Leaf oil of male Baccharis punctulata DC. from Argentina was analyzed at vegetative and at flowering stage. Compound identification and differences are reported. The major component at vegetative stage (42-48%) was identified as the rare furanocadinane verboccidentafuran. 13C-NMR data of verboccidentafuran are assigned for the first time. Other components are δ-elemene (9.1%), β-elemene (3.1%), amorpha-4,7(11)-diene (7.5%), β-bisabolene (2.4%), δ-cadinene (2.5%), cis-cadin-4-en-7α-ol (5.0%), α-muurolol (2.8%), α-cadinol (2.0%) and α-bisabolol (2.7%). At flowering stage, oils showed two major components: verboccidentafuran (22.4%) and the infrequent germacra-1(10),5-dien-4α-ol (17.3%) which was unambiguously differentiated from the 4β-ol diastereoisomer. Other components are (E)-β-ocimene (2.4%), linalool (2.5%), δ-elemene (8.6%), β-elemene (3.3%), amorpha-4,7(11)-diene (2.3%), elemol (2.6%), guaiol (2.4%), cis-cadin-4-en-7α-ol (6.4%), α-muurolol (3.4%) and α-bisabolol (2.3%). Female plant leaf oils showed similar tendency. All oils were sesquiterpene-rich. Different composition is associated with flowering. Major compounds are reported in B. punctulata for the first time.