) were measured for K. pneumoniae, S. typhimurium and C. albicans.'),(1713,'10.1080/10412905.2016.1185470','Intraspecific chemical variability of <i>Pistacia atlantica</i> Desf. subsp. <i>atlantica</i> essential oil from Northwest Algeria','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1185470',10,'https://openalex.org/W2491792727','Leaf samples from sixteen natural populations of Pistacia atlantica Desf. subsp. atlantica were harvested in Northwest Algeria aiming to investigate the intraspecific chemical variability of the essential oil. The essential oils were isolated by hydrodistillation, in yields ranging from 0.10% to 0.42% (v/d.w.) and compositions were further investigated by GC and GC/MS. Terpinen-4-ol (34.7â16.1%), α-pinene (64.8â15.4%), germacrene D (24.5â-19.0%) and E-caryophyllene (23.1%) were found the major components. The two last compounds were never mentioned as main constituents of this subspecies. Multivariate cluster analysis of compositional data evidenced significant differences concerning the compositions of essential oils from leaves of male and female trees and different types of essential oil considering the predominant constituents: (1) terpinen-4-ol; (2) α-pinene/camphene; (3) α-pinene/germacrene D. This chemical diversity should be considered as promising source of specific components and could open up more opportunities for the valorization of this species.'),(1714,'10.1080/10412905.2016.1185471','Essential oils of native and naturalized<i>Lamiaceae</i>species growing in the Patagonia region (Argentina)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1185471',10,'https://openalex.org/W2396833340','This is the first comprehensive study of essential oils of wild aromatic Lamiaceae present in Patagonia, including exotic and native species. The most commonly representatives of this family in Patagonia include one species of the adventitious Origanum vulgare L., three naturalized mints, Mentha rotundifolia L., M. pulegium L. and M. spicata L. and two native species: Clinopodium darwinii (Benth.) Kuntze and Scutellaria nummulariifolia Hook. f. The essential oils were isolated by hydrodistillation of the aerial parts of each of these species collected during 3 years and analyzed by GC-FID-MS. The major components found were menthone (5.4â10.2%) and pulegone (78.3â89.8%) in M. pulegium; piperitenone oxide (75.6â68.7%) in M. rotundifolia; carvone (34.0â70.4%) in M. spicata; sabinene (2.7â5.9%), p-cymene (9.3â36.1%) and linalool (11.3â21.4%) in O. vulgare; pulegone (56.6â72.4%) in Clinopodium darwinii; acetophenone (19.0%) and α-terpineol (9.5%) in Scutellaria nummulariifolia. This is the first report on the chemical composition of the essential oil of S. nummulariifolia.'),(1715,'10.1080/10412905.2016.1189856','Essential oil composition and antioxidant activity in <i>Valeriana jatamansi</i> Jones: influence of seasons and growing sources','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1189856',25,'https://openalex.org/W2413798444','Valeriana jatamansi is a perennial medicinal herb used in traditional and modern medicines for preventing number of diseases. Root samples were collected from wild and cultivated conditions in different seasons (spring, summer and winter) and analyzed for essential oil composition using gas chromatography â Mass spectrometry (GCâMS). Antioxidant activity of essential oil was evaluated using DPPH (1, 1-Diphenyl-2-picrylhydrazyl radical) assay. A total of thirty compounds (constitutes 80.1â92.1% of total essential oil) were detected by GCâMS analysis. Patchouli alcohol (36.6â52.8%) was recorded as a major compound followed by guaiene epoxide (3.6â11.5%), seychellene (4.2â5.6%), α-guaiene (2.2â4.6%), kessane (2.7â3.6%), α-patchoulene (0.1â2.3%), β-selinene (0.8â3.1 β-acoradienol (0.6â2.4%), ar-curcumene (0.7â2.2%), γ-patchoulene (1.4â2.6%), viridiflorol (0.6â2.4%), and α-humulene (0.1â4.6%). Essential oil content was recorded higher during winter season in wild (0.9%) and cultivated plants (0.8%) as compared to other seasons. Antioxidant activity of essential oil measured by DPPH radical activity assay varied (IC50 = 117.5â227.6 μL/mL) among seasons and growing conditions. Winter season is recommended for maximum essential oil yield and spring season for antioxidant activity.'),(1716,'10.1080/10412905.2016.1191382','Chemical composition and biological activity of<i>Eupatorium intermedium</i>essential oil','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1191382',9,'https://openalex.org/W2488854956','This article reports a study on the extraction and evaluation of essential oil obtained from dried flowers of Eupatorium intermedium, a plant native to southern Brazil that belongs to the Asteraceae family. The hydrodistillation achieved a maximum yield of 1.01 wt% of essential oil. Regarding the chemical composition, by a qualitative analysis, the identified substances were α-pinene, sabinene, β-pinene, limonene, caryophyllene (E), germacrene D, spathulenol and caryophyllene oxide. The antioxidant activity of the essential oil obtained was evaluated using the DPPH method, phosphomolybdenum reducing method and total phenolic content. The total phenolic content was 4.26 mg GAE/g of oil. The antioxidant activity obtained by the DPPH method was 0.82 wt%, at a concentration of 250 mg/mL. The antioxidant activity obtained through the reduction of the phosphomolybdenum complex was 1154.69 mg α-tocopherol/g of oil. Antibacterial activity assays were performed using the agar well method. The oil presented antibacterial effects against the Gram-positive bacteria tested.'),(1717,'10.1080/10412905.2016.1191383','Storage conditions of<i>Ocimum gratissimum</i>L. leaves influence the quality of essential oil','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1191383',8,'https://openalex.org/W2550785353','The quality and content of essential oils extracted from medicinal plants can be affected by storage conditions. The present work evaluated the influence of different storage conditions of Ocimum gratissimum leaves on essential oils. The study was conducted in two environments (controlled and natural), in two types of packaging (plastic and paper) during five storage times (0, 3, 6, 9, and 12 months). Also evaluated was the damage caused to the glandular trichomes and the fungal contamination of the stored leaves. For this data set, the study was done using multivariate exploratory analysis PCA, HCA and K-means. Among the environments, the use of paper storage in a natural environment presented a reduction of up to 74.3% in essential oil content and greater damage to the trichomes. The plastic packaging prevented the proliferation of fungi. The best storage condition proved to be a controlled environment from 6 months to 9 months in plastic packaging.'),(1718,'10.1080/10412905.2016.1201546','Chemical composition and scolicidal activity of <i>Zataria multiflora</i> Boiss essential oil','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1201546',46,'https://openalex.org/W2464919773','Zataria multiflora Boiss (Lamiaceae) commonly grows in Iran is a popular medicinal plant with various pharmacological activities mentioned in traditional Iranian medicine and modern phytotherapy. This study was designed to evaluate the chemical composition and scolicidal effects of Z. multiflora essential oil on the protoscoleces of hydatid cysts on an in vitro model. The components of the Z. multiflora essential oil were identified by GC/MS analysis. Protoscoleces were aseptically aspirated from the livers of naturally infected sheep. Various concentrations of essential oil, thymol and carvacrol were used for 5â30 minutes. Eosin exclusion test was used to determine the viability of protoscoleces. The main components were thymol (41.8%), carvacrol (28.8%), and p-cymene (8.4%). Findings showed that essential oil at the concentrations of 12.5 and 6.25 μL/mL killed 100% protoscoleces after 5 and 20 minutes of exposure, respectively. In addition, thymol and carvacrol at the concentrations of 100 μg/mL and 100 μL/mL killed 100% protoscoleces after 10 minutes incubation, respectively. Obtained results in this investigation for the first time demonstrated that Z. multiflora essential oil and its main components might be a natural source for the production of new scolicidal agents.'),(1719,'10.1080/10412905.2016.1202152','Variability of essential oil composition of wormwood (<i>Artemisia absinthium</i>L.) affected by plant organ','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1202152',7,'https://openalex.org/W2466909509','The essential oil composition of leaves and roots of twenty individuals of wormwood (Artemisia absinthium L.) belonging to different chemotypes has been investigated. They were obtained from two accesions coming from Hungarian and Spanish wild populations. Essential oils were extracted by hydrodistillation and analyzed by GC/MS and GC/FID. Results showed a great individual variability of wormwood accesions. Based on leaves, three chemotypes (sabinene + myrcene, β-thujone and new sesquiterpene type accounting up to 80.8% of sesquiterpenic fraction) were found in the Hungarian population and two chemotypes ((Z)-β-epoxyocimene and (Z)-β-epoxyocimene + (Z)-chrysanthemyl acetate types) were present in the Spanish one. The composition of EO of the roots from both locations was predominated by monoterpenic esters (14.5â80.2% and 59.9â90.3%, in Hungarian and Spanish samples respectively) but characteristic quantitative and qualitative differences were present. No relationship was found between the composition of EO of roots and leaves of the same plant.'),(1720,'10.1080/10412905.2016.1210039','Essential oil constituents from high altitude Brazilian species with antimicrobial activity: <i>Baccharis parvidentata</i> Malag., <i>Hyptis monticola</i> Mart. ex Benth. and <i>Lippia origanoides</i> Kunth','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1210039',26,'https://openalex.org/W2500238545','The essential oils from three wild Brazilian plant species from high altitude were obtained by hydrodistillation and analyzed by GC/FID and GC/MS. The most noteworthy volatile compounds from Baccharis parvidentata were sabinene (15.2%), himachalol (10.3%), β-pinene (9.2%) and δ-3-carene (5.7%). The oil from Hyptis monticola was characterized predominantly by trans-caryophyllene (11.3%), (E)-methyl-cinnamate (7.8%), germacrene D (6.9%), limonene (6.6%), α-muurolene (6.4%) and β-pinene (5.6%) whereas the most prevalent components in the oil of Lippia origanoides were (E)-methyl cinnamate (40.0%), hedycaryol (8.0%), α-eudesmol (8.0%) and β-eudesmol (7.0%). Essential oils from B. parvidentata and L. origanoides displayed antibacterial and antifungal activities. Minimal inhibitory concentrations ranged from 78 μg/mL to 2500 μg/mL. Cryptococus neoformans and Trycophyton rubrum were the most sensitive microorganisms. The MIC and the microbicidal concentrations were identical. This is the first report on the chemical composition of Hyptis monticola and Baccharis parvidentata.'),(1721,'10.1080/10412905.2016.1210040','Aromas from Quebec. V. Essential oils from the fruits and stems of <i>Heracleum maximum</i> Bartram and their unsaturated aliphaticacetates','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1210040',0,'https://openalex.org/W2493026470','Both the fruits and stems of Heracleum maximum Bartram, a common Apiaceae found throughout northern North America, have been traditionally consumed as spice and food by American First Nations and settlers. As both parts of the plant bear a distinctive scent, they have been submitted to volatile constituent extraction and their essential oils were studied by GCâFID and GCâMS. The fruitsâ oil was found to be mostly constituted of aliphatic esters, with octyl acetate (65.6%) as main constituent, while the stems yielded a generally terpenic oil, dominated by limonene (45.2%). These results were in line with data for other Heracleum species, and constitute the first study of the volatile constituents of H. maximum. The observation of several octadecenyl acetates as trace compounds in the stemsâ oil allowed for the comprehensive identification of these uncommon and closely related isomers.'),(1722,'10.1080/10412905.2016.1210041','Chemical composition and antiparasitic activity of essential oils from leaves of<i>Guatteria friesiana</i>and<i>Guatteria pogonopus</i>(Annonaceae)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1210041',21,'https://openalex.org/W2496555346','Natural products represent a valuable source for discovery of antiparasitic agents. Here, we describe the antiparasitic activity from essential oils extracted from leaves of Guatteria friesiana (EOGF) and Guatteria pogonopus (EOGP) (Annonaceae). The essential oils were obtained by hydrodistillation and analyzed by GC/MS and GC-FID. The sesquiterpenes are more abundant in both essential oils. G. friesiana are dominated by β-eudesmol (51.9%), γ-eudesmol (18.9%) andα-eudesmol (12.6%). The major compounds identified for EOGP were spathulenol (24.8%), γ-amorphene (14.7%) and germacrene D (11.8%). The essential oils demonstrated potent trypanocidal and antimalarial activities with values of IC50 lower than 41.3 μg/mL. EOGF also inhibits the proliferation of amastigotes. In addition, we identified significant ultrastructural alterations induced by the essential oils, especially in the cell membrane, Golgi complex, endoplasmatic reticulum and mitochondria. The results presented herein reinforce the potential of other members of this family for search of antiparasitic compounds.'),(1723,'10.1080/10412905.2016.1211561','Effect of drought stress on essential oil composition of<i>Thymus vulgaris</i>L. (Chemotype 1, 8-cineole) from wild populations of Eastern Iberian Peninsula','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1211561',29,'https://openalex.org/W2482519787','1,8-cineole defines a typical chemotype of Thymus vulgaris L. in Iberian Peninsula. This compound has a wide range of potentially useful bioactive properties. In order to study the influence of drought stress in the essential oil (EO) composition of this chemotype, sixty plants from six wild populations of Eastern Iberian Peninsula were distilled and analyzed by GC and GC/MS. The harvest dates (May and August) were selected in such a way that the typical summer drought in Mediterranean climates was the critical factor affecting EO composition. Despite the high intrapopulational variability, significant increases of 1,8-cineole were found after the drought period (21.8%â43.2%, in May, up to 42.6%â68.5% in August). On the other hand, individuals from one of the populations showed different profiles rich in linalool and camphor or sesquiterpenoid compounds, such as α-cadinol.'),(1724,'10.1080/10412905.2016.1211967','Analysis of the essential oils of subgenus <i>Caropodium</i> from Turkey; <i>Grammosciadium schischkinii</i> (V.M.Vinogr. &amp; Tamamsch.) V.M.Vinogr., <i>G. haussknechtii</i> Boiss.<i>, G. pterocarpum</i> Boiss. and <i>G. platycarpum</i> Boiss. &amp; Hausskn. ex Boiss.','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1211967',0,'https://openalex.org/W2494711024','The composition of the hydrodistilled essential oils obtained from aerial parts of Grammosciadium schischkinii (V.M.Vinogr. & Tamamsch.) V.M.Vinogr., G. haussknechtii Boiss., G. pterocarpum Boiss. and G. platycarpum Boiss. & Hausskn. ex Boiss. (Apiaceae) which belong to subgenus Caropodium, growing in Turkey, were simultaneously analyzed by GC and GC-MS. The analysis revealed fifty-seven constituents, accounting 84.3â99.5% of the oils. The essential oil composition of G. schischkinii and G. haussknechtii which are endemic taxa to Turkey, have herein demonstrated for the first time. Moreover, we firstly defined the chemical characterization of the essential oil obtained from G. platycarpum gathered from Turkey. Oil samples showed different chemical compositions with regard to species and locations. Linalool (88.5 and 94.2%) was the main component of the oil samples from G. platycarpum, while hexadecanoic acid (20.6%) was the major in the oil sample of G. haussknechtii. Caryophyllene oxide (45.9 and 20.7%) was defined as the principal constituent in the oil samples of G. schischkinii and G. pterocarpum, respectively. In addition, phytol (19.1%) was determined as the main component in the oil of G. haussknechtii and this compound was first determined in the highest amount among the essential oils of the genus Grammosciadium.'),(1725,'10.1080/10412905.2016.1212739','Olfactometry evaluation and antimicrobial analysis of essential oils from <i>Baccharis dentata</i> (Vell.) G.M. Barroso and <i>Baccharis uncinella</i> DC.','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1212739',7,'https://openalex.org/W2493263027','The species of genus Baccharis spp. (Compositae) are an important natural resource in the search for new bioactive compounds. This article presents an investigation of volatile compounds of two species of Baccharis that are native to southern Brazil (Baccharis dentata (Vell.) G.M. Barroso and Baccharis uncinella DC) collected in summer and autumn of 2011. The essential oils were extracted by steam distillation and analyzed by gas chromatography-mass spectrometry (GC-MS), olfactometry analysis (GC-O) and qualitative assessment of the antimicrobial potential using the indirect bioautography method against Staphylococcus aureus, Salmonella enterica subspecie enterica serovar Choleraesuis, Pseudomonas aeruginosa, Candida albicans, Aspergillus niger, Candida parapsilosis, Cryptococcus neoformans, Rhizopus stolonifer, Fusarium solani and Aspergillus oryzae. The results demonstrated that the harvest period has an influence on the composition of the essential oils, but little influence on extraction yield. It can also be observed that the joint analysis of GC-MS and GC-O resulted in complementary information about the essential oils studied because the intensities of volatile compounds detected by both methods are significantly different. Regarding antimicrobial assays, it was found that the essential oil of B. dentata was effective against S. aureus, A. niger, C. parapsilosis and R. stolonifer, whereas the essential oil of B. uncinella was effective against S. aureus, S. Choleraesuis, C. albicans, A. niger, C. parapsilosis, R. stolonifer and F. solani.'),(1726,'10.1080/10412905.2016.1213667','Chemical composition, radical scavenging and anti-oxidant capacity of<i>Ocimum Basilicum</i>essential oil','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1213667',26,'https://openalex.org/W2478193348','Ocimum basilicum has several functional characteristics including carminative, stimulant, diuretic, antiseptic, anesthetic, anti-spasmodic, analgesic and anti-tussive properties. O. basilicum essential oil (basil oil) was tested for chemical composition and in vitro and ex vivo anti-oxidant activities. The in vitro anti-oxidant capacity of basil oil was examined using 1, 1-diphenyl-2-picryl-hudrazyl radical (DPPHâ¢), 2, 2-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) radical (ABTSâ¢), hydrogen peroxide (H2O2), hydroxyl radical (HOâ¢), nitric oxide (NO) and nitrite (NO2) scavenging effects. The ex vivo anti-oxidant activity of basil oil was determined through measuring NADH oxidase (NOX) and inducible nitric oxide synthase (iNOS) mRNA expression in lipopolysaccharide-stimulated murine macrophages using real-time polymerase chain reaction (RT-PCR). GC-MS analysis indicated that the main components in the basil oil were methylchavicol (47%), geranial (19%) and neral (15%). Basil oil had effective DPPHâ¢, ABTSâ¢, H2O2, HOâ¢, NO and NO2 scavenging effects. Basil oil significantly reduced NOX and iNOS mRNA expression in lipopolysaccharide-stimulated murine macrophages at concentrations of 1-10 μg/mL. Basil oil had radical scavenging and anti-oxidant activities and could potentially be used as a safe and effective source of natural anti-oxidants in therapy against oxidative damage and stress associated with some inflammatory conditions.'),(1727,'10.1080/10412905.2016.1216014','Inhibitory effect on corrosion of carbon steel in acidic media, antioxidant, antimicrobial, anti-5-lipooxygenase and anti-xanthine oxidase activities of essential oil from <i>Tetraclinis articulata</i> (Vahl) Masters leaves','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1216014',11,'https://openalex.org/W2486618181','The leaves essential oil of Tetraclinis articulata (Vahl) Masters was analyzed by GC and GC-MS, and then tested as corrosion inhibitor of carbon steel in 0.1 N of HCl, H2SO4 and HNO3, using electrochemical polarization method. It was also screened for possible biological activities especially antioxidant, antimicrobial, anti-5-lipooxygenase and anti-xanthine oxidase activities. Thirty-five components were identified, accounting for 96.6% of the total essential oil. The major components were α-pinene (29.0%), bornyl acetate (25.5%), camphor (16.6%) and limonene (6.7%). The corrosion rate of carbon steel decreased in the presence of the essential oil giving increased inhibition efficiency with increasing essential oil concentration. Polarization curves showed that this essential oil behave as mixed-type inhibitor with dominated cathodic character in the studied acidic media. The investigated essential oil showed substantial antimicrobial activity, which S. aureus was found to be the most sensitive bacteria. Also, this essential oil showed substantial antiradical and reduction activities. In addition, the 5-lipooxygenase and xanthine oxidase were efficiently inhibited by the tested essential oil. According to these finding, this essential oil may be suggested as new green inhibitor agent against corrosion in acidic media and could be considered as a potential natural antioxidant alternative for use in food industry.'),(1728,'10.1080/10412905.2016.1216898','Diurnal variations in aroma profile of<i>Ocimum basilicum</i>L.,<i>O. gratissimum</i>L.<i>, O. americanum</i>L., and<i>O. kilimandscharicum</i>Guerke','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1216898',13,'https://openalex.org/W2509728772','Ocimum spp. are reputed for their essential oils and aroma chemicals that are highly valued in food and flavor industries. This study was conducted to evaluate the diurnal effect on essential oil yield and composition of four Ocimum species, viz. O. basilicum L., O. gratissimum L., O. americanum L., and O. kilimandscharicum Guerke grown at foothills of Uttarakhand, India. Essential oil content and composition were determined and compared as a function of different harvesting times viz. morning (6.00 a.m.), noon (12.00 p.m.), and evening (6.00 p.m.). O. basilicum, O. americanum, and O. kilimandscharicum (camphor type) gave higher essential oil yield when harvested at noon, while in O. gratissimum, higher oil yield was obtained in the evening, followed by noon and morning harvesting. Oil yield in O. kilimandscharicum (eugenol/methyl chavicol) chemotype was found in the order of: morning > noon > evening. Similar to oil yield, significant qualitative and quantitative differences in essential oil composition of O. gratissimum and O. kilimandscharicum chemotypes were observed, while in O. basilicum chemotypes, little quantitative changes in compositions were found due to different harvesting times of the day. The results obtained could be of economic significance for determining the most favorable time for harvesting.'),(1729,'10.1080/10412905.2016.1216900','Characterization of volatile components in Melissa officinalis L. under in vitro conditions','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1216900',9,'https://openalex.org/W2491910207','Lemon balm (Melissa officinalis L.) of the Lamiaceae family is an aromatic plant and widely used for medicinal purposes. This present study aimed to determine the compounds from volatiles of the plant using in vitro induced micropropagated shoots. The volatile components were isolated by microdistillation technique from this economically important M. officinalis seedlings. The main components were determined by GC/FID and GC/MS from herbage A and herbage B as geranial (43.4â44.8%), neral (26.8â30.3%), alloaromadendrene (8.5 and 1.6%), geranyl acetate (7.4 and 5.7%), 6-methyl-5-hepten-2-one (3.5 and 3.5%), and β-caryophyllene (3.1 and 2.3%), respectively. The results obtained are in correlation with the previous studies.'),(1730,'10.1080/10412905.2016.1216901','Compositions of essential oils of<i>Salvia adenophylla, Salvia pilifera,</i>and<i>Salvia viscosa</i>in Turkey','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1216901',13,'https://openalex.org/W2530450549','In the Anatolia folk medicine, Salvia species are used by many people in various villages and towns for the therapeutic value of their essential oils. In this study, water-distilled essential oil of three species of Salvia (Lamiaceae) was analyzed. The analysis was performed using a gas chromatography (GC-FID) and gas chromatographyâmass spectrometry systems, simultaneously. The major components were found as α-pinene (16.2%) and β-pinene (14.4%) for Salvia adenophylla Hedge & Hub-Mor. (endemic); β-pinene (24.9%), myrcene (9.0%), and α-humulene (7.9%) for Salvia pilifera Montbret et Aucher ex Bentham (endemic); α-copaene (13.0%), β-caryophyllene (10.8%), γ-muurolene (9.8%), δ-cadinene, and caryophyllene oxide (8.0%) for Salvia viscosa Jacq.'),(1731,'10.1080/10412905.2016.1222315','Volatile oil features of a naturalized population of parsley [<i>Petroselinum crispum</i>(Mill) Nyman] suitable for breeding','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1222315',5,'https://openalex.org/W2510502330','The chemical composition and the antioxidant activity of the volatile fraction of a naturalized population of parsley [Petroselinum crispum (Mill) Nyman] were assessed and compared in a field trial with those of three commercial cultivars. Volatile oils extracted from the leaves were analysed by GC/FID and GC/MS. A total of twenty compounds were detected in all accessions, being the most representatives the terpenes 1,3,8-p-mentathriene and β-phellandrene and the phenylpropanoid myristicin. The naturalized population differed from the cultivars for the highest yield of volatile oil, which was characterized by the absence of apiole, a lower content of myristicin and the highest amount of 1,3,8-p-mentathriene. The antioxidant activity of the essential oil from the evaluated accessions was very low. Due to its essential oil yield and composition, the naturalized population could be taken into consideration for the starting of a breeding programme.'),(1732,'10.1080/10412905.2016.1222973','Optimization of distillation conditions for better recovery of<i>Acorus calamus</i>L. essential oil','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1222973',6,'https://openalex.org/W2513464390','The comminution and distillation time are two important factors, which affect the essential oil yield and/or composition of aromatic plants significantly. To find out the suitable comminution process and optimum distillation time for isolation of essential oil from Acorus calamus L., an experiment was conducted. The comminuted rhizomes (sliced and powdered) were hydrodistilled for different durations and their yields and compositions were compared. Distillation of uncomminuted rhizome for 8 hours gave 2.37% of essential oil. However, in comminuted rhizomes, yield varied from 2.27 to 6.60% under different distillation durations. The resulting essential oils were analyzed using GC-FID and GC-MS. Twenty-seven constituents, representing 94.7â97.2% of the total oil compositions were identified. Major constituents of the oils were (Z)-asarone (84.8â91.2%), and (E)-asarone (2.5â5.2%). The comminution and distillation time showed noteworthy effect on the essential oil yield; however, they showed no major change on the essential oil composition of A. calamus. It was concluded that powdering of dried rhizomes and effecting distillation for 4 hours are appropriate parameters for extracting maximum essential oil from A. calamus at laboratory scale.'),(1733,'10.1080/10412905.2016.1251503','Chemical composition and antimicrobial activity of the essential oil of <i>Sideritis cypria</i> Post endemic in Northern Cyprus','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1251503',12,'https://openalex.org/W2546467227','In this study, chemical composition and antimicrobial activity of the essential oil of Sideritis cypria, which is an endemic taxon in Northern Cyprus, were investigated. The essential oil obtained by hydrodistillation were analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). In general, the GC and GC-MS analysis illustrated that fifty compounds were identified representing 96.9% of the oil. Major components were epi-cubebol (11.9%), trans-piperitol (8.9%) and pinene (8.1%), respectively. The antimicrobial activity of the essential oil was tested by disc diffusion method against Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922), Bacillus cereus (ATCC 10876), Staphylococcus aureus (ATCC 25923) bacteria and Candida albicans (ATCC 90028) yeast. The results showed that the inhibition zone of S. cypria essential oil against C. albicans at maximum dose (10 μl) was higher than positive control Nystatin. The oil showed similar inhibitory zone to that of the positive control (TMP-SMX) against B. cereus at maximum dosage 10 μl. In addition, the inhibitory effect of the oil against E. coli measured only at the 10 μl as 10.33 ± 0.58. Furthermore, the inhibition zones against S. aureus was ranged from 9.00 ± 2.00 to 24.00 ± 1.73 while P. aeruginosa was found to be resistant in all doses.'),(1734,'10.1080/10412905.2016.1251982','Chemical composition of leaf and bark essential oils of<i>Vepris unifoliolata</i>from Madagascar','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1251982',13,'https://openalex.org/W2547113778','The chemical composition of leaf essential oil of Vepris unifoliolata was characterized by hydrocarbon monoterpenes, α-pinene (60.5%), myrcene (6.8%), limonene (5.1%), (E)-β-ocimene (4.9%) and β-phellandrene (4.7%). The chemical composition of bark essential oil of V. unifoliolata was original and characterized by a high content in heat-sensitive compounds isofuranodiene (43.9%) and germacrone (17.1%). These compounds bearing the (E,E)-1,5-cyclodecadiene structure were known to rearrange and degrade during the GCâFID and GC-MS. The true content of isofuranodiene/curzerene, germacrone/trans-β-elemenone, germacrene A/β-elemene and germacrene B/γ-elemene was evaluated by combination of 13C-NMR data (intensities of signals of selected carbons) and GCâFID. Thus, a correct quantitative analysis of bark oil of V. unifoliolata was provided.'),(1735,'10.1080/10412905.2016.1259664','Volatile constituents of <i>Notobubon</i> and <i>Nanobubon</i> (Apiaceae, tribe Tordylieae)','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1259664',0,'https://openalex.org/W2561664034','The essential oil composition and headspace volatiles from the aerial parts of the genera Notobubon and Nanobubon are reported for the first time. Eleven of the thirteen Notobubon and two of the three Nanobubon species were studied. Oil yields obtained by hydro-distillation ranged from 0.1 to 3.6% of dry weight. Forty-four compounds representing 63.8â96.8% of the total oil were identified from the essential oil of eight species of Notobubon and one species of Nanobubon by GC/MS-FID. p-Cymene was present in all samples of Notobubon but not detected in Nanobubon. GC/GC-ToF-MS headspace analysis of eleven species of Notobubon showed α-pinene (1â48%), β-pinene (2â31%), p-cymene (1â41%), sabinene (1â27%), α-thujene (1â22%), and in one species estragole (78â97%) as the main compounds, while in Nanobubon myrcene (1â37%), limonene (13â30%), 3-methyl-2-methylene-butanenitrile (0â27%), sabinene (1â26%) and α-pinene (1â25%) were identified as major constituents.'),(1736,'10.1080/10412905.2016.1261051','Essential oil composition, antifungal, and seedling growth inhibitory effects of zerumbone from <i>Zingiber zerumbet</i> Smith','Journal of Essential Oil Research',2016,'https://doi.org/10.1080/10412905.2016.1261051',30,'https://openalex.org/W2558860829','The composition of the essential oil isolated from the rhizomes of Zingiber zerumbet Smith was determined using GC and GCâMS. Zerumbone (74.82%), humulene (6.02%), and β-copaen-4α-ol (4.32%) were identified as major compounds. E-Bisabol-11-ol (4.32%), E-bisabol-11-ol (0.92%), β-sinensal (0.57%), and α-himachalene oxide (0.19) were reported for the first time in its oil. Zerumbone was further isolated from the crude mixture of oil and identified by FTIR, NMR (1H, 13C, DEPT, HXCO, and HMBC), and mass (EI-MS) spectral data. Zerumbone showed promising antifungal activity against three phytopathogenic fungi, namely Rhizoctonia solani (EC50, 39.6 ppm), Sclerotium rolfsii (EC50, 59.3 ppm), and Macrophomina phaseolina (EC50, 147.4 ppm) compared with hexaconazole (EC50, 18.3, 13.4, and 4.5 ppm, respectively). Zerumbone has also shown concentration-dependent affect on seedling growth of Phalaris minor Retz., compared with control and Triticum aestivum L. (wheat). Zerumbone strongly suppressed the root and shoot growth of P. minor seedling at 1000 ppm compared with control and wheat. It exhibited no or less effect on the germination of seeds of T. aestivum.'),(1737,'10.1080/10412905.2016.1276026','Effects of distillation times on essential oil compositions of <i>Origanum minutiflorum</i> O. Schwarz Et. and P.H. Davis','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2016.1276026',15,'https://openalex.org/W2570571111','Origanum minutiflorum is an endemic species, grown in west Mediterranean region of Turkey. This plant used mainly in essential oil production and also processed into spices, tea, seasonings etc. The physical and chemical characteristics of essential oil could be varied depending on growing place, harvesting season, climatic condition, extraction procedures etc. In this study, effects of five different distillation times (10, 20, 30, 60, 120 minutes) were investigated. The results showed that amount of essential oil and compositions of them was significantly affected (p < 0.05) by distillation times. Considering the each application, volatile oils were changed from 0.12 to 3.11% and more than 50% of total oil was extracted in 10 minutes of distillation after the beginning of boiling. Twenty-eight components, represent more than 99%, were identified by GC-MS/FID. The main component was carvacrol and ranged from 62.60 to 86.40% depending on distillation times. The other major constituents were p-cymene, γ-terpinene, borneol and their quantities varied between 4.29â8.07%, 1.72â5.12%, 0.27â5.33%, respectively. The results showed that 60 minutes distillation was the most suitable time for essential oil yield and higher carvacrol content. Consequently, distillation time is an important processing factor in order to arrange active compounds at intended values which contribute standardized production.'),(1738,'10.1080/10412905.2016.1278405','Acaricidal activity of essential oils of <i>Bursera graveolens</i> (Kunth) Triana &amp; Planch and <i>Schinus molle</i> L. on unengorged larvae of cattle tick <i>Rhipicephalus</i> (<i>Boophilus</i>) <i>microplus</i> (Acari:Ixodidae)','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2016.1278405',24,'https://openalex.org/W2572878404','The use of bio-derivatives as acaricides would be an effective and safe method of tick control. The acaricidal effect of essential oils obtained from Bursera graveolens (Burseraceae) and Schinus molle (Anacardiaceae), traditionally used by indigenous Ecuadorian medicine as insecticides, was tested on larvae of cattle tick Rhipicephalus (Boophilus) microplus. Essential oils were obtained from mature fruits by hydrodistillation and analyzed by gas chromatography. The acaricidal activity of essential oils against larvae was measured by larval package test with six concentrations of each essential oil. In total, sixteen compounds were identified in B. graveolens and twenty-one in S. molle essential oil. The mortalities of larvae in assays conducted with B. graveolens essential oil ranked from 35.43 to 100%; in S. molle from 5.58 to 100%. The obtained results show a clear and promising acaricidal effect of both essential oils over larvae of R. (B.) microplus.'),(1739,'10.1080/10412905.2016.1278406','Phytotoxic effects of <i>Baccharis psiadioides</i> (Asteraceae) volatiles on different phases of plant development','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2016.1278406',3,'https://openalex.org/W2576819311','Plants produce volatile compounds that can be phytotoxic. These compounds are present in the Asteraceae shrub Baccharis psiadioides Less. essential oil. Therefore, we assessed effects of B. psiadioides essential oil on several phases of Arabidopsis thaliana (L.) Heynh. life cycle. Essential oil chemical composition was verified by gas chromatography. Seeds and seedlings were exposed to volatiles in plates with agar medium whereas juveniles and adults were exposed inside glass chambers in soil. Oil chemical composition revealed monoterpene hydrocarbons as the most abundant chemical category and β-pinene was the major compound (44.65%). Germination and early growth were reduced by volatiles. Most evaluated parameters on juvenile and adult plants were not affected, but growth of juveniles decreased. We conclude that early phases of plant development were sensitive to the volatileâs exposure.'),(1740,'10.1080/10412905.2016.1278407','Essential oil content and its composition in herb of lemon balm (<i>Melissa officinalis</i> L.) breeding strains','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2016.1278407',15,'https://openalex.org/W2578483156','The evaluation of essential oil content and its composition in the herb of lemon balm breeding strains was the goal of the research, with the aim of selecting appropriate genotypes for further breeding programs. In 2013â2014, at the beginning of flowering, the herb was collected from ten randomly selected plants of eight strains bred in the nursery. The essential oil content was estimated after hydrodistillation of dried lemon balm herb, in accordance with the method recommended by the European Pharmacopoeia VI; the essential oil was then subjected to gas chromatography. Both the yield of lemon balm essential oil and its composition showed significant differentiation among the investigated strains. These differences were associated with fluctuations in weather conditions in the years of the research. Higher levels of the main components (neral and geranial), though not of essential oil itself, were observed under higher insolation.'),(1741,'10.1080/10412905.2017.1279989','Chemical composition and antimicrobial activity of the essential oil of <i>Conyza canadensis</i> (L.) Cronquist from Turkey','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1279989',23,'https://openalex.org/W2580453837','The essential oils obtained from the aerial parts and the roots of Conyza canadensis (L.) Cronquist (Asteraceae) at the flowering stage, collected from Turkey were simultaneously analysed by GC-FID and GC-MS. Forty-six components comprising 82.8% of the essential oil from the aerial parts and seven components comprising 96.7% of the roots oil were identified. Major constituents of the essential oil of the aerial parts were found to be limonene (28.1%), spathulenol (16.3%) and β-pinene (9.7%), whereas cis-lachnophyllum ester (86.5%), (2Z,8Z)-matricaria ester (3.9%) and β-pinene (2.3%) were identified to be main constituents in the volatiles of the root parts. In addition, antimicrobial activity of the essential oils was screened against Gram-positive and Gram-negative bacteria as well as one strain of fungus by broth microdilution method. Both of the essential oils exhibited antifungal activity against Candida albicans ATCC 10231 with 0.078 μg/ml MIC values. The highest antibacterial activity was observed by aerial parts oil against Escherichia coli RSKK 234 (MIC: 0.039 μg/ml). This is the first report on the chemical composition and antimicrobial activity of the essential oils obtained from C. canadensis growing in Turkey.'),(1742,'10.1080/10412905.2017.1279990','Seasonal variations of essential oil content and composition in male and female plants of <i>Juniperus communis</i> L. ssp. <i>hemisphaerica</i> growing wild in Iran','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1279990',14,'https://openalex.org/W2582246676','The foliage essential oils (obtained by hydro-distillation) of male and female plants of Juniperus communis L. subsp. hemisphaerica, collected from wild habitat were estimated in three different seasons (spring, summer and autumn). The highest essential oil content was obtained from male plants in spring (3.40%). GC and GC/MS analysis of foliage oils showed that the monoterpenes (77.1â88.7%) were the major groups of compounds, followed by amount of sesquiterpenes (4.3â6.3%). The major constituent of the both male and female foliage oils in spring and autumn was α-pinene. In the samples collected during summer, essential oil was dominated by α-pinene (48.8%) and sabinene (44.5%) for male and female plants, respectively. The concentration of α-pinene in the foliage oils from the male plants was higher than in the oils from the female plants. In the present experiment, the variations chemical composition of essential oil were mainly due to the differences in type of the foliage (extracted from male or female plant) and harvest season. In conclusion, foliage of J. communis L. subsp. hemisphaerica for obtaining higher essential oil content (3.40%), α-pinene (61.69%) and limonene (13.56%) should be collected from male plant during the spring season (or at the flowering stage).'),(1743,'10.1080/10412905.2017.1303405','Chemical composition and FtsZ GTPase inhibiting activity of the essential oil of<i>Piper sarmentosum</i>from Andaman Islands, India','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1303405',11,'https://openalex.org/W2596893033','Chemical composition of essential oils from the leaves, fruits and roots of Piper sarmentosum Roxb. (Piperaceae) growing wild in Andaman Islands, India was investigated by gas chromatography (GC), gas chromatography mass spectrometry (GC-MS) and 13C-nuclear magnetic resonance spectroscopy (13C-NMR). The phenyl propanoid myristicin was identified as the major compound comprising 83.4% in the leaf oil, 84.2% in the fruit oil and 81.2% in the root oil. The sesquiterpenoid β-caryophyllene was present in all the oils, 4.2% in the leaves, 5.7% in the fruits and 4.0% in the roots oil. The major constituent myristicin was isolated and structure was further confirmed by 13C-NMR analysis. The antimicrobial efficacy of myristicin was evaluated by both in vitro and in silico FtsZ inhibition studies. The in vitro assay showed 13.0% FtsZ inhibition by 200-μÎ myristicin and the molecular docking simulation supported the activity of myristicin.'),(1744,'10.1080/10412905.2017.1313178','Chemical composition and biological activities of the essential oils from different parts of<i>Ferulago trifida</i>Boiss','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1313178',26,'https://openalex.org/W2605990470','As a result of GC and GC-MS analysis of the essential oils from different parts of Ferulago trifida Boiss., a total of thirty-three compounds were identified in the flowers (Fl), stems (S), leaves (L) and fruits (Fr) essential oils, of which (E)-β-ocimene (Fl: 37.3, S: 20.7, L: 25.7, Fr: 30.5%), α-pinene (Fl: 16.3, S: 22.6, L: 19.6, Fr: 18.0%) and bornyl acetate (Fl: 9.4, S: 8.5, L: 16.7, Fr: 11.0%) were main compounds. Among the thrity-eight compounds identified in the roots essential oil, suberosin (20.7%), β-barbatene (6.6%) and cuparene (6.1%) were main compounds. All essential oils exhibited weak DPPH free radical scavenging activity (IC50: 95â120 µg mlâ1). Among the tested samples flowers, fruits and roots essential oils by 72.1, 78.7 and 74.3% inhibition of Ach Enzyme, respectively, exhibited considerable AChE inhibitory effects in Elman method. They had moderate cytotoxic activity (IC50: 15â55 µg mlâ1) on cancerous cell lines (MCF-7, A-549 and HT-29) in MTT assay.'),(1745,'10.1080/10412905.2017.1313786','Chemical diversity of wild populations of<i>Elionurus muticus</i>(Spreng.) and the allelopathic effect of its essential oil','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1313786',8,'https://openalex.org/W2607260566','Elionurus muticus is a native grass from Brazil that has been shown to have large variability in the chemical constituents of its essential oil. However, few studies have evaluated this species. The aims of this study were to chemically characterize four wild populations of E. muticus that were collected in southern Brazil as well as to evaluate the allelopathic effect of the essential oil, which is rich in citral. Chemical analyses were performed using gas chromatography and mass spectrometry. The phytotoxic activity was evaluated with onion and lettuce seeds. The results showed that the studied populations have chemical variability based on their geographic origin, which indicates the possibility of chemotypes. The results obtained with E. muticus essential oil, reveals phytotoxic activity on the germination and growth of lettuce and onion.'),(1746,'10.1080/10412905.2017.1322007','Chemical composition of the essential oils of <i>Baccharis</i> species from southern Brazil: a comparative study using multivariate statistical analysis','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1322007',19,'https://openalex.org/W2623249037','Baccharis articulata Pers., Baccharis trimera (Less) DC., Baccharis milleflora DC., Baccharis oblongifolia Pers., Baccharis anomala DC., Baccharis calvescens DC., Baccharis uncinella DC., Baccharis axillaris DC., Baccharis mesoneura DC. and Baccharis myriocephala DC. essential oils were obtained by hydrodistillation. Using gas chromatography/flame ionization detector (GC-FID), a total of 48 constituents were identified, representing for 70.3â96.7% of the chemical composition. The yield of essential oil from fresh leaf ranged from 0.02% (B. myriocephala) to 1.89% (B. uncinella). Limonene was the main constituent in all species, while α-thujene, α-pinene, sabinene, β-pinene, myrcene, p-cymene, limonene, (E)-β-ocimene, γ-terpinene, spathulenol and α- cadinol were identified in all samples. Principal Components Analysis and Cluster Analysis revealed that chemical similarity was highest for B. calvescens, B. myriocephala, B. trimera, B. milleflora, B. anomala, B. oblongifolia, B. articulata and B. uncinella.'),(1747,'10.1080/10412905.2017.1322008','Antifungal activities of essential oils and hydrosol extracts of<i>Daucus carota</i>subsp.<i>sativus</i>for the control of fungal pathogens, in particular gray rot of strawberry during storage','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1322008',38,'https://openalex.org/W2614000273','The aim of this study was to investigate the chemical composition of essential oils and hydrosol extract of Daucus carota subsp. sativus, and as well as their biological activities. The major compounds of root oil were geranyl linalool (50.3%). Aerial parts essential oil was made of alismol (15.2%), α-humulene (9.5%) and β-ionone (8.2%). The main components of root hydrosol extract were myristicine (17.8%), (E)-methyl-iso-eugenol (16.6%) and methyl-eugenol (11.9%). Furthermore, caryophyllene oxide (9.8%) and p-cymen-8-ol (8.9%) were the major compounds of hydrosol extract from aerial parts. The hydrosol extract of roots produced the best inhibition against P. expansum and B. cinerea. While, essential oil of roots was inhibitory at relatively higher concentrations. Results showed that the treatments of strawberry fruit with roots essential oil and hydrosol extract of D. carota subsp. sativus presented a very interesting protective and preventive activity on strawberry against B. cinerea mould.'),(1748,'10.1080/10412905.2017.1322009','Effects of microwave heating on the antioxidant and insecticidal activities of essential oil of <i>Origanum glandulosum</i> Desf. obtained by microwave steam distillation','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1322009',13,'https://openalex.org/W2613787152','Response surface methodology (RSM) was used for the first time to investigate the efficiency of a new process developed in our laboratory: Microwaves Steam Distillation (MSD) on the oregano essential oil extraction. The selected parameters are steam flow, microwave power and extraction time, the response is essential oil yield. According to the statistical method, a second-order polynomial function was assumed to approximate the yield. The coefficient of determination R2 (91.33%), revealed a quite agreement between experimental and predictive values. Optimal conditions were: 6 g. min-1 for steam flow, 300 W for microwave power and 8 min for time. DPPH tests showed that MSD oil was the most efficient than eugenol, SD oil and the main compounds (carvacrol and thymol), and has comparable antioxidant activity to that of BHT. In the other hand, MSD and SD oils have an insecticidal effect against Rhizopertha dominica, but SD oil was most efficient.'),(1749,'10.1080/10412905.2017.1331868','Optimization, characterization and biological properties of phenolic compounds extracted from<i>Rosmarinus officinalis</i>','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1331868',7,'https://openalex.org/W2619389832','This study evaluated the optimal conditions for the extraction of phenolics from Rosmarinus officinalis. Phenolic extracts were obtained under extraction conditions in which several parameters were varied (time, temperature, solvents and free and bound forms). The results revealed that the optimum conditions for maximum phenolic content extraction and antioxidant activity were achieved using a mixture of methanol and water at 60 °C/1 h. However, the optimal extraction conditions for phenolics with the highest hypertensive (ACE) or diabetic (α-amylase and α-glucosidase) enzyme inhibitory activity were observed using a mixture of acetone and water for extraction at 40 °C/6 h or methanol at 50 °C/8 h, respectively. The results indicated that the free and bound phenolic compounds had antioxidant, antihypertensive and antidiabetic properties. The predominant free phenolic compound identified in rosemary was thymol, while chlorogenic and caffeic acids were the predominant bound phenolic compounds.'),(1750,'10.1080/10412905.2017.1338625','<i>Kundmannia sicula</i> (L.) DC: a rich source of germacrene D','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1338625',76,'https://openalex.org/W2647639924','Objective: Kundmannia sicula is an herbaceous plant belonging to the family Apiaceae and is distributed in the Mediterranean coastal areas where it occurs in arid places. In this work, we have analysed the essential oil distilled from the aerial parts of K. sicula from Sicily (Italy) and its biological activity. Methods: GC-MS was used to analyze the chemical composition, whereas its antioxidant capacity and cytotoxicity on three human tumour cells (A375, MDA MB-231 and HCT 116) were evaluated by DPPH, ABTS, FRAP and MTT methods, respectively. Result: The essential oil resulted very rich of the sesquiterpene hydrocarbon germacrene D (81.2%). Moreover, the K. sicula oil displayed relevant scavenging activity towards the ABTS radical (IC50 values of 14.5 μg/ml) and noteworthy antiproliferative effects on tumour cell lines (IC50 values in the range 21.59â31.94 μg/ml). Conclusion: Results of this study may support uses of K. sicula as a natural source of germacrene D to be exploited on an industrial level.'),(1751,'10.1080/10412905.2017.1340197','Chemical profiles of essential oils of marjoram (<i>Origanum majorana</i>) and oregano (<i>Origanum vulgare</i>) obtained by hydrodistillation and supercritical CO<sub>2</sub>','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1340197',30,'https://openalex.org/W2667311045','The objective of this work was to evaluate and compare the chemical profile of essential oils of marjoram (Origanum majorana) and oregano (Origanum vulgare) obtained by hydrodistillation and supercritical CO2. The yield of marjoram and oregano essential oils obtained by supercritical CO2 was higher than those from hydrodistillation. Both essential oils presented similar chemical profiles. The major compound was terpinen-4-ol in essential oil obtained by hydrodistillation and cis-sabinene hydrate in the essential oil obtained by supercritical CO2, to both species. The hydrodistillation method showed higher quantitative differences between the extraction fractions in relation to the supercritical extraction. The extracts obtained by supercritical CO2 presented higher concentrations of oxygenated monoterpenes, without significant differences between fraction 1 and 2. A comparison between the extraction methods showed a higher extraction capacity of monoterpene hydrocarbons by hydrodistillation and oxygenated monoterpenes by supercritical extraction, allowing optimizing the extraction of compounds of interest by the choice of the most adequate extraction method.'),(1752,'10.1080/10412905.2017.1353448','Commercial and wild Sicilian<i>Origanum vulgare</i>essential oils: chemical composition, antimicrobial activity and repellent effects','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1353448',32,'https://openalex.org/W2739235963','The composition of two different Origanum vulgare essential oils (EOs) was analysed by gas chromatography-flame ionization detection (GC-FID) and gas chromatography-mass spectrometry (GC-MS); their repellent and antimicrobial effects were evaluated against adults and late-instar larvae of Tribolium confusum and adults of Sitophilus oryzae (Insecta: Coleoptera), Gram-negative and -positive bacteria Pseudomonas fluorescens, Escherichia coli, Staphylococcus aureus, Bacillus cereus and the pathogenic fungi, Penicillium digitatum and Aspergillus flavus. The main constituents of the essential oil from the first sample (obtained by hydrodistillation of inflorescences of wild Sicilian O. vulgare) were thymol and γ-terpinene wherein main component of the second one (a commercial essential oil) was carvacrol. The two tested oils showed relevant antimicrobial and repellent activity, with variable efficacy depending on chemical composition, concentration, targeted species and exposure time. Based on the obtained results, the study extends knowledge on oregano EOs for their potential use as food protectants during storage.'),(1753,'10.1080/10412905.2017.1360216','Microwave assisted hydro-distillation of essential oils from fresh ginger root (<i>Zingiber officinale</i>Roscoe)','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1360216',20,'https://openalex.org/W2748801816','A solvent free in situ microwave hydro-distillation method for extraction of essential oil from fresh ginger root it presented. Extraction was conducted in a TE10n single-mode microwave cavity and variable power 2 kW generator operating at 2.45GHz. The main extracted components identified by gas chromatography (GC) were Zingiberene, α-Curcumene, β-Sesquiphellandrene and α-Selinene. At energy inputs of 0.40 kWh/kg higher powers and shorter exposure times, crucially did not degrade the highly volatile components (α-Pinene and Camphene) despite providing the highest essential oil yields. Optimum processing conditions were found to be 1000W (0.40kWh/kg) for 5 min, for whole ginger root, where 0.35g oil/100g plant was obtained. This was compared to a yield of 0.2g/100g plant in 150 in using conventional hydro-distillation and 0.3g/100g plant in 90 min using a multi-mode microwave cavity-based hydro-distillation.'),(1754,'10.1080/10412905.2017.1360217','Evaluation of supercritical fluid extraction of tacamahaco (<i>Protium heptaphyllum</i>) resin','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1360217',3,'https://openalex.org/W2747375462','An experimental design 23 was developed to investigate the effect of operating pressure (80â100 bar), operating temperature (40â60 °C) and static extraction time (30â35 min) on extraction yield and on its quality during supercritical carbon dioxide extraction from the resin of Protium heptaphyllum (Aubl.) March. The response variables were extraction yield and the quality of the extract measured as the concentration of p-cymen-8-ol. The statistical analysis showed which individual factors had significant effects. The central composite design performed produced a surface response for optimal extraction measured for the percentage of p-cymene-8-ol at 43 °C, a pressure of 106.8 bar and a static time of 36.63 min. A perfume was formulated according to international guidelines with the extract obtained by supercritical fluid extraction and a market survey with a sample of sixty-seven subjects was carried out to find its level of acceptance from the public.'),(1755,'10.1080/10412905.2017.1363090','Variation in essential oil composition of coriander (<i>Coriandrum sativum</i>L.) varieties cultivated in two different ecologies','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1363090',18,'https://openalex.org/W2742741314','Coriander, Coriandrum sativum L, is an important medicinal plant belonging to Apiaceae family, which is grown in many parts of Turkey. In this study, essential oil and composition of 6 Turkish coriander cultivars (Gamze, Arslan, Erbaa, Pelmus, Kudret, Gürbüz) were examined in two different (Mardin and Tokat) ecologies. Essential oils were isolated with distillation method in maturated fruits and component composition was determined with gas chromatographyâmass spectrometry (GC-MS). Main component was linalool in all cultivar, and it was higher in the conditions of Mardin having a warmer climate in all the cultivars than that of Tokat with temperate climate. Contrary to linalool, α-pinene and neryl acetate contents of all cultivar were higher in Tokat.'),(1756,'10.1080/10412905.2017.1371086','Chemical composition and biological activities of <i>Guatteria elliptica</i> R. E. Fries (Annonaceae) essential oils','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1371086',10,'https://openalex.org/W2760960861','Leaf from two Guatteria elliptica R. E. Fries (Annonaceae) specimens were collected at Paranapiacaba and Caraguatatuba in São Paulo (Brazil). The essential oils presented (GC/GC-MS), as major compound, spathulenol (53.9%) for the Paranapiacaba specimen and caryophyllene oxide (40.9%) for Caraguatatuba. The oils showed low antioxidant activity with EC50 = 7.24 ± 1.03 and 28.68 ± 5.78 mg/mL, respectively, for Paranapiacaba and Caraguatatuba specimens. Both oils did not show a relevant (MIC > 3 mg/mL) antimicrobial activity. However, the Paranapiacaba oil presented an important antitumour activity against breast and prostate cancer cells (IC50 = 7.01 ± 0.23 and 5.35 ± 0.35 μg/mL, respectively) and a low cytotoxicity against normal fibroblast cells (IC50 > 22.27 e IC10 = 18.55 ± 1.89 μg/mL). Isolated major compound, spathulenol, showed good activity against MCF-7 and PC-3 with IC50 = 5.38 ± 0.20 and 2.25 ± 0.28 μg/mL μg/mL, respectively.'),(1757,'10.1080/10412905.2017.1371087','Chemo-divergence in essential oil composition among germplasm collection of five<i>Ocimum</i>species from eastern coastal plains of India','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1371087',10,'https://openalex.org/W2763278407','The present work was aimed to study chemical diversity among Ocimum species collected from Eastern Coastal Plains of India. Seventeen accessions representing five Ocimum species namely; O. basilicum L., O. tenuiflorum, O. gratissimum L., O. americanum L. and O. citriodorum Vis. were investigated for essential oil content and oil composition by GC/FID and GC/MS. Essential oil content isolated from aerial parts of Ocimum species varied from 0.27% to 0.47% on fresh weight basis. A total of eighty-three compounds, constituting 95.2â99.9% of total oil were identified in five Ocimum species. Major volatile constituents identified were monoterpenoids (camphor, linalool, neral, nerol, geraniol, 1,8-cineole, ocimenes) and phenylpropanoids (methyl chavicol, eugenol, methyl eugenol, methyl cinnamate). Ocimum species germplasm was classified into different chemotypes. O. americanum accessions belonged to camphor-rich chemotype (38.7â51.4%); while O. gratissimum belonged to eugenol-rich chemotype (59.7â71.8%). A unique high (E)-methyl cinnamate-rich chemotype (61.3â69.0%) was identified in O. basilicum whereas eugenol and methyl eugenol-rich two chemotypes were identified in O. tenuiflorum germplasm. Essential oil profiling of O. citriodorum showed two distinct chemotypes rich in geranial/neral and methyl chavicol.'),(1758,'10.1080/10412905.2017.1372314','Chemical diversity and antimicrobial activity of the essential oils of four Apiaceae species growing wild in Lebanon','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1372314',25,'https://openalex.org/W2759631864','The Apiaceae species are largely used in folk medicine to treat many diseases, including microbial infections. The essential oils (EOs) of Prangos asperula Boiss., Daucus carota L. subsp. maximus, Ferula elaeochytris Korovin and Smyrnium olusatrum L. were analysed by GC, GC-MS and NMR. The major components were as follows: sabinene (29.8%) and β-phellandrene (19.2%) were found in the P. asperula fruit oil; α-pinene (27.4%) and carotol (26.3%) were found in the D. carota flower oil; α-pinene (71.8%) was the major compound in the F. elaeochytris fruit oil; and the S. olusatrum flowerings tops EO was mainly composed of furanodiene (44.6%) and furanoeremophil-1-one (28.5%). D. carota and S. olusatrum were the most active oils especially against Staphylococcus aureus and the dermatophytes; the MIC values ranged from 8 to 64 μg/ml. Some of these EOs constituents hold promising antimicrobial potentials, confirming the traditional medical use of the plants.'),(1759,'10.1080/10412905.2017.1375035','p-Menthenols chemotype of <i>Cymbopogon distans</i> from India: composition, antibacterial and antifungal activity of the essential oil against pathogens','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1375035',15,'https://openalex.org/W2761887098','Cymbopogon distans (Nees. ex. Steud.) W. Watson (family: Poaceae) is a perennial aromatic grass widely distributed in tropical and subtropical zones of north-western Himalaya. The essential oil of C. distans has industrial potential for aromatherapy, fragrances and for natural aroma isolates. In view of chemotypic variations and industrial potential of the essential oil of C. distans, the present study was carried out to investigate the variability in chemical composition of p-menthenols chemotype of the C. distans harvested in different seasons during annual growth, and to evaluate the antimicrobial potential of its essential oil against pathogenic bacterial and fungal strains. The major constituents identified in essential oil of C. distans were cis-p-menth-2-en-1-ol (24.5â26.7%), δ-2-carene (19.9â28.2%), cis-piperitol (10.9â23.6%), trans-p-menth-2-en-1-ol (8.4â13.3%) and trans-piperitol (5.4â7.3%). The essential oil showed antagonist activity against nine bacterial strains (MIC: 250â1000 μg/mL) and three fungal strains (MIC: 130â530 μg/mL). Results revealed that the essential oil of C. distans possessed >50.0% of p-menthenols viz., cis-p-menth-2-en-1-ol, trans-p-menth-2-en-1-ol, cis-piperitol and trans-piperitol as major constituents, with a significant antimicrobial potential for pathogenic microbial strains.'),(1760,'10.1080/10412905.2017.1383315','Stable variety selection over locations and recommendations for rose-scented geranium (<i>Pelargonium graveolens</i>Lâ Herit. ex Aiton.)','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1383315',6,'https://openalex.org/W2765852096','Objective: In this study, productivity and essential oil quality of rose-scented geranium (Pelargonium graveolens Lâ Herit. ex Aiton.) varieties, namely CIMAP Bio-G-171, CIM-Pawan and Bourbon were assessed and compared in two locations of north India. Methods: A field experiment was conducted to evaluate the productivity, while the chemical composition of the essential oils was assessed by GC-FID and GC-MS. Result: Yields of fresh leaves and essential oil from CIMAP Bio-G-171 were significantly higher (173.64â174.42 q h-1 and 69.93â79.06 l h-1) than those of CIM-Pawan (158.08â160.56 q h-1 and 55.57â64.46 l h-1) and Bourbon (133.34â139.33 q h-1 and 44.19â48.38 l h-1). Major constituents of the oils were citronellol (20.9â39.5%), geraniol (10.9â26.5%), linalool (2.9â14.2%), isomenthone (7.4â9.4%), citronellyl formate (5.5â9.1%) and 10-epi-γ-eudesmol (5.2â9.0%). Conclusion: The essential oil yields and chemical compositions were substantially influenced by variety and location of growing. The variety CIMAP Bio-G-171 showed improvement up to 58.2â63.4% and 22.6â25.8% in essential oil productivity over the existing prevalent varieties, Bourbon and CIM-Pawan, respectively.'),(1761,'10.1080/10412905.2017.1386131','Identification of volatile profiles of Rio Red grapefruit at various developmental to maturity stages','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1386131',21,'https://openalex.org/W2768708416','Grapefruit is an important citrus crop having unique aroma and flavour. In the current study, the juice quality parameters and volatile chemical composition of grapefruits harvested at five different periods comprising of developmental to maturity stages from June to April were studied. The headspace volatile compounds of grapefruit juice were isolated by solid phase micro-extraction (SPME) using divinylbenzene-carboxen-polydimethylsiloxane (DVB-CAR-PDMS) fibre and identified by gas chromatography-mass spectrometry. The volatiles were separated on WAXPlus capillary column and the results were relatively quantified and expressed as perillyl alcohol equivalents. A total of 25 compounds were identified constituting to nearly 98% of the volatiles. Terpene hydrocarbons accounted for nearly 98% of total volatiles during the various harvest stages. Limonene and β-caryophyllene were found to be most abundant components in all the samples. The levels of limonene (22.3 ± 2.8â5.9 ± 1.4 mg/100 g fresh weight) decreased from June to April, whereas nootkatone was significantly higher in January (19.9 ± 4.1) and April (56.42 ± 6.31 μg/100 fresh weight) as compared to other harvests. Developmental stages and maturity had significant influence on the volatile profile of grapefruit juice.'),(1762,'10.1080/10412905.2017.1391720','Chemical composition and biological evaluation of the Tunisian <i>Achillea cretica</i> L. essential oils','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1391720',11,'https://openalex.org/W2766155099','The essential oils (EOs) of different organs (flowers, vegetative parts (stems + leaves) and roots) of Achillea cretica were investigated. Antioxidant and antimicrobial activity of the essential oils were also evaluated. They have been analyzed by a combination of GC and GC/MS. Twenty-five, twenty-nine and twenty-five compounds, accounting for 97.9%, 98.80% and 96.20% of the root, (stem + leaf), and flower oils, were identified, respectively. The EOs were rich in monoterpenes (camphor, borneol, camphene and 1,8-cineola) and camphor was identified as a major constituent. Furthermore, the antioxidant activity was evaluated by DPPH, ABTS and ferric reducing assays. The isolated oils showed significant radical-scavenging activity evidenced by IC50 value for ABTS radical (in between IC50 =62 µg/mL and IC50 = 70 µg/mL). The antibacterial activity was tested against two Gram-positive and three Gram-negative bacteria using the broth dilution method. The flowers essential oil shows an excellent inhibitory effect on S. aureus.'),(1763,'10.1080/10412905.2017.1391721','Subcritical CO<sub>2</sub> extraction of a volatile oil-rich fraction from the seeds of <i>Nigella sativa</i> for potential pharmaceutical and nutraceutical applications','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1391721',10,'https://openalex.org/W2765246001','Seeds of black cumin (Nigella sativa L.) were subjected to subcritical CO2 extraction (SbFE) at 70 bar and 30 °C for 2 h in a trial to isolate a volatile oil-rich fraction. That treatment led to obtaining an oleoresin which constituted 1.74 wt.% of the total seedsâ weight and was found to be rich in its volatile oil content (66.6 wt.%). Traditional methods of extracting the oleoresin using n-hexane at room temperature or at 60 °C led to much higher yields (23.6 and 32.9 wt.%), respectively. The volatile oilsâ content of these oleoresins was 4.75 and 3.59 wt.%. GC-MS analysis showed that the volatile oil obtained after SbFE is characterized by the highest thymoquinone (TQ) content (60.5%) compared to that obtained after hexane extraction at room temperature (37.6%) or at 60 °C (41.6%). On the other hand, TQ content of the volatile oils isolated directly from the seeds by hydrodistillation and steam distillation was much lower (10.2 and 23.7%), respectively. Based on the above mentioned, SbFE of N. sativa seeds was found to be a useful green tool for obtaining a volatile oil-rich oleoresin with high TQ percentage which can be applied in pharmaceutical and nutraceutical products.'),(1764,'10.1080/10412905.2017.1399169','Compositional variability in inflorescence essential oil of <i>Coriandrum sativum</i> from North India','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1399169',12,'https://openalex.org/W2769320753','Inflorescence of Coriandrum sativum collected from five locations of North India was hydrodistilled and analysed by GC and GC-MS to assess their chemical diversity. The GC and GC-MS analysis revealed the presence of 30 compounds representing 92.9â98.5% of the total oils. The highest concentration of linalool (62.1%) was found in the essential oil from Haldwani. Linalool (32.7%), citronellol (22.9%) and caryophyllene oxide (13.5%) were the principal constituents of Moradabad oil. Citronellol (22.87%), caryophyllene oxide (22.6%) and cis-4-decenal (11.9%) were the major essential oil constituents of the oil collected from Didihat while, linalool (19.1%), (2E)-dodecenal (28.7%), (2E)-decen-1-ol (11.8%) and caryophyllene oxide (11.7%) were the dominant constituents in the essential oil of plant collected from Pithoragarh. The investigations based on chemical diversity of the oils provide an opportunity to commercially exploit this diversity based on the requirements of the fragrance, flavour and pharmaceutical industries.'),(1765,'10.1080/10412905.2017.1408501','Chemical composition and insecticidal activity of edible garland (<i>Chrysanthemum coronarium</i> L.) essential oil against the granary pest <i>Sitophilus granarius</i> L. (Coleoptera)','Journal of Essential Oil Research',2017,'https://doi.org/10.1080/10412905.2017.1408501',10,'https://openalex.org/W2773564238','The essential oil composition and biological activities of Chrysanthemum coronarium L. from three locations in Cyprus were investigated. A total of 35 components were identified in the oils representing 86.2 ± 0.7%â93.8 ± 0.0% (n = 3) of the oils. Camphor 25.2 ± 0.1%â9.1 ± 0.3%, santolinatriene 21.7 ± 0.1%â3.6 ± 0.1%, yomogi alcohol 12.6 ± 0.1%â3.6 ± 0.1%, cis-chrysanthenyl acetate 10.7 ± 0.1%â6.8 ± 0.1% and bornyl acetate 11.0 ± 0.5%â5.7 ± 0.0% were identified as the main components. Highest DPPH scavenging and PRAP activity was observed for the LefkoÅe sample (49.59 ± 0.19% (n = 5) and 812.77 ± 4.34 AU (n = 5)). Highest phytotoxic activity against Lemna minor L. was observed for the Salamis sample (100.0%). LefkoÅe sample showed the highest insecticidal activity (97.82 ± 1.79% mortality, S. granarius). Bornyl acetate/cis-chrysanthenyl acetate/hexadecanoic acid and camphor/santolinatriene/ yomogi alcohol chemotypes of C. coronarium are proposed from Cyprus samples according to cluster analysis of the oils together with the literature data.'),(1766,'10.1080/10412905.2017.1420553','Effect of oxygen and heating on aromas of pummelo ( <i>Citrus maxima</i> ) essential oil','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2017.1420553',15,'https://openalex.org/W2783102437','Objective: To investigate effects of oxygen and heating on aromas and volatile components of pummelo essential oil (PEO). Method: The PEOs were analyzed by sensory evaluation, gas chromatography coupled with mass spectrometry (GC-MS), GC-olfactometry (GC-O) and sensory reconstruction analysis. Results: The PEO co-treated by oxygen and heating exhibited significant differences in both aromas and volatile compositions from those of the fresh, the nitrogen-protected, the heated and the oxygen-exposed PEOs. The strong sweet and floral notes of the oxygen and heating co-treated PEO were attributed to high concentration of limonene oxides; the strong minty note was resulted from the increase of L-carvone. Conclusion: The results indicate that limonene oxides and L-carvone could significantly change the aroma of PEO co-treatment by oxygen and heating, providing valuable information for the production and storage of aromatic products of PEO.'),(1767,'10.1080/10412905.2017.1420554','Characterization of essential oils and hydrosols from senegalese <i>Eucalyptus camaldulensis</i> Dehnh','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2017.1420554',18,'https://openalex.org/W2781569228','The volatile oils of Eucalyptus camaldulensis leaves harvested in three agro-ecological areas in Senegal were analysed by GC-FID and GC-MS. The yields ranged from 0.5 to 1.0%. Qualitative and quantitative differences were determined in the composition according to leave sources. The main compounds of Saint-Louis oils were: 1,8-cineole (69.3â73.0%) and limonene (12.4â13.5%), whereas those from Kaolack were characterized by p-cymene (28.4â32.6%), 1,8-cineole (16.8â20.0%), α-pinene (8.7â11.6%) and limonene (7.8â8.3%), while those plants from Dakar revealed high content of β-pinene (25.3â34.4%) and α-eudesmol (12.3â20.6%). During drying of leaves, the proportions of all major compounds (except limonene) increased and were optimal after 2 h hydrodistillation. As in oils, 1,8-cineole was the major compound in hydrosols from Saint-Louis and Kaolack (77.3% and 39.0%, respectively), Dakar floral water showed: α-terpineol (20.3%), 1,8-cineole (12.6%), trans-pinocarveol (9.9%) and α-eudesmol (9.8%) as major compounds. E. camaldulensis from Saint-Louis is a source of essential oils that could be used in pharmaceutical and cosmetic applications.'),(1768,'10.1080/10412905.2017.1422810','Chemical composition of leaf oil from <i>Polyalthia longifolia</i> (Sonnerat) Thwait. grown in Côte dâIvoire','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2017.1422810',4,'https://openalex.org/W2782960912','The chemical composition of 35 leaf oil samples from Polyalthia longifolia (Sonnerat) Thwait., growing in five districts in Abidjan and its suburbs, has been investigated by GC(FID) in combination with retention indices, GCâMS and 13C-NMR. In total, 30 individual components have been identified, mostly sesquiterpenes. The contents of the main components varied substantially from sample to sample: (E)-β-caryophyllene (18.9â31.4%), α-zingiberene (6.1â22.1%), allo-aromadendrene (12.4â17.3%) and α-humulene (6.4â11.0%). However, PCA was unable to differentiate groups within the 35 compositions. The chemical composition of Ivorian P. longifolia leaf oils may be summarized as follow: (E)-β-caryophyllene (M = 25.3%; SD = 1.2), allo-aromadendrene (M = 15.2%; SD = 0.5), α-zingiberene (M = 13.6%; SD = 3.6) and α-humulene (M = 8.4%; SD = 0.2).'),(1769,'10.1080/10412905.2017.1423406','Chemical composition of <i><i>Piper gaudichaudianum</i></i> essential oil and its bioactivity against <i><i>Lucilia cuprina</i></i> (Diptera: Calliphoridae)','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2017.1423406',18,'https://openalex.org/W2783338725','Piper gaudichaudianum grows abundantly throughout the Brazilian Atlantic Forest. Essential oil extracted from this species has been reported to have larvicidal properties. The aim of the study was to characterize the essential oil (EO) of P. gaudichaudianum and its insecticide activity on the third instar larvae (L3) of Lucilia cuprina under laboratory conditions. Groups of 20 L3 were placed on filter paper impregnated with increasing concentrations of 2.5â30% (v/v), equivalent to 0.39â4.77 μL/cm2, solubilized in ethanol or acetone. The toxicity was determined by L3 mortality after 6, 24 and 48 h after contact. P. gaudichaudianum EO was also characterized using CG/MS. Lethal concentrations of 50% (LC50) 24 and 48 h after EO exposure were found to be 3.69 and 2.19 when solubilized in ethanol and 9.14 and 6.05 μL/cm2 when solubilized in acetone, respectively. The major compounds were germacrene B, δ-cadinene, γ-elemene, (Z)-cariophyllene, α-copaene, (E)-cariophyllene, α-calacorene, α-humulene and (E)-nerolidol. The study demonstrated the significant biological activities of P. gaudichaudianum EO (PGEO) compounds against L. cuprina.'),(1770,'10.1080/10412905.2018.1427636','<i>Ligularia amplexicaulis</i> (wall.) DC. Essential oil composition and antibacterial activity','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1427636',7,'https://openalex.org/W2790604294','The essential oil samples from the aerial parts of Ligularia amplexicaulis (wall.) DC. growing wild in the Himalayan region of Uttarakhand, India were isolated by steam distillation and analysed by capillary GC-FID and GC/MS. The oil samples were extracted and analysed separately from the plant material collected from two different locations (Tungnath and Munsiyari, Uttarakhand, India). The oil samples showed quantitative variation with respect to major constituents. Both the oil samples were rich in monoterpene hydrocarbons (67.3 and 82.4%, respectively). Total 47 compounds were identified with limonene (34.0 and 22.0%), p-cymen-8-ol (16.0 and 8.0%), α-pinene (12.0 and 10.0%) and p-cymene (9.0 and 37.0%), respectively, as the major constituents. The oil showed significant antibacterial activity against Gram-negative bacteria Escherichia coli, Agrobacterium tumefaciens, Klebsiella pneumoniae, Xanthomonas phaseoli, Salmonella enteric enterica and Gram-positive Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis. Minimum inhibitory concentration value (31.25 μL/mL) was observed against B. subtilis, S. aureus, E. faecalis, E. coli, A. tumefaciens and P. multocida.'),(1771,'10.1080/10412905.2018.1427637','Seasonal variation in<i>Juniperus polycarpos</i>var.<i>turcomanica</i>essential oil from northeast of Iran','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1427637',16,'https://openalex.org/W2789053773','The composition of hydro-distilled essential oils from fresh leaves of wild growing Juniperus polycarpos var. turcomanica, collected from northeaste of Iran, were investigated by GC and GCâMS analysis during growing season 2012â2013. The oil yields depend on the month of collecting and ranged between 1.5 and 2.1% (v/w). Analysis of the essential oil identified 49 components that representing 89.7â94.6% of the total oil. Results indicated that the predominant presence of monoterpene constituents, representing 56.9â85.6% of the essential oil. The main constituent was α-pinene (41.8â75.4%), followed by germacrene B (1â5.8%), camphor (0.7â4.5%) and α-cadinol (0.4â4.8%). Regarding essential oil composition, quantitative and qualitative variations were recorded for 12 different collection periods. The best time for harvesting juniper leaves seems to be from mid-autumn to mid-winter.'),(1772,'10.1080/10412905.2018.1429327','Chemical composition and antibacterial activity of<i>p</i>-menthane chemotype of<i>Cymbopogon martini</i>(Roxb.) W. Watson (Poaceae) from India','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1429327',19,'https://openalex.org/W2792485976','In this study, the essential oil composition and antibacterial activity of an underexplored population of Cymbopogon martinii (Roxb.) W. Watson was investigated using GCâFID, GCâMS, disc diffusion and micro dilution broth assay. To substantiate the stability of the essential oil profile, the population was grown in the experimental field and its oil was analysed at different growth stages. Altogether, forty-eight constituents, comprising 91.5â96.8% of the total oil composition were identified. Main constituents of the oil were trans-p-mentha-2,8-dien-1-ol (16.6â22.8%), cis-p-mentha-2,8-dien-1-ol (7.2â9.7%), trans-p-mentha-1(7),8-dien-2-ol (9.8â15.8%), cis-p-mentha-1(7),8-dien-2-ol (11.3â18.0%), limonene (10.5â34.8%), isopiperitenol (3.1â5.0%), trans-carveol (3.5â4.5%) and carvone (2.6â3.6%). The oil exhibited wide spectrum, moderate to very good activity against pathogenic bacterial strains (zone of growth inhibition: 9â25 mm; minimum inhibitory concentration, MIC: 125â500 μg/mL). In conclusion, due to high percentage of monoterpene alcohols, the examined oil demonstrated potent antibacterial activity against both Gram-positive and Gram-negative strains.'),(1773,'10.1080/10412905.2018.1433084','Changes in fatty acid profile and oxidation indices of soybean oil supplemented with<i>Ocimum sanctum</i>essential oil during accelerated storage','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1433084',13,'https://openalex.org/W2791805135','The objective of this study was to evaluate the antioxidant activity of different concentrations (250, 500 and 750 ppm) of Ocimum sanctum essential oil incorporated into soybean oil. The effect of O. sanctum essential oil at 250 ppm was similar to that of BHA on inhibiting oxidation in the soybean oil, but higher concentrations of essential oil (500 and 750 ppm) showed higher protection against oxidation in comparison with that of BHA. The influence of O. sanctum essential oil on stabilizing the soybean oil was more profound at 45 °C in comparison with 60 °C. In addition, the O. sanctum essential oil was significantly effective in protecting polyunsaturated fatty acids of soybean oil during storage at both temperatures of 45 and 60 °C. Generally, the O. sanctum essential oil can be introduced as a suitable natural antioxidant that can replace synthetic antioxidants.'),(1774,'10.1080/10412905.2018.1435426','Variability in essential oil composition of different plant parts of<i>Heracleum candicans</i>Wall. Ex DC from North India','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1435426',3,'https://openalex.org/W2792805298','The essential oil composition of different plant parts (leaf, stem, roots and fresh umbels at full bloom, green seed stage and brown seed stage) of H. candicans from North India were studied and compared using GC-FID and GC-MS. Altogether, 49 constituents comprising 85.4â96.2% were identified. α-Pinene (5.4â17.7%), myrcene (0.5â9.7%), α-humulene (5.6â9.5%), lavandulyl acetate (3.2â8.0%), α-copaene (2.4â6.2%), β-pinene (2.1â5.2%) and ar-curcumene (1.8â5.1%) were the major constituents of leaf and stem essential oils of H. candicans. The root essential oil of H. candicans was found to be dominated by α-pinene (40.4%) and β-pinene (15.4%). However, umbel essential oils of different maturity stages of H. candicans were found to be dominated by esters viz. lavandulyl acetate (26.3â40.4%), bornyl acetate (â¤0.05â16.4%) and n-octyl acetate (â¤0.05â10.2%). The essential oil compositions were compared with earlier reports on Heracleum spp. which revealed significant variation in composition. This is for the first time the essential oil composition of different plant parts of H. candicans have been reported from Indian origin.'),(1775,'10.1080/10412905.2018.1435428','Physicochemical characterization and bioactivity evaluation of essential oils from <i>Citrus microcarpa</i> Bunge leaf and flower','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1435428',21,'https://openalex.org/W2791780123','Content of essential oils in flower and leaf of Citrus microcarpa was 1.1 and 0.8% (v/w), respectively. The flower oil was dominated by monoterpene hydrocarbons in which limonene (74.5%) was determined as a major component. The dominant constituents found in the calamondin leaf oil were sesquiterpene (82.0%) with elemol (37.5%) as a major component. The obtained thermal data showed that thermal stability of flower and leaf oils was up to 80 and 110 °C, respectively. A study of TG isothermal volatilization at 42.5 °C showed the mass loss of the essential oils as a function of exposition time. Antioxidant assays using both DPPH and ABTS radical scavenging methods exhibited antioxidant activity of flower and leaf essential oils was higher than that of vitamin C. The leaf essential oil exhibited inhibitory effects against six microbial strains while the flower oil inhibited only one fungus strain, A. niger.'),(1776,'10.1080/10412905.2018.1487343','Antimicrobial activity of some essential oils against<i>Streptococcus agalactiae</i>, an important pathogen for fish farming in Brazil','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1487343',16,'https://openalex.org/W2886880633','The antimicrobial activity of the essential oils from Lippia alba, Lippia sidoides, Mentha piperita, Ocimum gratissimum and Zingiber officinale was tested against Streptococcus agalactiae. The major compounds in the oils, identified by gas chromatography and mass spectrometry (GC/MS), were geranial (25.4%), neral (16.6%) and caryophyllene oxide (16.0%) in L. alba; thymol (76.6%), p-cymene (6.3%) and β-caryophyllene (5.0%) in L. sidoides; menthol (30.5%), menthyl acetate (14.6%), pulegone (14.2%) and menthone (12.9%) in M. piperita; eugenol (43.3%), 1,8-cineole (28.2%) and β-selinene (5.5%) in O. gratissimum; and geranial (23.2%), neral (16.7%) and 1,8-cineole (15.8%) in Z. officinale. All essential oils evaluated showed bactericidal action against S. agalactiae with minimum inhibitory concentration (MIC) ranging from 312.5â2,500 μg mLâ1 and minimum bactericidal concentration (MBC) ranging from 416.7â2,500 μg mLâ1. In this study, L. sidoides essential oil showed the better results against S. agalactiae.'),(1777,'10.1080/10412905.2018.1495108','Aroma volatiles components of âFuerteâ Avocado (<i>Persea americana</i>Mill.) stored under different modified atmospheric conditions','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1495108',11,'https://openalex.org/W2886430713','Modified atmosphere (MA) storage have direct influence on biogenesis and releasing of aroma volatiles in the ripe fruits. A study was conducted to investigate the influence of MA storage on the volatile constituents of ripe avocados. Mature avocados (cv. Fuerte) were packed in four different packaging materials and the equilibrium gas composition developed within the packs were in perforated polyvinylchloride: SM-60 (Control: 20.8% O2 + 0.03% CO2), Micro-porous polypropylene: MY-15 (4.8% O2 + 8.4% CO2), Low density polyethylene: LPDE (7.7% O2 + 5.8% CO2) and Micro-porous polypropylene: MD-15 (9% O2 + 5.4% CO2). The MA packs of avocados were stored at 7°C for 4 weeks and were ripen at 20°C. The volatile compounds of ripe avocados were investigated by means of gas chromatography (GC) and GC-mass spectrometry. A total of 68 of components were identified among those butyl acetate, 3-hexenyl acetate, 2-hexenyl acetate and hexyl acetate were only detected from MA stored avocados. Therefore, the MA storage with suitable gas composition could be used as a novel technology to extend the shelf life without significantly (p > 0.05) affecting the volatile components of the avocados.'),(1778,'10.1080/10412905.2018.1496857','Volatiles profiling and bioactivities of <i>Cupressus</i> spp. leaf and cone essential oils as analyzed via chemometrics tools','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1496857',7,'https://openalex.org/W2885693630','Cupressus is a genus of considerable medicinal value worldwide. The present work aims at assessing essential oil compositional differences within Cupressus in the context of its different genotypes and organs. Volatiles profiling was determined via gas chromatography-mass spectrometry coupled to chemometrics. A total of 75 volatile components were identified. Monoterpene hydrocarbons amounted for the major volatile class, with α-pinene and 3-carene most abundant in Cupressus sempervirens versus sabinene and terpinen-4-ol in Cupressus macrocarpa. Multivariate data analyses revealed that α-pinene, sabinene, terpinen-4-ol and 3-carene are the most significant for species classification. The five examined essential oils exhibited potential insecticidal and anticholinesterase effects, with C. sempervirens var. pyramidalis cone oil being the most potent for acetylcholinesterase inhibitory effect. The oil also exhibited potential fumigant toxicity toward Sitophilus oryzae and Tribolium castaneum. The results of the orthogonal partial least-square discriminant analysis revealed that α-pinene is the key bioactive component in Cupressus oil.'),(1779,'10.1080/10412905.2018.1500315','Essential oils from <i>Tithonia diversifolia</i> display potent anti-oedematogenic effects and inhibit acid production by cariogenic bacteria','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1500315',8,'https://openalex.org/W2883695077','Tithonia diversifolia is an invasive shrub found in the tropical regions. The aim of this study was to investigate the chemical composition as well as anti-inflammatory and antibacterial activities of the essential oils from leaves (EOL) and inflorescences (EOI) of T. diversifolia. The essential oils (EOs) were analysed by gas chromatography with flame ionization detector and coupled with mass spectrometry. EOL and EOI are mainly composed of α-pinene and β-pinene. Both EOL and EOI displayed potent anti-oedematogenic properties at concentrations starting at 0.5 and 2.5% (v/v), respectively. Similar to non-steroidal anti-inflammatory drugs, both EOs inhibited oedema but did not inhibit cellular recruitment. EOI displayed more potent antimicrobial activity against cariogenic microorganisms than EOL. Both EOs significantly inhibited the production of acids by Streptococcus mutans at concentrations that were nontoxic to human gingival fibroblasts (concentrations from 25 to 125 µg/mL for EOL and from 25 to 250 µg/mL for EOI).'),(1780,'10.1080/10412905.2018.1511483','Changes in essential oil composition of<i>Haplophyllum tuberculatum</i>(Forssk.) A. Juss. aerial parts according to the developmental stage of growth and incidence on the biological activities','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1511483',12,'https://openalex.org/W2888936688','Variation in essential oil composition of isolated leaves, isolated stems and leaves + stems of Haplophyllum tuberculatum was studied at the three developmental stages during a one-year phenological cycle. GCâMS analysis showed qualitative and quantitative variation over the phenological cycle. The main components were limonene (7.35â14.34%), α-phellandrene (7.14â11.87%), 2,4-bis(1,1-dimethylethyl)-phenol (2.52â11.56%), trans-p-menth-2-en-1-ol (7.46â10.83%), δ-3-carene (8.33â10.41%), piperitone (2.33â9.42%) and myrcene (4.91â8.25%), where their percentages varied according to the developmental stage of growth. The results from HCA and PCA revealed a clear discrimination between the three studied developmental stages. Essential oils at flowering and fruiting stages showed higher antimicrobial activity than those at vegetative stage. The highest antioxidant activity was also exhibited by essential oils at flowering and fruiting stages. The present findings allowed choosing the best organ with the optimal harvesting period to have the highest effectiveness of essential oil in terms of biological activities.'),(1781,'10.1080/10412905.2018.1512907','Composition and hepatoprotective activity of essential oils from Ethiopian thyme species (<i>Thymus serrulatus</i> and <i>Thymus schimperi</i>)','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1512907',22,'https://openalex.org/W2891512061','The chemical composition of six essential oils (EOs) of Thymus serrulatus and Thymus schimperi from six localities in Ethiopia, namely Ofla, Alamata, Yilmana Densa, Tarmaber, Butajira and Bale was determined. The in vivo hepatoprotective potential of three of the EOs was evaluated. GC-MS and NMR were used to determine chemical composition and GC-FID to quantify the main compounds. The number of EO components ranged from 17 to 41. The EOs were of two chemotypes with either thymol (Ofla, Alamata, Tarmaber and Bale) or carvacrol (Yilmana Densa and Butajira) being the main compound. Hepatoprotection of EOs was tested against paracetamol-induced hepatotoxicity in Wistar albino rats. Hepatoprotective properties of the oils were demonstrated by reduced serum levels of hepatic marker enzymes (AST, ALT and ALP) and normal hepatocytes structure. The most effective one was the thymol type EO from Alamata.'),(1782,'10.1080/10412905.2018.1518275','Essential oil compounds from the leaf of <i>Eugenia samanensis</i> Alain (Myrtaceae), a species endemic to the Samaná Peninsula, Dominican Republic','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1518275',12,'https://openalex.org/W2890282847','Eugenia samanensis Alain is an endangered species of Myrtaceae unique to the Samaná Peninsula, Dominican Republic. We investigated its foliar essential oil (EO) composition from dried leaves, extracted via hydrodistillation, by gas chromatography-mass spectrometry (GC-MS) for identification and gas chromatography-flame ionization detection (GC-FID) for quantification. E. samanensis leaves produced an average of 1.6 ± 0.1% (w/w) EO and 23 compounds were identified, representing 98.4% of the EO composition. The EO composition consisted of 84.4% phenylpropenes, 8.9% oxygenated monoterpenes, 4.0% oxygenated sesquiterpenes, 0.4 % monoterpenes, 0.4% sesquiterpenes, and 0.25% other. The EO was richest in the phenylpropene, methyleugenol. The abundance of phenylpropenes in the EO of E. samanensis may be unique to Eugenia, suggesting the need for further research to elucidate the biological function of these compounds, to review the taxonomic status of this species, and to perform further studies to explain the high phenylpropene content of this species.'),(1783,'10.1080/10412905.2018.1518794','Biomass production and essential oil composition of <i>Thymus vulgaris</i> in response to water stress and harvest time','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1518794',28,'https://openalex.org/W2892804310','A greenhouse experiment was conducted to study the effects of irrigation interval (4, 8, 12 and 16 days) and harvest (2, 4, 6, 8, 10 and 12 months after transplanting) on biomass, essential oil (EO) content and composition of Thymus vulgaris. As irrigation interval increased, herb fresh and EO yield decreased, but EO content increased, suggesting water stress stimulates EO content. While fresh weight peaked at 4 months, EO content and yield peaked at 6 months; then they declined and reached the bottom at 12 months. Thymol, p-cymene and γ-terpinene were the major compounds in T. vulgaris. The highest γ-terpinene and p-cymene were obtained when harvested at 12 months. The highest thymol was obtained when harvested at 2 months and irrigated every 4 days. This study showed biomass, EO content, yield and the accumulation of EO constituents of T. vulgaris are influenced by irrigation interval and harvest in different ways.'),(1784,'10.1080/10412905.2018.1519465','Antioxidant and antifungal activities of the flowersâ essential oil of<i>Tagetes minuta</i>, (<i>Z</i>)-tagetone and thiotagetone','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1519465',17,'https://openalex.org/W2893258366','Herein, we describe our results on the determination of the chemical profile of the essential oil (EO) of flowers from Tagetes minuta L. grown in Southern Brazil. The major component of the EO is (Z)-tagetone 1 (70.64% w/w). Thiotagetone 6, a semi-synthetic derivative, was prepared from 1 in 82% yield. Compounds 1 and 6 and the EO were evaluated for their antioxidant and antifungal activities in vitro. All the tested samples presented antioxidant effect in scavenging radical and in the lipid peroxidation assays. A good antifungal activity against Candida lipolityca, Candida parapsilosis, Trichosporon asahii and Sphaceloma ampelinum was observed. (Z)-Tagetone 1 inhibited the mycelia growth of S. ampelinum around 80% at 6 days. No acute toxicity (200 mg/kg) was observed in mice for the EO or the compounds 1 and 6. The lack of toxicity is an indicative for additional studies aiming their potential therapeutic use.'),(1785,'10.1080/10412905.2018.1539415','Regional effect on essential oil composition and antimicrobial activity of <i>Thymus capitatus</i> L.','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1539415',34,'https://openalex.org/W2898826140','A biochemical characterization and a geographic variability of Thymus capitatus L. essential oils were undertaken. Chromatographic analysis using gas chromatography-ï¬ame ionization detector and gas chromatography-mass spectrometry of essential oils extracted from thyme aerial parts from four Tunisian regions (Kef, Bizerte, Boukornine and Grombalia) showed the predominance of carvacrol (75.79 ± 2.07%) in Boukornine region, thyme essential oils being carvacrol chemotype. Obtained results of antimicrobial activities showed that thyme essential oil has important antibacterial activity which was strongly related to the organoleptic quality of the oil which appeared strongly region-dependent. The inhibitory effect of thyme essential oils on the bacteria and fungi development showed that Bacillus cereus and Fusarium solani were the most sensitive bacteria and fungi, respectively. From these results, we have concluded that thyme essential oil could be used to cure mycotic infections and may have role as pharmaceutical and preservative agents.'),(1786,'10.1080/10412905.2018.1539416','Promising antifungal activity of <i>Croton tricolor</i> stem essential oil against <i>Candida</i> yeasts','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1539416',11,'https://openalex.org/W2899399588','The aim of this research was to determine the phytoconstituents of the essential oil (EO) obtained from stems of Croton tricolor and to study its antifungal activity against several Candida species. The EO was extracted from C. tricolor stems by hydrodistillation with a Clevenger apparatus. This EO was characterized by four major components: epiglobulol, α-bisabolol, α-trans-bergamotol and β-caryophyllene. Microbiological assays were performed using the microdilution method in liquid medium to determine the minimum inhibitory concentration (MIC) for each Candida strain. EO concentrations from 1.0 to 1024 μg/mL inhibited the growth of all tested strains. Overall, the microbiological assays showed that C. tricolor EO has significant inhibitory activity against several Candida species. Thus, the C. tricolor stem EO is a promising natural product in the treatment of candidiasis.'),(1787,'10.1080/10412905.2018.1540364','FT-IR and GC-MS analyses of an antioxidant leaf essential oil from sage plants cultivated as an alternative to tobacco production','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1540364',12,'https://openalex.org/W2899039380','The renewed interest in medicinal and aromatic plants and the increase in their market demand have favoured rural development programs for their cultivation, also as a measure to counteract the profound crisis affecting some agricultural sectors. Sage (Salvia officinalis) is a plant of the Lamiaceae family, whose leaves contain some different active ingredients, which confer sage-based preparations any properties. In particular, sage essential oil (EO) is known for its antiseptic and balsamic properties.As the composition of sage EO strongly depends on environmental factors, the chemical investigation of a leaf EO, obtained from sage plants experimentally cultivated in the Benevento area (Campania, Italy), was achieved using analytical techniques as Fourier Transform Infrared Spectroscopy (FTIR) and Gas Chromatography coupled to Mass Spectrometry (GC-MS) and flame ionization detector (FID). Furthermore, in order to strengthen potential uses of products based on locally cultivated sage, different assays were performed to evaluate its antioxidant effects.'),(1788,'10.1080/10412905.2018.1545706','Essential oil composition of leaves and inflorescences of<i>Elsholtzia densa</i>Benth. from western Himalaya','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1545706',12,'https://openalex.org/W2901315410','The essential oil compositions of leaves and inflorescences of Elsholtzia densa Benth. from western Himalaya were studied and compared using gas chromatography-flame ionization detector and gas chromatography-mass spectrometry. Altogether, forty constituents comprising 83.3â83.7% of essential oil composition were identified. The leaf essential oil of E. densa was characterized by citral (52.2%), geranyl acetate (3.3%) and geraniol (3.1%), whereas the inflorescence essential oil of E. densa was found to be dominated by pinocarvone (51.9%), cis-pinocamphone (5.2%) and citronellyl acetate (3.4%). The essential oil compositions were compared with earlier reports on Elsholtzia spp. from different geographic regions that revealed noteworthy compositional variability.'),(1789,'10.1080/10412905.2018.1547226','Glandular trichome structures and chemical composition of the volatiles of five<i>Ribes</i>species from Turkey','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1547226',7,'https://openalex.org/W2901626943','Currant and gooseberry, the genus Ribes, is represented by eight species in the Flora of Turkey. We examined structures of glandular trichomes and composition of the essential oils from leaves of five Ribes species. The glandular trichomes were investigated by light and scanning electron microscopy. The glandular hairs with multicellular stalk and usually multicellular head were observed in these species. The leaf volatiles of Ribes species obtained by hydrodistillation were analyzed by GC-FID (gas chromatography - flame ionization detector) and gas chromatographyâmass spectrometry techniques. The main constituent of Ribes orientale, Ribes alpinum, Ribes petraeum and Ribes rubrum oils was 1-octen-3-ol (28.1%, 19.7%, 13.3%, and 9.4%, respectively). Hexadecanoic acid (13.8% and 11.9%) was detected in R. petraeum and R. multiflorum as major component, respectively. (Z)-3-hexenal (11.7%) was found in R. rubrum oil as the major constituent.'),(1790,'10.1080/10412905.2018.1550021','Comparative evaluation of Tunisian <i>Mentha</i> L. species essential oils: selection of potential antioxidant and antimicrobial agents','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1550021',11,'https://openalex.org/W2902309601','Essential oils of M. pulegium L., M. rotundifolia L., M. longifolia L. and M. spicata L. were assessed for their antioxidant and antimicrobial activities. M. rotundifolia was distinguished by high amounts of rotundifolone (42.6%), while the main compound in M. pulegium was pulegone (66.1%). The dominant compounds in M. longifolia oil were pulegone (29.3%) and iso-menthone (25.5%). Carvone (58.7%) was the main constituent of M. spicata. Essential oils of M. longifolia and M. spicata showed the best DPPH activity. M. rotundifolia and M. longifolia exhibited the highest FRAP, and iron-chelating activity. M. pulegiumâs essential oil exhibited the best antibacterial activity. The highest antifungal activity was observed for M. rotundifolia. The variation of the biological activities among species was linked to that of their essential oil composition. The spontaneous species M. pulegium and M. rotundifolia revealing attractive chemotypes and biological activities may be included in Tunisian national mint culture programs.'),(1791,'10.1080/10412905.2018.1555102','Influence of diurnal variation in the chemical composition and bioactivities of the essential oil from fresh and dried leaves of<i>Lantana camara</i>','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2018.1555102',14,'https://openalex.org/W2911146972','Lantana camara species is generally seen only as a detriment to plantations but it also possess medicinal potential. This work aimed to analyse the essential oil (EO) yield and chemical composition of fresh and dry leaves versus seasonal variation of L. camara, as well as its inhibition of fungi, bacteria and towards the enzyme acetylcholinesterase. Variations in EO yield and its chemical composition in front of the aforementioned variations were found to be notorious. EO obtained from fresh and dry leaves throughout the day (6am, 12pm and 6pm) presented inhibition of Candida albicans higher than the standards. However, what is clear is that the EO from dry leaves of L. camara were the best inhibitors of fungi, bacteria and also of AChE, this latter standing out by a potent inhibition reaching 96.10%, superior to the standard used (90.31%).'),(1792,'10.1080/10412905.2018.1556745','Evaluation of the carbon isotope ratios of selected volatiles determined in several citrus authentic petitgrain oils. Bigarade (<i>C. aurantium</i>) petitgrain oilâs first case report','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1556745',2,'https://openalex.org/W2906415631','Selected volatile components were analyzed by gas chromatography (GC) coupled to a combustion-isotope ratio mass spectrometer to assess their δ13C values in authentic citrus leaf oils. In particular were analyzed lemon, mandarin and bitter orange petitgrain oils industrially produced by a local factory. All the samples were then analyzed by gas chromatography mass spectrometry and gas chromatography-flame ionization detection and enantio-GC for the quality assessment of each petitgrain. These values were then compared and genuineness of each sample was defined based on all the different parameters detected. The results show good agreement between the different analytical approaches. In addition in this article are reported for the first time the δ13C values relative to genuine bitter orange petitgrain oil, useful for the quality assessment of this niche product of great economical importance.'),(1793,'10.1080/10412905.2018.1563569','Allelopathic effect of endemic South American<i>Bothriochloa</i>species (Poaceae: Andropogoneae)','Journal of Essential Oil Research',2018,'https://doi.org/10.1080/10412905.2018.1563569',5,'https://openalex.org/W2907920824','The essential oil composition of Bothriochloa velutina has been studied. The principal compounds of essential oils of three South American endemics, B. eurylemma, B. meridionalis and B. velutina were isolated. In laboratory bioassays, the principal compounds inhibited the seed germination and root and shoot growth of lettuce (Lactuca sativa L.), maize (Zea mays L.), wintergreen paspalum (Paspalum guenoarum Arechav.) and lovegrass [Eragrostis curvula (Schard.) Nees] test species. The aqueous extracts from different plant parts of three species of Bothriochloa inhibited the seed germination and root and shoot growth of test species. Aqueous extracts were more inhibitory to shoot and root elongation than to seed germination. Significant inhibition in shoot length at all concentrations indicated the phytotoxic activity of extracts. The toxicity enhanced with increasing aqueous extract concentrations. The compounds isolated can interfere with seed germination and seedling growth of plants. Consequently, the study of these chemical interactions might be useful to develop new classes of environmentally safe herbicides.'),(1794,'10.1080/10412905.2018.1564381','Chemical composition and antioxidant activity of<i>Bursera graveolens</i>(Kunth) Triana<i>et</i>Planch essential oil from Manabí, Ecuador','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2018.1564381',12,'https://openalex.org/W2906738822','The chemical composition and antioxidant activity of the essential oil from the stems of Bursera graveolens (Kunth) Triana et Planch grown in Manabí (Ecuador) were studied. Ninety-nine compounds were identified in the essential oil. Monoterpene hydrocarbons and oxygenated monoterpenes were the most represented classes of volatiles with 35.4% and 30.4%, respectively. The main constituents of the oil were limonene (34.9%) and α-terpineol (13.4%). Antioxidant activity were examined using 1,1-diphenyl-2-picryl-hydrazyl assay and the ferric-reducing antioxidant power assays. The essential oil had a moderate scavenging effect and it showed ferric reducing activity. These results validate the use of this plant in the traditional medicine.'),(1795,'10.1080/10412905.2019.1566099','Essential oil composition of leaves and flowers of two endemic <i>Phlomis</i> L. species (<i>Phlomis cypria</i> post and <i>Phlomis brevibracteata</i> Turrill) from Northern Cyprus','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1566099',3,'https://openalex.org/W2910101136','Essential oils of the leaves and flowers of Phlomis cypria and P. brevibracteata were isolated by hydrodistillation and analysed by GC and Gas chromatography - mass spectroscopy (GC-MS), simultaneously. Essential oil yields of the four samples ranged between 0.07% and 0.09% (v/w). The essential oils of leaves (L) and flowers (F) of P. brevibracteata were found to be rich in β-caryophyllene (L: 21.9%, F: 24.2%) and caryophyllene oxide (L: 26.0%, F: 7.2%). Main constituents of the essential oils of P. cypria leaves (L) and flowers (F) were determined as β-caryophyllene (L: 37.4%, F: 20.8%) and germacrene D (L: 47.7%, F: 17.2%).'),(1796,'10.1080/10412905.2019.1566100','Chemical composition of leaves, inflorescence, whole aerial-parts and root essential oils of patchouli { <i>Pogostemon cablin</i> (Blanco) Benth.}','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1566100',35,'https://openalex.org/W2911561563','The essential oils extracted from the leaves, inflorescence, whole aerial-parts and root of patchouli [Pogostemon cablin (Blanco) Benth.] were analyzed and compared using GC-FID and GC-MS. Altogether thirty-four constituents, representing 86.9â97.7% of the total oil compositions, were identified. Major constituents of the oils of aerial-parts (leaves, inflorescence and whole aerial-parts) were patchouli alcohol (42.2â57.7%), α-bulnesene (9.0â15.2%), α-guaiene (6.4â17.9%), seychellene (3.4â6.9%), pogostol (0.3â5.0%) and (E)-caryophyllene (2.1â3.6%). However, the root oil was characterized by higher amount of pogostone (70.2%), norpatchoulenol (5.3%) and β-pinene (4.5%).'),(1797,'10.1080/10412905.2019.1567399','Chemical composition of endemic <i>Stachys subnuda</i> Montbret &amp; Aucher ex Benth. essential oil and its anti-inflammatory and antioxidant activities','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1567399',7,'https://openalex.org/W2946104971','The essential oil of aerial parts of Stachys subnuda Montbret & Aucher ex Benth (S. subnuda) was analyzed by gas chromatography (GC) and GC/mass spectrometry (MS). Anti-inflammatory activity was evaluated by lipoxygenase inhibition assay. The antioxidant activity was determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2â-azinobis-3-ethylbenzothiozoline-6-sulfonic acid (ABTS) assays. Sixty-two constituents, comprising 97.1% of the total essential oil composition, were identified. Phytol (25.2%), β-caryophyllene (11.2%), germacrene D (6.9%), and hexadecanoic acid (6.9%) were the major compounds of aerial part essential oils of S. subnuda. The essential oil showed significant radical scavenging activity with 50% inhibition (IC50) values of 0.124 and 0.204 mg/mL for ABTS and DPPH radicals, respectively. The essential oil exhibited moderate anti-inflammatory activity with an IC50 value of 0.419 mg/mL. The results indicated that S. subnuda essential oil had good anti-inflammatory and antioxidant activity. Also, this is first study on chemical composition, anti-inflammatory and antioxidant activity of S. subnuda essential oil.'),(1798,'10.1080/10412905.2019.1567400','Chemical composition and herbicidal activity of essential oils from two Labiatae species from Algeria','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1567400',30,'https://openalex.org/W2911792927','The aim of the present study was the evaluation of the phytotoxic effect of essential oils (EOs) from two Labiatae species, namely Thymus fontanesii Boiss. et Reut. and Satureja calamintha subsp. nepeta Briq. on some of the most harmful weeds in Algeria (Sinapis arvensis L., Avena fatua L., Sonchus oleraceus L., Xanthium strumarium L. and Cyperus rotundus L.). EOs isolated by hydrodistilation were analyzed by gas chromatography-flame ionization detector (GCâFID) and GC-mass spectrometry (MS). Carvacrol (52.1%), thymol (13.3%), p-cymene (12.2%) and γ-terpinene (8.1%) were the dominant compounds in T. fontanesii EO, while 1,8-cineole (28.4%), pulegone (10.2%), menthone (9.7%) and isomenthone (9.6%) were the most important constituents of S. calamintha EO. The bio-assessments showed a wide herbicidal effect on seed germination (EOs at 0.01, 0.02 and 0.03%) and 3â4 leaf stage weeds (EOs at 1, 2 and 3%) due to the disruption of their physiological process. Based on our results, it can be concluded that the EOs could be exploited for weed biocontrol.'),(1799,'10.1080/10412905.2019.1569564','Extraction process of the <i>Achyrocline satureioides</i> (Lam) DC. essential oil by steam distillation: modeling, aromatic potential and fractionation','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1569564',17,'https://openalex.org/W2915867838','The essential oil of Achyrocline satureioides was obtained by steam distillation in four operating conditions (1.0, 1.5, 2.0 and 2.5 bar) and the aromatic profile of these essential oils was evaluated by gas chromatography/olfactometry (CG/O). It was observed that the relation between the aromatic intensities and the compounds concentration is not directly proportional, except for the α-pinene, which presented a high concentration and aromatic intensity. The essential oil compounds were identified by gas chromatography/mass spectrometry and a principal component analysis (PCA) was used to evaluate the pressure effect on the essential oil composition. Through the PCA, similarity of composition was observed between pressures of 2.0 and 2.5 bar. Furthermore, a mathematical modeling of extraction process and an essential oil theoretical fractionation process study by batch distillation of the major compounds were performed. In order to enhance its aromatic activity, the simulation methodology applied to fractionate the A. satureioides essential oil presented a high-purity (99.10%) α-pinene fraction.'),(1800,'10.1080/10412905.2019.1572549','Chemical composition and biological activity of essential oils from <i>Artemisia copa</i> Phil. var. copa (Asteraceae) and <i>Aloysia deserticola</i> (Phil.) Lu-Irving &amp; OâLeary (Verbenaceae), used in the Chilean Atacamaâs Taira Community (Antofagasta, Chile)','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1572549',6,'https://openalex.org/W2914052938','Two aromatic species from the Atacama people traditional medicine, Aloysia deserticola (Phil.) Lu-Irving & OâLeary and Artemisia copa Phil. var. copa, from Antofagasta area (North of Chile) were investigated for their essential oils (EO) chemical composition, antioxidant and antimicrobial activity. EO of A deserticola collected in four different spots unexpectedly contained α-thujone as the major compound instead of the β-isomer described for other Chilean and Bolivian specimens in the literature. For EO of Artemisia copa var. copa, chrysanthenone was the main compound whereas β-thujone was identified in a Bolivian specimen. These EO exerted no significant antibacterial activity on a panel of forty-four strains, whereas notable inhibition of xanthine oxidase activity was observed with A. deserticola essential oil.'),(1801,'10.1080/10412905.2019.1572550','Chemical composition of the essential oils from <i>Helichrysum arenarium</i> (L.) plants growing in Lithuanian forests','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1572550',12,'https://openalex.org/W2914588868','Chemical composition of the essential oils (16 samples) obtained by hydro-distillation from inflorescences and leaves of Helichrysum arenarium L. plants growing in Lithuanian forests is reported. Fifty-six compounds were identified by GCâMS and GC (FID), which made up 80.1â98.8% of total oil content. The main fractions were found to be sesquiterpenes (29.0â70.1%) and aliphatics hydrocarbons (7.7â45.5%) followed by oxygenated monoterpenes (2.0â13.9%). Among terpenoids, the first principal constituents revealed were as follows: 1,8-cineole (8.9%, one sample), β-caryophyllene (5.8â36.2%, 14 oils), and γ- and δ-cadinene (5.8% and 9.0%, respectively). However, the essential oils contained appreciable amounts of aliphatic hydrocarbons (mainly octadecane and heneicosane), whose origin is most probably from epiticular waxes of the plant. The dominant content of octadecane was 7.1â22.3%, while an appreciable quantity of heneicosane varied from 7.9% to 20.0%. The main compositional data were subjected to the statistical analysis. The results obtained clearly demonstrated remarkable differences in chemical composition of the essential oils of Lithuanian H. arenarium L. from the oils of everlastings from other world countries.'),(1802,'10.1080/10412905.2019.1579761','Comparative study of chemical composition of essential oils for two species of <i>Asteriscus</i> genus from Western Algeria','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1579761',5,'https://openalex.org/W2915539062','Comparative study between the chemical composition of the essential oils of Asteriscus maritimus and Asteriscus spinosus from Western Algeria have been investigated. Chemical variability of the essential oils of both species was reported for the first time using gas chromatography/retention indices (GC/RI) and GC-mass spectrometry (GC/MS). A total of 86 compounds were identified in A. maritimus collective essential oil and 76 compounds in A. spinosus collective essential oil. Intra-species variations of the chemical compositions of essential oil from eighteen Algerian samples of various locations of both species were also investigated using statistical analysis. A. maritimus essential oils were characterized by T-cadinol (34.2â16.1%), p-cymene (30â15.1%), α-pinene (13.9â2.8%), bornyl acetate (8.7â5.3%) and Z-phytol (7.8â2.4%), as the major compounds. The main compounds of A. spinosus were α-cadinol (19.8â7.3%), β-pinene (17.6â12.9%), hexadecanoic acid (13.4â4.1%), T-cadinol (10.3â3.5%) and δ-cadinene (8.2â3.9%).'),(1803,'10.1080/10412905.2019.1579762','Essential oil compositions of subspecies of<i>Scutellaria brevibracteata</i>Stapf from Turkey','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1579762',15,'https://openalex.org/W2923180316','The essential oils obtained by hydrodistillation from the aerial parts of three subspecies of Scutellaria brevibracteata (subsp. brevibracteata, subsp. subvelutina and subsp. pannosula) collected from their natural localities in Turkey were analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS), simultaneously. On the basis of chromatographic analysis and data analyzed, β-caryophyllene (22.8%) and caryophyllene oxide (16.0%) were determined as the main components in S. brevibracteata subsp. brevibracteata oil. In S. brevibracteata subsp. subvelutina oil, β-caryophyllene (28.3%), linalool (12.4%) and hexadecanoic acid (10.8%) were found as major constituents. β-Caryophyllene (36.4%), α-cadinol (9.8%), δ-cadinene (7.0%) and linalool (5.3%) were identified as major components in the oil of S. brevibracteata subsp. pannosula. To the best of our knowledge, this is the ï¬rst report on the chemical composition of the essential oils of three subspecies of Scutellaria brevibracteata.'),(1804,'10.1080/10412905.2019.1580225','Acaricidal activity of cashew nut shell liquid associated with essential oils from <i>Cordia verbenacea</i> and <i>Psidium guajava</i> on <i>Rhipicephalus microplus</i>','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1580225',21,'https://openalex.org/W2918011499','The aim of this study was to assess the effectiveness of cashew nut shell liquid (CNSL), Cordia verbenacea and Psidium guajava, both alone and in association against Rhipicephalus microplus. Larval packet and adult immersion tests were conducted in concentrations ranging from 3.1 at 100.0mg mLâ1. CNSL was effective against engorged females (99.6%) at 100.0mg mLâ1 and against larvae (99.2 %) at 50.0mg mLâ1. The highest efficacy on engorged females was achieved by the essential oils of P. guajava at 12.5mg mLâ1 (99.9%), followed by those of C. verbenacea at 25.0mg mLâ1 (96.9%), while a low larvicidal activity of 5.8 and 59.0% was, respectively, obtained. The association at 50.0mg mLâ1 had asignificant effect on both life stages of R. microplus. This association caused considerable larval mortality (95.3%) and high efficacy on engorged females (93.9%).'),(1805,'10.1080/10412905.2019.1583140','Essential oil composition of berries of <i>Juniperus oxycedrus</i> L. ssp. <i>oxycedrus</i> according to their ripening stage','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1583140',5,'https://openalex.org/W2920911693','Some essential oils (EOs) can be extracted from berries of different species, and their composition depends on their maturation level. In this work, these parameters were correlated for Juniperus oxycedrus L ssp. oxycedrus. For this purpose, a classification method based on the CIE L*a*b* colour measurement was applied. Once the samples were classified, they were subjected to simultaneous distillation extraction and gas chromatography (GC/FID and GC/MS). Hydrocarbon monoterpenes constituted the major fraction (42.8â89.8%), mainly represented by α-pinene (30.1â66.4%) and myrcene (6.1â34.8%). Hydrocarbon sesquiterpenes accounted for 4.0â26.4%, with germacrene-D (0.2â16.9%) as the major component. The discriminant analysis proved that CIE L*a*b* implementation was useful to classify the ripening stage. Regarding the EO composition, significant differences were observed in myrcene, camphor and germacrene-D, as well as in the grouped oxygenated and hydrocarbon terpenoids. In general, a progressive increase in oxygenated compounds was noted over the maturation process.'),(1806,'10.1080/10412905.2019.1584591','Chemical composition, antioxidant and antimicrobial activities of essential oils of different <i>Pinus</i> species from Kosovo','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1584591',36,'https://openalex.org/W2911901610','Chemical profile, antioxidant and antimicrobial activity of total and fractionated essential oils (EOs) derived from Pinus heldreichii, P. peuce, P. mugo, Pinus nigra and P. sylvestris, along with the volatiles profile (VOCs) of needles of these species were investigated. The EOs and their fractions (direct solid phase extraction, SPE) were analysed by GC-MS, while VOCs of needles were determined by HS-SPME-GC-MS. 112 compounds were identified in EOs and their fractions. The same trend was observed in the needlesâ VOCs. The EOs antioxidant activities were lower than those of the corresponding fractions, with F2 the strongest in all cases. EOs and fractions showed different degrees of antibacterial efficacy against different microbial pathogens. The components responsible for the antioxidant and antimicrobial activity were oxygenated monoterpenes and sesquiterpenes. These activities seem to be regulated by reciprocal interactions among the different subclasses of phytochemical species present in the EOs.'),(1807,'10.1080/10412905.2019.1593891','Chemical composition and antibacterial activities of essential oil from <i>Ageratina pentlandiana</i> (DC.) R.M. King &amp; H. Rob. leaves grown in the Peruvian Andes','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1593891',10,'https://openalex.org/W2952536366','The chemical composition and antibacterial activity of the essential oil from the leaves of Ageratina pentlandiana (DC.) R.M. King & H. Rob. grown in Cuzco (Peru) was studied. One hundred and fifteen compounds were identified in the essential oil. The essential oil was dominated by phenyl derivative constituents (39.9%), including 2,5-dimethoxy-p-cymene (20.9%), thymol methyl ether (9.9%) and 2,5-dimethoxy-p-cymenene (8.2%) as the most abundant constituents identified in leaves oil. The antibacterial activity was studied by the disk diffusion method and minimal inhibitory concentration and minimal bactericide concentration were determined against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella tiphymurium. The essential oil showed a marked antibacterial activity, especially against S. aureus and B. subtilis.'),(1808,'10.1080/10412905.2019.1606740','Chemical composition and<i>in vitro</i>bioactivity of essential oil obtained from the flavedo of âPompiaâ, an ancient Sardinian fruit','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1606740',14,'https://openalex.org/W2943269097','Pompia (Citrus limon var. pompia) grows in the North-East Sardinia (Italy). This fruit is used in traditional pastries, the flavedo for the preparation of liqueurs by hydroalcoholic infusion. We investigated the chemical composition and bioactivity of the essential oil obtained by hydro-distillation from the peel of pompia (PEO). Gas chromatographic analysis allowed us to determine the PEO chemical composition: the major compound was limonene (LM) (803.8 mg/mL). PEO showed antioxidant activity in the β-carotene/linoleic acid bleaching test and radical-scavenging activity in the DPPH assay. PEO significantly reduced viability in HeLa and B16F10 cancer cells, and its toxic effect was mainly associated with LM cytotoxicity. PEO significantly increased intracellular free radical levels in cancer cells, without affecting the cellular phospholipid composition. The HPLC-DAD analysis of the cancer cell medium after PEO-treatment revealed the presence of perillic acid, a LM metabolite with anticancer activity. Our findings provide new insights for the PEO nutraceutical potential.'),(1809,'10.1080/10412905.2019.1610089','Comparative chemical composition and bioactivity of leaves essential oils from nine Sicilian accessions of <i>Myrtus communis</i> L.','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1610089',21,'https://openalex.org/W2943582612','In this study, the essential oils obtained from the leaves of Myrtus communis L. stored in a collection orchard located at the experimental station âOrleansâ of the Department of Agricultural and Forest Sciences of the University of Palermo (Italy) were investigated. The essential oils, analysed by gas chromatographyâmass spectrometry, revealed the presence of α-pinene, 1,8-cineole, linalool, limonene and myrtenyl acetate as dominant constituents. The neuroprotective effects of M. communis essential oils were investigated by analysing the antioxidant properties and cholinesterases (acetylcholinesterase, AChE, and butyrylcholinesterase, BChE) inhibitory activity. Essential oils from Scopello accession possessed a promising radical scavenging potential with IC50 values of 71.4 and 75.9 μg/mL for EO1 and EO2, respectively. Essential oil from Monte Pellegrino (EO5) showed the highest cholinesterase inhibitory activity with IC50 values of 96.0 and 87.9 μg/mL for AChE and BChE, respectively. Significant result was obtained also with EO1 against the BChE (IC50 of 77.8 μg/mL). Data on essential oil together with antioxidant effects were used as variables to set a matrix for statistical analysis. Results suggest that M. communis leaves EO could be potentially used in pharmaceutical field.'),(1810,'10.1080/10412905.2019.1610516','Effect of the aromatisation with summer savory (<i>Satureja hortensis</i>L.) essential oil on the oxidative and microbial stabilities of liquid whole eggs during storage','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1610516',18,'https://openalex.org/W2942885987','The Algerian essential oil (EO) extracted by hydro-distillation from Satureja hortensis L. (S. hortensis) was characterised by gas chromatographyâmass spectrometry (GC-MS). S. hortensis (summer savory) was chemotype carvacrol (54.2%) and γ-terpinene (21.1%). In its second part, the present study was conducted to evaluate in vitro, antioxidant activity of savory EO using the 2,2-di-phenyl-1-picrilhydrazyl (DPPHâ¢) free radical scavenging assay. Finally, the EO was screened for biological activities in liquid whole eggs (LWE). The ability of savory EO to scavenge the free radical (DPPHâ) was very high, exceeding 80%. The long-term oxidative and microbial stability of LWE was positively influenced by EO treatments, increasing the shelf life to more than eight (> 8) days under refrigeration. Therefore, the results obtained in this work confirm savory EO treatment as a promising technology to extend the commercial shelf life of liquid egg products, as well as to maintain the quality of LWE as ingredient in innovative food products.'),(1811,'10.1080/10412905.2019.1610517','Development of postharvest management practices for quality essential oil production of <i>Cymbopogon flexuosus</i> (Nees ex Steud.) W. Watson','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1610517',5,'https://openalex.org/W2976386495','Cymbopogon flexuosus (Nees ex Steud.) W. Watson, commonly known as lemongrass, is a member of Cymbopogon genus renowned for their highly prized essential oils for flavor and fragrance industries. A field experiment was conducted to standardize the postharvest storage practices for a prevalent high oil yielding cultivar âKrishnaâ of lemongrass during 2014â2015 and 2015â2016 under open field, shade, and ventilated room; up to 10 days after harvest. Results revealed significantly higher essential oil content (1.14%) for freshly distilled herb as compared to stored herbs under different condition.The highest geranial and neral ratio (1.45 to 1.58) recorded in essential oil i.e. distilled at first day of harvest (T1) as compared to 1.37 to 1.44 in essential oil i.e. distilled at 10th day of harvest (T10). In conclusion, C flexuosus should preferably be distilled as fresh i.e. same day of harvest for higher yield of quality essential oil.'),(1812,'10.1080/10412905.2019.1612472','Chemical composition of the leaf oil from<i>Baccharis punctulata</i>DC. at two phenological stages','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1612472',5,'https://openalex.org/W2944570431','Leaf oil of male Baccharis punctulata DC. from Argentina was analyzed at vegetative and at flowering stage. Compound identification and differences are reported. The major component at vegetative stage (42-48%) was identified as the rare furanocadinane verboccidentafuran. 13C-NMR data of verboccidentafuran are assigned for the first time. Other components are δ-elemene (9.1%), β-elemene (3.1%), amorpha-4,7(11)-diene (7.5%), β-bisabolene (2.4%), δ-cadinene (2.5%), cis-cadin-4-en-7α-ol (5.0%), α-muurolol (2.8%), α-cadinol (2.0%) and α-bisabolol (2.7%). At flowering stage, oils showed two major components: verboccidentafuran (22.4%) and the infrequent germacra-1(10),5-dien-4α-ol (17.3%) which was unambiguously differentiated from the 4β-ol diastereoisomer. Other components are (E)-β-ocimene (2.4%), linalool (2.5%), δ-elemene (8.6%), β-elemene (3.3%), amorpha-4,7(11)-diene (2.3%), elemol (2.6%), guaiol (2.4%), cis-cadin-4-en-7α-ol (6.4%), α-muurolol (3.4%) and α-bisabolol (2.3%). Female plant leaf oils showed similar tendency. All oils were sesquiterpene-rich. Different composition is associated with flowering. Major compounds are reported in B. punctulata for the first time.'),(1813,'10.1080/10412905.2019.1612789','Chemical composition, antibacterial and antioxidant activities of essential oils from flowers, leaves and aerial parts of Tunisian <i>Dittrichia Viscosa</i>','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1612789',24,'https://openalex.org/W2945248532','The objective of this work was to determine the chemical composition, the antioxidant and antibacterial activities of the essential oils (EOs) extracted by hydrodistillation from different organs of the D. viscosa: flowers, leaves and aerial parts. The main compounds identified by GC/MS are oxygenated sesquiterpenes. Among these compounds, (E)-nerolidol (40.7%) is the most abundant constituent of flowersâ essential oil while caryophyllene oxide (9.9%), isolongifolan-7-α-ol (10.3%) and α -eudesmol (9.1%) are the major constituents of the leavesâ essential oil. The presence of these compounds in the aerial partsâ essential oil is solely due to those of the flowers and leaves that constitute these aerial parts. The volatile extracts showed antioxidant effects with IC50 values ranging between 9.25 and 9.75 mg.mLâ1. On the other hand, EOs showed antibacterial effects on both Gram-positive and Gram-negative bacteria. The highest activity was obtained with flowersâ essential oil against Enterococcus faecalis and Escherichia coli.'),(1814,'10.1080/10412905.2019.1612790','Essential oils of <i>Cymbopogon schoenanthus</i> (L.) Spreng. from Algerian Sahara: chemical variability, antioxidant, antimicrobial and insecticidal properties','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1612790',24,'https://openalex.org/W2944669146','The essential oils (EOs) of Cymbopogon schoenanthus (L.) collected from six regions of the vast Algerian Sahara were analyzed for their chemical compositions by GC and GC-MS and tested for their antioxidant, antimicrobial and insecticidal activities. The EOs compounds-based cluster analysis permitted to distinguish three groups of similar chemical composition. Among the EOs, those of the group 3 were the most different, while those of group 1 and 2 were much more comparable. Overall, all the strains were sensitive to tested oils except E. coli which was generally the less sensitive bacteria. All the EOs showed weak antioxidant activity in the DPPH test while only those of the group 3 displayed low ferric reductive potential. Contrariwise, the piperitone-rich EOs (group 3) showed the highest effectiveness against the cowpea weevil (Callosobrochus maculatus) with the potent reduction of the femaleâs fecundity and the hatchability of laid eggs, especially EO from Tamanrasset province.'),(1815,'10.1080/10412905.2019.1622603','Chemical variability of <i>Hertia cheirifolia</i> (L.) Kuntze essential oils and incidence on antioxidant and anticholinesterase activities','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1622603',4,'https://openalex.org/W2969837521','The essential oils of Hertia cheirifolia, collected from different bioclimatic zones of Tunisia, were analyzed by GC-MS and GC-FID. The major compounds were α-pinene (17.51â60.31%), germacrene D (6.14â19.18%), unknown drimenin isomer (9.39â32.39%) and drimenin (0.46â33.61%). The essential oil composition varied significantly between populations. The chemical differentiation among populations occurs regardless their eco-geographic appurtenances. The species essential oils exhibited antioxidant and antiacetylcholinesterase activities. However, the level of activity varied between populations. The highest scavenging activity characterized the essential oils of the species collected from Sousse and Zaghouan (22.26 and 21.35 mg TE/gEO). Essential oils from Sousse possessed the uppermost inhibition of β-carotene bleaching (37.82 mg BHT equivalent/gEO). Essential oils from Sousse and Makthar exhibited the highest reducing capacity (162.05 and 171.80 µmol Fe2+/gEO). Essential oils from Siliana possessed the highest chelating ability (17.55 mg EDTA equivalent/gEO). Those from Siliana and Sousse exhibited the highest antiacetylcholinesterase activity (3.03 and 2.91 mg donepezil/gEO).'),(1816,'10.1080/10412905.2019.1631894','Green insecticide against Chagas disease: effects of essential oil from<i>Myrciaria floribunda</i>(Myrtaceae) on the development of<i>Rhodnius prolixus</i>nymphs','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1631894',23,'https://openalex.org/W2953705428','The main strategy of interrupting Trypanossoma cruzi transmission is to control the vector populations. Studies of new agents with activity against these vectors have a priority interest. This study evaluated the insecticidal activity of the essential oil of Myrciaria floribunda against nymphs of R. prolixus. M. floribunda was collected in Jurubatiba Sandbank (southeastern Brazil). Leaves were extracted by hydrodistillation and the essential oil analyzed by mass spectrometry and flame ionization gas chromatography. The pure essential oil at various dilutions or purified 1,8-cineole was topically applied to R. prolixus. Sesquiterpenes were the main group detected followed by monoterpenes. M. floribunda essential oil, but not 1,8-cineole, significantly increased mortality and disrupted metamorphosis. Overaged nymphs and juvenoid-like insects were also observed. Our data indicate the special metabolites in the essential oil of M. floribunda as promising candidates for studying insecticidal activity and for use as environmentally friendly control compounds to Chagas disease vectors.'),(1817,'10.1080/10412905.2019.1655491','Neuropharmacological profile of <i>Hypericum scabrum</i> L. essential oil in rats','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1655491',9,'https://openalex.org/W2969796892','Members of the genus Hypericum L. are traditionally used for various illnesses including depression. In this study, the effects of essential oil obtained from Hypericum scabrum L. on anxiety and depressive-like behavior were evaluated in dementia animal model. H. scabrum essential oil (1% and 3%) was applied to rats for 21 days by inhalation. Then, the rats were treated with scopolamine prior to behavioral tests: elevated plus maze and forced swimming test. H. scabrum essential oil increased the number of open arm entries and number of crossings within elevated plus maze as compared to scopolamine-alone treated group, demonstrating anxiolytic effect. Furthermore, depressive-like symptoms induced by scopolamine were reduced by H. scabrum essential oil inhalation as evidenced by increases in the swimming time and decreases in the immobility time within forced swimming test. These results show anxiolytic and antidepressant-like activities of H. scabrum essential oil in dementia rat model.'),(1818,'10.1080/10412905.2019.1656677','Effect of salinity on the antiparasitic activity of hyssop essential oil','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1656677',11,'https://openalex.org/W2970717848','The present work reports the effect of salt treatment on Hyssopus officinalis growth, essential oil (EO) yield and composition and the antiparasitic effects of the oil against the plant (Phytomonas davidi and Meloidogyne javanica) and human (Trypanosoma cruzi) parasites. Our results showed that salinity decreased plant growth and EO yield of hydroponically cultivated plants of H. officinalis with increasing NaCl levels. Salinity also induced changes in the chemical composition of treated hyssop EOs, decreasing the monoterpene and increasing the sesquiterpene groups. The oxygenated monoterpenes, represented primarily by isopinocamphone and pinocarvone, were the major chemical class. The EOs from treated H. officinalis showed moderate antiparasitic effects against T. cruzi, independent of the salt treatment, stronger salt-dependent effects on P. davidi and also a high salt-dependent nematicidal activity against M. javanica. Therefore, a moderate salt treatment reduced plant growth and EO yield but increased its biocidal effects on plant parasites (P. davidi and M. javanica).'),(1819,'10.1080/10412905.2019.1658649','Fractionation of four Colombian essential oils by countercurrent chromatography and evaluation of their antioxidant activity','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1658649',4,'https://openalex.org/W2971822675','High-speed countercurrent chromatography (HSCCC) is widely used for isolation of biologically active compounds of plant extracts and essential oils (EOs) in preparative scale. The objective of this work was the prefractionation of EOs from Lippia alba, Aloysia citriodora, Lantana armata and Xylopia aromatica by HSCCC and the evaluation of the antioxidant activity in vitro of their EOs and fractions. The antioxidant capacity was determined by two different in vitro assays: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical and 2,2ʹ-Azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation. EOs and their fractions showed a low-moderate ability to trap the radical cation ABTS+ and DPPH radical.'),(1820,'10.1080/10412905.2019.1660238','Variability in essential oil composition, antioxidant and antimicrobial activities of <i>Ruta montana</i> L. collected from different geographical regions in Algeria','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1660238',37,'https://openalex.org/W2972465448','Essential oils of Algerian Ruta montana collected from seven different regions characterized by diverse climatic conditions were investigated for their chemical components, oil yield diversity, antioxidant and antibacterial activities. The lowest (0.38%) and the highest (1.45%) yields in essential oils were observed in samples from Tizi ouzou and Djelfa, respectively. GC-MS and 13C-NMR analyses allowed the identification of forty components representing 87.8â99.2% of the total oils. The main components were 2-undecanone (27.2â81.7%), 2-nonanone (1.9â39.5%) and 2-nonanyl acetate (tr â 24.8%). Based on cluster analysis, two groups were determined, including high 2-undecanone and high 2-undecanone/2-nonanone/2-nonanol acetate groups. Antioxidant activity was evaluated by DPPH and reducing power assays. Samples from Mâsila and Djelfa (semi-arid regions) presented the highest antioxidant activity (IC50 = 49.6 ± 2.7 and 50.2 ± 3.3 mg/L, respectively). Antimicrobial activity was tested against eight microbial strains using the agar disc diffusion method. Overall, moderate activity was observed (inhibition zones\' diameters â¤18 mm). This variation confirmed the impact of the climatic conditions on yield and chemical composition of essential oils as well as their biological activities.'),(1821,'10.1080/10412905.2019.1662337','Chemical composition, antimicrobial activity, kinetics and mechanism of action of Himalayan-thyme (<i>Thymus linearis</i> Benth.)','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1662337',17,'https://openalex.org/W2972810332','In this study, antimicrobial activity of the essential oil (EO) and extracts of Himalayan-thyme (Thymus linearis Benth.) was evaluated against nine pathogenic microbial strains using disc diffusion and microdilution broth assays. The chemical composition of the EO was determined by gas chromatography-flame ionisation detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The molecular mechanism of action of the EO was investigated against three pathogenic bacteria (Staphylococcus aureus, Staphylococcus epidermidis and Enterococcus faecalis) and three fungal strains (Candida albicans, Candida glabrata, and Candida tropicalis) using the assays of protein leakage, and DNA and RNA leakage through the membrane. Major components of the EO were thymol (54.9%), γ-terpinene (16.6%) and p- cymene (5.2%). The EO showed broad-spectrum potent antibacterial and antifungal activity (MIC 240â990 µg/mL) against test strains. The EO damaged cell membranes and altered cell membrane permeability of test microorganisms. The EO showed a time- and dose-dependent bactericidal and fungicidal effect. It could act as a promising antimicrobial agent due to its short killing time.'),(1822,'10.1080/10412905.2019.1662338','Chemical composition and acaricidal activity of essential oils from two species of the genus <i>Bauhinia</i> that occur in the <i>Cerrado</i> biome in Brazil','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1662338',14,'https://openalex.org/W2976440336','Essential oils from the leaves of Bauhinia rufa and B. dumosa collected from the Cerrado biome in central Brazil were obtained by hydrodistillation and analyzed using GC and GC/MS. Both oils had a predominance of sesquiterpenes (B. rufa: 95.3 ± 0.5%; B. dumosa: 97.2 ± 1.1%). β-Caryophyllene (15.8 ± 0.5%), epi-α-cadinol (12.8 ± 0.4%), γ-muurolene (12.2 ± 0.4%) and α-cadinol (10.0 ± 0.5%) were identified as the major constituents of the B. rufa oil, whereas germacrene B (37.6 ± 1.2%) and (E)-nerolidol (29.1 ± 0.6%) were the major constituents of the B. dumosa oil. Both oils were toxic to Tetranychus urticae by fumigation (B. rufa: LC50 = 2.76 µL/L of air; B. dumosa: LC50 = 0.97 µL/L of air) and residual contact (B. rufa: LC50 = 30.46 µL/mL; B. dumosa: LC50 = 16.44 µL/mL). The results of the two-choice method revealed that the oils affect the behavior of the mite, interfering in its feeding and egg-laying preferences.'),(1823,'10.1080/10412905.2019.1677272','Characterisation of volatile and non-volatile compounds in pomelo by gas chromatography-olfactometry, gas chromatography and liquid chromatography-quadrupole time-of-flight mass spectrometry','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1677272',12,'https://openalex.org/W2981137557','Twenty-six key odourants were found in Hongxin and Shatian pomelo peel oils using aroma extraction dilution analysis (AEDA). trans-2-Dodecenal was identified to be the most potent key odourant, with a flavour dilution value of 100000 in Hongxin and 10000 in Shatian. Hongxin peel oil was found to be more floral while Shatian was green and peely. Gas chromatography coupled with quadrupole time-of-flight mass spectrometry (GC-QTOF/MS) revealed 22 volatiles that were undetected by the less sensitive GC-MS detector. Non-volatile compounds in the peel oils were identified and quantified using liquid chromatography (LC)-QTOF/MS. Besides organic acids, naringin and bergamottin were, concentration-wise, the dominant non-volatile compounds identified in the juices and peel oils, respectively. Pomelo juices had higher antioxidant capacities than their peel oils, and Shatian pomelos possessed higher antioxidant activities than Hongxin. The use of high-resolution detectors allowed for improved compound detection and identification in citrus, and may be applied to other complex natural products.'),(1824,'10.1080/10412905.2019.1684391','Productivity and essential oil composition of rosemary (<i>Rosmarinus officinalis</i> L.) harvested at different growth stages under the subtropical region of north India','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1684391',25,'https://openalex.org/W2993244809','Productivity and essential oil composition of rosemary (Rosmarinus officinalis L.) were evaluated under the subtropical region of north India. The crop was planted in mid-November and harvested at six different stages. The crop harvested at 225 days after transplanting yielded 88.03 L haâ1 essential oil which was at par with the yield obtained at 210 days (83.34 L haâ1). The essential oils extracted from whole aerial parts and leaves were analysed using gas chromatographyâflame ionization detector and gas chromatographyâmass spectrometry techniques. A total of 30 constituents, representing 96.2â98.2% of the total oil composition were identified. Major constituents of the oil were camphor (23.9â35.8%), 1,8-cineole (18.0â23.9%), α-pinene (4.5â14.4%), verbenone (6.5â12.4%), camphene (2.5â6.9%), limonene (2.1â2.8%), bornyl acetate (1.1â4.1%), α-terpineol (1.9â3.6%) and β-pinene (2.1â3.3%). In conclusion, cultivation of rosemary as a seasonal crop can produce good-quality essential oil in the subtropical region of north India.'),(1825,'10.1080/10412905.2019.1698468','Chemical composition and bioactivities of essential oils from <i>Pulicaria vulgaris</i> subsp. <i>dentata</i> (Sm.) Batt. growing in Tunisia','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1698468',19,'https://openalex.org/W2995592358','The essential oils of the aerial parts and roots (APEO and REO) of Pulicaria vulgaris subsp. dentata (Sm.) Batt. were analyzed by GC and GC-MS. Twenty-one compounds (97.2% of the total oil composition) were identified in the REO, with γ-irone (39.2%), 7-epi-silphiperfol-5-ene (19.3%), 2,5-dimethoxy-p-cymene (8.5%) and γ-himachalene (8.0%) as main constituents. The APEO was rich in cis-β-guaiene (59.7%), together with eighteen other compounds, accounting for 93.2% of the total oil composition. Antiradical and enzymatic antioxidant properties of the isolated oils were also evaluated. The REO exhibited the highest antioxidant activity using DPPH, ABTS, catalase and paraoxonase tests. Antimicrobial, cytotoxic and tyrosinase inhibiting properties of these essential oils have been also studied. APEO exhibited significant activity towards Pseudomonas syringae and Agrobacterium tumefaciens. The REO showed the most significant cytotoxic effect against HeLa cell line and the highest tyrosinase inhibition activity.'),(1826,'10.1080/10412905.2019.1700834','Physicochemical characterizations, antimicrobial activity and non-isothermal decomposition kinetics of <i>Cinnamomum cassia</i> essential oils','Journal of Essential Oil Research',2019,'https://doi.org/10.1080/10412905.2019.1700834',9,'https://openalex.org/W2995692185','The extraction of essential oils from Cinnamomum cassia bark and leaf was carried out by hydrodistillation (HD) and microwave-assisted hydrodistillation (MAHD). Chemical compositions of volatile compounds were determined by GC/MS, 1H-NMR and infrared spectroscopy analysis. The dominant constituents found in the essential oils were aromatic compounds (> 90%) including (E)-cinnamaldehyde (CAL) and (E)-cinnamyl acetate (CAC) as the major components. The thermogravimetry (TG) method was used to study thermal stability and volatilization of the oils at room temperature. The bark essential oils exhibited inhibitory effects against a bacterial strain, S. aureus and a yeast strain, S. cerevisiae at MIC value 200 µg/mL. The decomposition kinetic of the essential oils was studied via the isoconversional kinetic models using the TG data. Two the isoconversional models, FlynnâWallâOzawa (FWO) and KissingerâAkahiraâSunose (KAS) were used to determine activation energies (Ea) for decomposition of the essential oils.'),(1827,'10.1080/10412905.2019.1711212','<i>In vitro</i> scolicidal activity of <i>Thymus capitatus</i> Hoff. et Link. essential oil on <i>Echinococcus granulosus</i> protoscoleces','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2019.1711212',11,'https://openalex.org/W2998870750','Cystic echinococcosis remains a serious public health problem worldwide. Surgery is considered as the first option of treatment. Various investigations were carried out to find a convenient scolicidal agent for reducing the risk of post-surgical recurrence of the disease but most of them are associated with adverse side effects. The present study aimed to evaluate the in vitro scolicidal activity of Thymus capitatus Hoff. et Link. essential oil against Echinococcus granulosus protoscoleces. Three concentrations of essential oil (1, 2 and 3 mg/mL) were tested for 1 to 10 min on E. granulosus protosoleces and their viability was assessed by eosin staining test. The essential oil concentrated at 2 and 3 mg/mL killed 100% protoscoleces after 5 and 1 min, respectively. Furthermore, GC/MS and GC-FID analyzes indicated that carvacrol (82.4%) was the major component of the essential oil. The current investigation showed the potent scolicidal effect of T. capitatus essential oil in vitro.'),(1828,'10.1080/10412905.2020.1720834','Antioxidative potential and compositional variation among Origanum vulgare L. collected from different districts of Kumaun Himalayas, Uttarakhand','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1720834',6,'https://openalex.org/W3006489625','The present study investigated the compositional variation and antioxidant potential of Origanum vulgare L. (subsp. vulgare) collected from three districts of Uttarakhand, India. The essential oil composition was analyzed by GC and GC/MS, and the antioxidant potential was evaluated using 2,2ʹ-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ferric reducing antioxidant power (FRAP) activity and Fe2+-ferrozine test system for iron-chelating activity methods. The analysis allowed the identification of 22â36 compounds representing 87.84â92.95% of the total essential oil. Samples S1 and S2 contained a high amount of sesquiterpene hydrocarbons (26.37â47.25%), while sample S3 was rich in oxygenated monoterpenes (70.21%). The major component was (E)-caryophyllene in S1 and S2 samples (15.40â26.41%) and thymol (60.3%) in S3 sample. The S3 sample collected from the lowest altitude showed the highest oil yield and antioxidant activity.'),(1829,'10.1080/10412905.2020.1729880','Cytotoxic activity of <i>Ferula persica</i> gum essential oil on murine colon carcinoma (CT26) and Vero cell lines','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1729880',10,'https://openalex.org/W3007109159','In this study, murine colon carcinoma (CT26) as well as non-cancerous Vero cells were exposed to various concentrations of essential oil (EO) obtained from the gum of F. persica (0.125 Ã 10â9 to 20 µl/ml and 0.125 Ã 10â9 to 80 µl/ml, respectively) for 24 h. The cytotoxicity and apoptosis were determined using MTT assay and acridine orange/ethidium bromide (AO/EB) staining, respectively. Clonogenic assay was also performed. Among 28 compounds that were determined by GC/MS, the major constituent of the EO was α-pinene (27.1%). A dose-dependent cytotoxicity was observed on CT26 cells with IC50 value of 0.0010 µl/ml. The cytotoxicity on Vero cells was relatively low with IC50 value of 0.3247µl/ml. The EO induced apoptosis in both cells and colony formation was also inhibited. In conclusion, the EO obtained from the gum of F. persica has cytotoxic and apoptotic effects on CT26 cell line with lesser effects on Vero cells.'),(1830,'10.1080/10412905.2020.1733110','Chemometric analysis of geographic origins and compositions of <i>Citrus sinensis</i> (L.) Osbeck var âMaltaise demi sanguineâessential oil','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1733110',5,'https://openalex.org/W3009720048','The peelâs essential oil of the Tunisian Citrus sinensis (L.) Osbeck var âMaltaise demi sanguineâ cultivated in six regions and three bioclimatic stages was analyzed by gas chromatography. Essential oil yields were highly affected by the growing region and stage. The highest oil yield was observed at sub-humid stage: 1.41% in Oued-Mliz, 0.95% in Bizerte and 0.84% in Takelsa and the weakest yield percentage of 0.71% was found in Kairouan characterized by an arid superior stage. The main components limonene, linalool, α-terpineol, 4-Terpineol and β-myrcene showed signiï¬cant variations in dry region. Principal component analysis and hierarchical clustering of composition revealed high effect of the bioclimatic stage, the coastal location and the altitude. Besides this, the results of this investigation provided a preliminary evidence for specific markers to each region that could constitute a useful tool in the quality control and the determination of the botanical origin of the oils.'),(1831,'10.1080/10412905.2020.1737587','Phytochemical profiling, antioxidant and antimicrobial effectiveness of <i>Rosmarinus tournefortii</i> De Noe extracts issued from different regions of Algeria','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1737587',5,'https://openalex.org/W3015106419','Tidya Outaleba, Amine Yekkourbc, Mohamed Hazzita*, Abdelghani Zitounic & Nasseredine Sabaouca Département de Technologie Alimentaire, Ecole Nationale Supérieure d\'Agronomie, El-Harrach (ENSA), Alger, Algeriab Institut National de Recherche Agronomique d\'Algérie (INRAA), Station Mehdi Boualem-Baraki, Alger, Algeriac Laboratoire de Biologie des Systems Microbiens, Ecole Normale Supérieure de Kouba, El Bachir El Ibrahimi, Alger, Algeria'),(1832,'10.1080/10412905.2020.1740802','Antibacterial activity and synergism of the essential oil of <i>Nectandra megapotamica</i> (L.) flowers against OXA-23-producing <i>Acinetobacter baumannii</i>','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1740802',8,'https://openalex.org/W3014463977','Multidrug-resistant Acinetobacter baumannii has emerged as a problematic hospital-acquired pathogen. It is vital to search for new sources of antibiotics. Natural plant essential oils have several biological properties, including antimicrobial activity and may be valuable for new drug development. Chemical composition of the essential oil of Nectandra megapotamica flowers was assessed by Gas Chromatography/Flame Ionization Detector and Gas Chromatography/Mass Spectrometry analysis. Antibacterial activity against OXA-23-producing A. baumannii and synergism with antibiotics were performed by broth microdilution, time kill, and checkerboard methods. The essential oil of Nectandra megapotamica flowers showed a predominance of oxygenated sesquiterpenes and caryophyllene oxide was the main component. Survival curves showed a linear decrease in viable OXA-23-producing A. baumannii cell counts over time for the association between the essential oil of Nectandra megapotamica flowers and imipenem. Checkerboard assay with imipenem presented Fractional Inhibitory Concentration Index of 0.156, suggesting synergism. The synergistic effect of essential oil of Nectandra megapotamica flowers with imipenem could be a potential approach to combat multiresistant OXA-23-producing A. baumannii strains, and could be used as a drug delivery system, as an excipient for imipenem, reducing its dosage.'),(1833,'10.1080/10412905.2020.1741457','Composition of essential oils of<i>Mentha</i>species and their antimicrobial activity against<i>Aeromonas</i>spp.','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1741457',43,'https://openalex.org/W3013653473','The chemical composition of the essential oils of Mentha arvensis and Mentha piperita and their antimicrobial activity against twelve Aeromonas spp. isolates from tambaquis (Colossoma macropomum), an important native farmed fish species in Brazil, were evaluated. The oils were characterized using gas chromatography and mass spectrometry (GC/MS) and their antimicrobial activity was evaluated through the microdilution method. The essential oils of these Mentha species mainly comprised oxygenated monoterpenes (97.1% for M. arvensis and 86.2% for M. piperita) and menthol was the major compound of these oils (86.1% for M. arvensis and 33.8% for M. piperita). It was confirmed that these oils had antimicrobial activity against 12 isolates of Aeromonas spp., with minimum inhibitory concentration (MIC) and minimum bacterial concentration (MBC) ranging from 1,250 to 16,666.7 μg mLâ1. Better antimicrobial activity was achieved by the M. arvensis essential oil.'),(1834,'10.1080/10412905.2020.1743786','Antimicrobial, anticholinesterase evaluation and chemical characterization of essential oil <i>Phlomis kurdica</i> Rech. fil. Growing in Turkey','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1743786',23,'https://openalex.org/W3011624341','The Phlomis kurdica Rech.fil. (Lamiaceae) essential oil was investigated for its chemical constituents and in vitro biological activities. Volatile components were characterized, antimicrobial and anticholinesterase activities were performed. The oil was analyzed both by gas chromatography-mass spectrometry and gas chromatography-flame ionization detector, simultaneously. The in vitro antimicrobial microdilution method was used against Bacillus cereus ATCC 14579, Pseudomonas aeruginosa ATCC 10145, Escherichia coli NRLL B-3008, Staphylococcus aureus ATCC 6538, Helicobacter pylori ATCC 43504, Staphylococcus epidermidis ATCC 14990, and Candida albicans ATCC 90028, respectively. Additionally, the cholinesterase enzyme inhibition activities were tested in vitro using the Ellman method. A total of forty-four different volatile constituents were identified, where the main components were characterized as germacrene D (55.4%), (Z)-β-farnesene (11.2%), and hexadecanoic acid (8.4%), respectively. The P. kurdica oil showed moderate inhibition of cholinesterases, where inhibitory antimicrobial activity was against B. cereus among the tested microorganisms.'),(1835,'10.1080/10412905.2020.1746415','Screening of non-alkaloid acetylcholinesterase and carbonic anhydrase isoenzymes inhibitors of <i>Leiotulus dasyanthus</i> (K. Koch) Pimenov &amp; Ostr. (Apiaceae)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1746415',12,'https://openalex.org/W3015987396','The oxidant, cholinesterase, and carbonic anhydrase inhibitions of essential oils and their major compounds of Leiotulus dasyanthus and molecular docking studies of α-pinene and δ-3-carene were evaluated in this study. Phenolic constituents and antioxidant activity of samples were determined by Folin-Ciocalteuâs, DPPH, and TBA processes. Cholinesterase inhibition effect was evaluated through Ellmanâs method. GC-FID and GC/MS were used for analysing of essential oils. The root oil got the highest total phenolic content (898.87 mg/g). The utmost activity was shown flower oil (29.31 μg/mL) in the DPPH test. The root oil indicated considerable inhibition towards acetylcholinesterase (21.92%) and butyrylcholinesterase (91.33%) enzymes, respectively. α-pinene and δ-3-carene indicated high acetylcholinesterase inhibitory activity (66.44 and 48.71%, respectively). Cytosolic hCA I and II isoenzymes were influentially inhibited by flower and aerial part oils with 1.694 and 1.677 µM IC50 values, respectively. 1-Dodecanol (7.8%); β-pinene (63.3%), α-pinene (20.5%); octyl acetate (14.7%); hexyl octanoate (55.1%) were characterized as principle compounds of aerial parts, roots, flowers, and fruits respectively.'),(1836,'10.1080/10412905.2020.1749946','Essential oils and lipids from the flowers of two varieties of <i>Ocimum basilicum</i> L. cultivated in Uzbekistan','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1749946',10,'https://openalex.org/W3016496488','In the current work the flowers of green and dark purple Ocimum basilicum L. varieties cultivated in Uzbekistan were comparatively studied in terms of chemical composition of the lipids, essential oils and fatty acids by using TLC, GC-FID and GC-MS techniques. The lipid composition of flowers both basil varieties comprised biologically active substances such as unsaturated fatty acids, phospholipids, phytosterols, carotenoid pigments and essential oils. The flower volatiles were obtained by hydrodistillation technique and subjected to GC analysis. Enantiomeric status of chiral volatile compounds was determined by analysis on chiral RTex cyclodextrin column. It is revealed that the flowers of green and dark purple basil produce essential oils with a high abundance of oxygenated monoterpenes with linalool (52.4% and 72.3%, respectively) as a major constituent. The flower volatiles from the green basil were distinct from that of dark purple variety, having strong sweet-spicy odor due to higher percentage of phenylpropanoid methyl chavicol (19.5%).'),(1837,'10.1080/10412905.2020.1749947','Effect of growing seasons on the leaf essential oil composition of <i>Citrus</i> species that are cultivated in Egypt','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1749947',29,'https://openalex.org/W3018304602','Essential oil (EO) of Citrus has some biological and pharmaceutical properties; thus, it can be used in food and drug industries. Changes in growing seasons play important roles in physiological processes of Citrus EO especially that extracted from young leaves. The aim of this study was to evaluate the EO extracted from young leaves of twelve Citrus species in different seasons (winter, spring, summer and autumn) under Egyptian conditions. The Citrus species in this investigation were Valencia Orange, Navel Orange, Sour Orange, Lemon, Volkamer Lemon, Lime, Persian Lime, Sweet Lime, Mediterranean Mandarin, Dancy Tangerine, Grapefruit and Shaddock. The EOs of young leaves were extracted by hydrodistillation method (HD), and then analyzed by GC and GC/MS. Data were statistically analyzed using ANOVA. Sabinene was identified as the major component in EO isolated from Valencia Orange, Navel Orange and Grapefruit while linalool was the main compound in EO of Sour Orange, Mediterranean Mandarin and Dancy Tangerine. The major constituent of EO produced from Lemon, Volkamer Lemon, Lime, Persian Lime and Sweet Lime was limonene, but it was E-phytol in Shaddock EO. The greatest contents (%) of EO isolated from young leaves and major constituents of all Citrus species were detected in the samples harvested during the spring season. The EO constitutes that detected in leaf EO were classified into five chemical groups âmonoterpene hydrocarbons (MH), oxygenated monoterpenes (OM), sesquiterpene hydrocarbons (SH), oxygenated sesquiterpenes (OS) and oxygenated diterpenes (OD)â. It was found that the detected compounds of EO extracted from various Citrus species belonged to MH, OM, SH and OS, except the compounds of Dancy Tangerine and Shaddock were belonged to MH, OM, SH, OS and OD. Different changes were observed in the minor components and various chemical groups in different growing seasons.'),(1838,'10.1080/10412905.2020.1750495','Chemical composition of the essential oils of Artemisia species from Iran: a comparative study using multivariate statistical analysis','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1750495',18,'https://openalex.org/W3018306323','Essential oils (EOs) of eight Artemisia specieswere analyzed by gas chromatography-mass spectrometry (GC/MS) and gas chromatography/ï¬ame ionization detector (GC-FID) at vegetative, budding and flowering stages. Regarding the cluster analysis and principal component analysis, group A of cluster analysis (A. campestris) was highly correlated with Methyleugenol and Acenaphthylene and group B of cluster analysis (A. spicigeria, A. sieberi, A. annua, A. vulgaris and A. diffusa(were highly correlated with 1,8-cineole and Camphor. Also group C of cluster analysis (A. absinthium and A. scoparia) were highly correlated with β-Pinene. Methanol crude extracts of leaves of Artemisia species were obtained at vegetative stage. Antioxidant activities by DPPH and Reducing Power (RP) methods, flavonoid and flavonol contents by aluminum chloride (AlCl3) and total phenols by Folin-ciocalteu assay were measured. The greatest amount of antioxidant activity, TP, TF and TFl were found in A. scoparia and the lowest in A. vulgaris.'),(1839,'10.1080/10412905.2020.1750497','Variation in essential oil composition in rhizomes of natural populations of <i>Hedychium spicatum</i> in different environmental condition and habitats','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1750497',19,'https://openalex.org/W3019191352','Hedychium spicatum Sm. is a perennial, rhizomatous, essential oil bearing, plant belongs to the family Zingiberaceae. In the present study, essential oil composition in rhizome part was analysed among 16 populations located in diverse habitat conditions in west Himalaya. A total of 39 compounds were identified accounting 89.59â98.51% of the volatile constituents. Among these, 1,8-cineole was recorded as a single major component (41.63%), followed by β-eudesmol (10.42%), α-elemol (8.08%), cadin-4-en-10-ol (7.90%), α-eudesmol (5.80%) and linalool (4.09%). Some essential oil components such as, 1,8-cineole, carissone, trans-pinocarveol, δ-terpineol, β-pinene, α-terpineol, terpinen-4-ol and α-thujene exhibited significant (p < 0.05) negative relationship with altitude. Different habitat conditions also largely influenced the oil composition and therefore can be promoted as specific compound rich essential oil. The result of this study can be utilised for selection of specific compound rich group for its use in flavour, fragrance, cosmetic or medicines.'),(1840,'10.1080/10412905.2020.1752320','Chemical composition and acaricidal activity of <i>Lantana camara</i> L. and <i>Lantana montevidensis</i> Briq. essential oils on the tick <i>Rhipicephalus microplus</i>','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1752320',17,'https://openalex.org/W3021606962','This study aimed to analyze the chemical composition and to evaluate the essential oil activity of Lantana camara and Lantana montevidensis against R. microplus larvae and engorged females. Analysis of essential oils by GC and GC/MS allowed the identification of 34 constituents. L. camara oil was mainly composed of Bicyclogermacrene, isocaryophyllene, valencene and germacrene-D. L. montevidensis oil was mainly composed of β-caryophyllene, germacrene-D and bicyclogermacrene. Acaricidal activity of the essential oils against R. microplus was evaluated by larval sensitivity and tests using engorged females. L. camara and L. montevidensis essential oils possessed high activity against engorged females with LC50 of 2.9 and 3.3 mg/mL, respectively. Acaricidal activity against R. microplus was moderate with LC50 of 8.8 and 9.2 mg/mL for the L. camara and L. montevidensis essential oils, respectively. LC50 values indicated greater oil activity against engorged females in relation to larvae, with a relevant acaricidal activity against R. microplus.'),(1841,'10.1080/10412905.2020.1754937','Biological, chemical, and aroma profiles of essential oil from waste celery seeds (<i>Apium graveolens</i>L.)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1754937',22,'https://openalex.org/W3018042930','The aim of this study was to determine the chemical profile of monoterpenes (including identification of stereoisomers) contained in celery seed essential oil derived from waste celery seeds (Apium graveolens L.), which did not meet commercial quality criteria as a sowing material, and to evaluate the biological activity and sensory profile of the oil. The main constituent of the oil was (R)-(+)-limonene (75.06%). The antimicrobial activity of the oil was assessed using the impedimetric method to find its minimum inhibitory concentration (MIC) against the bacteria (Bacillus subtilis (MIC 50 μL/mL), Staphylococcus aureus (MIC 2 μL/mL), Escherichia coli (MIC 20 μL/mL) and Pseudomonas aeruginosa (MIC 30 μL/mL)) as well as the fungi (Candida vini (MIC 50 μL/mL), Aspergillus niger (MIC 50 μL/mL), and Penicillium expansum (MIC 50 μL/mL)). The oil showed high radical scavenging activity for DPPH (IC50 = 89.11 g/l). Fragrance perception depended on the sex of the panellists.'),(1842,'10.1080/10412905.2020.1772134','Chemical variability of essential oils of three subspecies of <i>Thymus munbyanus</i> Boiss. &amp; Reut. from Western Algeria','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1772134',11,'https://openalex.org/W3036928606','Chemical composition of the essential oils of three subspecies of Algerian Thymus munbyanus Boiss. & Reut. (subsp. abylaeus, subsp. ciliatus and subsp. coloratus) aerial parts have been investigated. GC and GC/MS analysis allowed the identification of sixty-eight compounds accounting for 99.3%, 99.7% and 98.2% of collective essential oils of three subspecies. The main components of three collective essential oils were: α-terpinyl acetate (51.7%), α-terpineol (9.7%), borneol (6.8%) and bornyl acetate (5.2%) for subsp. abylaeus; carvacrol (65.7%), γ-terpinene (13.6%) and p-cymene (7.9%) for subsp. ciliatus and camphor (25.9%), myrcene (16.9%), 1,8-cineole (6.5%) and camphene (6.2%) for subsp. coloratus. Intra-species variations of chemical compositions of essential oil from thirty-five Algerian samples were also investigated using statistical analysis. Essential oils samples were discriminated in three main clusters confirming relation between the chemical compositions and taxonomical differentiation between the three subspecies. These results confirm chemotaxonomic differentiation of all subspecies of T. munbyanus.'),(1843,'10.1080/10412905.2020.1773328','Seasonal variations of essential oils from five accessions of <i>Mentha longifolia</i> (L.) L. with selected chemical profiles','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1773328',10,'https://openalex.org/W3046109185','ABSTRACT Essential oil (EO) yield and composition of five accessions of Mentha longifolia (L.) L. (leaves) were determined throughout their vegetative cycle by GC-MS and GC-FID analysis. These accessions were selected based on TLC profiles of dichloromethane extracts from wild individuals. The profile rich in α-terpinyl acetate and 8-acetoxy carvotanacetone has not been previously reported. The maximum value of EO yield was obtained in advanced flowering stage. The major composition changes were noted at the beginning of the vegetative cycle, whereas more stability was found during the flowering stage. Thus, significant changes in the major compounds were found in some accessions: piperitone and piperitenone oxides, α-terpineol acetate and 8-acetoxy carvotanacetone, which showed a considerable increase (6.0% to 20.1%) during the vegetative growth, the same way that pulegone and piperitenone oxide in other accessions. As biological activities depend on EO composition, the knowledge of its seasonal changes should be emphasized.'),(1844,'10.1080/10412905.2020.1779139','Radical scavenging activity of the essential oils from <i>Croton grewioides</i> Baill accessions and the major compounds eugenol, methyl eugenol and methyl chavicol','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1779139',28,'https://openalex.org/W3102494244','Due to the potential of phytochemicals as therapeutic agents, there is increased interest in plant compounds with this biological activity, such as the essential oils of medicinal and aromatic plants. This study assessed the antioxidant activity of essential oils from the species Croton grewioides and its major compounds (CGR106 and CGR126 â 29.51% and 42.68% of eugenol; CGR126 and CGR112 â 45.97% and 85.58% of methyl eugenol; CGR106 â 59.85% of methyl chavicol). Antioxidant activities were evaluated by the systems 2,2-diphenyl-1-picryl-hydrazyl (DPPH), 2,2ʹ-azinobis (3-ethylbenzoathazoline-6-sulfonic acid) (ABTS), Ferric Reducing Ability (FRAP) and co-oxidation of β-carotene/linoleic acid. The best results were found in the essential oils CGR106 and CGR126, from C. grewioides. Samples with eugenol in their composition showed greater free-radical stabilization capacity. Essential oils of both accessions presented antioxidant capacity in the methods tested.'),(1845,'10.1080/10412905.2020.1787883','Antibacterial and antioxidant activity of wild-growing <i>Angelica</i> species (Apiaceae) from Balkan Peninsula against human pathogenic bacteria','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1787883',9,'https://openalex.org/W3039558481','This is the first study on antioxidant and antibacterial activity of essential oils of A. sylvestris and A. pancicii against the human pathogens. In the oil of A. sylvestris, the main compounds were limonene (75.3%) and α-pinene (9.6%), while in the oil of A. pancicii the main compounds were β-phellandrene (54.9%), α-pinene (14.5%) and α-phellandrene (4.05%). The results of ABTS have shown that antioxidant activity ranged between 1.48 and 2.07 mg VitC/g for 30 μL/mL of tested concentration. IC50 values in DPPH assay ranged between 59.895 and 149.498 mg/mL of tested concentrations. Antibacterial activity of the essential oils and antibiotics against pathogenic bacterial strains was investigated using microwell dilution method. The minimum inhibitory concentrations (MIC) and minimum bactericidal concentrations (MBC) were in the ranges of MIC/MBC = 0.11/54.40 mg/mL and 0.10/48.20 mg/mL (respectively). When combined with antibiotics, the oils have exhibited synergism and may reduce the minimum effective dose of antibiotics required and minimize its side effects.'),(1846,'10.1080/10412905.2020.1787884','Cytotoxic effect and molecular docking studies of essential oils of <i>Cymbocarpum erythraeum</i> (DC.) Boiss. (Apiaceae) as potential inhibitors of cholinesterase','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1787884',7,'https://openalex.org/W3041110381','This investigation displays antioxidant potential of Cymbocarpum erythraeum essential oils and their biological effects like cytotoxic and anticholinesterase. The antioxidant capacities of the essential oils were estimated by DPPH, TBA, TOS assays. The anticholinesterase activity of essential oils was estimated utilizing Ellman method. The human U-87MG and PC-3 were handled and measurements were estimated by MTT test. The root essential oil showed high cytotoxic activity on PC-3 cells with 48.33% whereas aerial part essential oils indicated high cytotoxic activity on U-87MG cells with 34.62% at 0.03 mg/L. Root oil presented the highest acetylcholinesterase and butyrylcholinesterase inhibition (IC50: 113, 197 µM, respectively). The GC-FID and GC-MS assays showed that major components of aerial part with flowers and root oils were (E)-2-decenal (52.1%); (E)-2-dodecenal (36.1%), and (E)-2-tetradecenal (22.3%), respectively. (E)-2-dodecenal was a major compound of root il and exhibited AChE and BuChE inhibitory (IC50: 100, 136 µM, respectively) and antioxidant effects.'),(1847,'10.1080/10412905.2020.1787885','Chemical composition and antimicrobial activity of Java citronella (<i>Cymbopogon winterianus</i> Jowitt ex Bor) essential oil extracted by different methods','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1787885',41,'https://openalex.org/W3040880408','ABSTRACT Citronella (Cymbopogon spp.) essential oil is an important component of various fragrances, cosmetics, and household products. In this study, comparative chemical composition and antimicrobial activity of Java citronella (Cymbopogon winterianus Jowitt ex Bor) essential oil, extracted by different methods, namely hydro-distillation and steam-distillation were determined by GC, GC-MS, and disc diffusion assay and microdilution broth assay. Major constituents of the essential oil were citronellal (2.2â55.4%), geraniol (14.2â53.0%), citronellol (8.2â16.4%), isopulegol (0.3â12.6%), elemol (0.8â8.2%), and limonene (0.2â5.0%). The essential oils showed inhibition of test bacteria with minimum inhibition concentration (MIC) in the range of 250â1000 µg/mL and showed anticandidal activity with MIC in the range of 125â500 µg/mL. In general, the oils were moderately active against Gram-positive and Gram-negative bacterial strains and also showed good activity against Candidal strains. The essential oils extracted from the herbage by different techniques exhibited variations in their yield, chemical composition, and antimicrobial activities.'),(1848,'10.1080/10412905.2020.1787886','Chemical composition of petitgrain (leaf) essential oil of different <i>Citrus</i> rootstocks and scion cultivars','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1787886',8,'https://openalex.org/W3039746662','Petitgrain essential oil of nine rootstocks and eight Citrus scion plants were analyzed by GC/MS and GC-FID. For the rootstocks, linalool and caryophyllene oxide were the most recurrent chemotypes. Hydrocarbon terpenes was the main chemical class; some oils presented oxygenated monoterpenes as the main class. The âBitterâ orange petitgrain oil presented high amounts of esters, the âTaquariâ trifoliate oil has not presented hydrocarbon terpenes, and the âSwingleâ citrumelo oil only presented oxygenated compounds. Scion cultivar analysis showed petitgrain oils with sabinene, geranial, limonene and methyl-N-methyl anthranilate chemotypes. Most of the oils were composed mainly by hydrocarbon monoterpenes, with lesser content of terpene alcohols. Two scion cultivars presented the methyl-N-methyl anthranilate chemotype and smaller contents of hydrocarbon monoterpenes; the other was mainly composed by oxygenated monoterpenes. The oil composition of some of these rootstocks and scion varieties may be a potential feedstock for use in chemical, pharmaceuticals, fragrances and cosmetic industries.'),(1849,'10.1080/10412905.2020.1789001','Chemical analyses of the essential oils from <i>Varronia curassavica</i> accessions in two seasons','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1789001',10,'https://openalex.org/W3043149441','This work aimed to analyze the chemical composition of the essential oils of Varronia curassavica accessions that were collected during the rainy (July 2015) and dry (January 2016) seasons. The essential oils were extracted by hydrodistillation and analyzed by GC/MS/FID. Fifty compounds were detected in the essential oils. The cluster analysis formed seven chemical clusters in the two harvest seasons. Only the accessions VCUR-302 and VCUR-502 presented major alterations in the chemical composition of their essential oil. These two accessions migrated from cluster 5 in the rainy season to cluster 6 in the dry season. Accession VCUR-105 had higher essential oil content in the rainy season (3.20%). Meanwhile, in the dry season, the accessions VCUR-003 (2.78%) and VCUR-101 (2.73%) were also productive, as well as VCUR-105 (2.84%). The bioactive compounds α-humulene and (E)-caryophyllene were detected in all of the accessions of their essential oils in both seasons.'),(1850,'10.1080/10412905.2020.1794988','Productivity, essential oil variability and antioxidant activity of <i>Ferula assa-foetida</i> L. oleo-gum-resin during the plant exploitation period','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1794988',10,'https://openalex.org/W3045386603','In the present study, productivity, essential oil variability and antioxidant activity of Ferula assa-foetida oleo-gum-resin (OGR) collected at different collection times (July, August, September, and October) were studied by using GC-FID-MS and DPPH assay. The amount of OGR (g/plant) and its oil content significantly affected by the collection time. The highest and the lowest amount of OGR was obtained in September (13.2 g) and July (6.3 g), respectively. The essential oil content (w/w %) was in the order of: July (9.1%)> August (8.2%)> September (7.8%)> October (7.4%). The total number of constituents was 47 in July, 47 in August, 43 in September and 44 in October, representing 97.7%, 98.6%, 96.8%, and 96.8% of the total oil, respectively. α-Pinene (18.2â48.6%), (Z)-propenyl sec-butyl disulfide (9.4â28.8%), β-pinene (6.2â11.5%), bicyclogermacrene (3.3â6.4%), (E)-propenyl sec-butyl disulfide (1.3â5.8%), germacrene D (2.0â3.9%) and (Z)-β-ocimene (1.1â3.6%) were the main components of the OGR oils. The highest radical scavenging (IC50 87.3 ± 5.1 μg/ml) of the collected OGRs was obtained in August.'),(1851,'10.1080/10412905.2020.1796832','Composition of the essential oils of five subspecies of <i>Scutellaria orientalis</i> from Turkey','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1796832',4,'https://openalex.org/W3047579391','ABSTRACT The chemical compositions of the essential oils obtained by hydrodistillation from aerial parts of five subspecies of Scutellaria orientalis L. (subsp. carica, subsp. haussknechtii, subsp. macrostegia, subsp. orientalis and subsp. santolinoides) were analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS), simultaneously. According to essential oil analysis in five subspecies of S. orientalis, germacrene D (57.2%), bicyclogermacrene (7.4%) and β-caryophyllene (5.2%) in subsp. carica; germacrene D (23.5%), β-caryophyllene (14.2%), bicyclogermacrene (9.0%) and caryophyllene oxide (8.1%) in subsp. haussknechtii; germacrene D (47.8%), β-caryophyllene (16.3%) and bicyclogermacrene (12.0%) in subsp. macrostegia; caryophyllene oxide (23.5%), germacrene D (20.1%) and β-caryophyllene (14.5%) in subsp. orientalis; germacrene D (42.1%), β-caryophyllene (13.7%) and bicyclogermacrene (11.3%) in subsp. santolinoides were determined as major components. To the best of our knowledge, this is the ï¬rst report on the chemical composition of the essential oil of four subspecies of S. orientalis.'),(1852,'10.1080/10412905.2020.1804001','Essential oils of <i>Marrubium</i> L. taxa from aegian province of Turkey','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1804001',5,'https://openalex.org/W3083452845','A comparative study on the essential oil (EO) compositions of seven Marrubium taxa from nine locations in Aegean province of Turkey was performed by this study. The essential oils analysed by gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS). The major compounds of all species were detected as sesquiterpenes; (Z)-β-farnesene, germacrene D, β-caryophyllene, caryophyllene oxide and bicyclogermacrene in variable rates for different taxa. Moreover, this is the first study on EO composition of endemic M. rotundifolium Boiss. and chemical variabilities of the EOs of other Marrubium taxa collected from Turkey.'),(1853,'10.1080/10412905.2020.1804002','Chemical composition and acaricidal activity of essential oils from fruits of <i>Illicium verum</i> and rhizomes of <i>Curcuma zedoaria</i> against <i>Dermacentor nitens</i> (Acari: Ixodidae)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1804002',12,'https://openalex.org/W3068762357','This study aimed to determine the chemical composition of essential oils (EOs) from fruits of Illicium verum and rhizomes of Curcuma zedoaria and evaluate the acaricidal activity against Dermacentor nitens, the tropical horse tick. The EOs were characterized by gas chromatography coupled with mass spectrometry analysis. Mostly, the chemical compounds found were (E)-anethole (88.32%) from I. verum, and 1,8-cineole (43.49%), curzerenone (13.40%) and camphor (12.29%) from C. zedoaria. The acaricidal activity was evaluated on D. nitens engorged females by Adult Immersion Test (AIT) using 40.0 mg mLâ1 of each essential oil. Illicium verum EOs showed a high acaricidal activity (89.6%) on the engorged females and also influenced on larvae hatching percent, while C. zedoaria presented low acaricidal activity (4.9%). The present data provide support for further investigation of I. verum EOs components as novel botanical acaricide to control D. nitens infestations.'),(1854,'10.1080/10412905.2020.1804469','Chemical composition and nematicidal activity of essential oils and their major compounds against <i>Meloidogyne graminicola</i> (Rice Root-Knot Nematode)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1804469',26,'https://openalex.org/W3049318227','Essential oils fromSyzygium aromaticum, Cymbopogon flexuosus and Cymbopogon martinii were isolated by hydrodistillation method and analysed by GC-FID and GC-MS. Eugenol (87.1%) and citral (69.4%), respectively were identified as major compounds in clove and lemongrass oils while geraniol (81.6%) and geranyl acetate (12.4%) in palmarosa oil. Essential oils were evaluated for nematicidal activity against J2s of Meloidogyne graminicola. Results showed the mortality of J2s in clove and lemongrass oils ranged from 70.00-92.50% to 77.50-97.50% and 63.75-92.50% to 72.5-97.50% and that of palmarosa oil showed 70.00-95.00% to 73.75-98.75% mortality at 31.12 to 500 ppm after 24 and 96 hours. Geraniol, citral (sum of neral and geranial) and eugenol were also evaluated for their nematicidal activity. Results showed that geraniol (75.00-95.00% to 78.75-98.75%) possessed highest mortality followed by citral (67.5-93.75% to 72.50-97.50%) and eugenol (66.25-93.75% to 73.75-98.75%) at 31.12 to 500 ppm. Efficacy of the oils and compounds were comparable with carbofuran at 62.5ppm (76.0-87.67%) and 31.25ppm (70.67-83.33%) after 24-96 hours. Results showed that palmarosa oil possessed highest mortality followed by lemongrass and clove oils due to the presence of their major compounds.'),(1855,'10.1080/10412905.2020.1805038','Differentiation of North-Western Balkan <i>Juniperus communis</i> L. (Cupressaceae) populations â ecological and chemophenetic implications','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1805038',9,'https://openalex.org/W3080928881','Juniperus communis or common juniper is the only conifer with pan-arctic distribution due to its polymorphic nature and high phenotypic plasticity. This taxon also produces large amounts of essential oil, which are stored in resin ducts in leaves (needles) and seed-cones. Leaf terpenoid composition of 97 individuals of common juniper from five populations in north-western Balkans was investigated. In total, 135 compounds were identified, representing on average 99.2% of the composition. Sabinene was the most abundant compound in most of the samples, followed by α-pinene and terpinen-4-ol. Two populations that were located deeper into the peninsula had a higher fraction of sesquiterpenes in comparison to the more coastal populations and one Julian Alps population. Multivariate statistical analyses also confirmed the separation of populations based on the essential oil composition. There was no correlation found between chemical composition and environmental factors. Chemophenetic implications are briefly discussed.'),(1856,'10.1080/10412905.2020.1808538','Hydrodistillation of <i>Trachelospermum jasminoides</i> Lindl. flowers. An analysis of essential oil, hydrolate and polyphenols content of the process wastes.','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1808538',8,'https://openalex.org/W3049507871','Trachelospermum jasminoides (Lindl.) is a woody evergreen plant of the Apocynaceae family mainly used as ornamental/hedge plant. Its stems and leaves are used in traditional Chinese medicine with the name of âLuoshitengâ. Although some studies have been devoted to the phytochemistry of luoshiteng, little is known about the chemical composition of its flowers. In this study, the volatile composition of the flowers of T. jasminoides has been studied. The Gas chromatographic â Mass spectrometry analysis (GC/FID-MS) of the essential oil and hydrolate allowed identifying 43 compounds with linalool as the main compound for both of them. Phytochemical investigation was completed by the High Performance Liquid Chromatography â Mass spectrometry (HPLC/DAD-ESI-MS) analysis of hydrodistillation wastes (liquid and solid) which revealed the presence of biologically active compounds such as chlorogenic acids and other polyphenols. This study contributes to the definition of the phytochemistry of T. jasminoides and provides the first data on the composition of the hydrodistillation wastes preparatory to their valorisation in the future.'),(1857,'10.1080/10412905.2020.1813212','A caryophyllene oxide and other potential anticholinesterase and anticancer agent in <i>Salvia verticillata</i> subsp. amasiaca (Freyn &amp; Bornm.) Bornm. (Lamiaceae)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1813212',66,'https://openalex.org/W3084147971','Songul Karakayaa, Serdar Volkan Yilmaza, Ãzlem Ãzdemirb, Mehmet Kocac, Nur Münevver Pınard, Betül Demircie , Kadir Yıldırıma, Oksana Sytarf*, Hasan Turkezb & K. Hüsnü Can Baserga Department of Pharmacognosy, Faculty of Pharmacy, Ataturk University, Erzurum, Turkeyb Department of Molecular Biology and Genetics, Faculty of Science, Erzurum Technical University, Erzurum, Turkeyc Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ataturk University, Erzurum, Turkeyd Department of Biology, Faculty of Science, Ankara University, Ankara, Turkeye Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkeyf Department of Plant Biology, Institute of Biology, Kiev National University of Taras Shevchenko, Kyiv, Ukraineg Department of Pharmacognosy, Faculty of Pharmacy, Near East University, Nicosia, Northern Cyprus'),(1858,'10.1080/10412905.2020.1829509','Evaluation of the effect of seasonal variation and organ selection on the chemical composition and antimicrobial activity of the essential oil of oriental-cedar (<i>Platyclaudus orientalis</i> (L.) Franco)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1829509',7,'https://openalex.org/W3095015233','The aim of this work was to analyze the composition of oriental cedar volatile oils (Platycladus orientalis (L.) Franco) obtained from leaves and cones, over one season cycle to study the effect of climate conditions on the chemical composition as well as antimicrobial activities of the collected oils. The oils yield varied according to the plant part as well as the season of collection. The major chemical components of the samples among the seasonal cycle were α-pinene, α-cedrol and 3-carene. Spring leaves and cones oils were the most active against E. coli, autumn leaves oils were the most active against S. aureus, while autumn cones and leaves oils were the most active against C. albicans. OPLS-DA indicated that p-cymen-7-ol and γ-muurolene were positively correlated to activity against S. aureus, β-funebrene and tricyclene were correlated to activity against E. coli while o-cymol and β-phellandrene were the positive contributors against C. albicans.'),(1859,'10.1080/10412905.2020.1829510','Oil-in-water emulsion formulation of cumin/carvi essential oils combination with enhanced antioxidant and antibacterial potentials','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1829510',26,'https://openalex.org/W3092438570','This study targets to explore the bioactivties of the essential oils (EOs) ofCuminum cyminum and Carum carvi alone and three combinations and the impact of the emulsification process on their bioactivities. The mixture of EOs exhibited high reducing power and antiradical activity as well as antibacterial activity. Combination at a ratio of 0.7: 0.3 (cumin-EO: carvi-EO) is effective, ameliorating the antioxidant (reducing power of EC50 value of 11 mg/ml and radical scavenging activity with IC50 value of 24 mg/ml) antibacterial power of the EOs (IZ of 42 and 47 mm against S. aureus and E. faecalis). The lowest droplet size and the highest stability of emulsion have an impact of 1.19 µm with enhanced antioxidant activity (reducing power of EC50 value of 12 mg/ml and radical scavenging activity with IC50 value of 22 mg/ml). This study demonstrated that the combination and emulsification have positive effect on the EOs activity.'),(1860,'10.1080/10412905.2020.1829722','Chemical composition of needle and twig essential oils from <i>Pinus krempfii</i> Lecomte, an endemic species to Vietnam','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1829722',3,'https://openalex.org/W3098293234','Pinus krempfii Lecomte is endemic to the central highlands of Vietnam. It is also known as Krempfâs pine or flat-needled pine. Two essential oil samples have been isolated from leaves and branches, respectively, and analyzed by a combination of chromatographic and spectroscopic techniques [GC(FID), GC-MS and 13C NMR]. The compositions of both oil samples were dominated by monoterpene hydrocarbons, α-pinene, limonene and myrcene. Sesquiterpene hydrocarbons were represented by (E)-β-caryophyllene and germacrene D. Camphorene (meta isomer) was identified at low content. The compositions of essential oil samples from P. krempfii have been compared with those of other essential oils from various species of Vietnamese pines.'),(1861,'10.1080/10412905.2020.1839583','Chemical profile and sensory evaluation of Bulgarian rose (<i>Rosa damascena</i> Mill.) aroma products, isolated by different techniques','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1839583',32,'https://openalex.org/W3111564256','Comprehensive chemical profiling of threeRosa damascena Mill. essential oil samples and two extracts (supercritical and subcritical) was performed by means of GC/MS/FID. As a result 85 compounds, representing 87.9-99.2% of the detected compounds, were identified by GC/MS and simultaneously quantified by GC-FID.The main aroma constituents in the essential oil sampleswere monoterpene alcohols citronellol (20.8-30.8%), geraniol (19.3-23.3%) and nerol (8.9-10.8%), followed by the stearopten fraction with nonadecane (12.0-17.5%), nonadecene (1.0-4.0%), heneicosane (4.0-5.8%) and heptadecane (1.8-2.5%) found in highest concentration. The chemical composition of the extracts was dominated by b-phenylethyl alcohol - 56.6% found in the subcritical sample and 46.7% in the supercritical one. Fatty acids esters, waxes and triterpenoids were found in the extracts as well. In addition, sensory evaluation of the rose aroma products was performed, demonstrating intense citrus, floral and balsamic notes for the essential oils and slight herbaceous and fruity notes for the extracts.'),(1862,'10.1080/10412905.2020.1839585','Chemical composition, antiradical, and enzyme inhibitory potential of essential oil obtained from aerial part of<i>Centaurea pterocaula</i>Trautv','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1839585',11,'https://openalex.org/W3097866452','The chemical composition, free radical scavenging, α-amylase inhibitory, and 5-lipoxygenase inhibitory activity of the essential oil obtained from the aerial parts of Centaurea pterocaula Trautv. were examined. Twenty-nine compounds corresponding to 93.2% of the oil were identified in the oil of C. pterocaula. Hexadecanoic acid (13.9%), caryophyllene oxide (11.5%), spathulenol (11.4%), (E)-β-damascenone (5.0%), hexahydrofarnesyl acetone (5.0%), and tetradecanoic acid (4.9%) were the main compounds of the oil. The oil exhibited good antiâinflammatory activity, inhibiting 5-lipoxygenase with an IC50 value of 86.22 µg/mL. The oil was found to be active against DPPH radical and α-amylase with IC50 values of 83.05 and 79.66 µg/mL respectively, while it showed moderate activity against ABTS radicals with IC50 value of 360.9 µg/mL. To the best of our knowledge, this is first report on the chemical composition of C. pterocaula essential oil from Turkey; as well as on the biological activity of its essential oil.'),(1863,'10.1080/10412905.2020.1839586','<i>Boswellia sacra</i>essential oil manages colon cancer stem cells proliferation and apoptosis: a new perspective for cure','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1839586',16,'https://openalex.org/W3106463861','Boswellia sacra Flueck essential oil is obtained from frankincense obtained from Boswellia sacra trees. The aim of this study was to investigate the in vitro anti-cancer activity of Boswellia sacra (BS) essential oil in CD133+ and CD133- Colo-320 cells. Essential oil was analyzed by GC-MS. CD133+ cells, cancer stem cells, were obtained from the Colo-320 by the MiniMACS system. Cytotoxicity were evaluated with MTT assay. Anti-cancer activity of BS essential oil was investigated by immunocytochemistry. 41 compounds were identified in the essential oil. 1:2 dilution BS essential oil was found to be active against all the cells for 24 h incubation. β-catenin immunoreactivity was significantly decreased in both BS essential oil-treated CD133+ and CD133- Colo-320 cells. Caspase-3 immunoreactivity significantly increased in BS essential oil-treated CD133- Colo-320 cells. We conclude that BS essential oil decreased β-catenin signaling molecules which play a crucial role in cancer cell proliferation. BS essential oil promoted apoptosis in CD133- Colo-320 cells.'),(1864,'10.1080/10412905.2020.1840450','<i>Hesperozygis ringens</i> (Benth.) Epling essential oil: antifungal activity and effect on ergosterol content of wood-decay fungi','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1840450',7,'https://openalex.org/W3117983945','This study aimed to evaluate the antifungal potential of the essential oil (EO) from Hesperozygis ringens leaves and its major compound pulegone against wood-decay fungi. In addition, their effect on mycelia ergosterol content was assayed. The EO was extracted by hydrodistillation and its chemical composition was analyzed by gas chromatography coupled to mass spectrometry and gas chromatography with flame ionization detector. Pulegone was isolated through column chromatography. The EO and pulegone were tested on white-rot fungi (Ganoderma applanatum and Trametes versicolor), and brown-rot fungi (Gloeophyllum trabeum and Lentinus lepideus) in five and three concentrations, respectively. Propiconazole was used as positive control. The EO inhibited T. versicolor growth while pulegone inhibited growth of both white-rot species. Pulegone presented lower half-maximal inhibitory concentration than the EO for white-rot fungi. Both EO and pulegone negatively affected white-rot fungi ergosterol contents. White-rot fungi, in general, were more susceptible to EO and pulegone.'),(1865,'10.1080/10412905.2020.1842260','Phytochemical composition, antioxidant and wound healing activities of<i>Teucrium polium</i>subsp.<i>capitatum</i>(L.) Briq. essential oil','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1842260',21,'https://openalex.org/W3108714442','Teucrium poliumis widely used in Algerian folk medicine as to treat wounds. The aim of this study was to evaluate the chemical composition, antioxidant and wound healing properties of Teucrium polium essential oil. The composition was obtained by a combination of GC-FID and GC-MS analyses. The antioxidant activity was evaluated by in vitro assays (total antioxidant capacity, DPPH and bleaching of β-carotene). The in vivo wound healing potential of an ointment containing 10% of T. polium essential oil was investigated. The main components were in this order: β-pinene, germacrene, α-pinene, myrcene, limonene, bicyclogermacrene, trans-β-guaiene, spathulenol and β-bourbonene. Teucrium polium essential oil displayed a moderate antioxidant activity. The in vivo experiments showed that 10% OEO accelerated the wound healing process in comparison with controls. This study provides a scientific rationale for the use of Teucrium polium essential oil in the treatments of wounds.'),(1866,'10.1080/10412905.2020.1848650','Volatile and non-volatile metabolite study of endemic ecuadorian specie <i>Piper lanceifolium</i> Kunth','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1848650',14,'https://openalex.org/W3108385937','Phytochemical study of P. lanceifoluim, used in the traditional medicine in the South of Ecuador, resulted in the isolation of one flavone called Sakuranetin (1), two benzoic derivative acid knows called: lanceaefolic acid methyl ester (2), and cyclolanceaefolic acid methyl ester (3). The structures of compounds were established by means of 1H- and 13C-NMR and MS data, and compared with literature data. The essential oils were obtained by hydrodistillation and then analysed by gas chromatography/flame ionization detector (GC/FID) and gas chromatography/mass spectrometry (GC/MS), a total of 35 constituents were identified, representing the 97.3% of the chemical composition. Safrole was the most abundant compound in the plant with 48.3%. Monoterpene hydrocarbons and oxygenated monoterpenes are the most important groups of compounds in the essential oil of P. lanceifolium, this oil exhibited a moderate antibacterial effect against Klebsiella pneumoniae (ATCC 9997).'),(1867,'10.1080/10412905.2020.1848652','Comparison of drying methods for the extraction of essential oil from dragonhead (<i>Dracocephalum moldavica</i> L., Lamiaceae)','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1848652',22,'https://openalex.org/W3109705831','In the present study, the effect of six different drying methods on the essential oil content and compositions of aerial parts of Iranian dragonhead was assessed. The highest and lowest essential oil contents (1.85 and 0.45%, respectively), were achieved in freeze-drying method and oven drying at 60°C, respectively. Essential oil analyses showed that the main constituents were geranyl acetate (56.5â33.2%), geranial (10.8â27.9%), neral (7.3â20.3%), and geraniol (6.7â13.5%). The high- est percentages of geranyl acetate (56.5%) and geraniol (13.5%) were obtained with oven drying at 60°C. Cluster analysis of the essential oil constituents demonstrated three main groups based on drying methods. Freeze drying of aerial parts of dragonhead was the most suitable method allowing high-essential oil yields and short drying time. On the other hand, the highest level of marker compounds such as geranyl acetate and geraniol was obtained with oven drying at 60°C.'),(1868,'10.1080/10412905.2020.1848653','Antimicrobial activity of essential oils from <i>Lippia sidoides, Ocimum gratissimum</i> and <i>Zingiber officinale</i> against <i>Aeromonas</i> spp.','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1848653',27,'https://openalex.org/W3109840741','The aim of this study was to evaluate the antimicrobial activity of Lippia sidoides, Ocimum gratissimum and Zingiber officinaleâs essential oils against Aeromonas spp. isolates from Colossoma macropomum, and to determine their chemical composition. Essential oils were obtained through hydrodistillation and their chemical composition analyzed using gas chromatography coupled to mass spectrometry. The antimicrobial activity of the oils was evaluated by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The major compounds were thymol (76.6%), p-cymene (6.3%) and (E)- β-caryophyllene (5.0%) in L. sidoides; eugenol (43.3%), 1,8-cineole (28.2%) and β-selinene (5.5%) in O. gratissimum; and geranial (23.2%), neral (16.7%) and 1,8-cineole (15.8%) in Z. officinale. All the essential oils evaluated showed bactericidal action against isolates of Aeromonas spp., with MIC and MBC ranging from 625 to 5,000 μg mLâ1. We highlight the L. sidoides oil with the best antimicrobial activity (MIC and MBC ranging from 625 to 1,250 μg mLâ1).'),(1869,'10.1080/10412905.2020.1857853','Chemical constituents of the essential oil of endemic <i>Teucrium luteum</i> subsp. <i>flavovirens</i> (batt.) Greuter &amp; burdet collected from two localities in Morocco','Journal of Essential Oil Research',2020,'https://doi.org/10.1080/10412905.2020.1857853',5,'https://openalex.org/W3111401202','The chemical composition of the essential oils was obtained by hydrodistillation from the aerial parts of Teucrium luteum subsp. flavovirens collected from two different localities from south-east of Morocco and were analyzed by gas chromatography (GC-FID) and gas chromatographyâmass spectroscopy (GC-MS). The essential oils yields were 0.9% and 0.94% (v/w) for sample A and sample B, respectively. Sixty-three and fifty-five compounds were identified in the oil samples which constituted 89.9% and 93.0% of the total oils, respectively. The major constituents in sample A were E-Nerolidol (31.0%), β-Pinene (6.9%), β-Elemol (5.0%) and α-Pinene (4.5%), while those of sample B were β-Elemol (16.4%), α-Pinene (12%), (E)-β-Caryophyllene (7%), α-Humulene (6.4%), β-Pinene (5.7%). To the best of our knowledge, this is the first report on the chemical composition of the essential oil of T. luteum subsp. flavovirens from the South eastern Morocco.'),(1870,'10.1080/10412905.2020.1871085','Chemical compositions and biological activity of essential oils from four populations of <i>Satureja macrantha</i> C.A.Mey','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2020.1871085',13,'https://openalex.org/W3122560886','Satureja macrantha C.A.Mey. is a medicinal plant which produces essential oils with antibacterial and antifungal activity. This study was carried out to determine the chemical composition of essential oils obtained from four Satureja macrantha populations growing in Iran, and to evaluate their antioxidant and antibacterial activities. The essential oils were obtained by hydrodistillation and analyzed by GC-FID and GC/MS. The main identified constituents were p-cymene, γ-terpinene, thymol and carvacrol. Although the population from Khodafarin was rich in thymol (36.5%), the population from Arasbaran showed a high content of p-cymene (34.7%). In comparison, the populations from Marand and Kaleybar possessed high quantities of carvacrol (42.4% and 48.6%, respectively). The radical scavenging activity against the DPPH radical was noteworthy with IC50 values in the range of 5.6â62.9 µg/mL. The essential oils displayed minimum inhibitory and minimum bactericidal concentrations in the range of 4.6â37.5 µg/mL.'),(1871,'10.1080/10412905.2021.1873867','The influence of natural deep eutectic solvent glyceline on the yield, chemical composition and antioxidative activity of essential oil from rosemary (<i>Rosmarinus officinalis</i> L.) leaves','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1873867',24,'https://openalex.org/W3127703639','Essential oil from rosemary (Rosmarinus officinalis L.) leaves was isolated by conventional hydrodistillation using hydromodulus of 1/15 m/v and by distillation after the plant material pretreatment with 10% v/v aqueous solution of natural deep eutectic solvent glyceline. Qualitative and quantitative composition of the oil was determined by GC/MS and GC/FID analyses, while its antioxidant activity was investigated by DPPH assay. The yield of the essential oil was higher after the pretreatment of the leaves. The distillation method affected the quantitative composition of essential oil, but not its qualitative composition. The essential oil from the pretreated leaves had a higher content of camphor, verbenone and borneol (33.3%, 12.2% and 8.3%, respectively) and better antioxidant activity than the oil obtained by classical hydrodistillation. The advantage of the pretreatment method is the effective improvement of the extraction efficiency of rosemary essential oil from rosemary leaves.'),(1872,'10.1080/10412905.2021.1885510','Variation in essential oil composition, anatomical, and antioxidant characteristics of <i>Achillea filipendulina</i> Lam. as affected by different phenological stages','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1885510',20,'https://openalex.org/W3131352112','Achillea filipendulina is a ornamental plant with various biological and pharmaceutical properties. Essential oil (EO) yield and composition, polyphenolic content, antioxidant activity and anatomical traits were assessed during four developmental phases viz. five leaves appearance, sprouting, 50% and 100% flowering. The yield of EOs ranged from 0.22% to 0.78% at five leaves appearance stage and 100% ï¬owering stage, respectively. Samples collected at 100% flowering possessed the highest monoterpenes and the lowest sesquiterpenes derivatives compounds. 2,7-dimethyl-4(E),6-octadiene-2-ol was the most prominent component. The highest EO antioxidant activity was also observed at full-flowering stage. Also, 50% flowering stage contained the highest antioxidant capacity in comparison to the other phases. Finally, 50% flowering phase can be suggested as the optimal harvesting time for gaining high antioxidant capacity of phenolic extracts, while 100% flowering stage was more suitable in respect to favorite EO components and their antioxidant activity in this species.'),(1873,'10.1080/10412905.2021.1886186','Chemical characterization, antimicrobial and antioxidant evaluation of <i>Cymbopogon jwarancusa</i> (Jones) Schult. essential oil','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1886186',4,'https://openalex.org/W3132530381','The present study describes the results of phytochemical, antimicrobial and antioxidant study on the essential oil of Cymbopogon jwarancusa from India. The major constituents identified were cis-p-menth-2-en-1-ol (25.3â31.8%), trans-p-menth-2-en-1-ol (14.0â16.6%), δ-2-carene (11.8â15.8%), cis-p-menth-1-en-3-ol (10.5â14.2%) and trans-p-menth-1-en-3-ol (8.0â9.2%). Significant quantitative variations in composition were noticed during annual growth in different harvesting seasons. The essential oil exhibited significant antibacterial activity against Mycobacterium smegmatis, methicillin resistant Staphylococcus aureus, Staphylococcus epidermis and Streptococcus mutans. However, in the antifungal assay, Candida kefyr, Candida albicans, Candida tropicalis and Candida krusei were found to be more susceptible to essential oil of C. jwarancusa. The essential oil exhibited dose dependent antioxidant activity in DPPH and nitric oxide scavenging assay.'),(1874,'10.1080/10412905.2021.1895336','Comparative study of <i>Elyonurus muticus</i> and <i>Cymbopogon</i> essential oils: potential as food preservative and surface coating of strawberries','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1895336',14,'https://openalex.org/W3139214672','Carlos Eduardo Bortolan Toazza, Caroline Marques*, Wanderlei do Amaral & Maria Lucia MassonDepartment of Chemical Engineering, Graduate Program in Food Engineering, Federal University of Paraná, Curitiba, Brazil'),(1875,'10.1080/10412905.2021.1899993','Essential oil of Myrciaria tenella (DC.) O. Berg: effects of distillation time on its chemical composition and evaluation of its anti-inflammatory and antinociceptive effects','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1899993',6,'https://openalex.org/W3148244225','The objective of the present study was to characterize the essential oil of Myrciaria tenella (MTEO) leaves, to determine the effects of distillation time (1 to 5 h), and to evaluate its action on acute pain and inflammation both in vivo and in vitro. MTEO was obtained by hydrodistillation for 4 h and 36 compounds were detected, mainly consisting of hydrocarbon terpenes such as β-pinene (21.46%), α-pinene (19.43%), E-caryophyllene (10.89%) and aromadendrene (9.17%). A high yield of α-pinene/β-pinene-rich MTEO was obtained after only 2 h of extraction. For in vivo biological assays, MTEO was administered to male Swiss mice, showing an action against hypernociception (acetic acid-induced abdominal writhing, formalin and Von Frey models) and inhibiting carrageenan-induced paw edema. Production of IL-6, TNF-α, IL-1β, PGE2 was reduced and production of IL-10 was increased, with no change in motor performance. MTEO also reduced cell production of NO and cytokines, in addition to inhibiting COX activity.'),(1876,'10.1080/10412905.2021.1917460','Chemical composition, safety and efficacy of<i>Pistacia vera</i>L. oleoresin essential oils in experimental wounds','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1917460',7,'https://openalex.org/W3158546751','The aims of the study were to evaluate the wound-healing properties in an in-vivo model of the essential oils from Algerian and Italian Pistacia vera L. oleoresins. The essential oils (EOs) were obtained by hydrodistillation of oleoresins from the trunk of plants. They were analyzed by GC-FID and GC-MS, α-pinene was the main constituent of both EOs. The wound-healing potential of P. vera EOs was investigated using an excision wound model in rabbits. The EOs were mixed with petroleum jelly to obtain a topical ointment with a final concentration of 5%. The percentage of the evolution of wound contraction was calculated and histological sections of tissues were examined. Both preparations possess wound-healing activities comparable to that of the reference drug Cicatryl-Bio. Some EOs exhibit a wound-healing potential suggesting that they could find a place in modern therapy.'),(1877,'10.1080/10412905.2021.1918276','Essential oil composition of <i>Cladanthus eriolepis</i> (Coss. ex Maire) Oberpr. &amp; Vogt, an endemic species to Morocco','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1918276',5,'https://openalex.org/W3158169897','Cladanthus eriolepis (C. eriolepis) (Coss. ex Maire) Oberpr. & Vog. is endemic to High Atlas (Dades Gorge and Todgha Gorge), the Anti Atlas and Saharan Morocco. It is known under the vernacular names âAlougjim, gtaa-eddib, laatetechaâ and âLamghizalâ. Two essential oil samples have been isolated from aerial parts and analyzed by combination of chromatographic and spectroscopic techniques [gas chromatography (GC) in combination with retention indices (RI), gas chromatography-mass spectrometry (GC/MS) and 13C-NMR spectroscopy]. The compositions of both oil samples were dominated by hemiterpene esters such as isobutyl isobutyrate (21.2% and 20.8% respectively) and isobutyl angelate (22.0% and 22.4% respectively). Other esters present at appreciable contents were 2-methylallyl isobutyrate (5.3% and 5.5%), 2-methylbutyl isobutyrate (5.7% and 5.8%), 2-methylallyl angelate (4.6% and 4.9%) and 2-methylbutyl angelate (7.7% and 7.2%) beside α-pinene (9.5% and 5.8%) and β-bisabolene (2.8% and 4.0%). The compositions of the investigated oil samples from C. eriolepis differed substantially with literature data and with those of other Cladanthus species growing wild in Morocco.'),(1878,'10.1080/10412905.2021.1936666','Effect of distillation methods on the leaf essential oil of some <i>Citrus</i> cultivars','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1936666',14,'https://openalex.org/W3172702296','This study aimed to characterize the chemical composition of the leaf essential oil (EO) of mandarin and tangor trees obtained by steam distillation and hydrodistillation. Leaf samples were collected during the pruning period from seven citrus cultivars in a property located in Pareci Novo, Rio Grande do Sul state, South Brazil. The leaves underwent hydrodistillation and steam distillation, and the obtained EO was analyzed by GC-MS and GC-FID. In general, the Citrus deliciosa mandarins had higher EO yields than the âPonkanâ and tangors in both methods. The Citrus deliciosa mandarin trees presented higher amounts of methyl N-methyl anthranilate and γ-terpinene. In the EO of âPonkanâ, âURSBRS Hadaâ and âMurcottâ, there was a predominance of linalool and terpinen-4-ol. The extraction method influenced the contents of the compounds mainly, while the genetic factors determined the variations in the composition of the essential oil of citrus leaves.'),(1879,'10.1080/10412905.2021.1937353','Insecticidal activity of <i>Cinnamomum camphora</i> Ness and Eberm var. <i>linaloolifera</i> Fujita leaf essential oil and linalool against <i>Anticarsia gemmatalis</i>','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1937353',13,'https://openalex.org/W3167900023','This work aimed to evaluate the insecticidal activity of the leaf essential oil of C. camphora and its major compound, linalool, on A. gemmatalis by ingestion. The individuals were evaluated in 24, 48, 72, and 96 h of exposure to the following concentrations of essential oil and linalool: 0.1, 0.5, 1.0, 1.5, and 2.0% v/v. The biometric parameters of the surviving pupae were also evaluated. The results indicated that C. camphora leaf essential oil was effective in controlling A. gemmatalis, with 96% mortality after 24 h of exposure (2.0% v/v). Linalool was more effective, causing higher mortality percentages in the same exposure time. Higher exposure times increased the mortality percentages at smaller concentrations. There was no evidence of residual or lasting toxic effects of both the essential oil and linalool on the surviving pupae since the biometric parameters of the pupae have not differed from the negative controls.'),(1880,'10.1080/10412905.2021.1937354','Chemical composition and antioxidant activity of<i>Ambrosia arborescens</i>Miller leaf essential oil from Peruvian Andes','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2021.1937354',5,'https://openalex.org/W4293661137','The chemical composition and antioxidant activity of the essential oil from the leaves of Ambrosia arborescens Miller grown in the Peruvian Andes were studied. One hundred and thirteen compounds were identified, which represents 94.7% of the total composition of the essential oil. Sesquiterpene hydrocarbons and oxygenated monoterpenes were the most represented classes of volatiles with 43.8% and 22.4%, respectively. The main constituents of the essential oil were β-acoradiene (15.3%) and chrysanthenone (11.3%). Antioxidant activities were examined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), ferric reducing antioxidant power (FRAP) and determination of lipid peroxidation in brain rat homogenates (LPO) assays. The essential oil had a free radical scavenging effect, and it displayed ferric reducing capacity and antioxidant activity by inhibition of LPO.'),(1881,'10.1080/10412905.2021.1941338','Antioxidant, anthelmintic and antibacterial activities of red juniper (<i>Juniperus phoenicea</i> L.) essential oil','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1941338',13,'https://openalex.org/W3176132825','This study investigated the antioxidant, anthelmintic and antibacterial activities of essential oil obtained from red juniper (Juniperus phoenicea) leaves. Red juniper essential oil yield was 0.80%. The GC-MS analysis of this essential oil showed that α -pinene (74.14%) was the predominant component. The anthelmintic activity assay of red juniper essential oil was performed on Haemonchus contortus using egg hatch assay (EHA) and adult wormâs motility assay (AWMA). In the AWMA, essential oil induced inhibition of 76.18% at 1 mg/mL. The antibacterial activity of red juniper essential oil was effective against six human pathogenic bacteria including Listeria monocytogenes, Staphylococcus aureus, Bacillus cereus, Salmonella enteritidis, Salmonella typhimurium and Escherichia coli). These results suggested that red juniper essential oil could also be employed for developing new anthelmintic, antimicrobial and antioxidant agents.'),(1882,'10.1080/10412905.2021.1943551','Scents from the Brazilian Atlantic Forest Biome: chemical composition of essential oils from the leaves and flowers of seven species of <i>Ipomoea</i> (Convolvulaceae)','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1943551',3,'https://openalex.org/W3177860023','Ipomoea alba, I. indica, I. amnicola, I. tiliacea, I. carnea, I. pes-caprae and I. batatas occur in fragments of the Atlantic Forest in the state of Pernambuco, Brazil. Essential oils from the leaves and flowers of these plants were analyzed using GC/FID and GC/MS. Ninety-one compounds were identified, accounting for more than 95% of the oils analyzed. Differences in the chemical profile were found among the Ipomoea oils. Greater chemical diversity was found in the leaf oils. β-Caryophyllene (leaves: 7.0 ± 0.6 to 42.1 ± 1.6%; flowers: 6.4 ± 0.8 to 36.5 ± 1.3%) was identified in abundance in all oils. cis-Cadina-1(6),4-diene was another sesquiterpene found in high percentages in the oils (11.8 ± 0.9 to 44.2 ± 1.7%), but was absent from the I. alba oils, in which the major constituent was germacrene D (leaves: 27.8 ± 1.0%; flowers: 45.8 ± 2.0%).'),(1883,'10.1080/10412905.2021.1966846','Comparative studies of essential oils composition and cytotoxic activity of <i>Valeriana jatamansi</i> Jones','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1966846',20,'https://openalex.org/W3195120756','The aim of this study was to investigate comparative essential oils (EOs) composition and cytotoxic activity of Valeriana jatamansi Jones, from wild growing samples at higher altitude and cultivated sample at lower altitude. Hydrodistilled EOs from the rhizomes of this herb were analyzed using Gas Chromatography with Flame Ionization Detector (GC-FID), Gas Chromatography/Mass Spectrometry (GC/MS), and Nuclear Magnetic Resonance (13C NMR). Thirty-six diverse metabolites were characterized in EOs samples accounting 68.5â88.2% of the total oils. The extracted EOs were found to be enriched in patchouli alcohol (7.6â70.5%), β-bisabolol (17.2â21.4%), maaliol (0.3â28.1%) and α-bulnesene (1.4â8.5%). The obtained EOs were further evaluated for cytotoxic activity against human lung carcinoma (A549) and human skin carcinoma (A431) cancer cells. Isolated component (patchouli alcohol) and extracted oils were represented good to moderate cytotoxic activity. These findings showed that EOs of these plants could be employed in the field of flavour, fragrance and pharmaceutical applications.'),(1884,'10.1080/10412905.2021.1966847','Characterization of the essential oil from <i>Annona acutiflora</i> and its nanoemulsion for the <i>Aedes aegypti</i> control','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1966847',10,'https://openalex.org/W3195330359','This work describes the chemical composition of the essential oil from Annona acutiflora and its larvicidal nanoemulsion. The volatile oil was extracted by hydrodistillation. The chemical characterization/quantification was performed by gas chromatography, revealing α-santalene, Bicyclogermacrene, and α-zingiberene as the major compounds. The nanoemulsion was prepared by low energy method. It was assayed against Aedes aegypti larvae, and in vitro anticholinesterase assay was carried out. This nanoemulsion presented a droplet size around 170 nm and PdI value around 0.170. The assay against larvae showed LC50 and LC90 values after 48 h, respectively, to 21.3 and 37.1 ppm. The anticholinesterase assays showed an IC50 value around 295.6 ppm. These results demonstrate that the method satisfactorily generated fine liquid oily nanodroplets dispersed in aqueous media. Moreover, to our knowledge, this is the first report of the chemical compositionfrom this species, being of great interest for new further integrative practices of vector control.'),(1885,'10.1080/10412905.2021.1975575','Extraction of Satureja Rechingeri volatile components through ultrasound-assisted and microwave-assisted extractions and comparison of the chemical composition with headspace solid-phase microextraction','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1975575',11,'https://openalex.org/W3200180387','The objective of the present work is comparison between various extraction methods for evaluation of the chemical composition and also extraction yield of theSatureja rechingeri. Efficient parameters of the Ultrasound-assisted extraction (UAE) and the Microwave-assisted extraction (MAE) processes were evaluated and optimized using RSM based on central composite design (CCD). For the approval the effect of various driving forces, chemical components of the essential oil were also determined through the HS-SPME. The highest yields of 4.408% and 4.352% were attained at optimum conditions for UAE and MAE, respectively. Statistical hypothesis testing was showed that there was no significant difference among predicted and experimental data (p > 0.05), proving high capability of models for prediction of the extraction of essential oil from S. rechingeri plant using UAE and MAE processes. Finally, GC/MS analysis technique coupled with aforementioned extraction methods was employed to determine the chemical composition of the extracted essential oils.'),(1886,'10.1080/10412905.2021.1975576','Effect on cell growth, viability and migration of geraniol and geraniol-containing essential oil from <i>Lippia alba</i> (Verbenaceae) on gastric carcinoma cells','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1975576',12,'https://openalex.org/W3196553839','Natural products used to treat cancer, or as leads for the development of preventive and co-adjuvant treatment strategies, are still a current approach. We studied the effect of essential oils from the medicinal plant Lippia alba on tumor cell lines and observed that geraniol-rich citral chemotype was the most effective, especially for breast and gastric carcinoma. Two main components of these essential oils, geraniol and limonene, were tested on gastric cancer cells, evidencing that geraniol was significantly more effective inducing cytotoxicity. The activity of geraniol on AGS cells was partially due to growth inhibition and we observed that some metastatic gastric cancer cells were also sensitive to this compound. The effect of geraniol on growth inhibition was not recovered by the addition of mevalonolactone, suggesting independence of isoprenylation. A partial inhibitory effect of geraniol was also observed on AGS migration, making it potentially effective to control invasive tumor behavior.'),(1887,'10.1080/10412905.2021.1975577','Volatile compounds and antifungal activity of <i>Dracocephalum moldavica</i> L. at different phenological stages','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1975577',11,'https://openalex.org/W3197465256','The present work aimed to study the essential oil (EO) variation of Dracocephalum moldavica L. under different phenological stages. The EO yield was highest in the flowering stage, followed by floral budding, fruit set, and vegetative stages. Twenty-three components in EOs were identified by GC-MS and quantified using GC-FID. Geranyl acetate (31â50 %), geranial (16â27 %), geraniol (12â13.4 %) and neral (10.67â17.30 %) were four main constituents. Antifungal assays of EO through mycelial growth inhibition percentages (MGI %) with four concentrations (0, 250, 500, and 750 µl/l) showed concentration-dependent responses. EOs showed the high potential of antifungal activity with ID50 values of (89â145), (27â88) and (183â339) µl/l and ID90 values of (667â1293), (509â1296), and (389â866) µl/l for Aspergillus niger, Penicillium expansum, and Trichoderma harzianum respectively. EO of D. moldavica showed considerable promise as a natural bio-preservative and bio-antifungal agent.'),(1888,'10.1080/10412905.2021.1975579','Comparative chemical profiling of <i>Zanthoxylum armatum</i> DC. from western Himalayan bioresource','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.1975579',15,'https://openalex.org/W3196658223','The objective of this work was to evaluate chemical composition of essential oils (EOs) extracted by hydrodistillation from different organs of the Zanthoxylum armatum (DC.) ie: leaves, aerial part (a bunch containing unriped fruits along with leaves), unripe and ripe fruits. The EOs metabolites were analyzed using GC/GC-MS (Gas Chromatography/ Gas Chromatography Mass Spectrometry) and NMR (Nuclear Magnetic Resonance). Highest yield was observed in ripe and unripe fruits (1.5% and 1.3%, respectively). Twenty seven different metabolites were characterized in all samples, representing (82.3â96.6%) of the total oils. Extracted EOs were dominated by monoterpenes (26.6â83.0%) and oxygenated (12.5â55.1%) monoterpene hydrocarbons with β-phellandrene (5.3â40.6%), sabinene (0.4â18.5%), β-myrcene (3.8â8.6%), limonene (5.5â12.5%), linalool (0.1â32.4%), terpinen-4-ol (3.0â12.9%), 1,8-cineole (0â11.6%), undecan-2-one (9.8â15.2%) and cis-sabinene hydrate (1.8â6.9%). Our findings revealed a very high quantitative and qualitative variation of EOs composition in among samples.'),(1889,'10.1080/10412905.2021.2008029','Variation in chemical composition and biological properties of two Tunisian <i>Eucalyptus</i> essential oils under three eco-friendly extraction techniques','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.2008029',9,'https://openalex.org/W4200039492','In this paper, three extraction methods: conventional hydrodistillation, microwave assisted hydrodistillation and supercritical carbon dioxide extraction, were applied to isolate essential oils from two Eucalyptus species. To our knowledge, it is the first study dealing with extraction and characterization of essential oils from E. intertexta and E. diversifolia from the south of Tunisia. A comparison between species in terms of yield, extraction time, and chemical composition of essential oils as well as their anti-inflammatory and anti-Alzheimer activities was done. The obtained yields varied from 0.88 to 8.35% depending on the species and extraction process. Chemical composition of essential oils was evaluated using gas chromatography and mass spectrometry. Eighty-six compounds were identified, whose major are 1,8-cineole (60.36%), and α-pinene (24.72%) in E. diversifolia EOs and 1,8-cineole (33.50%), caryophyllene oxide (21.51%) and p-cymene (21.29%) in E. intertexta EOs. Microwave assisted hydrodistillation was shown to be the faster compared to the other studied methods. Interesting activities were observed with E. diversifolia essential oils extracted by hydrodistillation (50% inhibition in anti-inflammatory test (5-lipoxygenase)) and by microwave assisted hydrodistillation (49% inhibition in anti-Alzheimer test (acetylcholinesterase)).'),(1890,'10.1080/10412905.2021.2022019','Biological fertilizers and superabsorbent polymer change biomass and volatile oil composition of <i>Ocimum ciliatum</i> Hornem','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2021.2022019',6,'https://openalex.org/W4206300605','NA'),(1891,'10.1080/10412905.2021.2022021','Chemical composition of essential oils from the leaves of <i>Mosiera bullata</i> (Britton &amp; P.Wilson), an unexplored Cuban endemic species','Journal of Essential Oil Research',2021,'https://doi.org/10.1080/10412905.2021.2022021',7,'https://openalex.org/W4200141819','Mosiera Small is a genus of Myrtaceae family with about forty species identified, including the Cuban endemic plant Mosiera bullata (Britton & P.Wilson) Bisse subsp. bullata. Mosiera species have been little investigated, and this is the first study analysing the composition of Mosiera bullata. Fresh leaf samples of M. bullata were collected from different locations near Santa Clara city, Cuba, and their essential oil was extracted. Using GC/MS, nineteen components (89.68% of the oil) were identified. The major compounds were found to be 1,8-cineole and eugenol, and a GC/FID method was analytically validated for their quantification. Chromatograms (GC/FID) of the sixteen samples studied were proposed as a fingerprint of the volatile composition of M. bullata leaves. Chemometric methods assured the reliability of the chromatographic fingerprinting. Therefore, in the present work is suggested, for the first time, a reliable and consistent chemical profile of M. bullata essential oil.'),(1892,'10.1080/10412905.2022.2029777','Phytochemical study and antioxidant activity of the most used medicinal and aromatic plants in Morocco','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2029777',19,'https://openalex.org/W4210721882','Genus Mentha is represented in Morocco by 10 species including hybrids. The species of this genus are used as herbal teas and condiments, due to their distinct aroma. In this study, infusions of the fresh aerial parts of three Mentha spp., commonly cultivated and used in Morocco, were evaluated for phenolic contents and antioxidant activity. Antioxidant capacity was assessed by three tests: scavenger activity by DPPH, FRAP (Ferric Reducing Antioxidant Power), and β-carotene bleaching methods. Infusions of M. piperita possess the best ability to reduce DPPH and chelate iron (IC50 = 7.50 ± 0.19 and 5.84 ± 0.36 μg/mL, respectively), while M. spicata shows great efficiency on inhibiting β-carotene (IC50 = 62.67 ± 0.01 μg/mL). The antioxidant capacity was significantly correlated with the total phenolic content and HPLC chromatographic analyses showed the predominance of phenolic acids, especially rosmarinic acid. Furthermore, by GC-MS analysis of Mentha spp. essential oils, eucalyptol, limonene, carvone, and pulegone were identified as predominant components.'),(1893,'10.1080/10412905.2022.2032421','Chemical composition and antimicrobial activity of the essential oil of <i>Abies cephalonica</i> Loudon from Mount Ainos (Kefalonia, Greece)','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2032421',7,'https://openalex.org/W4220999012','Abies cephalonica Loudon consists one of the three fir species occurring in Greece. The aim of this study was to evaluate the chemical composition of the essential oil (EO) from needles of A. cephalonica from Mt. Aenos (Kefalonia Island, Greece) and to investigate its antimicrobial activity. The EO was obtained by hydrodistillation and 68 constituents corresponding to 99.4% of the EO were identified by using GC-MS analysis. The major chemical category of the volatile compounds were the monoterpene hydrocarbons (63.9%), followed by oxygenated monoterpenes (20.2%). In particular, the main components were β-pinene (26.9%), bornyl acetate (12.5%), α-pinene (10.1%), camphene (9.2%), limonene (8.1%), γ-eudesmol (8.1%) and β-phellandrene (5.8%). To the best of our knowledge, the present study is the first research, reporting the phytochemical profile and the antimicrobial potential of the EO of A. cephalonica from this distinct geographic area.'),(1894,'10.1080/10412905.2022.2032424','Antibacterial activity of essential oils from Brazilian plants and their major constituents against foodborne pathogens and spoilage bacteria','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2032424',14,'https://openalex.org/W4210270818','This study aimed at determining antibacterial activities of three essential oils (EOs) and their major constituents against foodborne pathogenic bacteria and food spoilage ones. The EOs were tested by the broth microdilution method on 96-well microplates, followed by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) (µg/mL) determination. EOs from Psidium cattleianum Sabine, Cryptocarya aschersoniana Mez. and Ocotea dispersa Nees (Mez.) leaves showed strong antibacterial activity since their MIC and MBC values ranged between 20 and 250 µg/mL. Good activity of EOs under analysis can be mostly attributed to high concentrations of viridiflorol, limonene and α-eudesmol. EOs were analysed by gas chromatography-mass spectrometry (GC-MS) and gas chromatography with flame ionization detector (GC-FID). The three major commercial terpenes (viridiflorol, limonene and α-eudesmol) were evaluated individually and revealed MIC and MBC values between 20 and 62.5 µg/mL. The findings may serve as an important natural alternative to prevent bacterial growth in food products.'),(1895,'10.1080/10412905.2022.2036643','Chemical composition of essential oils isolated from leaves, twigs, roots and cones of Vietnamese <i>Keteleeria evelyniana</i> Mast','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2036643',6,'https://openalex.org/W4210538909','Keteleeria evelyniana Mast. is a species of conifer native to southern China, Laos and Vietnam. The species has been listed as vulnerable in Vietnam. Oil samples have been isolated from leaves, twigs, roots and cones, and analyzed by combination of GC(FID), GC-MS and 13C NMR. The composition of leaf oil, dominated by α-pinene (37.8%) and β-pinene (17.9%), varied substantially from that previously reported. Twig, cone and root oil compositions are reported for the first time. Twig oil contained mainly (E)-β-caryophyllene (25.4%) accompanied by α-pinene (15.9%), limonene (15.4%). (E)-β-caryophyllene (40.8%) was predominant in root oil, followed by α-Pinene (27.9%) and α-humulene (8.1%). Lastly, the composition of cone oil was characterized by a high content of α-pinene (58.8%) followed by β-pinene (22.0%). The occurrence of the diterpene iso-abienol (1.3%) could be noted. It could also be highlighted that the conformers βα and ββ of (E)-β-caryophyllene have been evidenced by 13C NMR spectroscopy.'),(1896,'10.1080/10412905.2022.2036644','Variation in essential oil constituents of coriander (<i>Coriandrum sativum</i> L.) germplasm across coriander growing regions in India','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2036644',11,'https://openalex.org/W4213352695','Variations in essential oil composition of 148 coriander (Coriandrum sativum L.) germplasms collected from various geographical locations in India were evaluated. Essential oil content was ranging from 0.04 to 0.27%. Eleven major compounds including α-pinene, camphene, β-pinene, myrcene, cymene, γ-terpinene, linalool, 4-allyl anisole, geraniol, anethole and geranyl acetate were detected in all the germplasm lines, with linalool as most abundant compound ranged from 16.59% to 96.69%. Another predominant compound observed was geranyl acetate, content of which ranged between 0.085 - 60.95%. Terpenoids consisting of α-pinene, β-pinene, camphene, myrcene, cymene and γ-terpinene accounted for up to 13.32% of essential oil. A significant negative correlation (râ0.811) was observed between linalool and geranyl acetate. Further, the germplasms were grouped in different classes as per major essential oil constituents. Cluster analysis was done using Wardâs method based on the value of linalool, α-pinene, γ-terpinene and geranyl acetate, resulted in 10 distinct groups of germplasms.'),(1897,'10.1080/10412905.2022.2036645','Productivity and essential oil quality of Himalayan Thyme (<i>Thymus linearis</i>Benth.) in relation to plant densities and drying methods','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2036645',7,'https://openalex.org/W4212917106','Thymus linearis (Benth. ex Benth), commonly known as Himalayan thyme, is used extensively in folk medicines, food-flavours due its extract and aromatic constituents. The impact of plant densities on dry herb productivity and quality essential oil of T. linearis, as well as the effect of drying procedures on essential oil quality, were investigated in this study. Six plant spacing and four drying methods were applied. The plant densities have significant effect on dry herb (p<0.1) and essential oil yield (p<0.01) of T. linearis. Total 28 compounds were identified, forming 95.1â98.9% of composition. Phenolic monoterpenoids (41.7â59.0%) and monoterpene hydrocarbons (29.8â47.5%); with thymol (36.6â53.9%), γ-terpinene (17.7â24.1%) and p-cymene (3.8â17.0%) were the major constituents. The yield of dry herb and essential oil in thyme influenced by plant densities. Results showed that narrower spacing produces higher grain and quality essential oils in thyme as compared to wider spacing.'),(1898,'10.1080/10412905.2022.2050955','Eugenol, obtained from the bioassay-guided fractionation of <i>Coriandrum sativum</i> essential oil, displayed antioxidant effect in deep-frying procedure of sunflower oil and improved sensory properties of fried products, <i>Caijiao</i>','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2050955',6,'https://openalex.org/W4220886804','The deep-frying procedure of Caijiao in sunflower oil (SFO) needs natural antioxidants. In the present study, the essential oil of Coriandrum sativum (CSEO) was added into SFO at 0.16 g/kg to prepare SFO sample. During the deep-frying procedure of Caijiao, total polar compounds (TPC), thiobarbituric acid (TBA), conjugated dienes (CD), conjugated trienes (CT), polymers, viscosity and b* were prominently inhibited, together with the obvious reduction of L* (p < 0.01 or p < 0.05). The sensory attributes of Caijiao were also obviously improved (p < 0.01 or p < 0.05). In the meantime, the addition of synthetic antioxidants to SFO, such as TBHQ, BHA and BHT, didn<apos;>t display effective antioxidant effect. After the bioassay-guided fractionation, the antioxidant effect of CSEO was attributed to one of its natural products, eugenol. The research and development of eugenol for effective natural antioxidants is of much importance for the whole food industry.'),(1899,'10.1080/10412905.2022.2058633','Phytochemical study and pharmaceutical properties of essential oils and organic extracts of two <i>Eucalyptus</i> species: <i>E. stricklandii</i> Maiden and <i>E. brevifolia</i> F.Muell','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2058633',3,'https://openalex.org/W4223492398','Essential oils and solvent extracts of E. brevifolia F.M and E. strickalndii M. were screened for their chemical composition, and biological activities. 39 compounds were identified in, E. brevifolia F. M. EOs, whereas 41 volatile compounds were identified in E. stricklandii M. EOs. The organic extracts were rich on polyphenols and tannins. The IC50 of the ME of E. stricklandii M. using DPPH· assay was 4.4 ± 0.2 µg/mL. Concerning AChE, the aqueous extract of E. brevifolia F.M. exhibited the highest IC50 value 10.0 ± 0.0 µg/mL. Regarding the anti-inflammatory capacity, E. brevifolia F.M. EOs and E. stricklandii M. ME showed the best IC50 (7.3 µg/mL and 9.7 µg/mL) against the inhibition of 15-LOX. Both plants exhibited a good activity against gram-negative bacteria. Finally, E. stricklandii M. ME was the best cytotoxic extract against HCT116 and K562 with IC50s of 18.0 ± 0.1 µg/mL and 1.8 ± 0.0 µg/mL.'),(1900,'10.1080/10412905.2022.2058634','Variability in chemical composition and antibacterial activity of <i>Salvia majdae</i> essential oil under various extraction techniques','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2058634',8,'https://openalex.org/W4226425668','Salvia majdae (Lamiaceae) is an aromatic herb of pharmaceutical interest in Iran due to its several biological properties. In the present study, we studied the chemical composition and antibacterial activity of S. majdae essential oil (EO) by comparing several extraction methods, including hydrodistillation (HD), steam distillation (SD), ultrasound-assisted hydrodistillation (UAHD), microwave-assisted hydrodistillation (MAHD) and ohmic-assisted hydrodistillation (OAHD). The major EOs compounds obtained with all methods included linalool (39.4â45.7%) and camphor (30.9â34.3%). The highest EO yield was obtained using HD and MAHD, with 9 and 5% (w/w), respectively. The shortest extraction time (20 Min) was obtained using MAHD. The antibacterial activity of S. majdae EOs was evaluated by the minimum inhibitory concentration (MIC) method on a panel of Gram-positive (Bacillus subtilis, Staphylococcus aureus and Curtobacterium flaccumfaciens) and Gram-negative (Agrobacterium tumefaciens, Xanthomonas citri and Escherichia coli) bacteria. Notably, the EO obtained by HD demonstrated the highest antibacterial activity.'),(1901,'10.1080/10412905.2022.2058635','Seasonal variations during two years in the essential oil of <i>Lippia dulcis</i> Trevir., an exotic aromatic of the Amazon','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2058635',2,'https://openalex.org/W4226062320','Lippia dulcis Trevir. (Verbenaceae) is an aromatic plant occurring in the Amazon that has leaves and flowers with a sweet taste. The objective of this study was to evaluate the influence of seasonal variation during two consecutive years on the content and chemical composition of the essential oil (EO) of L. dulcis leaves. The EO content and chemical composition were influenced by precipitation, temperature, and plant age. The EO content ranged from .1 to .5%. The chemical profile of the EO did not vary significantly among seasons. The main constituents identified were the oxygenated bisabolane-type sesquiterpenes epi-α-bisabolol and hernandulcin. The highest concentration of hernandulcin was observed in the dry period, characterized by mild temperatures and the juvenile stage of plant growth. The highest concentrations of epi-α-bisabolol were observed in the hottest and wettest season of each year.'),(1902,'10.1080/10412905.2022.2063957','Chemical investigation, quality assessment, and antimicrobial activity of davana (<i>Artemisia pallens</i>Wall. ex DC) essential oil collected from different locations in India','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2063957',7,'https://openalex.org/W4224039049','Artemisia pallens Wall. ex DC, commonly known as davana, is cultivated in India for extraction of its essential oil (DO). In this study, DO collected from thirteen locations (DO1-DO13) and those extracted from six different phenophases and different plant parts were investigated using GC-FID and GC-MS. Altogether, 84 constituents were identified, forming 81.0â96.2% of the total oil composition. Major components of the oils were cis-davanone (17.4â65.1%), bicyclogermacrene (4.0â22.0%), cis-methyl jasmonate (0.4â8.5%), β-eudesmol (0.3â6.6%), davana ether isomer (0.5â6.1%), trans-ethyl cinnamate (1.4â6.1%), and germacrene D (0.1â4.7%). Among all tested oils, the DO10, having low cis-davanone content (27.5%), was found more potent against test microorganisms. The oils collected from different locations showed variations in their physical properties, chemical composition, and antimicrobial activity. Based on the yield and cis-davanone content, the flower bud and full-flowering stages could be suitable for harvesting good quality oil in north Indian plains.'),(1903,'10.1080/10412905.2022.2066211','Chemical constituent and bioactivity of <i>Valeriana officinalis</i> L. root essential oil using neutral cellulase-assisted steam distillation','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2066211',6,'https://openalex.org/W4225009738','Neutral cellulase-assisted steam distillation (NCSD) was developed to extract essential oil from Valeriana officinalis L. root, and a single-factor experiment was designed to optimize the NCSD. Chemical composition was subsequently compared between Valeriana officinalis L. root essential oil (VORO) extracted by NCSD and conventional steam distillation (SD). Results show that the highest yield of VORO extracted by NCSD was 68.09% higher than that extracted by SD. Results of antibacterial activity indicate that the two VOROs had an equally strong antibacterial activity of Bacillus subtilis, Staphylococcus aureus, and Escherichia coli with minimum inhibitory concentration (MIC) of 0.88, 1.75, and 3.50 mg/mL, respectively. Both VOROs also showed sufficiently high antioxidant and anti-dust mite abilities. The VORO concentration higher than 0.35 mg/mL was regarded as an A-grade dust mite repellent and B-grade miticide. This study has emphasized the significances of VORO in the food and textile industries as a potential additive.'),(1904,'10.1080/10412905.2022.2066212','Essential oil composition, antioxidant and antibacterial activity against <i>Vibrio parahaemolyticus</i> from five Lamiaceae species','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2066212',7,'https://openalex.org/W4224307305','In peneide shrimp, diseases caused by Vibrio species are the source of serious economic losses worldwide. Essential oils from Lamiaceae species are sources of bioactives for aquaculture, with potential antimicrobial and antioxidant activity. The aim was to investigate the chemical composition, antimicrobial activity and antioxidant effects of essential oils from five species of Lamiaceae against Vibrio parahaemolyticus. Approximately forty-eight components were identified and quantified by gas chromatography-mass spectrometry (GC-MS) and flame ionization detection (GC-FID). The predominant compounds were linalool (0.2â74.2%), eugenol (47.5%), 1,8-cineole (0.2â44.5%), camphor (0.2â31.2%), sabinene (0.4-13-4%), β-pinene (0.1â8.5%), thymol (51.0%) and p-cymene (1.7â26.4%). The essential oils presented values of Minimum Inhibitory Concentration and Bactericidal between 5.0â0.313 mg mLâ1 and effective antioxidant potential (IC50: 0.11â16.15 mg mLâ1). Its main components have potential application in scavenging free radicals, inhibiting bacterial growth, important for the food and aquaculture industry.'),(1905,'10.1080/10412905.2022.2067255','Histochemistry, chemical composition and antioxidant activity of<i>Citrus aurantium</i>L. essential oil during leaf development','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2067255',5,'https://openalex.org/W4224251630','Essential toils are important natural products of aromatic plants, which are mostly biosynthesized and accumulated in secretory cavities. In this study, the impact of leaf developmental stages was investigated on secretory structure, chemical composition and antioxidant activity of Citrus aurantium essential oil. The secretory cavity of young leaf had more essential oil droplets than that of mature leaf which indicated that the young leaf constitutes a mass production of essential oil in Citrus aurantium leaf. In fact, the young leaves exhibited the highest essential oil yield (0.77%), followed by intermediate (0.50%) and mature (0.25%) leaves. The major constituent of the leaf essential oil composition was sabinene (33.17â44.83%), followed by E-β-ocimene (7.57â8.21%) in young and intermediate leaves but by δ-3-Carene (12.81%) in mature leaves. The antioxidant activities of Citrus aurantium essential oil at different leaf stages were evaluated by using DPPH radical scavenging, reducing power and β-carotene-linoleic acid bleaching assays. Independently of leaf development, Citrus aurantium essential oil showed a strong capacity to reduce iron while it had a low ability to scavenge DPPH radicals and to bleach β-carotene.'),(1906,'10.1080/10412905.2022.2067256','Chemical composition and effects of <i>Ocimum gratissimum</i> essential oil (OGEO) on the expression of mRNA for antioxidant enzymes during <i>in vitro</i> culture of bovine ovarian secondary follicles','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2067256',0,'https://openalex.org/W4225401202','This study analyzed the chemical composition of OGEO and its effects on growth, viability, antrum formation and mRNA expression for superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and peroxiredoxin 6 (Prdx6) in bovine secondary follicles cultured in vitro. The follicles were cultured in TCM-199+ alone or supplemented with 0.125, 0.25 and 0.50% OGEO for 18 days. Follicle diameters, viability, antrum formation and the levels of mRNA for SOD, CAT, GPX1 and PRDX6 in cultured follicles were evaluated. The results showed that the main components of OGEO were Eugenol and 1.8-Cineol. The follicles cultured with OGEO maintained morphology, viability and growth similar to the control group. Interestingly, follicles cultured with 0.5% or 0.25% OGEO had, respectively, higher levels of mRNAs for PRDX6 and CAT than those cultured in control medium. In conclusion, OGEO increases mRNA expression for PRDX6 and CAT in bovine secondary follicles cultured in vitro.'),(1907,'10.1080/10412905.2022.2072962','Chemical profile, antibacterial, antioxidant and insecticidal properties of the essential oil from <i>Tetraclinis articulata</i> (Vahl) masters cones','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2072962',11,'https://openalex.org/W4280543417','The aim of the present work was to study the chemical composition and to evaluate, in vitro, the antibacterial, antioxidant and insecticidal properties of the essential oil obtained from Tetraclinis articulata (Vahl) (Cupressaceae) masters cones collected from the eastern region of Morocco. GC-MS and GC-FID analyses of essential oil of T. articulata cones (TA-EO) led to the characterization of 57 components, representing 91.1% of the total volatile fraction of TA-EO. The TA-EO had a bactericidal effect against all clinical multidrug bacteria. Furthermore, TA-EO displayed strong antioxidant capacity against DPPH radical. Fumigation bioassays showed that TA-EO exhibits strong toxic effect against Sitophilus granarius and Tribolium confusum. The results obtained from this study indicate that essential oil of T. articulata masters cones is promising as a source of natural antioxidant, insecticide and antibiotic can be used in the pharmaceutical and agriculture fields.'),(1908,'10.1080/10412905.2022.2074556','Chemical profile, antioxidant and antimicrobial effects of essential oil from the Moroccan endemic plant cladanthus scariosus (L.)','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2074556',5,'https://openalex.org/W4281396480','In this study, chemical profile, antioxidant potential and antimicrobial interactions with conventional antimicrobials of essential oil (EO) isolated from Cladanthus scariosus aerial parts were investigated. The EO was analyzed by GC-MS (Gas Chromatography-Mass spectrometry). Forty-three components representing 98.7% of the oil were identified. The main components were o-cymene, caryophyllene oxide, γ-terpinene and α-sabinene. Furthermore, the antioxidant and antimicrobial activities against ten bacteria and two Candida strains were assessed. The results showed an interesting antioxidant effect with IC50 of 1.04 ± 0.04 mg/mL, 0.55 ± 0.01 mg/mL and 0.36 ± 0.14 mg/mL, respectively, for DPPH (2,2-Diphenyl-1-Picrylhydrazyl), FRAP (Ferric-Reducing-Ability-Power), and ABTS (2-2âazinobis-3-ethylbenzothiazoline-6-sulphonate) methods. The EO exhibited a strong antimicrobial activity, especially against Methicillin-resistant Staphylococcus aureus and Candida glabrata. In combination with antimicrobials, the studied EO revealed a high synergism effect in reducing gentamicin MICs of bacterial strains by 128- to 256-fold and by 2- to 8-fold Fluconazole MICs against Candida strains.'),(1909,'10.1080/10412905.2022.2075478','Chemical composition and larvicidal activity of <i>Ocimum</i> species essential oils from the south of the Paranaense forest (Argentine) against <i>Aedes aegypti</i> (Diptera: Culicidae) larvae','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2075478',3,'https://openalex.org/W4280538665','Aedes aegypti plays a predominant role in the transmission of a variety of diseases, such as yellow fever, dengue fever, malaria, Zika and Chikungunya disease. The reduction of chemicals available for vector control due to the increase in mosquito resistance to insecticides and their negative impact on the human health and the environment have driven the focus of the problem towards the identification and evaluation of sustainable alternatives to synthetic insecticides. The essential oils from the leaves of Ocimum campechianum, Ocimum ovatum, and Ocimum selloi were analyzed by GC/MS and GC/FID and investigated for its larvicidal activity against A. aegypti larvae. In the chromatographic analyses showed that the main compounds were elemicin (22.8%), methyl eugenol (33.4%), and methyl eugenol (46.5%), respectively. The susceptibility tested on essential oils was performed according to the World Health Organization protocol. The highest larvicidal potential was displayed by O. ovatum, followed by O. campechianum and O. selloi, with LC50 values of 47.5, 95.5 and 141.2 ppm, respectively. The rapid and efficient larvicidal activity of these three essential oils led us to consider these results as promising for the search of a potentially effective earth-friendly larvicide against the A. aegypti vector.'),(1910,'10.1080/10412905.2022.2075479','Phytochemical profile and biological effects of essential oils from three <i>Inula</i> species grown in Tunisia','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2075479',7,'https://openalex.org/W4281490844','This work investigated the chemical composition of essential oils (EOs) obtained from the aerial parts of three Inula species of the Tunisian flora as well as their biological properties. Inula viscosa essential oil (IVEO) contained mainly α-costic acid (65.4%). The EOs of Inula graveolens (IGEO) and Inula crithmoides (ICEO) were characterized by high contents of p-cymene derivatives while ICEO stands out by high levels of modheph-2-ene (16.5%) and tiglic esters (14.1%). Moreover, a notable antioxidant power was proved by the ORAC test for the three EOs. Finally, the cytotoxic activity was evaluated on two healthy cell lines (CCD45-SK, HUVECs) and two cancer cell lines (HepG-2, MCF-7) and it appeared that the EOs were particularly effective on MCF-7 human breast cancer cells with LC50 equal to 79, 16, and 63 µg. mLâ1 for IVEO, IGEO, and ICEO, respectively.'),(1911,'10.1080/10412905.2022.2091673','Essential oil of <i>Origanum vulgare</i>, its nanoemulsion and bioactive monoterpenes as eco-friendly novel green pesticides for controlling <i>Aedes aegypti</i>, the common vector of Dengue virus','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2091673',12,'https://openalex.org/W4283807658','Essential oil (EO) of Origanum vulgare L. was hydrodistilled and analysed using gas chromatographyâflame ionization detection and gas chromatographyâmass spectrometry. The monoterpenes, carvacrol (61.2%), γ-terpinene (9.6%), thymol (8.3%), and p-cymene (5.7%) were identified. Oil-in-water nanoemulsion was prepared and characterized from the EO through a green procedure. Botanicals had a remarkable mosquitocidal and effectively inhibited acetylcholinesterase activity of Aedes aegypti. The nanoemulsion at 40 µg/ml caused 100% adult and larval mortality after 12 h. At 80 µg/ml, percentage mortality caused by EO products ranged between 55.11-100% for larvae, and 63.0 -100%. for adults After 24 h exposure, LC50\'s ranged between 13.2 and 75.7 µg/ml against larvae, and between 10.1 and 36.0 µg/ml against adults. The lethal time (LT50) decreased with nanoemulsion, EO and carvacrol. Test products were safe towards the non-target aquatic species, Gambusia affinis and Diplonychus indicus. Results recommend test botanicals as natural alternatives to control Ae. aegypti.'),(1912,'10.1080/10412905.2022.2103043','Chemical and antibacterial properties of <i>Baccharis dracunculifolia</i> DC essential oils from different regions of Brazil','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2103043',6,'https://openalex.org/W4294071812','This study aimed to evaluate the chemical and antibacterial properties of the essential oil of B. dracunculifolia from three regions of Brazil: Midwest, Southeast and South region. The major compounds of essential oil from Midwest region were (E)-nerolidol (28.15%) and spathulenol (17.68%), both oxygenated sesquiterpenes. And the major compounds of essential oils from Southeast and South regions were (E)-nerolidol (12.75â13.95%), bicyclogermacrene (10.76â14.21%) and limonene (10.49â19.36%). The three essential oils showed antibacterial activity for both Gram-positive and Gram-negative bacteria tested, with MIC values from 0.03 to 0.15 mg/mL and MBC values from 0.05 to 0.30 mg/mL. The B. dracunculifolia essential oil from the Midwest region of Brazil presented higher values of oxygenated sesquiterpenes and was more effective on all tested bacterial strains, with lower and statistically significant MBC values, compared to the oils from the Southeast and South regions of Brazil'),(1913,'10.1080/10412905.2022.2103190','Agronomic traits and essential oil profiles of <i>Humulus lupulus</i> L. cultivated in southern Italy','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2103190',10,'https://openalex.org/W4287877993','Humulus lupulus L. is a dioecious herbaceous perennial plant with a climbing habit, whose female inflorescences, commonly known as cones, produce and accumulate bitter substances and essential oils. The present study aimed to assess the adaptability of some American hop varieties (Cascade, Chinook, and Comet) in the Mediterranean environment of the Calabria region (Italy) through the evaluation of the morpho-biological and productive characteristics and the characterization of the aromatic traits of the inflorescences. Comet proved to be the most productive variety, while Chinook the earliest. Essential oils obtained by hydrdistillation were analysed by GC-FID and GC-MS. Myrcene, β-caryphyllene and α-humulene were the main components. The combination of morphological traits and the aromatic profiles could be adopted as tools to discriminate varieties. Comet was the most productive variety, while Chinook emerged as the earliest one. Concernng the essential oils Cascade and Comet showed similar profiles, Chinnok was different especially for the sesquiterpenes content.'),(1914,'10.1080/10412905.2022.2103596','Seasonal variation in the essential oil of <i>Satureja kitaibelii</i> determines chemotypes','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2103596',8,'https://openalex.org/W4288080855','The aim of the present study was a chemical and chemometric analysis of Satureja kitaibelii Wierzb. ex Heuff. essential oil during different stages of development, with emphasis on chemotaxonomy. The most abundant compound class in the S. kitaibelii oil during examined phenological stages was oxygenated monoterpenes (21.3â61.2%), except vegetative stage, in which monoterpene hydrocarbons are dominant (51.1%). Geraniol, limonene, p-cymene and borneol are the most abundant compounds of essential oil during different stages of development. The highest variation in content, during plant development, was shown by the most dominant component, geraniol (coefficient of variation 112.3%). Chemometric analysis indicated two chemotypes: limonene/p-cymene/geraniol and limonene/p-cymene/borneol. We are of the opinion that the three most abundant EO components should determine the chemotype. Our results lead to the conclusion that essential oil isolated from the plant in 1 month should not be used to determine the chemotype.'),(1915,'10.1080/10412905.2022.2104393','Bioactivity of<i>Cupressus sempervirens</i>and<i>Cupressus lusitanica</i>leaf essential oils on<i>Colletotrichum fructicola</i>','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2104393',9,'https://openalex.org/W4286669422','The present work aimed to study the chemical composition and bioactivity of the leaf essential oil of Cupressus sempervirens L. and Cupressus lusitanica Mill. (Cupressaceae) on mycelial growth and germination of Colletotrichum fructicola conidia at the essential oil concentrations of 0.1, 0.5, 1.0, 1.5, and 2.0 µL·mLâ1. The essential oil of C. sempervirens presented β-thujene as the major compound (31.4 wt.%), whereas C. lusitanica essential oil was composed mainly of α-pinene (22.7 wt.%). The bioactivity tests showed that both essential oils were ineffective in controlling adult C. fructicola individuals at the tested doses. However, antifungal activity of the oils against germination of the conidia was observed, in which C. sempervirens and C. lusitanica essential oils inhibited 50 % and 38 % of C. fructicola conidia germination at the concentration of 2 µL·mLâ1. Morphological alterations of hyphae were also observed after exposure to C. sempervirens essential oil at the dose of 2 µL·mLâ1.'),(1916,'10.1080/10412905.2022.2107100','Preparation, characterization, and antimicrobial activity of cinnamon essential oil and cinnamaldehyde nanoemulsions','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2107100',21,'https://openalex.org/W4289945032','Cinnamomum verum essential oil and its main component, cinnamaldehyde, were incorporated into nanoemulsions to improve their stability and activity. Oil-in-water (O/W) nanoemulsions were prepared using the high-energy ultra-sonication method. Cinnamon oil nanoemulsion exhibited a more vigorous DPPH radical scavenging activity (IC50 = 1.81 mg/L) than the standard α-tocopherol (IC50 = 9.16 mg/L). Cinnamaldehyde nanoemulsion exhibited the highest antibacterial action against Salmonella typhimurium and Staphylococcus aureus (MIC = 175 and 150 mg/L, respectively). It was also displayed the highest inhibition against Candida albicans (EC50 = 19.92 mg/L). Cinnamaldehyde nanoemulsion was the most active against mycelial growth of Aspergillus flavus and A. niger (EC50 = 38.20 and 134.80 mg/L, respectively). It also presented the highest activity against spore germination. This study describes antimicrobials and antioxidants based on nanoemulsions made from natural products that can be used to treat microbial infections.'),(1917,'10.1080/10412905.2022.2107101','Cytotoxic activity and antioxidant effects of<i>Origanum onites</i>essential oil and its two major contents, carvacrol and<i>p</i>-cymene on human colorectal (HCT116) and hepatocelluler carcinoma (HepG2) cell lines','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2107101',21,'https://openalex.org/W4290803812','Origanum onites L. (O. onites) is one of the cultivated Origanum species in Turkey. The aim of this study was to determine the cytotoxicity and cellular antioxidant effects of O. onites essential oil, carvacrol and p-cymene on HCT116 and HepG2 cells. O. onites essential oil components were analyzed by GC/MS and GC/FID. Cytotoxicity was analyzed via the MTT assay in HCT116 and HepG2 cells. Cellular antioxidant activities of O. onites essential oil, carvacrol and p-cymene were determined with DCFH-DA method. GC/MS analysis identified carvacrol (%78.4) as the main constituent of O. onites essential oil. 400 µg/ml concentration of O. onites essential oil, carvacrol and p-cymene were found to be active against HCT116 and HepG2 cells. Also, carvacrol showed higher cellular antioxidant activity than O. onites essential oil and p-cymene. We conclude that O. onites essential oil and carvacrol may be a candidate for pharmaceutical products in treatment of cancer.'),(1918,'10.1080/10412905.2022.2107102','Effect of different extraction techniques on the composition of essential oil isolated from fennel (<i>Foeniculum vulgare</i> Mill.) rhizome','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2107102',18,'https://openalex.org/W4290018092','The aim of the presented work was to compare the efficiency of innovative (solvent-free microwave extraction, microwave-assisted hydrodistillation and supercritical CO2 extraction) extraction techniques vs. conventional Clevenger hydrodistillation of essential oil (EO) from poorly studied fennel rhizome. It was found that innovative extraction techniques enhance the EOs/extracts isolation, save time and exclude solvents providing green ecologically technologies. Solvent-free microwave extraction proved to be the most efficient with limonene and (E)-anethole as dominant compounds in concentration of 12.34 ± 0.31 and 35.63 ± 1.51 mg/ml, respectively, as well as with the largest number of isolated and identified compounds. Primary aroma compounds were identified by two direct headspace techniques â static headspace extraction (HSS) and headspace solid phase microextraction (HS-SPME) confirming limonene and (E)-anethole as dominant compounds in primary aroma mixture with 53.7 ± 2.02% and 30.9 ± 1.43% (HSS) and 69.8 ± 2.80% and 13.1 ± 0.11% (HS-SPME), respectively.'),(1919,'10.1080/10412905.2022.2107103','An <i>in vitro</i> study of <i>the origanum minutiflorum</i> O. Schwarz &amp; P. H. Davis and <i>Coriandrum sativum</i> L. essential oils as chronic tonsillitis therapeutics: antibacterial, antibiofilm, antioxidant, and cytotoxic activities','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2107103',7,'https://openalex.org/W4290017979','The chemical composition and biological activity of essential oils (EOs) from leaves of Origanum minutiflorum O. Schwarz & P.H.Davis, and seeds of Coriandrum sativum L. were investigated. Chemical analyses of EOs were performed and the major components were carvacrol (81.5%) and linalool (69.6%), respectively. The antimicrobial activity was assessed against several bacteria originating from the tonsillar tissue. Activities of EOs against Staphylococcus aureus biofilm were investigated, as well as the effect of the mixture of these EOs and antibiotics against the pathogen. The antioxidant activity of both EOs was determined by TBARS assay, and examined wild oregano EO showed better activity. Also, cytotoxicity of EOs was evaluated in vitro and both EOs showed potential to inhibit further proliferation of tumor cells. This study reported for the first time the effects of EOs on chronic tonsillitis causative pathogens, supporting their role as a natural bioactive therapeutic agent with possible antimicrobial applications.'),(1920,'10.1080/10412905.2022.2109767','Chemical composition, <i>in vitro</i> antifungal activity, DFT, molecular docking and molecular dynamics simulation studies of the essential oil from <i>Anvillea gracinii</i> subsp. <i>radiata</i> (Coss. &amp; Durieu) Anderb','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2109767',7,'https://openalex.org/W4290631908','This study describes the chemical composition and the in vitro antifungal activity of the essential oil (EO) of Anvillea gracinii subsp. radiata aerial parts against three phytopathogenic using the poisoned food (PF) and the volatile assay (VA) techniques. Gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) allowed the identification of 35 compounds which cis 8-acetoxychrysantenyl acetate (cis8ACA) (30.8%), cis-chrysanthenyl acetate (15.5%), 6-oxocyclonerolidol (14.9%) and Ï-cadinol (7.4%) are the main constituents. In VA test, the minimum inhibitory concentrations (MIC) are 0.50 µL/mL for B. cinerea and P. expansum and 1.00 µL/mL for R. stolonifer, but they are 0.125 µL/mL for B. cinerea and 0.25 µL/mL for other fungi using PF technique. Molecular docking and molecular dynamics (MD) simulations revealed that cis8ACA has the smallest docking energy (-8.9 kcal.mol-1) indicating its high affinity to bind to the active site of the C14DM thereby forming a stable cis8ACA -C14DM complex.'),(1921,'10.1080/10412905.2022.2115568','Investigation of essential oil and water-soluble extract obtained by steam distillation from <i>Acacia mearnsii</i> flowers','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2115568',3,'https://openalex.org/W4298144251','This work aimed to obtain and investigate the properties and composition of extracts from flowers of Acacia mearnsii; this tree is widely cultivated because the bark is used as a raw material for various industry segments, but the flowers are not yet explored. The essential oil was evaluated by GC/FID, GC/MS, and GC/O. The antioxidant activity (DPPH and phosphomolybdenum methods) and chemical composition were investigated for a water-soluble extract, a by-product of the extraction process. 85.8% of the compounds present in the essential oil were identified, 8-heptadecene being the major compound. The main scents detected by the olfactory analysis were roast nutty, coffee, sweet, and floral. The water-soluble extract showed antioxidant activity that may be related to phenolic compounds. Results obtained from the LC-qTOF/MS analysis have shown that 25 likely flavonoids, such as naringenin, myricetin, quercetin, and rutin are present in the extract.'),(1922,'10.1080/10412905.2022.2115569','Chemical composition and acaricidal activity of the essential oils of <i>Piper marginatum</i> and <i>Piper callosum</i> collected in the Amazon region','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2115569',12,'https://openalex.org/W4298144279','The objective of this study was to evaluate the chemical profile and acaricidal activity against the mite Suidasia pontifica of the essential oils from leaves of Piper marginatum Jacq and aerial parts (branches, leaves, and inflorescences) of Piper callosum Ruiz & Pav. From the aerial parts (branches, leaves and inflorescences) of P. callosum, three different essential oils were extracted with variations in the contents of their chemical constituents. The major compounds in the essential oil of P. marginatum were δ-3-carene and (E)-β-ocimene, while safrole was the predominant compound in the essential oils of P. callosum. Concentrations of 4 μL/L of the essential oil of P. marginatum and 2 μL/L of the essential oil of P. callosum killed all the mites tested after 72 h of exposure. The 50% lethal concentration ranged from 1.19 to 2.16 µl/L air for P. marginatum and from 1.22 to 3.44 µl/L air for P. callosum.'),(1923,'10.1080/10412905.2022.2115570','Evaluation of the antioxidant activity of the essential oils from <i>Cantinoa carpinifolia</i> (Benth.) and <i>Lippia origanoides</i> (Kunth.) by various methods','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2115570',7,'https://openalex.org/W4298144182','The essential oils from Cantinoa carpinifolia (Benth.) and Lippia origanoides (Kunth.) were obtained by hydrodistillation. The constituents were determined by GC-MS and GC-FID. The antioxidant activities were evaluated by the ABTS, DPPH and hydroxyl radicals, phosphomolybdenum complex, reducing power, β-carotene/linoleic acid and the TBARS methods. Analysis of variance and the ScottâKnott test of the means at 5% were performed. The principal constituents in the essential oil from C.carpinifolia were α-thujone (32.15%) and β-thujone (22.22%), whereas carvacrol (41.51%), p-cymene (18.36%) and γ-terpinene (17.03%) were obtained from L.origanoides. The respective IC50 for the essential oils from C. carpinifolia and L.origanoides in the ABTS tests were >1000 and 110 µg mLâ1; DPPH (110 and >1000 µg mLâ1), hydroxyl (636 and 484 µg mLâ1), β-carotene (>2000 and 215 µg mLâ1) and TBARS (778 and 527µg mLâ1). The L. origanoides essential oil was the most effective antioxidant.'),(1924,'10.1080/10412905.2022.2118878','Potential anti-inflammatory activity of the <i>Anastatica hierochuntica essential oil</i>','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2118878',6,'https://openalex.org/W4294685847','The aims of this study were to evaluate the anti-inflammatory activity and the possible anti-inflammatory mechanisms of Anastatica hierochuntica essential oil (EOAH). The essential oils were obtained by hydrodistillation of the aerial parts of the plant, and analyzed using gas chromatography and mass spectrometry (GC/MS). Their anti-inflammatory activity was evaluated using classical model of inflammation (carrageenan-induced paw edema and peritonitis). Nitric oxide radical-scavenging activity and lipid peroxidation were determined to assess the antioxidant activity of the essential oil. The EOAH mainly comprised Cuminaldehyde (33.8%), trans-β-Caryophyllene (32.5%), and Linalool (8.2%). EOAH significantly reduced edema, peritonitis, myeloperoxidase activity, and NOx-peritoneal lavage concentration induced by carrageenan. In addition, nitric oxide radical generated from sodium nitroprusside was significantly inhibited by the essential oil. Furthermore, EOAH was able to prevent Fe+2- or Fe+2 plus H2O2-induced lipid peroxidation. In conclusion, the EOAH exerts anti-inflammatory activity that could be related to its antioxidant capacity.'),(1925,'10.1080/10412905.2022.2118879','Synergized potential, insecticidal and repellent activity of essential oils from two <i>Rhododendron</i> species against three stored product insects','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2118879',13,'https://openalex.org/W4295007872','NA'),(1926,'10.1080/10412905.2022.2118880','Anti-inflammatory and anti-allodynic activities in mice of the essential oil and desmethylisoencecalin from <i>Zinnia grandiflora</i> Nuttall','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2118880',0,'https://openalex.org/W4297880012','Zinnia grandiflora (Asteraceae) is used to alleviate several painful disorders. The effects of an essential oil prepared by hydrodistillation from Z. grandiflora (EOZ) and its major compound on neuropathic pain, allodynia, and inflammation in mice were assessed. Headspace-solid phase microextraction analysis of an aqueous extract was also carried out. GC-MS analyses of all volatiles revealed that germacrene D (13.24%) and desmethylisoencecalin (DME) (13.24%) were the most abundant compounds. EOZ was effective in reducing inflammation and allodynia in mice. EOZ (300 mg/paw) reverted tactile allodynia more effectively than gabapentin (100 μg/paw). DME (0.1â10 µg/paw) responses in the carrageenan model were concentration-dependent; the maximum effect was observed at 10 µg/paw, like that of diclofenac (30 μg/paw). In the spinal nerve ligation model, DME (0.1â10 μg/paw) exerted a concentration-dependent anti-allodynic action; its effect was better than that of gabapentin. A method to quantify zinagrandinolide E in the crude drug was developed and validated.'),(1927,'10.1080/10412905.2022.2147592','The essential oil compositions of two <i>Eucalyptus</i> sp. (<i>E. camaldulensis D</i>ehnh. and <i>E. torquata L</i>uehm.) naturalized to Cyprus','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2147592',10,'https://openalex.org/W4309834010','ABSTRACT The genus Eucalyptus belonging to the Myrtaceae family, consists of tall, evergreen trees with leathery leaves. They are indigenous to Australia and contain about 900 species and subspecies. One important use is production of essential oils, which are valuable in both medicinal and pharmaceutical industries. There are about 62 species of Eucalyptus naturalized to Cyprus including E. camaldulensis and E. torquata. The essential oil constituents of leaves of these two species of Eucalyptus collected from Northern Cyprus were isolated by hydro-distillation and analyzed by GC and GC/MS, simultaneously. E. camaldulensis oil yield was higher (2.4%), and major compounds identified were α-phellandrene (10.3%) and β-phellandrene (30.6%), respectively. These compounds were followed by p-cymene (8.2%), bicyclogermacrene (6.1%) and spathulenol (9.3%). On the other hand, E. torquata oil yield was relatively lower (1.6%), with major compounds being α-pinene (18.6%), 1,8-cineole (18.8%), β-eudesmol (10.3%) and torquatone (29.2%).KEYWORDS: Eucalyptusessential oilE. camaldulensisE. torquataCyprus Disclosure statementThe authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.'),(1928,'10.1080/10412905.2022.2147675','Composition and antimicrobial activity of <i>Pastinaca sativa</i> subsp. <i>sativa</i>, <i>P. sativa</i> subsp. <i>urens</i> and <i>P. hirsuta</i> essential oils','Journal of Essential Oil Research',2022,'https://doi.org/10.1080/10412905.2022.2147675',4,'https://openalex.org/W4310248876','Composition and antimicrobial activity of root, leaf, stem, flower and fruit essential oils from cultivated Pastinaca sativa subsp. sativa, and its two wild-growing relatives P. sativa subsp. urens and P. hirsuta (Apiaceae) were investigated. Twenty-nine hydrodistilled essential oils of plants from different localities and/or years were analysed by GC-FID and GC/MS. Dominant in root oils was myristicin (P. sativa) or apiole (P. hirsuta), in leaf and stem oils myristicin (cultivated plants) or γ-palmitolactone (wild-growing plants) and in flower and fruit oils aliphatic esters. Multivariate statistics (PCA, nMDS, UPGMA clustering) generally revealed separation of oils of investigated Pastinaca taxa and demonstrated their chemosystematic significance. One oil per each organ of all three plants (fifteen in total) was tested using microdilution method for activity against Candida tropicalis, C. parapsilosis, C. krusei, C. glabrata, C. albicans, Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Escherichia coli, Salmonella Typhimurium and Enterobacter cloacae; MIC = 0.25â8 mg/mL, MBC(MFC) = 0.5â16 mg/mL.'),(1929,'10.1080/10412905.2022.2160843','Drying kinetics of cinnamon (<i>Cinnamomum zeylanicum</i> J. Presl) leaves: effects on individual volatile compounds and external color','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2022.2160843',1,'https://openalex.org/W4313592124','The post-harvest stage of crops aims to minimize losses occuring during storage and commercialization. Drying process are some of the most used methods to minimize those losses. This work aimed at studying the drying kinetics of cinnamon (Cinnamomum zeylanicum), subject to two different drying conditions, one of which in an experimental fixed-bed dryer relying on an ambient air and speed of 0.5 m sâ1, and the other with a forced air circulation oven at different temperatures (313.5, 323.15, 333.15 and 343.15 °K). The time required to reach the moisture equilibrium contents was 1.42, 3.0, 6.41, 14.0 and 21 h for drying temperatures of 343.15, 333.15, 323.15, 313.5 and 307.95 ºK, respectively. The Arrhenius equation described the diffusivityâs dependence on temperature, defining the activation energy of 64.77 kJ molâ1. The essential oils of the samples were analyzed through gas chromatography, which identified 23 individual compounds being eugenol the most abundant.'),(1930,'10.1080/10412905.2023.2167876','Chemical composition and anti-<i>Helicobacter pylori</i> activity of essential oil from fresh fruits of <i>Litsea cubeba</i> (Lour.) Pers','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2167876',7,'https://openalex.org/W4317725568','Main chemical compositions of essential oil (EO) from Litsea cubeba fruit collected in Kon Tum Province of Vietnam were geranial (32.0%), neral (24.3%), citronellal (14.2%), and limonene (10.1%). Twenty-four compounds of the EO were identified and compared with those from EOs previously reported in India, China, and Malaysia. Minimal inhibitory and bactericidal concentrations (MIC and MBC) indicated that the EO induced high levels of growth inhibition and moderate bactericidal activity against seven test Helicobacter pylori strains, including six strains resistant to one to four antibiotics, azithromycin, erythromycin, levofloxacin, and metronidazole. The bacterial biofilm formation was significantly suppressed by the EO at 1/2 and 3/4ÃMIC. The EO also exerts inhibitory activity against H. pylori-urease and convert a spiral form of H. pylori into a coccoid form. Fruit EO inhibits bacterial growth via both contact and fumigant action.'),(1931,'10.1080/10412905.2023.2167877','Biological activities and chemical composition of essential oil of <i>Achillea maritima</i> (L.) Ehrend. &amp; Y.P.Guo','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2167877',5,'https://openalex.org/W4317717478','This study aimed to describe the chemical composition of the essential oil (EO) of stems, leaves and flowers of A. maritima collected from Turkey, and verify its antimicrobial and antioxidant properties. The EO was analyzed by GC-FID and GC-MS. Fifty-nine compounds representing to 98.1% of the EO were identified. The antimicrobial activities were determined against seven bacteria and two yeast species by using disc diffusion and MIC techniques. According to the results, it was observed that there was no effect of the EO against Gram-positive bacteria. The EO showed a low effect (8â9 mm) against Gram-negative bacteria, but the EO had a high effect (20â22 mm) against the tested fungi. In addition, according to the MIC test results, the EO presented effects against C. krusei, C. parapsilosis at a concentration of 50 µl/ml. The antioxidant activity of the EO was determined as IC50 = 31.9 µl/mL.'),(1932,'10.1080/10412905.2023.2167881','Chemical components, antimicrobial and antioxidant activities of essential oil from <i>Artemisia kanashiroi</i> in Northwest China','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2167881',2,'https://openalex.org/W4317725620','Artemisia kanashiroi, is an important aromatic medicinal plant that is endemic to China. In the study, the chemical components of essential oil (EO) of A. kanashiroi obtained from different regions in China were analyzed. The results indicated that oxygenated monoterpenes are the predominant components of all EOs, and the major components were 1,8-cineole, camphor, terpine-4-ol, α-terpineol and spathulenol. The chemical composition of EOs exhibited ecological diversity driven by geographical factors. Furthermore, we evaluated the in vitro biological activities of the EOs, including their antioxidant and antibacterial activities. All of the EOs exhibited moderate to potent, broad-spectrum antibacterial and antifungal activities targeting both Gram-positive and Gram-negative bacteria. However, none of the EOs showed significant activity against the tested fungal strains. The antioxidant activity of the EOs was evaluated based on their scavenging activity against 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radicals, and all of the EOs showed significant concentration-dependent DPPH free radical scavenging activity.'),(1933,'10.1080/10412905.2023.2170483','Chemical composition, antioxidant/antibacterial activities and ADMET study of the essential oil isolated from the aerial parts of Ziziphora hispanica grown in Morocco','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2170483',6,'https://openalex.org/W4318340568','The present study aimed to characterize the chemical composition and evaluate the antioxidant and antibacterial activities along with the absorption, distribution, metabolism, excretion, toxicity (ADMET) study of the essential oil of Ziziphora hispanica (ZH-EO), collected from the Middle Atlas of Morocco (Boulmane). Results showed that a total of 119 volatile components, characterized by GC-FID and GC-MS analysis, which represents the 88.7% of the total of ZH-EO. ZH-EO displayed a bactericidal effect against Listeria monocytogenes, Pseudomonas aeruginosa and Enterococcus faecalis, and a bacteriostatic effect against Staphylococcus aureus. Furthermore, ZH-EO exhibited strong antioxidant activity against DPPH radical (IC50 = 1.3 mg/mL). The ADMET prediction showed good pharmacokinetic properties of the tested components. The findings obtained from this study suggest that Ziziphora hispanica essential oil could represent a source of bioactive molecules with antioxidant and antibacterial potential in the prevention against diseases related to oxidative stress and pathogenic bacteria.'),(1934,'10.1080/10412905.2023.2185310','Chemical composition, antimicrobial and antioxidant activities of essential oils isolated from black (<i>Piper nigrum</i> L.) and cubeb pepper (<i>Piper cubeba</i> L.) fruits from the Serbian market','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2185310',11,'https://openalex.org/W4323361674','Black (Piper nigrum L.) and cubeb pepper (Piper cubeba L.) fruits from the Serbian market were chosen as unprocessed materials for obtaining market-valuable essential oils. Since pepper fruits are only imported in Serbia, inadequate transportation and storage conditions may lead to their spoilage, negatively affecting their quality as feedstocks. To ensure the highest quality of essential oils, fruits were refrigerated upon purchase, mechanically disintegrated at colder conditions and subjected to hydrodistillation. Black (BPEO) and cubeb pepper essential oil (CPEO) contained 34 and 42 compounds, respectively. CPEO showed better inhibitory effect on B. cereus (ATCC strain) and C. albicans (isolate and ATCC strain). Both oils were not bactericidal against B. cereus (isolate and ATCC strains) and S. enterica (isolate). The best antioxidant properties were shown after 1 h of incubation. These results are valuable for further progress, development and production regarding the aromatic plant industry, pharmaceutical and food industry.'),(1935,'10.1080/10412905.2023.2232813','Essential oil variability of <i>Thymus persicus</i> (Ronniger ex Rech.f.) Jalas (Lamiaceae) during <i>in vitro</i> regeneration and <i>ex situ</i> domestication','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2232813',2,'https://openalex.org/W4382931768','Thymus persicus (Lamiaceae) is a range-restricted endemic medicinal and aromatic plant from northwest of Iran. Due to the medicinal importance and over-exploitation of the plant from its natural habitats, conservationand ex situ cultivation of the plant is needed. In the present study, essential oil variability of the plant during its in vitro conservation including in vitro regenerated plant (RP) and acclimated plant (AP) was assessed by GC-FID and GC-MS, and compared with those of growing wild plant (WP). In total, 44, 25 and 25 compounds representing 98.5%, 98.7% and 98.1% were identified in the oils of WP, RP and AP, respectively. The major identified components in the oils were 4,8-β-epoxy-caryophyllene (2.3â10.7%), α-terpineol (9.5â39.2%), linalool (5.7â15.7%) and thymol (2.6â32.8%). In vitro RP with the highest content of thymol had the greatest distance with WP. The AP was also significantly dominated with a large difference in α-terpineol.'),(1936,'10.1080/10412905.2023.2234374','Aroma profile of the essential oil from different parts of <i>Pimpinella tragium</i> and subspecies population','Journal of Essential Oil Research',2023,'http://dx.doi.org/10.1080/10412905.2023.2234374',0,'https://openalex.org/W4384934611','In this research, aroma profile variation among five population from different parts of Pimpinella tragium and its subspecies were evaluated. According to obtained results, the main chemical component of Pimpinella tragium Vill. in (Khoy) was germacrene D in seed with amount of (51.80%). In Pimpinella tragium Vill. (Ghoshchi), the predominant compound included trans-dictamnol (25.30%) in inflorescence, in addition, in the root part geijerene (26.70%) was the major constituent. Pimpinella tragium Vill. (Tabriz-Ahar), in inflorescence sabinine (36.30%), was introduced as the major compound. In the subspecies of Pimpinella tragium Vill. (Mazandaran), in inflorescence, sabinine (37.10%) was identified as the major constituent as well. In Pimpinella tragium (Alvand-Hamedan) germacrene D (43.5%) was identified in inflorescence as the major compound. In general, it seems that the high value of the essential oil composition within and among Pimpinella tragium and subspecies population could provide useful information for conservation and selection of cross-parents in breeding programs.'),(1937,'10.1080/10412905.2023.2240798','The effect of exposure to <i>Mentha suaveolens</i> Ehrh. essential oil on the electroencephalographic activity according to gender difference','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2240798',2,'https://openalex.org/W4385650740','ABSTRACTMentha suaveolens Ehrh. is an aromatic herb, traditionally used in the Mediterranean areas. Our objective was to evaluate the effect of inhalation of a commercial essential oil of M. suaveolens on human electroencephalographic (EEG) activity according to gender differences by measuring EEG power spectrum changes in healthy participants. Piperitenone oxide (55.60%) was the most abundant component in the essential oil. Our findings indicated that the inhalation of M. suaveolens essential oil produced different EEG power spectrum changes as well as affected different brain regions between genders. It could be concluded that the inhalation of M. suaveolens essential oil significantly changed the EEG wave activity according to gender and these changes may cause some alterations in the psychophysiological functions of humans. Hence, M. suaveolens essential oil may be utilized in aromatherapy for improving the psychophysiological functions of humans.KEYWORDS: electroencephalographyessential oilgenderMentha suaveolensinhalation AcknowledgmentsThe authors thank Tonia Strano for her skillful technical assistance for GC-MS analysis and Flora Srl for supplying the essential oil subject of this study.Disclosure statementNo potential conflict of interest was reported by the author(s).'),(1938,'10.1080/10412905.2023.2240802','Some quality and essential oil classifications of Turkish aniseed ( <i>Pimpinella anisum</i> L.)','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2240802',3,'https://openalex.org/W4385492732','ABSTRACTFor industries that use aniseed as a raw material, essential oil content and aroma composition are critical factors. Anise fruits were collected from 15 locations to determine these criteria. The essential oil procured by hydrodistillation was analysed by gas chromatography (GC) and gas chromatographyâmass spectrometry (GC â MS). The locations were divided into five classes according to the cluster analysis of essential oil components. The most important components that made up the classes were estragole (2.33%), transâanethole (93.90%), cis-anethole (0.21%), carvone (0.097%), p-anisaldehyde (0.651%), longifolene (1.35%), carvacrol (0.06%) and α-himachalane (0.12%). The rate of essential oil varied between 0.33-3.01% in the locations. Transâanethole is the main component of the essential oil, while their rates changed according to the populations (90.8â96.6%). Location has a significant (p â¤ 0.05) effect on the essential oil, fruit width, fruit length and a thousand fruit weight; furthermore, it is positively related.KEYWORDS: AniseedPimpinella anisumlocationessential oiltrans-anethole AcknowledgmentsWe are grateful to Ege University Planning and Monitoring Coordination of Organizational Development and Directorate of Library and Documentation for their support in editing and proofreading service of this study.Disclosure statementThe authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.Authorsâ contributionsAyÅe Betül Avcı: Conceptualization, Resource, Investigation, Supervision, Merve Göre: Formal analysis, Writing â Original Draft, Writing â Review & Editing; BintuÄ Ãztürk: Methodology.Additional informationFundingThis research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.'),(1939,'10.1080/10412905.2023.2243952','Chemical constituents, antioxidant and antibacterial activities of essential oils of <i>Ochna afzelii</i> (R. Br. ex Oliv.)','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2243952',1,'https://openalex.org/W4385723696','Essential oils (EOs) from Ochna afzelii leaves, stems and roots were extracted and characterised by hydrodistillation and Gas Chromatogragphy-Mass Spectrometry (GC/MS) techniques, respectively. Antioxidant activity was evaluated by 2,2-diphenyl-1-picrylhydrazyl (DPPH*) method while antibacterial activity was determined using agar well diffusion and broth microdilution methods. Leaf, stem, and root oils afforded thirteen, ten and seven compounds, respectively, which were characterized by a high percentage of oxygenated sesquiterpenes and sesquiterpene hydrocarbons. The major compound in O. afzelii leaf and root EOs was &amp;amp; beta;-Atlantol, while the O. afzelii stem EO had (E)-&amp;amp; beta;-ionone as its major compound. The leaf oil displayed highest antioxidant activity (IC50 = 238.14 &amp;amp; mu;L/mL). All the EOs showed antibacterial activities against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi, and Streptococcus pneumoniae, with the zones of inhibition and MIC values ranging from 12.0-18.0 mm and 2.5-10 &amp;amp; mu;L/mL, respectively. O. afzelii has a mild antioxidant effect, but can be a potential source of natural antibacterial agents.'),(1940,'10.1080/10412905.2023.2247392','Anatomical investigation, essential oil composition and antimicrobial activity of <i>Salvia aytachii</i> species from Turkey','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2247392',1,'https://openalex.org/W4386051615','ABSTRACTSalvia aytachii Vural & Adıgüzel species belong to the Lamiaceae family. It is an endemic plant and is locally known as âAy Åalbasıâ. Salvia species are generally known as adaçayı in Anatolia. It has a wide variety of traditional uses concerning the digestive system. In this study, cross-sections were taken from the leaves and stem to determine the anatomical features of S. aytachii. The characteristic elements were determined with the help of a microscope. Chemical components of the essential oil were determined by Gas ChromatographyâFlame Ionization Detector (GC-FID) and Gas Chromatography-Mass Spectrometry (GC-MS) systems. A total of 79 compounds corresponding to 91.1% of S. aytachii essential oil were determined. Major compounds were identified as camphor (20.3%), 1,8-cineole (20.0%), camphene (6.0%), myrcene (5.6%), valeranone (5.5%,) borneol (5.0%) and α-pinene (4.3%). To evaluate in vitro antimicrobial activity of the essential oil, broth microdilution method was used against Staphylococcus aureus ATCC 6538, Escherichia coli NRRL B-3008, Bacillus cereus NRRL B-3711, Bacillus subtilis NRRL B-4378 and Candida albicans ATCC 90,028. The results were found to be significant in terms of antimicrobial efficacy.KEYWORDS: Salvia aytachiianatomyessential oilGC/MSantimicrobial activity Disclosure statementNo potential conflict of interest was reported by the author(s).'),(1941,'10.1080/10412905.2023.2252416','<i>In-vitro</i> antimicrobial activity of essential oils of Tasmania','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2252416',2,'https://openalex.org/W4386216201','ABSTRACTThirteen commercial Tasmanian essential oils were evaluated for their antimicrobial activity against 14 human pathogens and cosmetic contaminants including Enterococcus hirae, Kocuria rhizophila, Staphylococcus epidermidis, Propionibacterium acnes, Staphylococcus aureus, Escherichia coli, Klebsiella aerogenes, Klebsiella pneumoniae, Pluralibacter gergoviae, Pseudomonas fluorescens, Burkholderia cepacia, Pseudomonas putida, Aspergillus brasiliensis, and Aspergillus fumigatus. The antimicrobial activities of various essential oils were evaluated using the AlamarBlue Cell Viability Assay, covering a testing concentration range from 3.125 to 800 µg/mL. Essential oils were deemed active if their minimum inhibitory concentration (MIC) value was less than or equal to 800 µg/mL. The essential oils of Rosemary (Rosmarinus officinalis ct. α-pinene), Parsley Herb (Petroselinum crispum), and Bitter Fennels (Foeniculum vulgare) demonstrated significant growth inhibitory effects on one microorganism (P. fluorescens) within an MIC value of â¤ 800 µg/mL. Big Badja Gum (Eucalyptus badjensis), Blue Gum (Eucalyptus globulus), Peppermint (Mentha piperita), and Lavender (Lavandula angustifolia) essential oils inhibited the growth of two different microorganisms. Southern Rosalina (Melaleuca ericifolia), Parsley Seed (Petroselinum crispum), Smoky Tea Tree (Leptospermum glaucescens), and Kunzea (Kunzea ambigua) essential oils exhibited an MIC value of less than or equal to 800 µg/mL against 4, 5, 6, and 8 microorganisms respectively. Notably, Coastal Tea Tree (Leptospermum laevigatum) essential oil displayed the most profound antimicrobial activity, inhibiting 11 out of 15 microbial strains within an MIC range of 50â800 µg/mL. The results of the gas chromatography analysis showed that the coastal tea tree essential oil was composed primarily of monoterpenes, with smaller amounts of sesquiterpenes and their oxygenated derivatives. 35 Compounds were identified, representing 95.50% of the compounds in the coastal tea tree essential oil. The main constituents of this essential oil were α-pinene (34.83%), followed by α- and β-eudesmols (10.21% total), and limonene (9.56%).KEYWORDS: TasmaniaAustraliaessential oilsantimicrobial activityLeptospermum spLeptospermum laevigatum AcknowledgmentsI would like to thank Dr Lucyna Balcerzak for the aid in the preliminary antimicrobial evaluations, valuable discussion regarding the antimicrobial activity of essential oils, and for reviewing the manuscript. I would like to thank Dr Jacek Åyczko for providing access to the Shimadzu GC-MS instrumentation. Lastly, I would like to thank Clare McEldowney for the fruitful discussions regarding Tasmanian essential oils.Disclosure statementNo potential conflict of interest was reported by the author(s).Data availability statementThe data that support the findings of this study are available from the corresponding author upon reasonable request.Additional informationFundingThis work was supported by the statutory funds of the Faculty of Chemistry, WrocÅaw University of Science and Technology.'),(1942,'10.1080/10412905.2023.2266430','The essential oil from leaves of <i>Mauria heterophylla</i> Kunth (Anacardiaceae): chemical and enantioselective analyses','Journal of Essential Oil Research',2023,'http://dx.doi.org/10.1080/10412905.2023.2266430',5,'https://openalex.org/W4387435851','ABSTRACTThe first chemical and enantioselective analyses of the essential oil from the leaves of Mauria heterophylla Kunth were carried out. The dry plant materialproduced an essential oil with a 0.09 ± 0.05% yield by weight. The volatile fraction was submitted to GC-MS (qualitative) and GC-FID (quantitative) analyses, on two different stationary phases. A total of forty-four constituents were detected and quantified with at least one column, corresponding to about 85.5% of the whole oil mass. Limonene (15.2%), (E)-β-caryophyllene (11.1%), α-phellandrene (10.9%), germacrene D (6.6%), α-pinene (6.4%), myrcene (3.9%), β-phellandrene (2.8%), bicyclogermacrene (2.8%), (E)-β-farnesene (2.2%) and δ-cadinene (1.2%) were major components. Furthermore, the study was complemented with the enantioselective analysis of eleven common chiral terpenes, carried out on two β-cyclodextrin-based chiral selectors. Among the chiral metabolites, (1R,4S)-(+)-camphene, (1R,5R)-(+)-β-pinene, (S)-(+)-α-phellandrene and (S)-(+)-β-phellandrene were enantiomerically pure, whereas α-pinene, sabinene, limonene, linalool, terpinen-4-ol, α-terpineol and germacrene D were present as scalemic mixtures.KEYWORDS: Mauria heterophyllagas chromatographymass spectrometryenantiomersβ-cyclodextrinEcuador Disclosure statementNo potential conflict of interest was reported by the author(s).'),(1943,'10.1080/10412905.2023.2270547','Evaluation of antimicrobial and antioxidant activity of <i>Carum copticum</i> L. essential oil encapsulated in electrospun cellulose acetate nanofibers','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2270547',5,'https://openalex.org/W4387705236','ABSTRACTThe objective of this research was to nanoencapsulate ajwain (Carum copticum L.) essential oil (EO) in cellulose acetate (CA) using the electrospinning technique and evaluate its antioxidant and antimicrobial activity. The main components of ajwain EO were thymol, p-cymene, and γ- terpinene. A zeta potential of â40.11, â37.85, â35.50, and â31.74 mV was found for nanofibers of pure CA, CA/EO 1%, 2.5%, and 5%, respectively. According to SEM images, CA electrospun nanofiber loaded with different concentrations of ajwain EO had nano-scale size and uniform morphology. The antibacterial activity enhanced with higher concentrations of EO, and it was higher for nanoencapsulated EO at the same concentration. The fibers loaded with EO were effective against the microbial strains according to the following decreasing order: E. coli > S. enteritidis > S. dysenteriae > L. monocytogenes > S. aureus. Results of the antioxidant assays showed that the ABTS and DPPH scavenging capacity and reduction potential of Fe3+ of free and nanoencapsulated EO were as follows: CA/EO 5% = CA/EO 2.5% > EO 5% > CA/EO 1% > EO 2.5% > EO 1%. Antioxidant and antibacterial activities of all EO-loaded CA nanofibers were higher than free EO.KEYWORDS: Ajwaincellulose acetateelectrospinningessential oilnanoencapsulation Disclosure statementThe authors declare that they do not have any conflict of interest.Additional informationFundingThis work was supported by a research grant from the Amol University of Special Modern Technologies, Amol, Iran.'),(1944,'10.1080/10412905.2023.2280900','Authentication of <i>Lavandula angustifolia</i> Mill. (Lamiaceae) essential oil using physical property, gas chromatography, enantiomeric selectivity, and stable isotope analyses','Journal of Essential Oil Research',2023,'https://doi.org/10.1080/10412905.2023.2280900',8,'https://openalex.org/W4388791057','Authentic Lavandula angustifolia (lavender) essential oil samples (n = 41) were procured from six producing countries. Essential oils were analyzed to determine physical properties and to determine profiles and related data by GC/MS, GC/FID, enantioselective GC, and GC/IRMS. The current study identified 43 volatile compounds that were detected in all authentic lavender samples (n = 41), and which can be considered authentic markers. Enantiomeric ranges for 15 volatile compounds and stable isotope ranges for four prominent compounds were determined in authentic lavender. Authentic samples and associated data were used to assess the quality of commercially available lavender essential oil samples (n = 12). 75% of the commercial samples studied were adulterated,and 17 volatile compounds were detected in these samples which can be considered markers for adulteration. This study establishes the utility and importance of using a multifaceted analytical approach to differentiate quality and determine authenticity of lavender essential oil.'),(1945,'10.1080/10412905.2024.2320363','Chemical screening, antimicrobial and antioxidant activities of <i>Ruta angustifolia</i> essential oil from Morocco','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2320363',3,'https://openalex.org/W4392561462','Ruta angustifolia, a wild plant which largely grows in Morocco, is commonly used in folk medicine and is believed to possess several therapeutic properties. In the present work, we aimed to determine the chemical composition, antioxidant, and antimicrobial properties of the essential oil obtained from the aerial parts of Ruta angustifolia collected from the Rif region in Morocco. The employment of gas chromatography coupled to flame ionization detector and mass spectrometry detection led to the identification of five major components, representing 91.69 % of the total volatile fraction with a dominance of nonyl methyl ketone (accounting for % 86.97 % of the whole sample). The tested essential oil displayed moderate antioxidant activity and a strong antifungal effect against Fusarium oxysporum and Botrytis cinerea with MIC values equal to 7 µL/mL and 0.81 µL/mL respectively. However, no antibacterial effect was revealed against Gram-negative or Gram-positive bacterial strains.'),(1946,'10.1080/10412905.2024.2321255','Investigation of chemical composition, anticholinesterase, antioxidant, antihemolytic and antibacterial activities of essential oil and ethanol extract from aerial parts of Algerian <i>Ammoides verticillata</i> (Brot.) Breistr','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2321255',4,'https://openalex.org/W4392471905','The essential oil (EO) and ethanolic extract (EE) of Algerian Ammoides verticillata (Brot.) Breistr. were investigated for chemical composition and biological activities. GC and GC/MS analyses of the EO revealed thymol, carvacrol, p-cymene, limonene, and γ-terpinene as major compounds. HPLC/DAD/UV analysis of EE identified luteolin 7-O-glucoside as the most prominent component. The EO showed moderate inhibition activity against acetyl and butyrylcholinesterase (AChE and BChE) compared to galanthamine, while no activity for EE was observed. Both extracts showed higher to similar antioxidant activity to that of BHT in DPPH and ABTSâ¢+ radical scavenging activity and ferric and copper reduction power. Nevertheless, weak β-carotene bleaching inhibition activity was noted for both extracts. Additionally, the EE displayed a significant antihemolytic effect against AAPH-induced hemolysis. Moreover, EO and EE showed high and no antibacterial activities, respectively. Thus, A. verticillata might represent a useful material in pharmaceutical, nutraceutical, and cosmetic applications.'),(1947,'10.1080/10412905.2024.2322592','Chemical profiling and bioactivity of <i>Aloysia citriodora</i> essential oils from four localities in Tunisia','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2322592',4,'https://openalex.org/W4392631481','The goal of this work was to investigate the chemical composition of Aloysia citriodora essential oil and its biological activities as antioxidant, antibacterial, antifungal and anti-inflammatory potentials depending on the collection region. The highest essential oil yields were in Gabes and Kairouan at the Arid bioclimatic zone. Sixty volatile compounds were identified by GC-FID-MS. The major compounds were limonene and spathulenol in Gabes at the Middle Arid. However, (E)-citral (known as geranial) was the major compound of Belli and Kairouan belonging to the Upper Semi-Arid and Upper Arid areas, respectively. The essential oil extracted from the inferior sub-humid bioclimatic zone (Boussalem) had spathulenol and caryophyllene oxide as predominant components. Inversely to DPPH and ABTS, the antioxidant activities using reducing power assay of A. citriodora essential oils significantly increased from the inferior sub-humid (Boussalem) to the Upper Arid (Kairouan) bioclimatic areas. Independently of region, A. citriodora essential oil exhibited an interesting antibacterial, antifungal and anti-inflammatory potential.'),(1948,'10.1080/10412905.2024.2322593','Chemical Compositions, and Antimicrobial and Mosquito Larvicidal Activities of Essential Oils from Four <i>Syzygium</i> Species <i>Syzygium formosum</i> (Wall.) Masam., <i>S. syzygioides</i> (Miq.) Merr. &amp; L.M. Perry, <i>S. megacarpum</i> (Craib) Rathakr. &amp; N.C. Nair, and <i>S. chantaranothaianum</i> W.K. Soh &amp; J. Parn','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2322593',7,'https://openalex.org/W4392631513','Chemical compositions in the leaf essential oils of four Syzygium species were first identified by the GC-FID/MS analysis. Monoterpene hydrocarbons (39.6-51.1%), and sesquiterpene hydrocarbons (27.0-37.8%) were the main chemical classes in S. formosum and S. syzygioides leaf oils, whereas sesquiterpene hydrocarbons (83.0-83.8%) were predominant in S. Megacarpum and S. chantaranothaianum leaf essential oils. Bicyclogermacrene (9.1-37.0%) was the principal compounds in these essential oils. All the tested essential oils with the MIC values of 16-128 µg/mL were comparable to the positive control streptomycin against Gram-positive bacteria Staphylococcus aureus and Bacillus cereus, and Gram-negative bacterium Pseudomonas aeruginosa. The leaf essential oils of S. formosum, S. syzygioides, and S. chantaranothaianum with the MIC values of 16-128 µg/mL were comparable to the positive control cycloheximide against the yeast Candida albicans. Four samples also exhibited good larvicidal activity against the mosquito Aedes aegypti with the 24-h and 28-h LC50 values of 25-40 µg/mL'),(1949,'10.1080/10412905.2024.2330915','Variation in seed yield and essential oil composition of coriander ( <i>Coriandrum sativum</i> L.)','Journal of Essential Oil Research',2024,'http://dx.doi.org/10.1080/10412905.2024.2330915',3,'https://openalex.org/W4393159878','Variations in seed yield and essential oil composition of 48 coriander (Coriandrum sativum L.) germplasms collected from various geographical locations in India were evaluated. The variation in seed yield plantâ1 (2.52â10.97 g plantâ1), essential oil content (0.08â0.56%) and linalool content (49.04â82.14%). Linalool, γ-terpinene, β-pinene, p-cymene, β-myrcene, limonene, geraniol, caryophyllene, geranyl acetate, α-terpineol, citronellol and caryophyllene were detected in one or other germplasm lines. Cluster analysis was done using Ward\'s method based on the value of all the traits, resulting in 6 distinct groups of germplasms. Among six clusters, the maximum number of accessions was grouped into cluster II (16). The seed yield plantâ1 is positively correlated with the number of umbels plantâ1, number of umbellets plantâ1, number of seeds plantâ1, number of primary and secondary branches. The selection of these traits may result in the identification of germplasm with high seed yield. The genetic diversity revealed in this study could be useful for further crop improvement programs in coriander.'),(1950,'10.1080/10412905.2024.2332379','Comparative study on chemical characteristics of essential oils and genetic characteristics of true Cinnamon ( <i>Cinnamomum zeylanicum</i> Blume) and three wild Cinnamon species of Sri Lanka','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2332379',9,'https://openalex.org/W4393233709','The present study reports for the first time a comprehensive gas chromatography coupled to flame ionisation detector and mass spectrometry detection of the essential oils from leaf, stem-bark and root bark of three wild Cinnamomum species collected from Sinharaja and Kanneliya Forests in Sri Lanka together with cultivated cinnamon (Cinnamomum zeylanicum). DNA barcoding has been carried out to identify and distinguish wild cinnamon species from commercial cinnamon species. Predominant compounds in stem bark oil were trans-Cinnamaldehyde [C. zeylanicum (68.3%)], β-linalool [Cinnamomum capparu-coronde (44.5%], β-phellandrene [Cinnamomum dubium (24.7%)] or menthol, 1\'-(butyn-3-one-1-yl) [Cinnamomum sinharajaense (17.7%)]. The predominant constituents in leaf oil were eugenol [C. zeylanicum (83.0%) and C.capparu-coronde (71.6%)], β-phellandrene [C. dubium (39.9%)] or palmitic acid [C. sinharajaense. (79.8%)]. In oil extracted from root bark, the principal constituents were either camphor [C. zeylanicum (51.1%)], methyl eugenol [C. sinharajaense (82.2%) and C. dubium (84.2%)] or safrole [C. capparu-coronde (58.6%)].'),(1951,'10.1080/10412905.2024.2332381','Effect of industrial steam distillation conditions on volatiles and antioxidant capacity of <i>Cananga odorata</i> essential oils','Journal of Essential Oil Research',2024,'http://dx.doi.org/10.1080/10412905.2024.2332381',3,'https://openalex.org/W4393160102','The ylang-ylang (Cananga odorata) essential oil is valued for its medicinal and cosmetic benefits. This study compared the volatile compounds and antioxidant capacity of six essential oils from C. odorata flowers obtained industrially by steam distillation. The volatiles were identified by gas chromatography-mass spectrometry (GC/MS). The ferric reducing antioxidant power (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, and total phenolic content (TPC) were measured by ultraviolet-visible (UV-Vis) spectrophotometry. The main components included benzyl acetate (21.78â27.82%), benzyl benzoate (12.30â18.07%), linalool (9.45â14.39%), and germacrene D (9.17â14.46%). The highest antioxidant values were shown by the sample S6 (206.50 ± 7.45 mmol TE/L, 52.03 ± 0.88 mg GAE/g), followed by S5. The multivariate analysis separated S6 and S5 from the remaining essential oils, suggesting that extraction was more influenced by the steam flow rate. Notably, the antioxidant capacity of S6 revealed a positive correlation between volatiles and TPC values. These findings denote the importance of improving empirical industrial procedures.'),(1952,'10.1080/10412905.2024.2332385','Forgotten perfumery plants: hawthorn volatile extract study','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2332385',2,'https://openalex.org/W4393072369','Since antiquity, lots of plants used in perfumery have been forgotten for different reasons. They could be of huge interest for scientific investigations, but also for developing natural perfumery ingredients. Hawthorn (Crataegus monogyna Jacq.) was mainly used in scented oils, \'antique\' oils and ointments during the nineteenth century in perfumery; before being replaced with synthetic materials. This study presents new insights into the phytochemical and olfactory profile of hawthorn, to investigate its interest in perfumery and cosmetics. Obtained by hydrodistillation of frozen flowering aerial parts, the Provencal Crataegus monogyna volatile extract showed an aniseed, green fragrance. A total of 105 components were identified using GC/MS and GC/FID techniques, accounting for 96.4% of the total GC/FID chromatogram. The volatile profile is mainly composed of hydrocarbons, oxygenated monoterpenes and aldehydes, among which linalool (20.3 ± 0.2%) appeared to be the most abundant. A strong anti-elastase (anti-ageing) activity was also highlighted.'),(1953,'10.1080/10412905.2024.2332940','Comparison of antimicrobial activities of oregano, lavender, sage, anise and clove extracts obtained by supercritical fluid carbon dioxide extraction and essential oils obtained by hydrodistillation','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2332940',4,'https://openalex.org/W4393372326','The aim of the study was to compare the extraction yields, chemical compositions and antimicrobial activities of essential oils obtained by hydrodistillation (HD) and volatile extracts obtained by supercritical fluid extraction extraction (SFE) from oregano (Origanum onites), lavender (Lavandula angustifolia), sage (Salvia officinalis), anise (Pimpinella anisum) and clove (Syzygium aromaticum). Essential oil compounds (EOCs) of the obtained materials from both techniques (HD and SFE) were determined by GC-MS/FID. Agar well diffusion method was used for the determination of antimicrobial activities on five different foodborne microorganisms (Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli Enterococcus faecalis and Klebsiella pneumoniae). According to the results; extraction yields of SFE were found to be higher than HD for all tested aromatic plants. Active ingredient ratios (carvacrol, camphor, anethole, eugenole and linalol) varied depending on the extraction methods. SFE extracts were higher antimicrobial activity than HD essential oils, except clove extract on E. faecalis.'),(1954,'10.1080/10412905.2024.2342867','Chemical analyses and antioxidant activity of the essential oils from baccharis dracunculifolia DC. In Southern Brazil','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2342867',3,'https://openalex.org/W4395465866','Baccharis dracunculifolia DC. is a Brazilian native plant species that produce essential oil with several biological activities and cosmetic applications. This study aimed to evaluate the effect of seasonality on the yield, chemical composition and antioxidant activity of B. dracunculifolia essential oils during four seasons in Southern Brazil. The extraction of the volatile compounds was carried out by hydrodistillation and the analyses of chemical composition of the species were performed by GC-FID and GC-MS, while antioxidant activity was evaluated by the DPPH method. The samples were separated into two main groups: I) winter and spring: high levels β-pinene (15.58â16.15%) and II) summer and autumn: high levels of (E)-nerolidol (17.81â21.68%). These results suggest that B. dracunculifolia essential oil presents higher levels of (E)-nerolidol during the summer and autumn and β-pinene during winter and spring. The highest antioxidant activity (88.89%) was observed during the summer with a positive correlation with limonene (r = 0.977).'),(1955,'10.1080/10412905.2024.2350409','Comparative assessment of essential oil composition and yield in <i>Cinnamomum tamala</i> leaves upon application of different drying practices','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2350409',4,'https://openalex.org/W4396844342','Cinnamomum tamala or Indian bay leaf is a widely used spice in the Asian subcontinent. The aim of this study was to assess the contents and composition of essential oils and volatiles internal pool in C. tamala leaves obtained from different drying practices such as, sun drying, freeze drying, shade drying and simultaneous oven drying at 60°C and 40°C, when compared with market-available dry leaves. Out of five different practices tested, leaves when oven dried at 60°C performed best in terms of free-radical scavenging capacities, internal pool of volatile contents (257.25 ± 37.57 μg/g of dried leaf tissue) and yields of essential oils (0.25%). This was followed by freeze-dried leaves, which showed 0.2% essential oils yield. Among the natural drying, sun dried leaves exhibited high yield of essential oils (0.16%). Performance of shade dried leaves was shown to be lowest i.e. 0.11% essential oils yield but was comparable with the yield of market-available leaves.'),(1956,'10.1080/10412905.2024.2353631','Insecticidal activity of <i>Baccharis</i> essential oils against <i>Duponchelia fovealis,</i> toxicity to strawberry leaves, and <i>in vitro</i> biocompatibility with entomopathogenic fungi','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2353631',2,'https://openalex.org/W4396946312','Duponchelia fovealis is responsible for great losses in the strawberry production, and entomopathogenic fungi (EPF) are an alternative to control this larva. They can be used in combination with other natural compounds with insecticidal activity, such as plant extracts or essential oils (EOs). Thus, our objectives are to evaluate the effects of Baccharis dracunculifolia and Baccharis uncinella EOs on strawberry leaves and third instar larvae of D. fovealis, and to evaluate their in vitro compatibility with strains of Beauveria bassiana and Cordyceps javanica. EOs were not phytotoxic to strawberry leaves at 2% v/v. Larval mortality ranged between 48% and 83% at 1% and 2%, and B. dracunculifolia EO at 2% presented the higher mortality. EO of B. uncinella (BU) at 1% was compatible with two strains of B. bassiana and C. javanica. Therefore, the combined use of BU EO with EPF may be an alternative to control D. fovealis.'),(1957,'10.1080/10412905.2024.2353632','Seaweed extracts elicitation improves leaf and essential oil production on <i>Pelargonium graveolens</i> L. Herit','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2353632',4,'https://openalex.org/W4399084948','Little is known about the role of seaweed extracts in modulating the growth and the essential oil production in geranium [Pelargonium graveolens (L.) Herit]. Hence, this work aimed to evaluate the effects of Ascophylum nodosum (AN) and Solieria chordalis (SC) extracts on biometric, biochemical and phytochemical parameters in geranium plants. The experiment was conducted at greenhouse conditions, and seaweed extracts were applied by foliar pulverization. The obtained results revealed that seaweed extracts enhanced vegetative growth, directing it towards the production of a greater number of leaves at the expense of plant height and ramifications. Additionally, chlorophyll b, total soluble sugars and essential oil yield were increased due to seaweed extracts. The main constituents of volatile oil such as Linalool, Citronellol and iso-Menthone were not changed by seaweed extract treatments, with exception of Geraniol content which were slight reduced in SC treated plants. These results suggested that seaweed extracts may be used as an eco-friendly alternative to modulate growth and productivity of geranium.'),(1958,'10.1080/10412905.2024.2368020','Gas chromatographic, sensory profile and biological properties evaluation of Egyptian <i>Jasminum grandiflorum</i> essential oil produced industrially by steam distillation','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2368020',5,'https://openalex.org/W4400053043','The present study aimed to investigate the chemical composition and antimicrobial activity of Jasminum grandiflorum L. essential oil produced for the first time at industrial level by steam distillation. Volatile and chiral compositions were analyzed by GC-MS and GC-FID. In total 130 volatile compounds were identified, which constituted more than 98% of the oils. The results revealed significant differences in terms of volatile compounds between jasmine essential oil and the absolute. Sensorial evaluation revealed the essential oil had a youthful and dynamic character with a bright, floral scent, while the absolute had a more mature and sensual scent that was richer. Antimicrobial activity of both products against eighteen human pathogens and cosmetic contaminants was evaluated. The results showed that essential oil exhibited greater antimicrobial activity, inhibiting 8 out of 17 microbial strains within the MIC range â¤800 µg/mL, compared to 2 out of 17 in the case of the absolute.'),(1959,'10.1080/10412905.2024.2371823','Headspace analysis of volatiles from commercial seeds of <i>Trigonella foenum-graecum</i> L. obtained from four Middle Eastern countries','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2371823',3,'https://openalex.org/W4400030902','Trigonella foenum-graecum L. commonly known as fenugreek, is an important economic and medicinal plant cultivated in various regions of the world. Fenugreek produces several important active chemical constituents that determine its pharmacological properties. The aim of this research was to analyze the volatile constituents spontaneously emitted by eight samples of fenugreek seeds purchased from different Middle Eastern drugstores, including Saudi Arabia, Yemen, Egypt, and Iran. A total of 70 constituents belonging to different chemical classes, including monoterpene hydrocarbons, oxygenated monoterpenes, sesquiterpene hydrocarbons, phenylpropanoids, apocarotenes, nitrogen/sulfur derivatives, and non-terpene derivatives, were characterized in the volatile emissions of the eight samples, some components with significant olfactory properties were detected such as γ-nonalactone, cumin aldehyde, (E)-cinnamaldehyde, p-anisaldehyde, and eugenol. PCA showed two macro-clusters; the first comprised two sub-groups, while the second included only Yemeni samples. The findings of this study demonstrate that the significant variation for volatile profiles in fenugreek samples which are prone to variations in the geographical origin of these samples.'),(1960,'10.1080/10412905.2024.2371825','<i>In vitro</i> and <i>in silico</i> analyses of <i>Lippia alba</i> (Verbenaceae) essential oil as an inhibitor of dengue virus and platelet activation','Journal of Essential Oil Research',2024,'http://dx.doi.org/10.1080/10412905.2024.2371825',0,'https://openalex.org/W4400780198','NA'),(1961,'10.1080/10412905.2024.2371827','Evaluation of the essential oil and tea produced from <i>Baccharis myriocephala</i> leaves','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2371827',1,'https://openalex.org/W4400332748','Abstract: Baccharis myriocephala is a carqueja species less studied than other Baccharis species. This study evaluated the chemical composition, toxicological and antioxidant potentials of the essential oils and infusions of B. myriocephala. Essential oils (hydrodistillation) and the volatile fractions of infusions (SPE) were analyzed by chromatographic techniques. The TPC and TFC of the infusions, and the antioxidant activities of essential oils and infusions were measured by spectrophotometry; their toxicological potentials were evaluated by Artemia salina bioassay (ASB). Twenty-eight terpenic compounds were identified in the essential oils, fourteen of them for the first time. Nine compounds were identified in the volatile fraction of the infusions, and seven of them were absent in essential oils. Infusions [IC50(DPPH) = 2.21 mg mLâ1] are better antioxidants than the essential oils [IC50(DPPH) = 40.37 mg mLâ1]. The essential oils were considered highly cytotoxic (LD50 = 26.64 μg mLâ1), according to the ASB.'),(1962,'10.1080/10412905.2024.2371829','Study of essential oils and hydroalcoholic extracts obtained from <i>Clinopodium vimineum</i> (Lamiaceae), according to its different phenological stages','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2371829',1,'https://openalex.org/W4400674369','The Caribbean shrub, Clinopodium vimineum, had its essential oil (EO) and hydroalcoholic extracts analyzed across three growth stages: vegetative, flowering, and post-flowering. The chemical composition of the EOs was analyzed by GC/MS/FID and that of the extracts was studied by UHPLC/ESI-Q-Orbitrap-MS. Twenty six compounds (>0.1%) were detected in the EOs of C. vimineum. p-Menth-3-en-8-ol (35â40%) and pulegone (27â30%) were the major components. Among the hydroalcoholic extracts, hydroxycinnamic acids (18â46 mg/g) and glycosylated flavones (17â19 mg/g) were found. The amounts of rosmarinic acid (20â40 mg/g) in the extracts isolated from the hydrodistillation residual biomass were twice as high as those in the extracts from the fresh plant material. The antioxidant activity of the EOs and extracts was evaluated by the ABTS+â¢ and ORAC assays. No significant differences (p > 0.05) were found in the chemical composition or antioxidant activity of EOs and hydroalcoholic extracts, obtained from plants collected at different phenological stages.'),(1963,'10.1080/10412905.2024.2371830','Effect of light emitting diodes (LEDs) irradiation on the functional quality and shelf life of basil microgreens','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2371830',7,'https://openalex.org/W4400674527','Light-emitting diodes (LEDs) are the promising technology with low heat production and feasible spectra optimization, which improve plants\' function. In current study, basil microgreens as novel-leafy vegetables grown under LEDs (blue, red, 30%blue +70%red, and white) and sunlight to investigate phytochemical properties by comparing to sunlight-treated mature basil. Results showed that narrow wavelength including blue, red and blue/red LEDs had significant effect on increasing total phenol content (TPC) and antiradical activity (AA) of microgreens. Blue LED-treated microgreens exhibited significant increase in Potassium and the best visual appearance in comparison with mature and other microgreens. In the case of essential oils, methyl chavicol was the major compound in all samples with the main effect of broad light spectra; red LED- and blue LED-treated microgreens represented the maximum and minimum of methyl eugenol and β-caryophyllene, respectively, which could be related to the significant effect of red light on essential oil biosynthesis. No significant difference was observed in the market-acceptability of mature basil and microgreens which demonstrated that LEDs had no negative impact on organoleptic properties. Throughout the storage, darkness-stored microgreens showed the best result with the least weight loss and decrease in TPC; however, brightness-yellowness variation observed due to the plants\' aging.'),(1964,'10.1080/10412905.2024.2389402','Isolation and characterization of <i>Thymus serpyllum</i> L. essential oil and mass fragmentation analysis of major constituents','Journal of Essential Oil Research',2024,'http://dx.doi.org/10.1080/10412905.2024.2389402',3,'https://openalex.org/W4401689080','The essential oils were isolated from Thymus serpyllum L. leaves, stem, flowers and whole plant using hydrodistillation technique and % yield was determined. The chemical constituents were studied using Gas Chromatography-Mass Spectrometry and Gas Chromatography-Flame Ionisation Detection. The analysis revealed the presence of 38 compounds in the essential oils obtained from different plant parts. Identification of compounds was achieved by detailed analysis of mass spectrum and retention indices. The major constituents of essential oil from the whole plant were thymol (35.25%), p-cymene (27.57%), thymol acetate (8.03%) and γ-terpinene (6.92%). In leaves they were thymol (45.59%), p-cymene (24.26%), thymol acetate (6.41%), and β-bisabolene (5.91%); whereas in flowers these were thymol (68.74%) and thymol acetate (7.40%) and in the stem, these were thymol (55.15%) and thymol acetate (8.01%). Specifically, it is the first report wherein essential oil constituents of T. serpyllum L. whole plant, leaves, flowers, and stems have been analyzed separately. Further, fundamental analysis of complex mass fragmentation patterns of terpenes and terpenoids using EI-MS has been achieved and the logical reason for the fragmentation pattern has been elaborated. Detailed elaboration of the mass fragmentation pattern may strengthen the EI-MS-based compound identification of terpenes and terpenoids from essential oils.'),(1965,'10.1080/10412905.2024.2389404','The leaf essential oil of Ecuadorian <i>Ophryosporus peruvianus</i> (J.F. Gmel.) R.M. King &amp; H. Rob: chemical composition, enantioselective analysis, and <i>in vitro</i> enzymatic inhibitory activity','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2389404',5,'https://openalex.org/W4401552230','An Ecuadorian specimen of Ophryosporus peruvianus produced an essential oil with a yield of 0.4% of the weight of the fresh plant material. A total of thirty-two compounds were detected and quantified. The chemical composition showed the predominance of monoterpene hydrocarbons, with sabinene (22.5%), β-pinene (15.1%), limonene (8.3%), β-phellandrene (29.7%), δ-elemene (2.1%), and epi-α-cadinol (2.7%) being the main components, expressed as mean values on two stationary phases of different polarity. This composition was very different from that reported in the literature for the essential oil of a Peruvian specimen, which was dominated by sesquiterpene hydrocarbons. These results indicate the existence of different chemotypes of O. peruvianus. Moreover, an enantioselective analysis of the major chiral constituents was performed, which revealed (R)-(-)-β-phellandrene, (R)-(-)-β-phellandrene and (1R,9R,E)-(-)-β-caryophylleneas enantiomerically pure compounds. On the other hand, β-thujene, β-pinene, β-pinene, sabinene, limonene, and terpinen-4-ol were scalemic mixtures. Finally, a preliminary screening of enzymatic inhibitory activity was performedin vitro, showing modest but interesting inhibition of both butyrylcholinesterase and lipase.'),(1966,'10.1080/10412905.2024.2389406','Unveiling the aromatic secrets: analysis of odor-active components in <i>Cupressus torulosa</i> needles essential oil using GC-O and aroma extract dilution analysis','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2389406',4,'https://openalex.org/W4401592600','The essential oils derived from various coniferous species, including Cupressus torulosa, have been historically valued for their aromatic properties. In the present study, essential oil from C. torulosa needles (CTEO) was analyzed using Gas Chromatography (GC), Gas Chromatography-Mass Spectrometry (GC-MS), and Gas Chromatography-Olfactometry (GC-O) with Aroma Extract Dilution Analysis (AEDA). A total of 36 compounds were identified, with δ-3-carene (0.1824 ± 0.0084 mg/g), sabinene (0.1125 ± 0.036 mg/g), and terpinen-4-ol (0.0891 ± 0.0034 mg/g) as major constituents. Of these, 24 were odor-active. The aroma profile of CTEO featured top notes of green, fresh leafy, cool, fruity, and citrus scents, middle notes of dry woody tones, and base notes of spicy and dry characteristics. Predictive models including FD factor, Odor Activity Values, and Relative Flavor Activity highlighted α-pinene, α-terpinene, linalool, bornyl acetate, β-pinene, camphor, limonene, and terpinen-4-ol as key aroma contributors. This study provides valuable insights into the aromatic profile of CTEO, with potential applications in the aroma industry.'),(1967,'10.1080/10412905.2024.2391851','Neopetasan, the main component of the essential oil from <i>Cyperus sesquiflorus</i> (Cyperaceae)','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2391851',2,'https://openalex.org/W4402089285','NA'),(1968,'10.1080/10412905.2024.2392188','Chemical composition, antimicrobial and antibiofilm activities of essential oil from Turkish endemic <i>Prangos hulusii</i> fruits','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2392188',1,'https://openalex.org/W4401791836','The chemical composition, antimicrobial, and antibiofilm activities of the essential oil from the fruits of Turkish endemic Prangos hulusii were studied. Essential oil was analyzed by GC and GC/MS. Thirty-nine compounds were identified, which represent 98.6% of the total composition of the essential oil. Monoterpene hydrocarbons and sesquiterpene hydrocarbons were the most represented classes of volatiles with 49.8% and 21.0%, respectively. The main constituents of the essential oil were (E)-methyl cinnamate (22.9%), α-phellandrene (13.8%), and (E)-β-ocimene (12.9%). (E)-methyl cinnamate was detected in Prangos spp. for the first time. Antimicrobial activities against three Gram-positive bacteria, three Gram-negative bacteria, and three yeast strains were evaluated using disk diffusion test and microdilution method. Antibiofilm experiments were done by spectrophotometric microplate method and the results of Staphylococcus aureus, Escherichia coli, and Candida albicans were visualized via scanning electron microscopy. The essential oil had an antimicrobial effect and showed an antibiofilm effect on these strains.'),(1969,'10.1080/10412905.2024.2396854','Chemical composition and antibacterial activity of essential oils extracted from fresh and dried aerial parts of <i>Rosmarinus officinalis</i> L. <i>Pistacia lentiscus</i> L. and <i>Thymus vulgaris</i> L. from Algeria','Journal of Essential Oil Research',2024,'http://dx.doi.org/10.1080/10412905.2024.2396854',2,'https://openalex.org/W4402721581','International audience'),(1970,'10.1080/10412905.2024.2397688','Phytochemical analysis and insecticidal effect of essential oils from <i>Myroxylon peruiferum</i> (Leguminosae) and <i>Eugenia gracillima</i> (Myrtaceae) for the control of <i>Aedes aegypti</i> (Diptera: Culicidae)','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2397688',1,'https://openalex.org/W4402567420','NA'),(1971,'10.1080/10412905.2024.2397689','<i>In vitro</i> antimicrobial activity of chlorhexidine in combination with essential oils of <i>Mentha x piperita</i> L. &amp; <i>Thymus serpyllum</i> L. &amp; <i>Pelargonium graveolens</i> Lâhér','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2397689',3,'https://openalex.org/W4402398170','NA'),(1972,'10.1080/10412905.2024.2401844','Chemical composition, toxicity, microencapsulation, and application of <i>Cinnamomum cassia</i> essential oil in maize flour: evaluating the persistence of aroma and color','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2401844',4,'https://openalex.org/W4402549488','NA'),(1973,'10.1080/10412905.2024.2404085','Effect of cultivation and geographical location on chemical composition and enantiomeric distribution in linalool-rich <i>Origanum dubium</i> Boiss. essential oils obtained at different growth stages','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2404085',4,'https://openalex.org/W4402678939','NA'),(1974,'10.1080/10412905.2024.2421551','Essential oils of the Lamiaceae family, their blends and their major compounds in the management of the spider mite, <i>Tetranychus urticae</i> Koch','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2421551',2,'https://openalex.org/W4404205152','NA'),(1975,'10.1080/10412905.2024.2426488','Chemical composition and antibacterial activity of the essential oils of <i>Asphodelus microcarpus Salzm. &amp; Viv.</i> growing wild at different sites in Morocco: ADME-Tox, molecular docking and molecular dynamics simulations','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2426488',7,'https://openalex.org/W4404733295','NA'),(1976,'10.1080/10412905.2024.2447712','New insights on the chemical composition of essential oils from Vietnamese <i>Piper umbellatum</i> L. investigated by combination of chromatographic and spectroscopic techniques','Journal of Essential Oil Research',2024,'https://doi.org/10.1080/10412905.2024.2447712',1,'https://openalex.org/W4405880360','NA'),(1977,'10.1080/10496475.2019.1579148','Investigation on Biomolecules in Ethanol Extract of Fruits of<i>Prosopis Juliflora</i>(Sw.) DC. Using GC-MS','Journal of Herbs Spices & Medicinal Plants',2019,'https://doi.org/10.1080/10496475.2019.1579148',11,'https://openalex.org/W2912533866','One hundred and twenty-one compounds were identified by GC-MS analysis of ethanol extract of fruits from Prosopis juliflora. The major constituents identified were terpenoids: Limonene diol, Dihydrocarvone, Limonene dioxide, trans-Carveol, Dinorsesquiterpenoid, and fatty acids and its derivatives: 2-chloroethyl linoleate, Cis-Vaccenic acid, Linoleic acid. The minor compounds identified were Monolinolein, Ricinoleic acid, Ethyl elaidate, Palmitic acid, Mome inositol, Uroterpenol, p-methylacetophenone, Glycerol, Limonene, and Cyclooctanone.'),(1978,'10.1080/10575630108041259','Headspace Constituents of the Tree Remain of<i>Cinnamomum camphora</i>','Natural product letters',2001,'https://doi.org/10.1080/10575630108041259',19,'https://openalex.org/W2050651120','The volatile ingredients isolated from a fresh tree of Cinnamomum camphora (camphor tree) and from a tree remain of C. camphora were collected by using headspace techniques and analyzed by means of gas chromatography/mass spectrometry (GC/MS). 99.77% of the constituents consisting 23 components from the fresh tree, 98.68% of the constituents consisting 24 components from the tree remain were identified. Of these ingredients, camphor was obtained as the most abundant component.'),(1979,'10.1080/10915810152902592','Final Report on the Safety Assessment of Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, and Mentha Piperita (Peppermint) Leaf Water','International Journal of Toxicology',2001,'https://doi.org/10.1080/10915810152902592',147,'https://openalex.org/W7636706','Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Leaf Extract, Mentha Piperita (Peppermint) Leaf, Mentha Piperita (Peppermint) Leaf Water are obtained from the Mentha piperita plant. The oil is currently used in cosmetic formulations as a fragrance component, but previously had been also described as a denaturant. The extract and leaves are described as biological additives, but only the extract is reported to be used. Peppermint Water is described as a flavoring agent or fragrance component, but is not currently in use. Peppermint Oil is used at a concentration of < or = 3% in rinse-off formulations and < or = 0.2% in leave-on formulations. Peppermint Oil is composed primarily of menthol and menthone. Other possible constituents include pulegone, menthofuran, and limone. Most of the safety test data concern Peppermint Oil. The oil is considered to present the \"worst case scenario\" because of its many constituents, so data on the oil were considered relevant to the entire group of ingredients. Peppermint Oil was minimally toxic in acute oral studies. Short-term and sub-chronic oral studies reported cystlike lesions in the cerebellum in rats that were given doses of Peppermint Oil containing pulegone, pulegone alone, or large amounts (>200 mg/kg/day) of menthone. Pulegone is also a recognized hepatotoxin. Repeated intradermal dosing with Peppermint Oil produced moderate and severe reactions in rabbits, although Peppermint Oil did not appear to be phototoxic. Peppermint Oil was negative in the Ames test and a mouse lymphoma mutagenesis assay but gave equivocal results in a Chinese hamster fibroblast cell chromosome aberration assay. In a carcinogenicity study of toothpaste and its components, no apparent differences were noted between mice treated with Peppermint Oil and those treated with the toothpaste base. Isolated clinical cases of irritation and/or sensitization to Peppermint Oil and/or its constituents have been reported, but Peppermint Oil (8%) was not a sensitizer when tested using a maximization protocol. It was expected that dermal absorption of Peppermint Oil would be rapid, following that of menthol, a major component, but in no case would be greater than absorption through the gastrointestinal tract. Because of the toxicity of pulegone, the safe concentration of this constituent was limited to < or = 1%. This concentration was achievable both by controlling the time of harvest and processing technique. There is evidence that menthol can enhance penetration of other agents. Formulators were cautioned that this enhanced penetration can affect the use of other ingredients whose safety assessment was based on their lack of absorption. With the limitation that the concentration of pulegone in these ingredients should not exceed 1%, it was concluded that Mentha Piperita (Peppermint) Oil, Mentha Piperita (Peppermint) Extract, Mentha Piperita (Peppermint) Leaves, Mentha Piperita (Peppermint) Water are safe as used in cosmetic formulations.'),(1980,'10.1080/10942912.2023.2286896','Contact toxicity and repellent activity of essential oils from <i>Alpinia zerumbet</i> cv. âVariegataâ against stored product insects','International Journal of Food Properties',2023,'https://doi.org/10.1080/10942912.2023.2286896',8,'https://openalex.org/W4389206836','ABSTRACTAlpinia zerumbet cv. âVariegataâ, as a special spice, has attracted social attention for its potential to replace synthetic chemicals as insecticides and repellents in food protection. In this work, the essential oils (EOs) from different organs of Alpinia zerumbet cv. âVariegataâ (stem and leaf, flower, and rhizome) were extracted by hydrodistillation and analyzed by gas chromatography-mass spectrometry (GC-MS). The contact toxicities and repellent activities of the extracted EOs, along with their common components, against three insect species (Tribolium castaneum, Lasioderma serricorne, and Liposcelis bostrychophila) were evaluated. GC-MS analysis identified 25 components, and eucalyptol and camphor were the common primary components in the three EOs. The result showed that EOs and the main components (eucalyptol and camphor) exhibited varying degrees of contact toxicity and repellent activity against three insect species. Camphor exhibited more obvious contact toxicity than eucalyptol against both insect species (L. serricorne and L. bostrychophila), but the toxic effect was opposite for T. castaneum. The gray relation analysis explained that REOA had the strongest repellency against L. serricorne, with a coefficient of 0.52. The results in this study suggest that EOs of A. zerumbet cv. âVariegataâ have the potential to be developed into botanical insecticides and repellents to control stored-product insects.'),(1981,'10.1080/14786410310001608145','Analysis of essential oil of <i>Satureja thymbra</i> by hydrodistillation, thermal desorber, and headspace GC/MS techniques and its antimicrobial activity','Natural Product Research',2004,'https://doi.org/10.1080/14786410310001608145',54,'https://openalex.org/W2105049436','The essential oil composition of Satureja thymbra was analyzed by direct thermal desorber and Headspace GC/MS analysis methods. Its constituents were determined to be mainly carvacrol (40.15%), gamma-terpinene (26.56%), p-cymene (16.39%), and thymol (13.16%). The other techniques, thermal desorber and Headspace GC/MS, were used for the plant leaves at three different temperature, which showed similar results. The thermal desorber GC/MS gave better and more sensitive results than Headspace GC/MS. The essential oil was found to be active against the bacteria Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Shigella sonnei, and Staphylococcus aureus and the yeast Candida albicans.'),(1982,'10.1080/14786410500462678','Constituents of the essential oil from aerial parts of<i>Chromolaena odorata</i>from Thailand','Natural Product Research',2006,'https://doi.org/10.1080/14786410500462678',35,'https://openalex.org/W2080028723','The chemical composition of the essential oil from the aerial parts of Chromolaena odorata, collected from Phitsanulok, Thailand was analyzed by means of GC-(FID) and GC-MS. Twenty-two constituents were identified. The major components were pregeijerene (17.6%), germacrene D (11.1%), alpha-pinene (8.4%), beta-caryophyllene (7.3%), vestitenone (6.5%), beta-pinene (5.6%), delta-cadinene (4.9%), geijerene (3.1%), bulnesol (2.9%), and trans-ocimene (2.2%).'),(1983,'10.1080/14786419.2010.487190','Essential oil composition of aerial parts of<i>Cyclospermum leptophyllum</i>(Pers.) Sprague ex Britton and P. Wilson','Natural Product Research',2011,'https://doi.org/10.1080/14786419.2010.487190',10,'https://openalex.org/W2029696698','The essential oil of Cyclospermum leptophyllum (Pers.) Sprague ex Britton and P. Wilson syn. Apium leptophyllum (Pers.) F. Muell. Ex Benth., family Apiaceae (Umbellifereae), was analysed by GC and GC-MS. The essential oil showed the presence of thymohydroquinone dimethyl ether (50.7%), thymol methyl ether (11.2%), γ-terpinene (10.4%), p-cymene (9.5%) and carvacrol methyl ether (5.9%), along with trans-ocimene, β-pinene, germacrene D, cumin aldehyde, α-humulene, β-myrcene, sabinene, limonene, β-phellandrene, caryophyllene oxide, α-pinene and α-thujene as minor constituents. To the best of our knowledge, this is the first study of the essential oil composition of C. leptophyllum collected from India.'),(1984,'10.1080/14786419.2010.531724','Volatile oils from the plant and hairy root cultures of<i>Ageratum conyzoides</i>L.','Natural Product Research',2011,'https://doi.org/10.1080/14786419.2010.531724',17,'https://openalex.org/W2125571641','Two lines of hairy root culture of Ageratum conyzoides L. induced by Agrobacterium rhizogenes ATCC 15834 were established under either complete darkness or 16 h light/8 h dark photoperiod conditions. The volatile oil yields from aerial parts and roots of the parent plant, the hairy root culture photoperiod line and the hairy root culture dark line were 0.2%, 0.08%, 0.03% and 0.02%, (w/w), respectively. The compositions of the volatiles from the hairy roots, plant roots and aerial parts were analysed by GC and GC-MS. The main components of the volatiles from the hairy root cultures were β-farnesene, precocene I and β-caryophyllene, in different amounts, depending on light conditions and also on the age of cultures. Precocene I, β-farnesene, precocene II and β-caryophyllene were the main constituents of the volatile oils from the parent plant roots, whereas precocene I, germacrene D, β-caryophyllene and precocene II were the main constituents of the aerial parts of the parent plant. Growth and time-course studies of volatile constituents of the two hairy root lines were compared. Qualitative and quantitative differences were found between the volatile oils from the roots of the parent plant and those from the hairy roots.'),(1985,'10.1080/14786419.2010.534994','Comparative study of composition and biological activities of SDE prepared essential oils from flowers and fruits of two<i>Hypericum</i>species from central Iran','Natural Product Research',2011,'https://doi.org/10.1080/14786419.2010.534994',27,'https://openalex.org/W1970504947','Essential oil (EO) compositions of flowers and fruits of Hypericum perforatum L. and Hypericum scabrum L. growing wild in Kashan, central Iran, were determined by simultaneous steam distillation-solvent extraction method and analysed using GC-MS technique. Analysis revealed 28 identified compounds for H. perforatum, with two main components being α-pinene (25.36%) and α-amorphene (12.12%). Thirty-five compounds were identified in H. scabrum L. representing 98.60% of the oil with α-pinene (70.21%) and p-mentha-1,5-dien-8-ol (2.89%) as main components. Some new compounds were found in significant quantities which were not found in other chemotypes. The antioxidant activities of the EOs evaluated for the first time in this study using β-carotene bleaching and DPPH assays seemed to be attributed directly to α-pinene contents in them. Antibacterial activities of both mentioned EOs were higher than that of their main constituent, α-pinene, against Staphylococcus aureus and Escherichia coli.'),(1986,'10.1080/14786419.2010.534998','Volatile constituents and antioxidant activity of flowers, stems and leaves of<i>Nasturtium officinale</i>R. Br.','Natural Product Research',2011,'https://doi.org/10.1080/14786419.2010.534998',55,'https://openalex.org/W2058824214','GC-MS analyses of the essential oils of leaves, stems and flower of Nasturtium officinale resulted in the identification of 9, 8 and 15 compounds, representing 97%, 100% and 94.7% of the oils, respectively. The main compounds of the oil of leaves were myristicin (57.6%), α-terpinolene (8.9%) and limonene (6.7%). Caryophyllene oxide (37.2%), p-cymene-8-ol (17.6%), α-terpinolene (15.2%) and limonene (11.8%) were the main components in stems, whereas limonene (43.6%), α-terpinolene (19.7%), p-cymene-8-ol (7.6%) and caryophyllene oxide (6.7%) were the major constituents in the oil of flowers. All the samples were subjected to a screening for their possible antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and β-carotene-linoleic acid assays. In the above tests, methanol extracts of leaves showed higher antioxidant activity than the oils and methanol extracts of stems and flowers.'),(1987,'10.1080/15569543.2018.1434795','Volatile, non-volatile composition and insecticidal activity of <i>Eupatorium adenophorum</i> Spreng against diamondback moth, <i>Plutella xylostella</i> (L.), and aphid, <i>Aphis craccivora</i> Koch','Toxin Reviews',2018,'https://doi.org/10.1080/15569543.2018.1434795',33,'https://openalex.org/W2790385912','Essential oil (EO) from aerial parts of Eupatorium adenophorum Spreng was extracted by steam distillation and characterized by Gas chromatography (GC) and gas chromatographyâmass spectrometry (GC-MS). α-epi-cadinenol (16.63%), O-cymene (13.54%), bornyl acetate (7.70%), β-phellandrene (7.46%), and Ï-2-carene (5.77%) were the major terpenoids. The EO showed promising toxicity (median lethal concentration, LC50 = 3176.54 mg Lâ1) and repellent activity (median repellent concentration, RC50 = 2070.99 mg Lâ1) to larvae of Plutella xylostella within 24 h. Among fractions, hexane fraction was more effective to P. xylostella (LC50 = 5056.74 mg Lâ1), whereas methanol fraction to Aphis craccivora (LC50 = 1175.83 mg Lâ1).'),(1988,'10.1080/22297928.2020.1862703','Morphological, Cytological, and Chemotypic Variation of Essential Oils in<i>Syzygium cumini</i>(L.) Skeels','Analytical Chemistry Letters',2020,'https://doi.org/10.1080/22297928.2020.1862703',6,'https://openalex.org/W3117143309','Syzygium cumini, is a medicinally important plant and exhibits a wide range of cytomorphological diversity. The present attempt was made to study the detailed meiotic course in five different populations from North India. The meiotic analysis depicts the presence of three cytotypes with 2n = 22, 44, and 66. These cytotypes were further subjected to the chemical analysis of the content and composition of leaf essential oil by GC-MS. All three-leaf samples (SLS-1, SLS-2, and SLS-3) collected from the same study area (Patiala, Punjab) were reported to be different in the content and composition of their essential oil components. The extraction yields of oils from leaves were 0.37 % (SLS-1), 0.42 % (SLS-2), and 0.39 % (SLS-3), respectively. The essential oil constituents identified were 38, 39, and 39 out of total 40 constituents for each oil sample representing 99.08 %, 99.52 %, and 99.39 % of the compositions, respectively. The major constituents of leaf essential oil of sample SLS-1 were: Iso-dihydrocarveol (14.61 %); (Z)-β-ocimene (12.02 %). From sample SLS-2 were (Z)-β-ocimene (19.45 %); α-pinene (14.80 %). From the sample, SLS-3 was: (Z)-β-ocimene (13.75 %); α-pinene (9.08 %), respectively. The present study identifies the best cytotype which can be preferably cultivated commercially for their use in the preparation of medicines and other formulations.'),(1989,'10.1080/22311866.2021.1886989','Chemical Characterization of <i>Schefflera actinophylla</i> (Endl.) Harms Essential Oil: Antifungal and Antimycotoxin Activities for Safe Storage of Food Grains','Journal of Biologically Active Products from Nature',2021,'https://doi.org/10.1080/22311866.2021.1886989',2,'https://openalex.org/W3133733734','Cereals are more prone to fungal attacks, which lead to enormous yield loss and reduction in seed quality, nutritional values, and germination. A large number of seed-borne fungi being produced with low molecular weight toxic secondary metabolites called mycotoxins. The present research work evaluated the antifungal and antimycotoxigenic activities of the essential oil of Schefflera actinophylla (SAEO). The GC/MS analysis confirms the presence of 15 phytochemical constituents in SAEO, among which, β-caryophyllene (49.23 %) and α-humulene (26.17 %) were recorded as major chemical components (> 25 %). The SAEO showed broad-spectrum antifungal activity against 15 different seed-borne phytopathogenic fungi with percent mycelial growth inhibition (%MI), minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) ranged between 8.8-26.5 % at 1 μL mL-1, 0.156-2.5 μL mL-1, and 2.5- >10.0 μL mL-1, respectively. The aflatoxin B1 (AFB1) and fumonisin B1 (FB1) production from toxigenic isolates of A. flavus and F. verticillioides were significantly inhibited by SAEO at 10 μL mL-1, respectively. In the viable maize model assay, the incidences of species of Alternaria, Aspergillus, Fusarium, and Penicillium were decreased in SAEO treated samples with increasing seed germination. The obtained result confirms that SAEO could be used as an alternative source for managing mold and mycotoxins contamination in food- and feedstuffs.'),(1990,'10.1093/chromsci/bmv136','Comparison of Ultrasound-Assisted Headspace Solid-Phase Microextraction and Hydrodistillation for the Identification of Major Constituents in Two Species of<i>Hypericum</i>','Journal of Chromatographic Science',2015,'https://doi.org/10.1093/chromsci/bmv136',12,'https://openalex.org/W1819168104','Ultrasound-assisted headspace solid-phase microextraction (UA-HS-SPME) and hydrodistillation (HD) methods, coupled to gas chromatography-mass spectrometry (GC-MS), were used for the extraction and analysis of volatile compounds from Hypericum perforatum and Hypericum scabrum collected from two different sites in Iran. In the UA-HS-SPME method, various experimental parameters such as the type of fiber coating, sonication time, extraction time, extraction temperature and desorption time were investigated. The highest extraction efficiency was achieved by a 100-µm polydimethylsiloxane (PDMS) fiber. Consequently, 36 compounds were identified in H. perforatum and H. scabrum samples, using the UA-HS-SPME-GC-MS method, of which 14 were the same in both species. On the other hand, 57 compounds of these species were identified by the HD-GC-MS method, of which 21 were the same. The predominant constituents identified using the UA-HS-SPME method in H. perforatum included β-caryophyllene, α-pinene, γ-cadinene, α-selinene, germacrene-D, limonene and myrcene, and in H. scabrum were α-pinene, nonane, β-pinene and limonene. The common constituents identified by the HD-GC-MS method for H. perforatum involved germacrene-D, limonene, β-caryophyllene, α-pinene, β-pinene and germacrene-B, and for H. scabrum were α-pinene, β-pinene, germacrene-D, nonane, limonene and γ-cadinene. The results about the main constituents of the examined species correspond to the findings of other researchers. Additionally, comparing UA-HS-SPME-GC-MS and HD-GC-MS methods showed that the UA-HS-SPME-GC-MS method is much faster and simpler, and it requires much less sample size and lower temperature.'),(1991,'10.1099/jmm.0.46443-0','Antifungal activity of the essential oil of Thymus pulegioides on Candida, Aspergillus and dermatophyte species','Journal of Medical Microbiology',2006,'https://doi.org/10.1099/jmm.0.46443-0',323,'https://openalex.org/W2141078073','The composition of the essential oil of Thymus pulegioides and its antifungal activity on Candida, Aspergillus and dermatophyte fungal strains were studied. Essential oil from the aerial parts of the plant was obtained by hydrodistillation and analysed by GC and GC-MS. The oil showed high contents of carvacrol and thymol. The MIC and minimal lethal concentration were used to evaluate the antifungal activity against Candida (seven clinical isolates and four ATCC type strains), Aspergillus [five clinical isolates, and two Colección Española de Cultivos Tipo (CECT) and two ATCC type strains] and five clinical dermatophyte strains. Antifungal activity was evaluated for the essential oil and for its main components. To clarify its mechanism of action on yeasts and filamentous fungi, flow-cytometric studies of cytoplasmic membrane integrity were performed, and the effect on the amount of ergosterol was investigated. Results showed that T. pulegioides essential oil exhibited a significant activity against clinically relevant fungi, mainly due to lesion formation in the cytoplasmic membrane and a considerable reduction of the ergosterol content. The present study indicates that T. pulegioides essential oil has considerable antifungal activity, deserving further investigation for clinical applications.'),(1992,'10.1127/1864-1318/2008/0127-0039','Ultrastructural localization of acid phosphatase in the green alga Ulva rigida (Ulvales, Chlorophyta)','Algological Studies',2008,'https://doi.org/10.1127/1864-1318/2008/0127-0039',0,'https://openalex.org/W2094561762','Intracellular acid phosphatase activity has been detected in the marine macroalga Ulva rigida. Cytochemical experiments conducted in vegetative cells evidenced the presence of the reaction product adjacent to or along the plasma- lemma, within cytoplasmic vesicles and associated with different vacuolar inclu- sions such as vesicles and multivesicular bodies. This observation leads to infer that acid phosphatases are part of a system through which the orthophosphate anion is obtained from phosphate esters.'),(1993,'10.1155/2012/649727','Chemical Composition and<i>In Vitro</i>Cytotoxic Activity of Essential Oil of Leaves of<i>Malus domestica</i>Growing in Western Himalaya (India)','Evidence-based Complementary and Alternative Medicine',2012,'https://doi.org/10.1155/2012/649727',48,'https://openalex.org/W2013576004','Light pale-colored volatile oil was obtained from fresh leaves of Malus domestica tree, growing in Dhauladhar range of Himalaya (Himachal Pradesh, India), with characteristic eucalyptol dominant fragrance. The oil was found to be a complex mixture of mono-, sesqui-, di-terpenes, phenolics, and aliphatic hydrocarbons. Seventeen compounds accounting for nearly 95.3% of the oil were characterized with the help of capillary GC, GC-MS, and NMR. Major compounds of the oil were characterized as eucalyptol (43.7%), phytol (11.5%), α-farnesene (9.6%), and pentacosane (7.6%). Cytotoxicity of essential oil of leaves of M. domestica was evaluated by sulforhodamine B (SRB) assays. The essential oil of leaves of M. domestica, tested against three cancer cell lines, namely, C-6 (glioma cells), A549 (human lung carcinoma), CHOK1 (Chinese hamster ovary cells), and THP-1 (human acute monocytic leukemia cell). The highest activity showed by essential oil on C-6 cell lines (98.2%) at concentration of 2000 μg/ml compared to control. It is the first paper in literature to exploit the chemical composition and cytotoxic activity of leaves essential oil of M. domestica.'),(1994,'10.1155/2013/195057','Chemical Composition of the Essential oil of <i>Chromolaena odorata</i> (L.) R. M. King &amp; H. Rob. Roots from India','Journal of Chemistry',2013,'https://doi.org/10.1155/2013/195057',23,'https://openalex.org/W2062006881','The hydrodistilled essential oil of the roots of Chromolaena odorata (L.) R. M. King &amp; H. Rob. was analysed by gas chromatography equipped with flame ionization detector (GCâFID) and gas chromatography coupled with mass spectrometry (GC/MS). A total of twentyânine compounds have been identified, accounting 97.6% of the total oil. The main constituents were himachalol (24.2%), 7âisopropylâ1,4âdimethylâ2âazulenol (17.6%), androencecalinol (14.1%), and 2âmethoxyâ6â(1âmethoxyâ2âpropenyl) naphthalene (5.6%). The essential oil consists mainly of phenyl derivatives (41.6%), followed by oxygenated sesquiterpenes ((26.6%), longâchain hydrocarbons (18.9%), sesquiterpene hydrocarbons (6.8%), oxygenated monoterpenes (2.8%), and monoterpene hydrocarbons (0.9%). This study revealed that the roots of C. odorata produced different chemotypes other than leaves oil. This is the first report on the essential oil composition of the roots of C. odorata .'),(1995,'10.1155/2013/279726','<i>Eugenia uniflora</i>L. Essential Oil as a Potential Anti-<i>Leishmania</i>Agent: Effects on<i>Leishmania amazonensis</i>and Possible Mechanisms of Action','Evidence-based Complementary and Alternative Medicine',2013,'https://doi.org/10.1155/2013/279726',101,'https://openalex.org/W1980065052','Eugenia uniflora L. is a member of the Myrtaceae family and is commonly known as Brazilian cherry tree. In this study, we evaluated the chemical composition of Eugenia uniflora L. essential oil (EuEO) by using gas chromatography-mass spectrometry (GC-MS) and assessed its anti-Leishmania activity. We also explored the potential mechanisms of action and cytotoxicity of EuEO. Thirty-two compounds were identified, which constituted 92.65% of the total oil composition. The most abundant components were sesquiterpenes (91.92%), with curzerene (47.3%), γ -elemene (14.25%), and trans- β -elemenone (10.4%) being the major constituents. The bioactivity shown by EuEO against promastigotes (IC50, 3.04 μ g·mL(-1)) and amastigotes (IC50, 1.92 μ g·mL(-1)) suggested significant anti-Leishmania activity. In the cytotoxicity determination, EuEO was 20 times more toxic to amastigotes than to macrophages. Hemolytic activity was 63.22% at the highest concentration tested (400 μ g·mL(-1)); however, there appeared to be no toxicity at 50 μ g·mL(-1). While the data show that EuEO activity is not mediated by nitric oxide production, they do suggest that macrophage activation may be involved in EuEO anti-Leishmania activity, as evidenced by increases in both the phagocytic capacity and the lysosomal activity. More studies are needed to determine in vivo activity as well as additional mechanisms of the anti-Leishmania activity.'),(1996,'10.1155/2014/963729','Chemical Constituents and Insecticidal Activities of the Essential Oil of<i>Cinnamomum camphora</i>Leaves against<i>Lasioderma serricorne</i>','Journal of Chemistry',2014,'https://doi.org/10.1155/2014/963729',45,'https://openalex.org/W2029644888','During our screening program for agrochemicals from Chinese medicinal herbs and wild plants, the essential oil of Cinnamomum camphora leaves was found to possess strong fumigant and contact toxicity against Lasioderma serricorne adults with LC 50 /LD 50 values of 2.5 mg/L air and 21.25 μ g/adult, respectively. The essential oil obtained by hydrodistillation was investigated by GC and GC-MS. The main components of the essential oil were identified to be D -camphor (40.54%), linalool (22.92%), cineole (11.26%), and 3,7,11-trimethyl-3-hydroxy-6,10-dodecadien-1-yl acetate (4.50%). Bioactivity-directed chromatographic separation on repeated silica gel columns led to the isolation of D -camphor and linalool. D -camphor and linalool showed strong fumigant toxicity (LC 50 = 2.36 and 18.04 mg/L air, resp.) and contact toxicity (LD 50 = 13.44 and 12.74 μ g/adult, resp.) against L. serricorne . The results indicate that the essential oil of C. camphora and its active compounds had the potential to be developed as natural fumigants and insecticides for control of L. serricorne.'),(1997,'10.1155/2015/506413','In Vitro Pharmacological Activities and GC-MS Analysis of Different Solvent Extracts of<i>Lantana camara</i>Leaves Collected from Tropical Region of Malaysia','Evidence-based Complementary and Alternative Medicine',2015,'https://doi.org/10.1155/2015/506413',86,'https://openalex.org/W2195389703','We investigated the effect of different solvents (ethyl acetate, methanol, acetone, and chloroform) on the extraction of phytoconstituents from Lantana camara leaves and their antioxidant and antibacterial activities. Further, GC-MS analysis was carried out to identify the bioactive chemical constituents occurring in the active extract. The results revealed the presence of various phytocompounds in the extracts. The methanol solvent recovered higher extractable compounds (14.4% of yield) and contained the highest phenolic (92.8 mg GAE/g) and flavonoid (26.5 mg RE/g) content. DPPH radical scavenging assay showed the IC50 value of 165, 200, 245, and 440 μg/mL for methanol, ethyl acetate, acetone, and chloroform extracts, respectively. The hydroxyl scavenging activity test showed the IC50 value of 110, 240, 300, and 510 μg/mL for methanol, ethyl acetate, acetone, and chloroform extracts, respectively. Gram negative bacterial pathogens (E. coli and K. pneumoniae) were more susceptible to all extracts compared to Gram positive bacteria (M. luteus, B. subtilis, and S. aureus). Methanol extract had the highest inhibition activity against all the tested microbes. Moreover, methanolic extract of L. camara contained 32 bioactive components as revealed by GC-MS study. The identified major compounds included hexadecanoic acid (5.197%), phytol (4.528%), caryophyllene oxide (4.605%), and 9,12,15-octadecatrienoic acid, methyl ester, (Z,Z,Z)- (3.751%).'),(1998,'10.1155/2016/2482930','Phytochemical Composition and Biological Activities of Selected Wild Berries (<i>Rubus moluccanus</i> L., <i>R. fraxinifolius</i> Poir., and <i>R. alpestris</i> Blume)','Evidence-based Complementary and Alternative Medicine',2016,'https://doi.org/10.1155/2016/2482930',41,'https://openalex.org/W2465869192','Berries, from the genus Rubus, are among the vital components in a healthy diet. In this study, 80% methanol extracts from the three wild Rubus species (Rubus moluccanus L., Rubus fraxinifolius Poir., and Rubus alpestris Blume) were evaluated for their phytochemical contents (total phenolics, flavonoid, anthocyanin, and carotenoid content), antioxidant (DPPH, FRAP, and ABTS assays), antiacetylcholinesterase, and antibacterial activities. GC-MS was used for quantification of naturally occurring phytochemicals. The results showed that R. alpestris contained the highest total phenolic [24.25 ± 0.1 mg gallic acid equivalent (GAE)/g] and carotenoid content [21.86 ± 0.63 mg β-carotene equivalents (BC)/g], as well as the highest DPPH scavenging and FRAP activities. The highest total flavonoid [18.17 ± 0.20 mg catechin equivalents (CE)/g] and anthocyanin content [36.96 ± 0.39 mg cyanidin-3-glucoside equivalents (c-3-gE)/g] have been shown by R. moluccanus. For antibacterial assays, R. moluccanus and R. alpestris extracts showed mild inhibition towards Bacillus subtilis, Staphylococcus aureus, Escherichia coli, and Salmonella enteritidis. Anticholinesterase activity for all extracts was in the range of 23-26%. The GC-MS analysis revealed the presence of at least 12, 21, and 7 different organic compounds in 80% methanol extracts of R. alpestris, R. moluccanus, and R. fraxinifolius, respectively, which might contribute to the bioactivity.'),(1999,'10.1155/2018/9363868','Potential Antiproliferative Activity and Evaluation of Essential Oil Composition of the Aerial Parts of <i>Tamarix aphylla</i> (L.) H.Karst.: A Wild Grown Medicinal Plant in Jordan','Evidence-based Complementary and Alternative Medicine',2018,'https://doi.org/10.1155/2018/9363868',15,'https://openalex.org/W2808851868','Essential (volatile) oil from aerial parts of Tamarix aphylla (L.) H.Karst. (Tamaricaceae) grown wild in Jordan was hydrodistilled by Clevenger apparatus and analyzed by means of GC and GCâMS techniques. In vitro screening of potential cytotoxicity of the aqueous (AE) and ethanol (EE) extracts was also evaluated against human breast adenocarcinoma (MCFâ7), colorectal adenocarcinoma (Cacoâ2), and pancreatic carcinoma (Pancâ1) cancer cell lines as well as normal human fibroblasts. GCâMS analysis of T. aphylla EO revealed its richness in nonterpenoid nonaromatic hydrocarbons (52.39%), with predominance of 6,10,14âtrimethylâ2âpentadecanone as the principal component. Biologically, the plant extracts exhibited cytotoxicity effects in doseâdependent manner against most of the tested cell lines, but potent effects were only predicted against MCFâ7 cells with IC 50 values of 2.17 ± 0.10 and 26.65 ± 3.09 μ g/mL for T. aphylla AE and EE, respectively. T. aphylla AE demonstrated a comparable cytotoxic effect with that offered by the control drug cisplatin (IC 50 value of 1.17 ± 0.13 μ g/mL), even with higher safety profile against normal fibroblast cells (IC 50 values of T. aphylla AE versus cisplatin: 79.99 ± 4.90 versus 9.08 ± 0.29 μ g/mL). T. aphylla extracts could be a valuable source for cytotoxic agents with high safety and selective cytotoxicity profiles. Unfortunately, no antiproliferative potential against Cacoâ2 or Pancâ1 cancer cell lines was detected at a concentration less than 30 μ g/mL.'),(2000,'10.1155/2019/5256781','<i>Schinus terebinthifolius</i>Essential Oil Attenuates Scopolamine-Induced Memory Deficits via Cholinergic Modulation and Antioxidant Properties in a Zebrafish Model','Evidence-based Complementary and Alternative Medicine',2019,'https://doi.org/10.1155/2019/5256781',62,'https://openalex.org/W2990001111','Schinus terebinthifolius is a plant well recognized for its therapeutic profile such as anti-inflammatory and antitumor activities, promoting antibacterial activity and antioxidant and antidiabetic properties. This study aimed at examining whether Schinus terebinthifolius memory-enhancing activities are mediated by cholinergic and brain antioxidant systems in a scopolamine zebrafish model. Schinus terebinthifolius essential oil (10, 25, and 50 μ L/L) was delivered to zebrafish by immersion in water for 8 days. Memory deficits were induced by scopolamine (100 μ M) administration. Zebrafish were divided into seven groups ( n = 15/group): vehicle group, scopolamine (100 μ M) group, Schinus terebinthifolius essential oil groups (STF; 10, 25, and 50 μ L/L), the imipramine group (IMP; 20 mg/L, as the positive control in the NTT test), and the donepezil group (DP; 10 mg/L, as the positive control in the Y-maze test). Memory status was estimated by the novel tank diving test (NTT) and the Y-maze test and finally was validated by comparison with imipramine (20 mg/L) and donepezil (10 mg/L). Gas chromatography-mass spectrometry (GC-MS) was used to detect oil compounds. Brain levels of acetylcholinesterase (AChE) and antioxidant enzymes were measured. After being exposed to Schinus terebinthifolius essential oil, the scopolamine zebrafish exhibited an improvement of memory processes in the NTT and Y-maze tests. The essential oil attenuated the elevated level of AChE and brain oxidative stress. Schinus terebinthifolius essential oil was found to support memory formation through the inhibition of the AChE activity and decreasing oxidative stress in the scopolamine-treated zebrafish brains.'),(2001,'10.1155/2022/5426050','Chemical Compositions of Essential Oil from Aerial Parts of Cyclospermum leptophyllum and Its Application as Antibacterial Activity against Some Food Spoilage Bacteria','Journal of Chemistry',2022,'https://doi.org/10.1155/2022/5426050',12,'https://openalex.org/W4300773210','Cyclospermum leptophyllum is plant species known for its medicinal value and pleasant aroma. The aerial part and plant seeds are traditionally used as food additives as a spice. This study aims to isolate the chemical constituents of essential oil of the aerial part of the plant and study their potential antibacterial activities against some food contaminating bacteria. The essential oil of C. leptophyllum (CSEO) was isolated from aerial parts of the plant species and studied using GC-MS and FTIR techniques. The first four major chemical constituents determined from GC-MS analysis of CSEO (for peak area % â¥ 1.15%) were 2,5-dimethoxy-p-cymene (87.09%), 2-methoxy-1-methyl-4-(1-methylethyl) benzene (3.09%), 2-methoxy-4-methyl-1-(1-methylethyl) benzene (1.71%), and humulene (1.15%). 60%, 30%, 15%, 7.5%, and 3.75% of CSEO solutions were prepared and evaluated for their potential antibacterial activities against six food spoilage pathogenic bacterial strains. Three Gram-positive strains: Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (ATCC 12228), Streptococcus agalactiae (ATCC 12386) and three Gram-negative strains: Escherichia coli (ATCC 25922), Proteus mirabilis (ATCC 35659), and Pseudomonas aeruginosa (ATCC 27853) were used as test microorganisms. Compared to ciprofloxacin, a positive control, the promising antibacterial activity was observed for CSEO against S. aureus at minimum and maximum test solutions as the values of the zone of inhibition diameter (ZID, mm) were recorded as 14.33 ± 0.58 for 3.75% CSEO solution and 30.67 ± 0.58 for 60% CSEO solution. Tests of CSEO solutions generally showed stronger antibacterial activities against Gram-positive than Gram-negative strains. Therefore, CSEO contains potent chemical constituents that might be applicable in treating pathogenic bacterial species.'),(2002,'10.1155/2023/7335134','Study of the Variability of the Chemical Profile, and Biological Activity Approaches of Hedychium coronarium J. Koenig Essential Oil from Different Habitats of Uttarakhand, India','Journal of Food Quality',2023,'https://doi.org/10.1155/2023/7335134',8,'https://openalex.org/W4379743602','The objective of the current study was to evaluate the altitudinal variability in chemical compounds, nematicidal, insecticidal, herbicidal, and antifungal activity of the essential oils of H. coronarium collected from four different habitats of Tarai and Kumaun region of Uttarakhand. Essential oils were hydro-distilled from rhizomes of H. coronarium, and their yield varied from 0.05 to 0.25% (v/w). Based on GC-MS analysis, the major compounds observed were 1, 8-cineole (12.21â18.27%), coronarin E (10.20â14%), α-terpineol (5.32â10.13%), terpinen-4-ol (2.20â4.67%), α-pinene (4.90â8.77%), Z-caryophyllene (4.67â12.29%), and linalool (1.96â4.62%). To visually observe the variation in the oil composition profile of essential oils, heat map clustering, Venn diagram, and principal component analysis (PCA) were performed. To evaluate the pesticidal properties, the essential oils were tested under laboratory conditions. Additionally, significant nematicidal activity was demonstrated by essential oils against Meloidogyne incognita, good insecticidal activity against Spodoptera litura, and moderate herbicidal activity on Raphanus raphanistrum subsp. sativus, and effective antifungal activity against Fusarium oxysporum and Curvularia lunata was observed in the current investigation.'),(2003,'10.11606/d.9.2001.tde-13012012-111440','Estudo Biofarmacognóstico \'Campomanesia phaea (O. Berg.) Landrum\'. Myrtaceae\".','NA',2001,'https://doi.org/10.11606/d.9.2001.tde-13012012-111440',2,'https://openalex.org/W2538352650','\n Campomanesia phaea L, espécie da família Myrtaceae, popularmente denominada de \\\'cambuci\\\' foi estudada através de uma abordagem botânica, química e farmacológica. A planta foi coletada e é cultivada no Instituto de Agronomia da Estação Experimental de Ubatuba no litoral norte do Estado de São Paulo. O estudo morfo-anatômico das folhas foi realizado conjuntamente com uma triagem fitoquímica de seus constituintes químicos mais importantes e seus extratos foram ensaiados farmacológica e microbiologicamente. O ensaio de toxicidade aguda foi realizado em camundongos e a avaliação da atividade antimicrobiana foi realizada com o extrato liofilizado contra bactérias Staphylococcus aureus (ATCC 6538) e Pseudomonas aeruginosa (ATCC 9027), em levedura, Candida albicans (ATCC 10231), e bolor, Aspergillus niger (ATCC 16404). O óleo volátil presente nas folhas da espécie, foi extraído por hidrodestilação em aparelho de Clevenger. O óleo bruto obtido, foi submetido à análise para identificação de seus componentes por cromatografia em camada delgada preparativa, cromatografia a gás e cromatografia a gás acoplada à espectrometria de massa (CG/EM) com banco de dados. Dentre 38 componentes reconhecidos, 34 foram identificados. A planta é rica em óleo essencial contendo linalol (11,1%), componente de grande valor comercial para a indústria de cosméticos e na indústria farmacêutica, óxido de cariofileno (11,8%), beta-cariofileno (6,3%), beta-selineno (6,9%) e alfa-cadinol (7,5%).\n'),(2004,'10.11606/d.9.2002.tde-17032015-085231','Caracterização farmacognóstica de Campomanesia xanthocarpa Myrtaceae ou Caracterização farmacognóstica de Campomanesia xanthocarpa Berg Myrtaceae','NA',2002,'https://doi.org/10.11606/d.9.2002.tde-17032015-085231',1,'https://openalex.org/W2464973737','\n Campomanesia xanthocarpa Berg, espécie pertencente à família Myrtaceae, é conhecida popularmente como gabiroba. Diversas propriedades terapêuticas são atribuídas às espécies de Campomanesia, tais como, combate à disenteria, febre, cistites e uretrites. O presente trabalho objetiva contribuir para elaboração de monografia da espécie, através do estudo químico e farmacológico do extrato hidroalcoólico liofilizado e da droga vegetal constituída de folhas. Os caracteres farmacobotânicos da droga vegetal são apresentados com o intuito de auxiliar a diagnose. Dentre as principais características macroscópicas das folhas desidratadas podem ser citadas: ondulação nas bordas; pontos translúcidos na lâmina, tipo de venação, forma da lâmina e dos pecíolos, e odor aromático. As características anatômicas que se destacaram são: mesofilo dorsiventral; grandes idioblastos contendo cristal prismático na região paliçádica; predominância de estômatos anomocíticos nas folhas hipoestomáticas; cavidades secretoras globosas, associadas a ambas as superfícies, recobertas por células dispostas aos pares em que a parede comissural mostra-se reta, sinuosa ou de \\\"zig-zag\\\"; feixe vascular bicolateral e sistema disposto em arco aberto; cristais prismáticos na região floemática. Fotomicrografias ilustraram o trabalho. A triagem fitoquímica da droga vegetal e do extrato liofilizado (EHA) indicou a presença de flavonóides, taninos, saponinas e óleo essencial. O teor de óleo essencial nas folhas frescas, foi de 0,11 %. Linalol (29%) e globulol (20%) foram identificados como os principais componentes do óleo. O teor de taninos na droga foi de 2,86 % e no extrato EHA, de 8,49 %. O teor de saponinas na droga foi de 6,27 % e no extrato EHA de 16%. O extrato apresentou elevada atividade antioxidante no modelo de medida de produção de malonildialdeído, com Q1/2 =0,2891 &amp;#181;g/mL. No ensaio da inibição da lipoperoxidação, induzida por sulfato de cobre, o extrato EHA reduziu significativamente o tempo de indução (\\\"Lag-time\\\") e o tempo de terminação (\\\"Peak-time\\\") da oxidabilidade de lipoproteínas de baixa densidade (LDL). O extrato EHA apresentou atividade antiúlcera no modelo de indução aguda por ácido clorídrico em etanol, com percentual de proteção de 62%. O extrato EHA apresentou atividade antimicrobiana com: CMI &amp;#62;1.000 e &amp;#60;500 &amp;#181;g/mL em relação a Staphylococcus aureus; CMI &amp;#60;500 e &amp;#62;100 &amp;#181;g/mL para Salmonella cholerasuis e CMI &amp;#60;1.000 e &amp;#62;500 &amp;#181;g/mL em relação a Candida albicans. O extrato EHA mostrou atividade citotóxica no ensaio da letalidade de artêmias, com DL50 de 0,503 mg/mL. O extrato EHA não apresentou toxicidade no ensaio de toxicidade aguda, na dose de 5g/kg de peso do animal, por via oral.\n'),(2005,'10.1177/1934578X0700200603','Saponins and Volatile Constituents from <i>Lonicera japonica</i> Growing in the Western Himalayan Region of India','Natural Product Communications',2007,'https://doi.org/10.1177/1934578x0700200603',3,'https://openalex.org/W2929846651','Chemical investigation of the leaves and fresh flowers of Lonicera japonica lead to the isolation of a new pentacyclic triterpene saponin, 3- O-[α-L-rhamnopyranosyl-(1â2)-β-D-xylopyranosyl]-hedragenin (1) along with two known saponins, 3- O-[α-L-arabinopyranosyl]-hedragenin (2) and 3- O-[α-L-rhamnopyranosyl-(1â2)-α-L-arabinopyranosyl]-hedragenin (3), two fatty acid esters, methyl (Z,Z) 9,12-octadecadienoate (methyl linoleate) (4) and methyl (Z,Z,Z) 9,12,15-octadecatrienoate (methyl linolineate) (5) and two long chain hydrocarbons, octadecane (6) and heneicosane (7). The structures were established on the basis of IR, 1D- and 2D-NMR (HMQC and HMBC) spectroscopic and ESI-QTOF-MS/MS analysis. Simultaneously, the volatile composition of fresh flowers of L. japonica, analyzed by GC/MS, indicated the presence of two long chain hydrocarbons, heneicosane (37.5%) and octadecane (34.5%) as major constituents. Other metabolites characterized were fatty acids and their esters, such as palmitic acid (1.7%), linolenic acid (2.5 %), linoleic acid (1.3%), methyl palmitate (2.3%), methyl 9,12-octadecadienoate (4.5%) and methyl ( Z,Z,Z)-9,12,15-octadecatrienoate, along with oxygenated monoterpenes and sesquiterpenes, namely linalool, cis-linalool oxide, terpine-4-ol and trans-nerolidol.'),(2006,'10.1177/1934578X0800301031','Comparative Analysis of the Essential Oils from two Asteraceous Plants Found in Nigeria, <i>Acanthospermum Hispidum</i> and <i>Tithonia Diversifolia</i>','Natural Product Communications',2008,'https://doi.org/10.1177/1934578x0800301031',5,'https://openalex.org/W2935318900','The essential oils from two members of the Asteraceae ( Acanthospermum hispidum DC. aerial parts, and leaves of Tithonia diversifolia (Hemsley) A. Gray), growing wild in Osun State, Nigeria, have been characterised by combined gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) analyses. Twenty-nine components have been fully identified and grouped into monoterpene hydrocarbons (22.2%), oxygenated monoterpenes (4.6%), sesquiterpenes hydrocarbons (58.2%) and oxygenated sesquiterpenes (10.8%) in A. hispidum. The main constituents of the oil were β-caryophyllene (28.0%), α-pinene (15.9%) and bicyclogermacrene (11.0%) among the hydrocarbon compounds, and bisabolol (8.9%) and carvacrol methyl ether (4.1%) among the oxygenated components. Tithonia diversifolia essential oil comprised seventeen components and was characterised by a predominant content of monoterpene hydrocarbons (87.9%), cis-β-ocimene (43.7%), α-pinene (28.6%) and limonene (12.0%) being the main compounds. Sesquiterpenes represented ca. 10% oil, as sum of hydrocarbons and oxygenated components. A new chemotype is established for T. diversifolia, while the Nigerian A. hispidum is being reported for the first time as a new source of essential oil with some distinction in composition from those of other sources.'),(2007,'10.1177/1934578X0900400123','Essential Oil Compositions of Three <i>Lantana</i> Species from Monteverde, Costa Rica','Natural Product Communications',2009,'https://doi.org/10.1177/1934578x0900400123',9,'https://openalex.org/W199044098','The leaf essential oils of three species of Lantana from Monteverde, Costa Rica (L. camara, L. velutina, and L. hirta) were obtained by hydrodistillation and the chemical compositions determined by GC-MS analysis. The principal components of L. velutina were limonene (21.4%), (E)-caryophyllene (23.4%) and bicyclogermacrene (8.2%). The leaf oil composition of L. hirta was relatively simple, containing mostly 1-octen-3-ol (64.6%), germacrene D (24.5%), and (E)-caryophyllene (10.9%). Two different samples of L. camara, however, yielded vastly different leaf oil compositions; one was dominated by sesquiterpenes, (E)-caryophyllene (30.3%), gamma-muurolene (27.2%), bicyclogermacrene (24.4%) and beta-elemene (14.2%); the second sample, on the other hand, was composed largely of fatty acid-derivatives, (Z)-3-hexenol and 1-octen-3-ol. The very different compositions for L. camara are consistent with the wide diversity of chemical compositions observed in previous reports for this species.'),(2008,'10.1177/1934578X1000500134','Biological Activities of Bellis perennis Volatiles and Extracts','Natural Product Communications',2010,'https://doi.org/10.1177/1934578x1000500134',21,'https://openalex.org/W2415245458','Different parts of Bellis perennis were subjected to hydrodistillation and the products were subsequently analyzed by GC and GC/MS. Aqueous and methanol extracts were prepared from the aerial parts. Antioxidant [1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging, reducing activity, total antioxidant] and antimicrobial activity of the plant materials were studied. The aqueous extracts showed higher DPPH scavenging activity (85.8% at 102.5 microg/mL) than the methanol extract. Reducing power was also observed for both tested extracts, where the formation of linoleic acid peroxides was more for the aqueous extract than the methanol extract. Antimicrobial activities of all plant materials were evaluated at varying concentrations against a panel of pathogens, but without pronounced inhibitory effect.'),(2009,'10.1177/1934578X1100600727','Chemical Composition and Antibacterial Activity of the Essential Oil of <i>Lantana Camara Var. Moritziana</i>','Natural Product Communications',2011,'https://doi.org/10.1177/1934578x1100600727',22,'https://openalex.org/W2409422170','The essential oil obtained from the leaves of Lantana camara var. moritziana (Otto & Dietr.) López-Palacios collected at Rubio, Táchira State, Venezuela, was obtained by hydrodistillation in a Clevenger trap (0.1% yield). The oil was analyzed by gas chromatography-mass spectrometry (GC/MS) on HP GC-MS System, model 5973, identifying 33 compounds (97.1%) of which the major components were germacrene D (31.0%), followed by beta-caryophyllene (14.8%), a-phellandrene (6.7%), limonene (5.7%) and 1,8-cineole (5.2%). Evaluation of the antibacterial activity by agar diffusion method with discs against international reference bacteria (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Salmonella Typhi, Pseudomonas aeruginosa) showed growing inhibition of E. faecalis and S. aureus at MIC of 350 mg/mL and 400 mg/mL, respectively.'),(2010,'10.1177/1934578X1200700736','Chemical Composition and <i>in vitro</i> Antimicrobial Activity of the Essential Oil of the Flowers of <i>Tridax procumbens</i>','Natural Product Communications',2012,'https://doi.org/10.1177/1934578x1200700736',14,'https://openalex.org/W95590365','The essential oil of the flowers of Tridax procumbens L. was obtained by hydro-distillation and analyzed by gas chromatography equipped with a flame ionization detector (GC-FID) and gas chromatography coupled with mass spectrometry (GC/MS). Twenty-six compounds were identified, which comprised 90.6% of the total constituents. The most abundant compound was ( Z)-falcarinol (25.9%), followed by α-selinene (15.3%), limonene (8.3%) and zerumbone (4.3%). Antimicrobial activity was tested against six Gram-positive and eight Gram-negative bacteria, and three fungi. The oil was active against the tested Gram-positive bacteria at a concentration range of 0.14 ± 0.03 - 0.57±0.05 mg/mL, while 0.67 ± 0.12 - 4.58 ± 0.41 mg/mL was effective against the studied Gram-negative bacteria. Remarkable antifungal activity was found against the tested fungi at a concentration range of 0.06 ± 0.008 - 0.10 ± 0.01 mg/mL.'),(2011,'10.1177/1934578X1300800229','Essential Oils from the Leaves of Six Medicinal Plants of Nigeria','Natural Product Communications',2013,'https://doi.org/10.1177/1934578x1300800229',16,'https://openalex.org/W10597972','The chemistry of Cassia siamea L., C. occidentalis L. (Fabaceae), Cnestis ferruginea Vahl ex DC (Connaraceae), Anthocleista djalonensis A. Chev (Loganiaceae), Solanum torvum Swartz and S. erianthum G. Don (Solanaceae) volatiles grown in Nigeria have been studied. The essential oils were obtained by hydrodistillation and analyzed by GC and GC-MS. The main compounds of C. siamea were (E)-geranyl acetone (5.8%), 1-octen-3-ol (5.8%), linalool (7.8%), iso-italicene (15.4%) and (E)-beta-damascenone (11.0%). On the other hand, C. occidentalis consisted mainly of (E)-geranyl acetone (8.0%), hexahydrofarnesylacetone (24.0%) and (E)-phytol acetate (40.7%). The oil of C. ferruginea was comprised mainly of (E)-geranyl acetone (13.7%), (E)-alpha-ionone (9.5%), phytol (5.8%), pentadecanal (6.1%) and 1-octen-3-ol (5.5%). The main compounds of A. djalonensis were alpha-humulene (31.9%), beta-caryophyllene (17.8%), humulene epoxide II (12.7%) and caryophyllene oxide (5.9%). The main volatiles of S. torvum were (E)-phytol acetate (38.7%), pentadecanal (25.3%) and (E)-geranyl acetone (5.0%). Apart from methyl salicylate (4.5%), tetradecanal (2.2%), 2-pentyl furan (1.8%), hexahydrofarnesylacetone (1.6%) and hexadecanal (1.1%), all other compounds were either present in trace quantity or in amounts less than 1%. On the other hand, alpha-humulene (46.6%) and beta-caryophyllene (20.6%) were the compounds occurring in higher quantities in S. erianthum. The volatile oil contents of Cassia siamea, Cnestis ferruginea, Anthocleista djalonensis and Solanum torvum are being reported for the first time.'),(2012,'10.1177/1934578X1300800935','Chemical Analysis and Antioxidant Activity of the Essential Oils of Three Piperaceae Species Growing in the Central Region of Cuba','Natural Product Communications',2013,'https://doi.org/10.1177/1934578x1300800935',22,'https://openalex.org/W2416198235','The present study describes the phytochemical profile and antioxidant activity of the essential oils of three Piperaceae species collected in the central region of Cuba. The essential oils of Piper aduncum, P. auritum and P. umbellatum leaves, obtained by hydrodistillation, were analyzed by gas chromatography-mass spectrometry. The main components of P. aduncum oil were piperitone (34%), camphor (17.1%), camphene (10.9%), 1,8-cineol (8.7%) and viridiflorol (7.4%), whereas that of P. auritum and P. umbellatum was safrole (71.8 and 26.4%, respectively). The antioxidant properties of the essential oils were also evaluated using several assays for radical scavenging ability (DPPH test and reducing power) and inhibition of lipid oxidation (ferric thiocyanate method and evaluation against Cucurbita seed oil by peroxide, thiobarbituric acid and p-anisidine methods). P. auritum showed the strongest antioxidant activity among the Piper species investigated, but lower than those of butylated hydroxyanisol and propyl gallate.'),(2013,'10.1177/1934578X1601101233','Phenylpropanoid-rich Essential Oils of <i>Piper</i> Species from the Amazon and their Antifungal and Anti-cholinesterase Activities','Natural Product Communications',2016,'https://doi.org/10.1177/1934578x1601101233',22,'https://openalex.org/W2933860304','The essential oils (EOs) from aerial parts of Piper aduncum, P. callosuin and P. marginatum, collected from the Amazon region of Brazil, were analyzed by GC-MS and then evaluated for their antifungal and anticholinesterase activities. The essential oils were dominated by phenylpropanoids, such as dillapiole (73.0%) in P. aduncum, safrole (66.0%) in P. callosum and 3,4-methylenedioxypropiophenone (21.8%) in P. inarginatum. The analyzed oils showed low to moderate antifungal activity; with detection limits (DL) from 10 to 100 pg against Cladosporium cladosporioides and C. sphareospermum. In the anticholinesterase (AChE) evaluation, the oils of P. callosum (DL = 0.01 ng) and P. marginatum (DL = 0.01 ng) were one hundred times more potent than the standard physostigmine (DL = 1.0 ng). Molecular docking analysis showed that phenylpropanoids docked reasonably well with acetyleholinesterase and may be responsible for the anti-AChE activities of the Piper EOs. This is the first presentation about acetylcholinesterase inhibition by methylenedioxyphenyl-propanoids.'),(2014,'10.1177/1934578X1701200525','Antioxidant Activity and Chemical Composition of Essential Oils of some Aromatic and Medicinal Plants from Albania','Natural Product Communications',2017,'https://doi.org/10.1177/1934578x1701200525',31,'https://openalex.org/W2927468375','The chemical compositions have been investigated of the volatile oils of nine populations of six species from Albania, namely Artemisia absinthium, Calamintha nepeta, Hypericum perforatum, Sideritis raeseri subsp. raeseri, Origanum vulgare subsp. hirtum from two wild .populations, and Salvia officinalis (sage) from two wild and one cultivated population,. The essential oils were obtained by hydrodistillation and their analyses were performed by GC-MS. The major constituents were: A. absinthium: neryl isovalerate (19.5%), geranyl isobutanoate (16.4%) and carvacrol (8.8%); C. nepeta: pulegone (31.7%), spathulenol (20.0%) and isomenthone (12.7%); H. perforatum: caryophyllene oxide (31.0%), δ-selinene (10.5%) and carvacrol (10.4%); O. vulgare: carvacrol (81.0, 78.6%), y-terpinene (5.5, 7.1%) and p-cymene (4.9, 4.1%) for 0. vulgare originating from Tepelena. and.Vlora, respectively; S. raeseri: carvacrol (36.7%), caryophyllene oxide (17.8%), p-caryphyllene (8.7%), spathulenol (7.7%) and myrtenol (6.4%); S. officinalis: camphor (40.2, 47.8, 45.9%), c-thujone .(19.2, 22.2, 13.7%), eucalyptol (5.4, 2.6, 6.0%), camphene (5.8, 6.1, 3.9, %), borneol (2.1, 2.9, 5.7%) and bornyl acetate (3.3, 1.4, 5.6%) for samples originating from Tepelena, Tirana and Vlora, respectively. The essential oils were also tested for their free radical scavenging activity using the following in vitro assays: i) interaction with the free stable radical of DPPH (1,1-diphenyl-2-picrylhydrazyl), and ii) inhibition of linoleic acid-peroxidation with 2,2\'-azobis- 2-methyl-propanimidamide, dihydrochloride (AAPH). Finally, their inhibitory activity toward soybean lipoxygenase was evaluated, using linoleic acid as substrate.The essential oil of 0. vulgare (OV-VL) presented the highest interaction with the stable radical DPPH (76.5%), followed by that of A. absinthium (54.7%). O. vulgare (OV-TP) and A. absinthium showed high anti-lipid peroxidation activity, 97.5% and 96.5%, respectively, higher than that of the reference compound trolox (73.0%). Only the tested sample of O. vulgare (OV-VL) significantly inhibited soybean lipoxygenase (54.2%).'),(2015,'10.1177/1934578X1701200842','Aroma Profile and Antioxidant Activity of Essential Oil from <i>Alpinia zerumbet</i>','Natural Product Communications',2017,'https://doi.org/10.1177/1934578x1701200842',6,'https://openalex.org/W2925471796','The essential oil of A. zerumbet, obtained from the leaves through steam distillation, has a distinct aroma and shows antioxidant activity. In this study, we evaluated the yields, antioxidant activity, and volatile compound composition of essential oils extracted from the leaves of A. zerumbet to better understand how these characteristics may vary among individual plants, and how they may differ with location of growth and season in which leaves are harvested. Gas chromatographyâmass spectrometry (GC/MS) and principal component analysis (PCA) revealed that chemical composition in each individual plant was not affected by harvest season or growth area. Furthermore, GC/MS and antioxidant activity assays revealed that although the antioxidant activity and yield of these essential oils differed significantly between individual plants and collecting seasons, there was a strong inverse correlation between the yields of essential oils and their antioxidant activity. The yield, the major volatile compound compositions, the enantiomeric ratio of the few monoterpenes, and the antioxidant activities of A. zerumbet essential oil varied significantly among individual plants, and probably reflected the genetic variability within the species. This suggests the plausibility of selecting lineages of A. zerumbet to optimize future production of valuable essential oils.'),(2016,'10.1177/1934578X1801300919','Chemical Composition and Antifungal Activity of the Essential Oil of <i>Cotinus coggygria</i> from Marche Region (Italy)','Natural Product Communications',2018,'https://doi.org/10.1177/1934578x1801300919',3,'https://openalex.org/W2928877933','The present study reports the results of gas chromatography-mass spectrometry (GC/MS) analyses of the essential oil from flowering aerial parts of Cotinus coggygria Scoop. (Anacardiaceae), as well as its in vitro antifungal activity against nine plant pathogenic fungi. Moreover, the essential oil was evaluated for its antifungal activity using the agar dilution method, and also MIC s (minimum inhibitory concentrations) and MFC s (minimum fungicidal concentrations) were determined. The major compounds identified by GC-MS were limonene (49.2%), (Z)-β-ocimene (13.6%), α-pinene (8.8%) and (E)-β-ocimene (5.9%). The oil showed in vitro antifungal activity against some species of the Fusarium genus, Botrytis cinerea, and Alternaria solani. Our study indicates that the oil of C. coggygria could be used as a control agent for plant pathogenic fungi in natural formulations.'),(2017,'10.1177/1934578X19842703','Volatile Constituents of the Leaves of Kalanchoe pinnata From the Venezuelan Andes','Natural Product Communications',2019,'https://doi.org/10.1177/1934578x19842703',5,'https://openalex.org/W2946942893','The essential oil from the leaves of Kalanchoe pinnata (Lam.) Pers. (Crassulaceae), collected in the Venezuelan Andes, was obtained by hydrodistillation and its composition determined by gas chromatography (GC) and gas chromatography/mass spectrometry (GC/MS). Nineteen compounds were identified, representing 95.2% of the oil. The most abundant components were α-curcumene (44.7%), 1-octen-3-ol (18.1%), β-curcumene (4.9%), and β-caryophyllene (3.7%).'),(2018,'10.1177/1934578X19856257','Phytochemical and Micromorphological Characterization of Croatian Populations of <i>Erodium cicutarium</i>','Natural Product Communications',2019,'https://doi.org/10.1177/1934578x19856257',11,'https://openalex.org/W2954897284','The aim of this study included the phytochemical screening of extracts and essential oil of Erodium cicutarium (L.) LâHér. ex Aiton (Geraniaceae), a native traditional medicinal plant from Croatia, as well as a highly detailed micromorphological characterization of its aerial parts. The contents of total polyphenols and tannins (TP and T), total flavonoids (TF), and total hydroxycinnamic derivatives (THD) in plant extracts were quantified in plant material from 4 localities (Plitvice, Podvinje, Buzin, and Trešnjevka). The contents of TP, T, TF, and THD significantly varied depending on the collection site, and were in the range of 4.78%-12.85% (TP), 3.23%-5.80% (T), 0.42%-1.09% (TF), and 1.08%-2.59% (THD) of dry weight of plant material, with the Plitvice collection having the highest polyphenol content. GC-MS analysis of the essential oils showed a similarity in composition of the major compounds from all investigated populations. Fifty compounds were identified in all 4 investigated oils (90.4%-96.7% of total oil) and classified into 7 structural classes, with hydrocarbons (59.8%-65.7%) as the main class of constituents. Two types of trichomes, nonglandular and glandular, were observed on the calyces, leaves, and stems, including 3 capitate trichome types. The bioactive substances and micromorphological characterization of Croatian populations of E. cicutarium were investigated for the first time. In general, the scanning electron microscopy imaging of Erodium cicitarium trichomes has not been reported before.'),(2019,'10.1177/1934578X221099971','Chemical Composition and <i>In Vitro</i> Anti-Wood-Decay Fungal Activities of <i>Dysphania ambrosioides</i> Leaf Essential Oil From Taiwan','Natural Product Communications',2022,'https://doi.org/10.1177/1934578x221099971',5,'https://openalex.org/W4229452589','We evaluated the leaf essential oil in whole or fractions of Dysphania ambrosioides with respect to their resistance to wood decay fungal activities in vitro of 4 fungi. The main ingredients with the greater anti-wood decay capability were also identified. Fresh leaves of D. ambrosioides were hydrodistillated in a Clevenger-type apparatus and the resulting oil characterized using GC-FID and GC-MS instruments. The essential oil was found to consist of α-terpinene (30.5%), p-cymene (17.3%), carvacrol (16.2%), and ascaridole (15.1%). The oil showed resistance to wood decay activity of Trametes versicolor, Phanerochaete chrysosporium, Phaeolus schweinitzii, and Lenzites sulphureu. The oil had excellent resistance to wood decay fungal activities, and the active compounds were shown to be carvacrol and ascaridole.'),(2020,'10.1186/1756-3305-7-407','Linalool, derived from Cinnamomum camphora (L.) Presl leaf extracts, possesses molluscicidal activity against Oncomelania hupensis and inhibits infection of Schistosoma japonicum','Parasites & Vectors',2014,'https://doi.org/10.1186/1756-3305-7-407',65,'https://openalex.org/W2139948225','BACKGROUND: Schistosomiasis japonicum remains a considerable economic and public health concern in China, the Philippines and Indonesia. Currently available measures to control the unique intermediate host Oncomelania hupensis are frequently associated with severe side effects. Previous studies have demonstrated that linalool-rich extracts from various plants exhibited promising biological activities including cytotoxic, anti-microbial and anti-parasitic properties. METHODS: We identified the components of leaf extracts from Cinnamomum camphora by gas chromatography coupled to mass spectrometry (GC-MS) and investigated molluscicidal and larvicidal effects of linalool against O. hupensis and Schistosoma japonicium. The ultrastructural alterations in gills, salivary gland, stomach and hepatopancreas of snails were observed under the light microscope and transmission electron microscope, and lesions to tegument of cercaria were examined under a light microscope and fluorescence microscope. We then evaluated the effects of linalool on skin penetration and migration of schistosomula and adult survival by measurement of worm burden and egg counts in Balb/C mice infected with linalool-treated cercariae. RESULTS: In the present work, 44 components were identified from the leaf extracts of C. camphora, of which linalool was the most abundant constituent. Linalool exhibited the striking molluscicidal and larvicidal effects with LC50 = 0.25 mg/L for O. hupensis and LC50 = 0.07 mg/L for cercaria of S. japonicium. After exposure to linalool, damage to the gills and hepatopancreas of the snails, and to the tegument and body-tail joint of cercariae was apparent. In addition, linalool markedly reduced the recovered schistosomulum from mouse skin after challenge infection, and therefore decreased the worm burden in infected animals, but not fecundity of female adults of the parasite. CONCLUSIONS: Our findings indicated that linalool might be a novel chemotherapeutic agent against S. japonicium and the snail intermediate host.'),(2021,'10.1201/9780203216637-20','Large cardamom (Amomum subulatum Roxb.)','NA',2002,'https://doi.org/10.1201/9780203216637-20',25,'https://openalex.org/W2966026599','Large cardamom (L. cardamom) or Nepal cardamom (Amomum subulatum Roxb.) is a spice cultivated in the sub-Himalayan region of north-eastern India, especially in Sikkim since time immemorial. In the past the aboriginal inhabitants of Sikkim, Lepchas, collected capsules of large cardamom from natural forest, but later on these forests passed into village ownership and the villagers started cultivation of large cardamom. The presence of wild species, locally known as churumpa, and the variability within the cultivated species supports the view of its origin in Sikkim (Subba, 1984). Later the cultivation has spread to northern Uttar Pradesh, north-eastern States of India (Arunachal Pradesh, Mizorum and Manipur), Nepal and Bhutan. Sikkim is the largest producer of large cardamom; the annual production in India is about 3500-4000 mt of cured L. cardamom. The average productivity is 100-150 kg/ha, but in wellmaintained plantations the productivity reaches 1000-2000 kg/ha. Nepal and Bhutan are the other two countries cultivating this crop with an annual production of about 1500 mt. This spice is used in Ayurvedic preparation in India as mentioned by Susruta in the sixth century BC and also known among Greeks and Romans as Amomum (Ridley, 1912). L. cardamom contains ca.1.98-2.67 per cent volatile oil and is mainly used in flavouring food products (Gupta et al., 1984). The seeds also possess certain medicinal properties, as carminative, stomachic, diuretic, cardiac stimulant, antiemetic and are a remedy for throat and respiratory troubles (Singh et al., 1978).'),(2022,'10.1201/9781003245292-7','Avocado (Persea americana Mill)','NA',2021,'https://doi.org/10.1201/9781003245292-7',0,'https://openalex.org/W3202172496','NA'),(2023,'10.1248/bpb.28.1892','Essential Oil Composition, Antibacterial and Antioxidant Activity of the Oil and Various Extracts of Ziziphora clinopodioides subsp. rigida (BOISS.) RECH. f. from Iran','Biological and Pharmaceutical Bulletin',2005,'https://doi.org/10.1248/bpb.28.1892',131,'https://openalex.org/W2048474425','The chemical composition of the essential oil obtained from the aerial parts of Z. clinopodioides subsp. rigida (BOISS.) RECH. f. was analysed by GC and GC-MS. Thirty-one constituents accounting to 99.5% of the total oil were identified. Oxygenated monoterpenes (93.3%) were the predominant portion of the oil with pulegone (45.8%), piperitenone (17.4%), p-menth-3-en-8-ol (12.5%) and thymol (8.0%) as the main constituents. Antibacterial activity of the oil and its two main compounds and various extracts of plant were tested against seven Gram-(+) or Gram-(-) bacteria. It was found that the oil and MeOH extract (M) exhibited interesting antibacterial activity. The samples were also subjected to screening for their possible antioxidant activity by using 2,2-diphenyl-1-picrazylhydrazyl (DPPH) assay. The free radical scavenging activity of MeOH extract (M) was superior to all other extracts (IC50=30.7 microg/ml), while the oil was less effective.'),(2024,'10.1303/aez.2008.599','Chemical composition and insecticidal potential of essential oils from Egyptian plants against Sitophilus oryzae (L.) (Coleoptera: Curculionidae) and Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae)','Applied Entomology and Zoology',2008,'https://doi.org/10.1303/aez.2008.599',103,'https://openalex.org/W1977271278','Essential oils of eight plants growing in Egypt were isolated by hydrodistillation. The chemical composition of the isolated oils was examined by gas chromatography/mass spectrometry (GC-MS). In the contact toxicity assay, the oils of Mentha microphylla and Artemisia judaica were the most potent against Sitophilus oryzae. When tested against Tribolium castaneum, the oils of M. microphylla, Eucalyptus camaldulensis and A. judaica showed the highest activity among the test oils with M. microphylla being the most potent. In the fumigant assay, the oil of M. microphylla displayed the strongest insecticidal activity against S. oryzae (LC50=0.21 μl/L), while the oils of Lantana camara (LC50=29.47 μl/L) and E. camaldulensis (LC50=30.81 μl/L) revealed good activity. In the case of T. castaneum, the oil of M. microphylla (LC50=4.51 μl/L) was the most effective, followed by Citrus reticulata (LC50=19.47 μl/L) and Schinus terebenthifolius (LC50=20.50 μl/L). The most interesting finding in this study is the potent contact and fumigant toxicity of M. microphylla oil against S. oryzae and T. castaneum. These results suggested that M. microphylla oil could be used as a potential control agent for S. oryzae and T. castaneum.'),(2025,'10.13040/IJPSR.0975-8232.9(5).2005-10','NA','International Journal of Pharmaceutical Sciences and Research',2018,'https://doi.org/10.13040/ijpsr.0975-8232.9(5).2005-10',14,'https://openalex.org/W4247104684','Bioactive compounds are the frontline potent agents in both nutraceutical and pharmaceutical industries.Recently, the bioactive compounds are gaining much importance for their ability in enhancing resistance to various diseases and to improve the health of people both by traditional and modern ways of administrations.Therefore, in the present investigation was undertaken to identify the compounds present in the leaf of Waltheria indica Linn.by Gas Chromatography-Mass Spectrometry (GC-MS) analysis by ethanol extract.The GC-MS analysis showed 27 bioactive compounds.The major compounds identified are 2,3-Dihydro-3,5-Dihydroxy-6-methyl-4h-pyran-4-one, tetradecane, nonadecane, tetracosane, phytol and squalene.In a mass spectrum, each compounds were identified based on their retention time and peak area.Pharmacological activities of these compounds indicated that the compounds present in the leaf of said plant can be used as a crude drug and can also be used to develop a novel drug.'),(2026,'10.1371/journal. pone.0205997','NA','NA',0,'NA',0,'NA','NA'),(2027,'10.1371/journal.pone.0060269','Antioxidant and Antibacterial Activities of Crude Extracts and Essential Oils of Syzygium cumini Leaves','PLoS ONE',2013,'https://doi.org/10.1371/journal.pone.0060269',168,'https://openalex.org/W2158011080','This research highlights the chemical composition, antioxidant and antibacterial activities of essential oils and various crude extracts (using methanol and methylene chloride) from Syzygium cumini leaves. Essential oils were analyzed by gas chromatography-mass spectrometry (GC-MS).The abundant constituents of the oils were: α-pinene (32.32%), β-pinene (12.44%), trans-caryophyllene (11.19%), 1, 3, 6-octatriene (8.41%), delta-3-carene (5.55%), α-caryophyllene (4.36%), and α-limonene (3.42%).The antioxidant activities of all extracts were examined using two complementary methods, namely diphenylpicrylhydrazyl (DPPH) and ferric reducing power (FRAP). In both methods, the methanol extract exhibited a higher activity than methylene chloride and essential oil extracts. A higher content of both total phenolics and flavonoids were found in the methanolic extract compared with other extracts. Furthermore, the methanol extract had higher antibacterial activity compared to methylene chloride and the essential oil extracts. Due to their antioxidant and antibacterial properties, the leaf extracts from S. cumini may be used as natural preservative ingredients in food and/or pharmaceutical industries.'),(2028,'10.1371/journal.pone.0176126','Oils extracted from Eupatorium adenophorum leaves show potential to control Phythium myriotylum in commercially-grown ginger','PLoS ONE',2017,'https://doi.org/10.1371/journal.pone.0176126',16,'https://openalex.org/W2611762426','Oils extracted from the leaves of Eupatorium adenophorum were tested in vitro and in vivo against the soilborne pathogen Pythium myriotylum which causes soft rot, a devastating disease of commercial ginger production in China. Twelve compounds accounting for 99.15% of the total oil composition were identified by GC-MS. The major components were 10Hβ-9-oxo-agerophorone (37.03%), 10Hα-9-oxo-agerophorone (37.73%) and 9-oxo-10, 11-dehydro-agerophorone (23.41%). Antifungal activity was tested by the poisoned food technique against P. myriotylum, indicating minimum inhibitory concentrations of 100μg/ml after 7 days incubation. In addition, the oil extracts greatly inhibited the formation of both wet and dry mycelial biomass. The combination of E. adenophorum oil extracts and synthetic fungicides showed a strong synergistic effect, inhibiting the mycelial growth in in vitro assays. The synergistic effect of oil extracts with fungicides could allow fungicides to be used at reduced rates in the future which has environmental advantages. Oil extracts applied at 160 and 200μg/ml concentrations to ginger rhizomes before inoculation with P. myriotylum significantly reduced the infection rate in ginger. Examination by light and transmission electron microscopy revealed that oil extracts caused swelling of the hyphae, disruption of the cell wall, degradation of the cytoplasmic organelles and shortening of the cytoplasmic inclusion. These results suggested that the plasma membrane and endomembrane systems of P. myriotylum were severely damaged by the oil extracts of E. adenophorum which offer significant potential for use as a fungicide to control P. myriotylum.'),(2029,'10.14233/ajchem.2013.14659','Study on Volatile Components of Butterfly Nectar Plants and Host Plants','Asian Journal of Chemistry',2013,'http://doi.org/10.14233/ajchem.2013.14659',4,'https://openalex.org/W2333043298','Volatile components of butterfly nectar plants, Lantana camara L., Vitex trifolia L. and Hibiscus rosa-sinensis L. and host plants, Cleome spinosa L., Dregea volubilis (Linn.f.) Benth.ex Hook.f. and Parsonsia laevigata (Moon) Alston, were analyzed by automatic thermal desorption-gas chromatography-mass spectrometry process (ATD-GC-MS).Of the three nectar plants, the most dominant components were terpenes, which total content exceeded 60 %, together with eucalyptol with higher content.Also there were some hydrocarbons, alcohols and aromatic compounds detected in the three nectar plants.Host plant volatiles presented a different composition.C. Spinosa volatiles were mainly composed of terpenoids (36.35 %), aldehydes (29.07 %), ethers (10.48 %) and acids (9.15 %).D. volubilis volatile compounds were mainly esters (21.03 %), next were terpenoids (19.53 %).P. laevigata volatiles were composed mainly of aldehydes (32.2 %) and esters (19.41 %).'),(2030,'10.14393/BJ-v35n5a2019-41999','Schinus terebinthifolius essential oil and fractions in the control of Aedes aegypti','Bioscience Journal',2019,'https://doi.org/10.14393/bj-v35n5a2019-41999',28,'https://openalex.org/W2980920262','Several technologies have been developed to control Aedes aegypti, mainly studies on isolated plant molecules. The Schinus terebinthifolius (Raddi) (Anacardiaceae), popularly known as pink pepper is a plant widely used in reforestation of degraded areas and its fruits are used as condiments. The objective of this work was to investigate the potential of essential oils (EOs) and fractions (FRs) obtained from fresh fruits and leaves of S. terebinthifolius. The EOs were obtained by hydrodistillation (2 hours), fractionated on a chromatographic column using as the stationary phase silica gel 60 (0.063-0.2mm), mobile phases: n-hexane, dichloromethane, ethyl acetate and methanol and chemically evaluated by gas chromatography coupled to mass spectrometer (GC/MS). EOs and FRs were tested against larvae of the third stage and pupae of Ae. aegypti by Immersion Test at concentrations ranging from 500.00 to 0.003 mg mL-1 (v/v). The hexane FRs obtained from fruits and leaves were the ones that showed the greatest activity on the larvae (LC99.9= 0.60 mg mL-1 and LC99.9 0.64 mg mL-1, respectively) and pupae (LC99,9 = 2.51 mg mL-1 and 2.61 mg mL-1, respectively). These results were confirmed by the anticholinesterase activity where the hexane (fruit and leaf) FRs presented the highest inhibitory potential on the acetylcholinesterase enzyme (0.156 mg mL-1 and 0.312 mg mL-1, respectively), suggesting the likely mechanism of action. The larvicidal potential can be explained by the presence of the major compounds bicyclogermacrene and germacrene D in the hexane FRs, indicating in this way that they may replace or even act in synergisms with conventional chemical larvicides. In this way the present study opens the field for new researches, aiming the development of products with the compounds bicyclogermacrene and germacrene D, as an alternative in the control of this culicide.'),(2031,'10.15376/biores.16.4.7767-7783','Potential insecticidal activity of four essential oils against the rice weevil, Sitophilus oryzae (L.) (Coleoptera: Curculionidae)','BioResources',2021,'https://doi.org/10.15376/biores.16.4.7767-7783',15,'https://openalex.org/W3201884131','Oils extracted from Cymbopogon citratus, Lantana camara, Artemisia camphorata, and Imperata cylindrica plants were used as potential insecticides against the rice weevil, Sitophilus oryzae (L.) (Coleoptera: Curculionidae). The phytochemical composition of the isolated oils was identified by gas chromatograph-mass spectrometry (GC-MS). Oil contact toxicities were evaluated against the adults of S. oryzae. The activities of acetylcholinesterase (AChE), alkaline phosphatase (ALP), and transaminases enzymes (AST) were measured. L. camara oil (LC50 = 9.81 mg/cm2) demonstrated the highest effect, followed by C. citratus oil (LC50 = 10.89 mg/cm2), A. camphorata EO (LC50 = 16.12 mg/cm2), and I. cylindrica oil (LC50= 36.85 mg/cm2) against the adults of S. oryzae. The inhibition percentages of AChE were 38.8, 41.7, 35.0, and 27.2%; ALP were 42.4, 49.3, 28.1, and 18.7%; AST were 33.9, 38.7, 20.8, and 11.8%; and ALT were 22.7, 30.5, 14.6, and 9.6% after treated S. oryzae with oils from C. citratus, L. camara, A. camphorata and I. cylindrica, respectively. The highest abundant compounds in C. citratus were geranial (25.95%), nerylacetal (8.85%), and neral (8.45%), in L. camara were caryophyllene (12.2%), and 3-elemene (8.89%), in A. camphorata were germacrene D-4-ol (20.83%), and borneol (19.47%), and in I. cylindrica were 5-phenylundecane (10.68%), and 6-phenyldodecane (8.70%).'),(2032,'10.15835/nbha49112233','Antioxidant and cytotoxic activities of Artemisia monosperma L. and Tamarix aphylla L. essential oils','Notulae Botanicae Horti Agrobotanici Cluj-Napoca',2021,'https://doi.org/10.15835/nbha49112233',28,'https://openalex.org/W3149141158','Essential (volatile) oil from leaves of Artemisia monosperma L. belonging to family Asteraceae, and aerial parts of Tamarix aphylla L. (Athel) belonging to family Tamaricaceae were collected from the desert of Ha\'il region, northern region of Saudi Arabia, hydro distilled by Clevenger apparatus and analysed by means of GC-MS techniques. Antioxidant activities of essential oils of A. monosperma and T. aphylla compared with ascorbic acid and butylated hydroxytoluene (BHT) as reference antioxidant compound were determined by method of DPPH radical scavenging assay and ABTS assay. In vitro screening of potential cytotoxicity of essential oils was also evaluated against human promyelocytic leukaemia cell lines (HL60 and NB4). The GC/MS analysis of A. monosperma essential oil resulted in identification of 61 components predominated mainly by β-Pinene as principal component (29.87%) and T. aphylla resulted in identification of 37 components of essential oil predominated mainly by 6,10,14- trimethyl-2-pentadecanone (21.43%) as principal component. Antioxidant activity as 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and 2,2 -azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS) increased with increasing essential oil concentrations of A. monosperma and T. aphylla (25, 50, 75, 100 and 200 μg mL-1). The most pronounced increases detected in the high concentrations of the two essential oils. Biologically, essential oil extracts exhibited cytotoxicity effects in dose dependent manner against human promyelocytic leukaemia cell lines (HL60 and NB4). In conclusion, A. monosperma and T. aphylla essential oils could be valuable source for cytotoxic agents with high safety and selective cytotoxicity profiles.'),(2033,'10.1590/0001-3765201391011','Chemical study and larvicidal activity against Aedes aegypti of essential oil of Piper aduncum L. (Piperaceae)','Anais da Academia Brasileira de Ciências',2013,'https://doi.org/10.1590/0001-3765201391011',65,'https://openalex.org/W2041700253','Piper aduncum L. is used in folk medicine to treat respiratory and inflammatory diseases. The aim of this study was to analyze the essential oil from leaves of P. aduncum collected in the Brazilian Cerrado, North of Minas Gerais, as well as to evaluate the larvicidal activity of this oil and of its major constituent. The essential oil was analyzed by gas chromatography coupled to flame ionization detector and gas chromatography coupled to mass spectrometry that allowed characterizing 23 compounds (monoterpenes: 90.4%; sesquiterpenes: 7.0%). The major component was 1,8-cineole (53.9%). This oil showed to be very different from those obtained from the same species. Larvae of A. aegypti were exposed to different concentrations of the essential oil and 1,8-cineole. The mortality rate of 100% was obtained after 24 h of treatment with the oil at concentrations of 500 and 1,000 ppm. After 48 h of treatment, the mortality rate was 80% and 50% for concentrations of 250 and 100 ppm, respectively. The LCââ obtained after 24h was estimated in 289.9 ppm and after 48 h was 134.1 ppm. The major compound 1,8-cineole showed no larvicidal activity.'),(2034,'10.1590/0074-02760160361','Linalool, a Piper aduncum essential oil component, has selective activity against Trypanosoma cruzi trypomastigote forms at 4°C','Memórias do Instituto Oswaldo Cruz',2017,'https://doi.org/10.1590/0074-02760160361',50,'https://openalex.org/W2585728632','BACKGROUND: Recent studies showed that essential oils from different pepper species (Piper spp.) have promising leishmanicidal and trypanocidal activities. OBJECTIVES: In search for natural compounds against Trypanosoma cruzi, different forms of the parasite were incubated for 24 h at 28ºC or 4ºC with Piper aduncum essential oil (PaEO) or its main constituents linalool and nerolidol. METHODS: PaEO chemical composition was obtained by GC-MS. Drug activity assays were based on cell counting, MTT data or infection index values. The effect of PaEO on the T. cruzi cell cycle and mitochondrial membrane potential was evaluated by flow cytometry. FINDINGS: PaEO was effective against cell-derived (IC50/24 h: 2.8 μg/mL) and metacyclic (IC50/24 h: 12.1 μg/mL) trypomastigotes, as well as intracellular amastigotes (IC50/24 h: 9 μg/mL). At 4ºC - the temperature of red blood cells (RBCs) storage in blood banks - cell-derived trypomastigotes were more sensitive to PaEO (IC50/24 h = 3.8 μg/mL) than to gentian violet (IC50/24 h = 24.7 mg/mL). Cytotoxicity assays using Vero cells (37ºC) and RBCs (4ºC) showed that PaEO has increased selectivity for cell-derived trypomastigotes. Flow cytometry analysis showed that PaEO does not affect the cell cycle of T. cruzi epimastigotes, but decreases their mitochondrial membrane potential. GC-MS data identified nerolidol and linalool as major components of PaEO, and linalool had trypanocidal effect (IC50/24 h: 306 ng/mL) at 4ºC. MAIN CONCLUSION: The trypanocidal effect of PaEO is likely due to the presence of linalool, which may represent an interesting candidate for use in the treatment of potentially contaminated RBCs bags at low temperature.'),(2035,'10.1590/1519-6984.189089','Antibacterial and antiproliferative activities of the fresh leaf essential oil of Psidium guajava L. (Myrtaceae)','Brazilian Journal of Biology',2018,'https://doi.org/10.1590/1519-6984.189089',63,'https://openalex.org/W2900596758','This study evaluated the antibacterial and antiproliferative activities of the essential oil of Psidium guajava leaves (PG-EO), traditionally used in folk medicine. The essential oil was obtained from fresh leaves by hydrodistillation, using a modified Clevenger apparatus. The major PG-EO chemical constituents were identified by GC-MS and GC-FID as being β-caryophyllene (16.1%), α-humulene (11.9%), aromadendrene oxide (14.7%), δ-selinene (13.6%), and selin-11-en-4α-ol (12.5%). The antibacterial activity of the essential oil of P. guajava leaves was determined in terms of its minimum inhibitory concentrations (MIC) using the broth microdilution method in 96-well microplates. PG-EO had moderate activity against Streptococcus mutans (MIC = 200 µg/mL), S. mitis (MIC = 200 µg/mL), S. sanguinis (MIC = 400 µg/mL), S. sobrinus (MIC = 100 µg/mL), and S. salivarius (MIC = 200 µg/mL). The antiproliferative activity was evaluated against different tumor cell lines: breast adenocarcinoma (MCF-7), human cervical adenocarcinoma (HeLa), and human gliobastoma (M059J). A normal human cell line (GM07492A, lung fibroblasts) was included. The antiproliferative activity was evaluated using the XTT assay and the results were expressed as IC50. The essential oil showed significantly lower IC50 values against MCF-7 and M059J lines than that obtained for the normal line, showing selectivity. Our results suggest that the essential oil of Psidium guajava L. has promising biological activities and can be considered a new source of bioactive compounds.'),(2036,'10.1590/1809-4392202002691','Ecological risk assessment of Piper aduncum essential oil in non-target organisms','Acta Amazonica',2021,'https://doi.org/10.1590/1809-4392202002691',20,'https://openalex.org/W3134921225','ABSTRACT One possible alternative to chemotherapeutic agents in the treatment and prevention of diseases in fish farms is the use of Piper aduncum essential oil. However, ecotoxicological data are required to ensure its proper use and to prevent adverse effects on non-target organisms. These data are relevant since this essential oil is described as having insecticidal, molluscicidal and cytotoxic activitiy that may be associated with its chemical composition. Thus, the aim of this study was to evaluate the ecotoxicity of P. aduncum essential oil to five test organisms using the species sensitivity distribution (SSD) statistical approach. The chemical composition of the essential oil was characterized by means of gas chromatography coupled to mass spectrometry (GC-MS) and gas chromatography-flame ionization detection (GC-FID) for identification and quantitation purposes, respectively. The main component (75.5%) of the essential oil was dillapiole. The hazardous concentration for 5% of biological species (HC5) was calculated to determine the 95% protection level, resulting in a value of 0.47 mg L-1 (with a confidence interval of 0.028 - 1.19 mg L-1. ). A concentration range related to the level of protection for aquatic communities (the predicted no-effect concentration, PNEC) was determined through the application of safety factors to the HC5 value. The ecotoxicity parameters showed that P. aduncum essential oil can be used safely in water bodies at a concentration equal to or below 0.09 mg L-1.'),(2037,'10.1590/S0100-40422006000300012','Composition and antifungal activity of essential oils from Piper aduncum, Piper arboreum and Piper tuberculatum','Química Nova',2006,'https://doi.org/10.1590/s0100-40422006000300012',132,'https://openalex.org/W2147162592','The composition of essential oils from leaves, stems and fruits of Piper aduncum, P. arboreum and P. tuberculatum was examined by means of GC-MS and antifungal assay. There was a predominance of monoterpenes in P. aduncum and P. tuberculatum and of sesquiterpenes in P. arboreum. P. aduncum showed the richest essential oil composition, including linalool. The essential oils from fruits of P. aduncum and P. tuberculatum showed the highest antifungal activity with the MIC of 10 µg as determined against Cladosporium cladosporioides and C. sphaerospermum, respectively. This is the first report of the composition of essential oils from P. tuberculatum.'),(2038,'10.1590/S0102-695X2012005000057','Essential oil from leaves of Lantana camara: a potential source of medicine against leishmaniasis','Revista Brasileira de Farmacognosia',2012,'https://doi.org/10.1590/s0102-695x2012005000057',34,'https://openalex.org/W1620961751','NA'),(2039,'10.1590/S0102-695X2012005000098','Chemical constituents and evaluation of cytotoxic and antifungal activity of Lantana camara essential oils','Revista Brasileira de Farmacognosia',2012,'https://doi.org/10.1590/s0102-695x2012005000098',35,'https://openalex.org/W1926573924','The essential oil (EO) of aerial parts of Lantana camara L., Verbenaceae, from Simões, Piaui, Northeast of Brazil, were obtained by hydrodistillation and analyzed by GC-FID and GC-MS techniques. In total, 68 compounds were identified. The most representative compounds of the oil were mono and sesquiterpenes. The main compounds found in the oil of the leaves in different months were β-caryophyllene (10.5%, in June of 2009), sabinene (7.98%, in September of 2008), limonene (7.68%, in September of 2008), spathulenol (11.64%, in September of 2008). The oil from stems of L. camara was characterized by a largest amount of sesquiterpenoids, with spatulenol (15.9%) and caryophyllene oxide (17.1% in June of 2009), as main components. β-Gurjunene (32.7%, in September of 2008) was the most prominent compound in the stems oils, which was absent or at very low relative abundance in leaves. L. camara essential oils from leaves were cytotoxic to V79 mammalian cells and also to Artemia salina, showing 50% lethal concentration (LC50) values from 0.23 µg/mL. The in vitro data obtained in this study suggested that EO may also be effective treating yeast infection in patients infected with fluconazole and terbinafine resistant isolates, but its toxicity must be monitored carefully.'),(2040,'10.1590/S1413-70542011000100008','Evaluation of antifungal activity of Pittosporum undulatum L. essential oil against Aspergillus flavus and aflatoxin production','Ciência e Agrotecnologia',2011,'https://doi.org/10.1590/s1413-70542011000100008',22,'https://openalex.org/W2022273459','The presence of mycotoxins as a result of fungal attack can occur before, after and during the harvest and storage operations on agricultural crops and food commodities. Considering the inhibitory property of essential plant oils on the mycelial development of fungi and the importance of Aspergillus flavus, the main producer of aflatoxins, this research was designed to evaluate the toxicity of essential oil from Pittosporum undulatum against A. flavus. The essential oils were obtained from P. undulatum leaves, collected in different months and analyzed by GC/MS. The oils were rich in hydrocarbon, monoterpenes and sesquiterpenes and it was observed a significant variation on the chemical composition of the essential oil of leaves at different months. Besides, the essential oils were tested against fungal growth and the results showed different spectrum of inhibition on A. flavus. However, the essential oils inhibited the aflatoxin B1 production.'),(2041,'10.1590/S1517-838220100001000023','Antibacterial activity, chemical composition, and cytotoxicity of leaf\'s essential oil from brazilian pepper tree (schinus terebinthifolius, raddi).','PubMed',2010,'https://pubmed.ncbi.nlm.nih.gov/24031476',42,'https://openalex.org/W2169996545','The antibacterial potential of leaf\'s essential oil (EO) from Brazilian pepper tree (Schinus terebinthifolius Raddi) against staphylococcal isolates from dogs with otitis externa was evaluated. The minimum inhibitory concentration of EO ranged from 78.1 to 1,250 μg/mL. The oil was analyzed by GC and GC/MS and cytotoxicity tests were carried out with laboratory animals.'),(2042,'10.1590/s0102-695x2006000100007','Influence of the harvesting time, temperature and drying period on basil (Ocimum basilicum L.) essential oil','Revista Brasileira de Farmacognosia',2006,'https://doi.org/10.1590/s0102-695x2006000100007',145,'https://openalex.org/W1915388887','Ocimum basilicum L. essential oil with high concentration of linalool is valuable in international business. O. basilicum essential oil is widely used as seasoning and in cosmetic industry. To assure proper essential oil yield and quality, it is crucial to determine which environmental and processing factors are affecting its composition. The goal of our work is to evaluate the effects of harvesting time, temperature, and drying period on the yield and chemical composition of O. basilicum essential oil. Harvestings were performed 40 and 93 days after seedling transplantation. Harvesting performed at 8:00 h and 12:00 h provided higher essential oil yield. After five days drying, the concentration of linalool raised from 45.18% to 86.80%. O. basilicum should be harvested during morning and the biomass dried at 40ºC for five days to obtain linalool rich essential oil.');
