Abstract The composition of the essential oil from whole aerial parts, flowers, leaves and stems of Senecio royleanus collected from sub-alpine region of central Himalaya, India, has been analyzed by GC, GC/MS, NMR spectroscopy and X-Ray diffraction. A total of fifty components were identified representing 95.0â97.3% of the oil. 1,10 b-Epoxy-6-oxofuranoeremophelane constituted the major component (39.4â69.2%) of the oil.