The chemical profile of the essential oil obtained from leaves and inflorescences of Psidium myrsinites DC. (Myrtaceae) growing wildly in the Brazilian Cerrado was analyzed by GC/FID and CG/MS. The essential oil had a slimy and translucent appearance. The oil yield was 0.1% and the main components were oxygenated sesquiterpenes (68.2%) and non-oxygenated sesquiterpenes (18.3%). Caryophyllene oxide (26.1%), humulene epoxide II (8.8%), Î²-caryophyllene (7.4%) and Î±-caryophyllene (5.4%) were the major compounds. It is worth to notice that the most abundant substances have very close structures. The oil yield and composition was very similar to other species belonging to the same genus.