Abstract The leaf oil of Flourensia cernua DC. collected from the Jomada Experimental Range in southcentral New Mexico was analyzed. GC/MS and retention indices were used to identify 89 components. β-Eudesmol (24.5%), α-eudesmol (6.9%), limonene (6.6%), γ-eudesmol (4.6%), myrcene (3.8%), borneol (3.3%), and δ-3-carene (3.0%) were the major components of the steam distilled oil. In an ethanol extract of intact leaves, flourensadiol (44.6%), artemisia alcohol (5.5%), viridiflorol (2.7%), and borneol (2.0%) were the main components.