Abstract The oils from leaves and inflorescences of Sideritis syriaca L. grown and harvested in Italy were analyzed by GC/MS. The major components in the oil from leaves contained hexadecanoic acid (31.1%), epi-α-bisabolol (14.5%), benzyl benzoate (7.5%), and (E)-caryophyllene (6.4%), while in the oil from the inflorescences contained epi-α-bisabolol (25.7%), benzyl benzoate (17.7%), hexadecanoic acid (7.8%), β-caryophyllene (7.3%), and (Z)-α-bisabolene (6.0%).