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Title chemical composition, antioxidant/antibacterial activities and admet study of the essential oil isolated from the aerial parts of ziziphora hispanica grown in morocco
Journal journal of essential oil research
Year 2023
DOI 10.1080/10412905.2023.2170483
Cited By 6
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Abstract
the present study aimed to characterize the chemical composition and evaluate the antioxidant and antibacterial activities along with the absorption, distribution, metabolism, excretion, toxicity (admet) study of the essential oil of ziziphora hispanica (zh-eo), collected from the middle atlas of morocco (boulmane). results showed that a total of 119 volatile components, characterized by gc-fid and gc-ms analysis, which represents the 88.7% of the total of zh-eo. zh-eo displayed a bactericidal effect against listeria monocytogenes, pseudomonas aeruginosa and enterococcus faecalis, and a bacteriostatic effect against staphylococcus aureus. furthermore, zh-eo exhibited strong antioxidant activity against dpph radical (ic50 = 1.3 mg/ml). the admet prediction showed good pharmacokinetic properties of the tested components. the findings obtained from this study suggest that ziziphora hispanica essential oil could represent a source of bioactive molecules with antioxidant and antibacterial potential in the prevention against diseases related to oxidative stress and pathogenic bacteria.
1
Plants
43
Compounds
43
Records

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Compounds
Plants
Plant Parts
All Records
CompoundCount
alpha-bisabolol1
isoisopulegol1
germacrene d1
germacra-4 (15), 5,10 (14)-trien-1-alpha-ol1
geranyl acetate1
eugenol1
caryophyllene oxide1
beta-elemene1
beta-bourbonene1
alpha-terpineol1
alpha-copaene1
isomenthone1
7a-hydroxymintlactone1
4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthol1
2-methylcyclopentanone1
1-methyl-4-(1-methylethenyl)-1,2-cyclohexanediol1
(z)-para-mentha-2,8-dien-1-ol1
(z)-limonene oxide1
(e,e)-3,5-octadien-2-one1
(e)-sabinene hydrate1
(e)-caryophyllene1
(e)-anethole1
n-hexadecanoic acid1
thymol1
pulegone1
piperitenone1
phytone1
phytol1
para-menth-3-en-8-ol1
o-acetanisole1
n-octadecane1
n-nonanal1
n-nonadecane1
verbenone1
n-heneicosane1
neryl acetate1
myrtenal1
menthofurolactone1
menthofuran1
linalool1
limonene1
isopulegone1
isopentyl alcohol1
PlantFamily
Ziziphora hispanicalamiaceae
Plant PartCount
aerial parts43
PlantCompoundPart%
Ziziphora hispanica (e,e)-3,5-octadien-2-one aerial parts 0.1
Ziziphora hispanica (e)-anethole aerial parts 2
Ziziphora hispanica (e)-caryophyllene aerial parts 0.7
Ziziphora hispanica (e)-sabinene hydrate aerial parts 0.1
Ziziphora hispanica (z)-limonene oxide aerial parts 0.1
Ziziphora hispanica (z)-para-mentha-2,8-dien-1-ol aerial parts 0.3
Ziziphora hispanica 1-methyl-4-(1-methylethenyl)-1,2-cyclohexanediol aerial parts 0.1
Ziziphora hispanica 2-methylcyclopentanone aerial parts 2.8
Ziziphora hispanica 4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthol aerial parts 0.2
Ziziphora hispanica 7a-hydroxymintlactone aerial parts 1.1
Ziziphora hispanica alpha-bisabolol aerial parts 0.1
Ziziphora hispanica alpha-copaene aerial parts 0.1
Ziziphora hispanica alpha-terpineol aerial parts 0.5
Ziziphora hispanica beta-bourbonene aerial parts 0.1
Ziziphora hispanica beta-elemene aerial parts 0.1
Ziziphora hispanica caryophyllene oxide aerial parts 0.5
Ziziphora hispanica eugenol aerial parts 0.2
Ziziphora hispanica geranyl acetate aerial parts 0.1
Ziziphora hispanica germacra-4 (15), 5,10 (14)-trien-1-alpha-ol aerial parts 0.1
Ziziphora hispanica germacrene d aerial parts 0.1
Ziziphora hispanica isoisopulegol aerial parts 0.2
Ziziphora hispanica isomenthone aerial parts 0.3
Ziziphora hispanica isopentyl alcohol aerial parts 0.1
Ziziphora hispanica isopulegone aerial parts 0.5
Ziziphora hispanica limonene aerial parts 0.6
Ziziphora hispanica linalool aerial parts 0.1
Ziziphora hispanica menthofuran aerial parts 2.6
Ziziphora hispanica menthofurolactone aerial parts 0.3
Ziziphora hispanica myrtenal aerial parts 0.1
Ziziphora hispanica n-heneicosane aerial parts 0.1
Ziziphora hispanica n-hexadecanoic acid aerial parts 0.4
Ziziphora hispanica n-nonadecane aerial parts 0.1
Ziziphora hispanica n-nonanal aerial parts 0.3
Ziziphora hispanica n-octadecane aerial parts 0.5
Ziziphora hispanica neryl acetate aerial parts 0.1
Ziziphora hispanica o-acetanisole aerial parts 0.1
Ziziphora hispanica para-menth-3-en-8-ol aerial parts 1.2
Ziziphora hispanica phytol aerial parts 0.3
Ziziphora hispanica phytone aerial parts 0.2
Ziziphora hispanica piperitenone aerial parts 0.5
Ziziphora hispanica pulegone aerial parts 72.7
Ziziphora hispanica thymol aerial parts 0.1
Ziziphora hispanica verbenone aerial parts 0.4