bioactive compounds are the frontline potent agents in both nutraceutical and pharmaceutical industries.recently, the bioactive compounds are gaining much importance for their ability in enhancing resistance to various diseases and to improve the health of people both by traditional and modern ways of administrations.therefore, in the present investigation was undertaken to identify the compounds present in the leaf of waltheria indica linn.by gas chromatography-mass spectrometry (gc-ms) analysis by ethanol extract.the gc-ms analysis showed 27 bioactive compounds.the major compounds identified are 2,3-dihydro-3,5-dihydroxy-6-methyl-4h-pyran-4-one, tetradecane, nonadecane, tetracosane, phytol and squalene.in a mass spectrum, each compounds were identified based on their retention time and peak area.pharmacological activities of these compounds indicated that the compounds present in the leaf of said plant can be used as a crude drug and can also be used to develop a novel drug.