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Title phytochemical compositions and antidiabetic potentials of <i>salvia sclarea</i> l. essential oils
Journal journal of oleo science
Year 2018
DOI 10.5650/jos.ess17187
Cited By 38
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Abstract
salvia sclarea (ss) is characterized by its valuable essential oils (eos) and potent biological activities. this study aimed at investigating the phytochemical composition of ss eos collected in within the same week, from two different regions in lebanon, beirut (ss-bt) and taanayel (ss-tl), utilizing gc-ms methods, and to explore their acute and subchronic antidiabetic potentials. moreover, studying the phytochemical diversity of twenty ss eos established on our work and literature descriptions in order to recognize the origin of the lebanese active chemotype(s). the eos have been obtained by hydro-distillation and identified via gc-ms analyses. five chemotypes of ss eos have been identified. the lebanese eos, ss-bt and ss-tl, studied here have shown evidence to belong to two different chemotypes 1 and 5, respectively. ss-bt has shown to belong to chemotype 1, which is characterized by high linalool (ll) concentration (average 40.2%). on the other hand, ss-tl has shown to belong to chemotype 5, which is characterized by high linalyl acetate (la) concentration (average 50.4%). the acute and subchronic antidiabetic activities of these eos have been monitored along with ll and la, in order to find the most active chemotype. chemotypes 1 (owned to high ll content), present at low altitude places of lebanon and poland, has shown significantly higher acute and subchronic antidiabetic activities than that of chemotype 5 (owned to high la content). in conclusion, salvia sclarea eos have shown potential antidiabetic activities, and their eos might be used in the future as a complementary or an alternative medicine in the management of diabetes and related complications.
1
Plants
66
Compounds
132
Records

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Compounds
Plants
Plant Parts
All Records
CompoundCount
alpha-calacorene2
cedrol2
torilenol2
humulene epoxide2
salvial-4(14)en-1-one2
caryophyllene oxide2
spathulenol2
beta-calacorene2
salviadienol2
12-epi-cedrol2
delta-cadinene2
cubebol2
bicyclogermacrene2
beta-selinene2
germacrene d2
beta-ionone2
(e,e)-alpha-farnesene2
isogermacrene2
humulene epoxide iii2
tau-cadinol2
beta-eudesmol2
alpha-eudesmol2
eudesma-4(15),7-dien-1beta-ol2
alpha-bisabolol2
(z,z)-farnesol2
(e,e)-farnesol2
(e)-2,6-dimethyl-10-(para-tolyl)-undeca-2,6-diene2
manoyl oxide2
13-epi-manoyl oxide2
manool2
13-epi-manool2
labda-7,14-dien-13-ol2
sclareol2
(z)-beta-ocimene2
borneol2
pinocamphone2
endo-fenchol2
linalool2
terpinolene2
fenchone2
gamma-terpinene2
(e)-beta-ocimene2
terpinen-4-ol2
limonene2
para-cymene2
alpha-terpinene2
alpha-phellandrene2
myrcene2
camphene2
beta-pinene2
alpha-pinene2
alpha-terpineol2
nerol2
pulegone2
geraniol2
linalyl acetate2
neryl formate2
bicycloelemene2
neryl acetate2
alpha-cubebene2
geranyl acetate2
alpha-copaene2
beta-bourbonene2
beta-elemene2
alpha-cedrene2
beta-caryophyllene2
PlantFamily
Salvia sclarealamiaceae
Plant PartCount
aerial parts132
PlantCompoundPart%
Salvia sclarea (e,e)-alpha-farnesene aerial parts 0.005
Salvia sclarea (e,e)-alpha-farnesene aerial parts 0.27
Salvia sclarea (e,e)-farnesol aerial parts 0.1
Salvia sclarea (e,e)-farnesol aerial parts 0.005
Salvia sclarea (e)-2,6-dimethyl-10-(para-tolyl)-undeca-2,6-diene aerial parts 0.18
Salvia sclarea (e)-2,6-dimethyl-10-(para-tolyl)-undeca-2,6-diene aerial parts 0.3
Salvia sclarea (e)-beta-ocimene aerial parts 0.18
Salvia sclarea (e)-beta-ocimene aerial parts 1.9
Salvia sclarea (z,z)-farnesol aerial parts 0.2
Salvia sclarea (z,z)-farnesol aerial parts 0.1
Salvia sclarea (z)-beta-ocimene aerial parts 0.09
Salvia sclarea (z)-beta-ocimene aerial parts 0.09
Salvia sclarea 12-epi-cedrol aerial parts 0.18
Salvia sclarea 12-epi-cedrol aerial parts 0.005
Salvia sclarea 13-epi-manool aerial parts 0.18
Salvia sclarea 13-epi-manool aerial parts 0.005
Salvia sclarea 13-epi-manoyl oxide aerial parts 0.1
Salvia sclarea 13-epi-manoyl oxide aerial parts 0.18
Salvia sclarea alpha-bisabolol aerial parts 0.09
Salvia sclarea alpha-bisabolol aerial parts 0.005
Salvia sclarea alpha-calacorene aerial parts 0.005
Salvia sclarea alpha-calacorene aerial parts 0.18
Salvia sclarea alpha-cedrene aerial parts 0.1
Salvia sclarea alpha-cedrene aerial parts 0.005
Salvia sclarea alpha-copaene aerial parts 0.9
Salvia sclarea alpha-copaene aerial parts 1.1
Salvia sclarea alpha-cubebene aerial parts 0.1
Salvia sclarea alpha-cubebene aerial parts 0.1
Salvia sclarea alpha-eudesmol aerial parts 0.27
Salvia sclarea alpha-eudesmol aerial parts 0.27
Salvia sclarea alpha-phellandrene aerial parts 0.09
Salvia sclarea alpha-phellandrene aerial parts 0.09
Salvia sclarea alpha-pinene aerial parts 0.09
Salvia sclarea alpha-pinene aerial parts 0.005
Salvia sclarea alpha-terpinene aerial parts 0.09
Salvia sclarea alpha-terpinene aerial parts 0.005
Salvia sclarea alpha-terpineol aerial parts 6.45
Salvia sclarea alpha-terpineol aerial parts 13.4
Salvia sclarea beta-bourbonene aerial parts 0.18
Salvia sclarea beta-bourbonene aerial parts 0.005
Salvia sclarea beta-calacorene aerial parts 0.1
Salvia sclarea beta-calacorene aerial parts 0.005
Salvia sclarea beta-caryophyllene aerial parts 1
Salvia sclarea beta-caryophyllene aerial parts 2.26
Salvia sclarea beta-elemene aerial parts 0.27
Salvia sclarea beta-elemene aerial parts 0.005
Salvia sclarea beta-eudesmol aerial parts 0.45
Salvia sclarea beta-eudesmol aerial parts 0.45
Salvia sclarea beta-ionone aerial parts 0.005
Salvia sclarea beta-ionone aerial parts 0.18
Salvia sclarea beta-pinene aerial parts 0.09
Salvia sclarea beta-pinene aerial parts 0.09
Salvia sclarea beta-selinene aerial parts 0.005
Salvia sclarea beta-selinene aerial parts 0.18
Salvia sclarea bicycloelemene aerial parts 0.005
Salvia sclarea bicycloelemene aerial parts 0.18
Salvia sclarea bicyclogermacrene aerial parts 1.18
Salvia sclarea bicyclogermacrene aerial parts 0.27
Salvia sclarea borneol aerial parts 0.1
Salvia sclarea borneol aerial parts 0.1
Salvia sclarea camphene aerial parts 0.09
Salvia sclarea camphene aerial parts 0.005
Salvia sclarea caryophyllene oxide aerial parts 1.34
Salvia sclarea caryophyllene oxide aerial parts 0.5
Salvia sclarea cedrol aerial parts 0.005
Salvia sclarea cedrol aerial parts 0.18
Salvia sclarea cubebol aerial parts 0.005
Salvia sclarea cubebol aerial parts 0.1
Salvia sclarea delta-cadinene aerial parts 0.36
Salvia sclarea delta-cadinene aerial parts 0.27
Salvia sclarea endo-fenchol aerial parts 0.005
Salvia sclarea endo-fenchol aerial parts 0.18
Salvia sclarea eudesma-4(15),7-dien-1beta-ol aerial parts 0.005
Salvia sclarea eudesma-4(15),7-dien-1beta-ol aerial parts 0.27
Salvia sclarea fenchone aerial parts 0.09
Salvia sclarea fenchone aerial parts 0.005
Salvia sclarea gamma-terpinene aerial parts 0.18
Salvia sclarea gamma-terpinene aerial parts 0.27
Salvia sclarea geraniol aerial parts 5.67
Salvia sclarea geraniol aerial parts 4.4
Salvia sclarea geranyl acetate aerial parts 3.45
Salvia sclarea geranyl acetate aerial parts 4.86
Salvia sclarea germacrene d aerial parts 2
Salvia sclarea germacrene d aerial parts 10.6
Salvia sclarea humulene epoxide aerial parts 0.1
Salvia sclarea humulene epoxide aerial parts 0.1
Salvia sclarea humulene epoxide iii aerial parts 0.18
Salvia sclarea humulene epoxide iii aerial parts 0.1
Salvia sclarea isogermacrene aerial parts 0.1
Salvia sclarea isogermacrene aerial parts 0.005
Salvia sclarea labda-7,14-dien-13-ol aerial parts 0.005
Salvia sclarea labda-7,14-dien-13-ol aerial parts 0.1
Salvia sclarea limonene aerial parts 0.18
Salvia sclarea limonene aerial parts 0.08
Salvia sclarea linalool aerial parts 38.07
Salvia sclarea linalool aerial parts 10.75
Salvia sclarea linalyl acetate aerial parts 1
Salvia sclarea linalyl acetate aerial parts 35.28
Salvia sclarea manool aerial parts 0.18
Salvia sclarea manool aerial parts 0.1
Salvia sclarea manoyl oxide aerial parts 0.1
Salvia sclarea manoyl oxide aerial parts 0.36
Salvia sclarea myrcene aerial parts 3
Salvia sclarea myrcene aerial parts 0.63
Salvia sclarea nerol aerial parts 2.07
Salvia sclarea nerol aerial parts 1
Salvia sclarea neryl acetate aerial parts 2.52
Salvia sclarea neryl acetate aerial parts 1.8
Salvia sclarea neryl formate aerial parts 0.1
Salvia sclarea neryl formate aerial parts 0.005
Salvia sclarea para-cymene aerial parts 0.09
Salvia sclarea para-cymene aerial parts 0.45
Salvia sclarea pinocamphone aerial parts 0.1
Salvia sclarea pinocamphone aerial parts 0.005
Salvia sclarea pulegone aerial parts 0.005
Salvia sclarea pulegone aerial parts 0.36
Salvia sclarea salviadienol aerial parts 0.005
Salvia sclarea salviadienol aerial parts 0.1
Salvia sclarea salvial-4(14)en-1-one aerial parts 0.005
Salvia sclarea salvial-4(14)en-1-one aerial parts 0.36
Salvia sclarea sclareol aerial parts 0.1
Salvia sclarea sclareol aerial parts 1.18
Salvia sclarea spathulenol aerial parts 0.18
Salvia sclarea spathulenol aerial parts 1.45
Salvia sclarea tau-cadinol aerial parts 0.005
Salvia sclarea tau-cadinol aerial parts 0.18
Salvia sclarea terpinen-4-ol aerial parts 0.1
Salvia sclarea terpinen-4-ol aerial parts 0.2
Salvia sclarea terpinolene aerial parts 0.05
Salvia sclarea terpinolene aerial parts 0.005
Salvia sclarea torilenol aerial parts 0.005
Salvia sclarea torilenol aerial parts 0.1