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Title phytochemical profile and biological effects of essential oils from three inula species grown in tunisia
Journal journal of essential oil research
Year 2022
DOI 10.1080/10412905.2022.2075479
Cited By 7
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Abstract
this work investigated the chemical composition of essential oils (eos) obtained from the aerial parts of three inula species of the tunisian flora as well as their biological properties. inula viscosa essential oil (iveo) contained mainly -costic acid (65.4%). the eos of inula graveolens (igeo) and inula crithmoides (iceo) were characterized by high contents of p-cymene derivatives while iceo stands out by high levels of modheph-2-ene (16.5%) and tiglic esters (14.1%). moreover, a notable antioxidant power was proved by the orac test for the three eos. finally, the cytotoxic activity was evaluated on two healthy cell lines (ccd45-sk, huvecs) and two cancer cell lines (hepg-2, mcf-7) and it appeared that the eos were particularly effective on mcf-7 human breast cancer cells with lc50 equal to 79, 16, and 63 ug. ml-1 for iveo, igeo, and iceo, respectively.
3
Plants
68
Compounds
115
Records

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Compounds
Plants
Plant Parts
All Records
CompoundCount
tricosane3
bornyl acetate3
borneol3
caryophyllene oxide3
heptacosane3
hexadecanoic acid3
beta-selinene3
modheph-2-ene3
pentacosane3
phytone3
tetradecanoic acid3
caryophylla-4(12), 8(13)-dien-5-alpha-ol2
8,9-dehydro-2,5-dimethoxy-para-cymene2
8,9-dehydrothymol2
8,9-dehydrothymol methyl ether2
8,9-dehydrothymyl isobutyrate2
alpha-costic acid2
2,5-dimethoxy-para-cymene2
alpha-costal2
beta-costol2
hexacosane2
para-cymen-8-ol2
selin-11-en-4-alpha-ol2
phytol2
para-mentha-1(7),2-dien-8-ol2
carvacrol2
(e)-beta-damascenone2
thymyl isobutyrate2
methyl linoleate2
thymyl 2-methylbutyrate2
methylhexadecanoate2
thymol methyl ether2
o-xylene2
para-cymene2
para-xylene2
t-cadinol2
(e)-nerolidol1
nonanoic acid1
alpha-costol1
dodecanoic acid1
decanoic acid1
eugenol1
gamma-costic acid1
camphor1
beta-costic acid1
selin-6-en-4-alpha-ol1
14-hydroxy-9-epi-(e)-caryophyllene1
10-isobutyryloxy-8,9-epoxythymyl isobutyrate1
10-(2-methylbutyryloxy)-8,9-epoxythymyl isobutyrate1
abienol1
thymyl tiglate1
thymol1
silphin-1-ene1
para-cymen-7-yl tiglate1
modhephan-3-one1
humulene epoxide ii1
carvacryl tiglate1
beta-isocomene1
alpha-isocomene1
10-acetoxy-8,9-dehydrothymyl tiglate1
8,9-epoxythymyl isobutyrate1
8,9-dehydrothymyl tiglate1
8,9-dehydrothymyl 2-methylbutyrate1
6-methoxy-10-acetoxy-8,9-epoxythymyl tiglate1
4-hydroxy-2-methylacetophenone1
10-acetoxythymyl tiglate1
10-acetoxy-8,9-epoxythymyl tiglate1
10-acetoxy-8,9-epoxythymyl 2-methylbutyrate1
PlantFamily
Inula crithmoidesasteraceae
Inula graveolensasteraceae
Inula viscosaasteraceae
Plant PartCount
aerial parts115
PlantCompoundPart%
Inula crithmoides 10-acetoxy-8,9-dehydrothymyl tiglate aerial parts 2.5
Inula crithmoides 10-acetoxy-8,9-epoxythymyl 2-methylbutyrate aerial parts 2.2
Inula crithmoides 10-acetoxy-8,9-epoxythymyl tiglate aerial parts 1
Inula crithmoides 10-acetoxythymyl tiglate aerial parts 1.4
Inula crithmoides 2,5-dimethoxy-para-cymene aerial parts 0.6
Inula crithmoides 4-hydroxy-2-methylacetophenone aerial parts 0.7
Inula crithmoides 6-methoxy-10-acetoxy-8,9-epoxythymyl tiglate aerial parts 1.4
Inula crithmoides 8,9-dehydro-2,5-dimethoxy-para-cymene aerial parts 3.3
Inula crithmoides 8,9-dehydrothymol aerial parts 1.9
Inula crithmoides 8,9-dehydrothymol methyl ether aerial parts 8.3
Inula crithmoides 8,9-dehydrothymyl 2-methylbutyrate aerial parts 0.9
Inula crithmoides 8,9-dehydrothymyl isobutyrate aerial parts 0.2
Inula crithmoides 8,9-dehydrothymyl tiglate aerial parts 1.2
Inula crithmoides 8,9-epoxythymyl isobutyrate aerial parts 1.4
Inula crithmoides abienol aerial parts 7.5
Inula crithmoides alpha-isocomene aerial parts 1.6
Inula crithmoides beta-costol aerial parts 0.1
Inula crithmoides beta-isocomene aerial parts 2
Inula crithmoides beta-selinene aerial parts 5.5
Inula crithmoides borneol aerial parts 0.05
Inula crithmoides bornyl acetate aerial parts 0.8
Inula crithmoides carvacrol aerial parts 3
Inula crithmoides carvacryl tiglate aerial parts 1.4
Inula crithmoides caryophyllene oxide aerial parts 0.1
Inula crithmoides heptacosane aerial parts 0.2
Inula crithmoides hexadecanoic acid aerial parts 0.9
Inula crithmoides humulene epoxide ii aerial parts 1.4
Inula crithmoides methyl linoleate aerial parts 0.8
Inula crithmoides methylhexadecanoate aerial parts 0.1
Inula crithmoides modheph-2-ene aerial parts 16.5
Inula crithmoides modhephan-3-one aerial parts 1.6
Inula crithmoides o-xylene aerial parts 0.2
Inula crithmoides para-cymen-7-yl tiglate aerial parts 1.2
Inula crithmoides para-cymene aerial parts 1.8
Inula crithmoides para-xylene aerial parts 0.1
Inula crithmoides pentacosane aerial parts 0.5
Inula crithmoides phytone aerial parts 1
Inula crithmoides silphin-1-ene aerial parts 1.5
Inula crithmoides t-cadinol aerial parts 3.6
Inula crithmoides tetradecanoic acid aerial parts 0.1
Inula crithmoides thymol aerial parts 0.1
Inula crithmoides thymol methyl ether aerial parts 1.2
Inula crithmoides thymyl 2-methylbutyrate aerial parts 1.7
Inula crithmoides thymyl isobutyrate aerial parts 0.6
Inula crithmoides thymyl tiglate aerial parts 4
Inula crithmoides tricosane aerial parts 0.1
Inula graveolens (e)-beta-damascenone aerial parts 0.05
Inula graveolens 10-(2-methylbutyryloxy)-8,9-epoxythymyl isobutyrate aerial parts 1.3
Inula graveolens 10-isobutyryloxy-8,9-epoxythymyl isobutyrate aerial parts 4.7
Inula graveolens 14-hydroxy-9-epi-(e)-caryophyllene aerial parts 2.6
Inula graveolens 2,5-dimethoxy-para-cymene aerial parts 0.4
Inula graveolens 8,9-dehydro-2,5-dimethoxy-para-cymene aerial parts 0.2
Inula graveolens 8,9-dehydrothymol aerial parts 0.05
Inula graveolens 8,9-dehydrothymol methyl ether aerial parts 2
Inula graveolens 8,9-dehydrothymyl isobutyrate aerial parts 0.2
Inula graveolens alpha-costal aerial parts 0.5
Inula graveolens alpha-costic acid aerial parts 4.9
Inula graveolens beta-costic acid aerial parts 9.5
Inula graveolens beta-costol aerial parts 0.6
Inula graveolens beta-selinene aerial parts 0.6
Inula graveolens borneol aerial parts 8.1
Inula graveolens bornyl acetate aerial parts 3.4
Inula graveolens camphor aerial parts 0.4
Inula graveolens carvacrol aerial parts 0.05
Inula graveolens caryophylla-4(12), 8(13)-dien-5-alpha-ol aerial parts 7.1
Inula graveolens caryophyllene oxide aerial parts 4.8
Inula graveolens decanoic acid aerial parts 0.8
Inula graveolens dodecanoic acid aerial parts 1.3
Inula graveolens heptacosane aerial parts 0.7
Inula graveolens hexacosane aerial parts 0.3
Inula graveolens hexadecanoic acid aerial parts 0.6
Inula graveolens modheph-2-ene aerial parts 0.6
Inula graveolens nonanoic acid aerial parts 0.8
Inula graveolens para-cymen-8-ol aerial parts 2.2
Inula graveolens para-cymene aerial parts 0.05
Inula graveolens para-mentha-1(7),2-dien-8-ol aerial parts 4.6
Inula graveolens pentacosane aerial parts 1.6
Inula graveolens phytol aerial parts 1.5
Inula graveolens phytone aerial parts 4.8
Inula graveolens selin-11-en-4-alpha-ol aerial parts 3.4
Inula graveolens t-cadinol aerial parts 3.6
Inula graveolens tetradecanoic acid aerial parts 11.7
Inula graveolens thymol methyl ether aerial parts 0.3
Inula graveolens thymyl 2-methylbutyrate aerial parts 0.3
Inula graveolens thymyl isobutyrate aerial parts 1.8
Inula graveolens tricosane aerial parts 0.3
Inula viscosa (e)-beta-damascenone aerial parts 0.5
Inula viscosa (e)-nerolidol aerial parts 1.2
Inula viscosa alpha-costal aerial parts 0.2
Inula viscosa alpha-costic acid aerial parts 65.4
Inula viscosa alpha-costol aerial parts 0.5
Inula viscosa beta-selinene aerial parts 0.3
Inula viscosa borneol aerial parts 0.05
Inula viscosa bornyl acetate aerial parts 0.2
Inula viscosa caryophylla-4(12), 8(13)-dien-5-alpha-ol aerial parts 0.6
Inula viscosa caryophyllene oxide aerial parts 1.8
Inula viscosa eugenol aerial parts 0.7
Inula viscosa gamma-costic acid aerial parts 0.7
Inula viscosa heptacosane aerial parts 0.5
Inula viscosa hexacosane aerial parts 0.4
Inula viscosa hexadecanoic acid aerial parts 0.3
Inula viscosa methyl linoleate aerial parts 0.6
Inula viscosa methylhexadecanoate aerial parts 1.1
Inula viscosa modheph-2-ene aerial parts 0.2
Inula viscosa o-xylene aerial parts 0.6
Inula viscosa para-cymen-8-ol aerial parts 0.4
Inula viscosa para-mentha-1(7),2-dien-8-ol aerial parts 0.4
Inula viscosa para-xylene aerial parts 0.4
Inula viscosa pentacosane aerial parts 0.9
Inula viscosa phytol aerial parts 1.3
Inula viscosa phytone aerial parts 5
Inula viscosa selin-11-en-4-alpha-ol aerial parts 3.3
Inula viscosa selin-6-en-4-alpha-ol aerial parts 1.5
Inula viscosa tetradecanoic acid aerial parts 1.2
Inula viscosa tricosane aerial parts 0.2