Abstract The chemical composition of the essential oil obtained from the leaves of Eugenia melanadenia Krug et Urb. from Cuba was examined by combined GC/MS. The oil was characterized by the presence of 1,8-cineole (45.3%), terpinen-4-ol (10.6%), p-cymene (8.2%), Î²-eudesmol (7.0%) and Î±-terpineol (6.7%) as major constituents.