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Plant Genus: carica
Plant Name Plant Family Compound Name Compound Activity Chemical Group Plant Part Percentage Details(ID)
Carica papaya caricaceae phenylacetaldehydeb NA fruit 0.04 101256
Carica papaya caricaceae myristic acid 2679 wax monoesters fruit 0.38 101265
Carica papaya caricaceae methyl-4-oxooctanaoate wax monoesters fruit 0.01 101268
Carica papaya caricaceae methyl pyrazine pyrazine and piperazine alkaloids fruit 0.005 101274
Carica papaya caricaceae methyl linoleate wax monoesters fruit 0.03 101282
Carica papaya caricaceae methyl hexanoate wax monoesters fruit 0.3 101283
Carica papaya caricaceae methyl furoate NA fruit 0.01 101284
Carica papaya caricaceae methyl acetylbutanoate wax monoesters fruit 0.01 101289
Carica papaya caricaceae methyl (e)-2-hexenoate wax monoesters fruit 0.02 101299
Carica papaya caricaceae geranyl linalool acyclic monoterpenoids fruit 0.11 101311
Carica papaya caricaceae geranyl acetone apocarotenoids (-) fruit 0.02 101312
Carica papaya caricaceae gamma-octalactone lactones fruit 0.01 101314
Carica papaya caricaceae gamma-nonalactone lactones fruit 0.01 101315
Carica papaya caricaceae ethyl palmitate wax monoesters fruit 0.09 101327
Carica papaya caricaceae ethyl formate wax monoesters fruit 0.01 101338
Carica papaya caricaceae dimethyl disulfide NA fruit 0.05 101349
Carica papaya caricaceae (e)-linalool oxide (pyranoid) acyclic monoterpenoids fruit 0.005 101408
Carica papaya caricaceae (e)-linalool oxide acyclic monoterpenoids fruit 0.13 101409
Carica papaya caricaceae (e)-beta-ionone apocarotenoids (-) fruit 0.005 101410
Carica papaya caricaceae alpha-humulene anti--inflammatory, anti-cancer, analgesic, anti-microbial humulane sesquiterpenoids fruit 0.005 101360
Carica papaya caricaceae 1,8-cineole anti--inflammatory, anti-microbial, mucolytic, bronchodilator, anti-oxidant menthane monoterpenoids fruit 0.005 101395
Carica papaya caricaceae pentadecanoic acid anti--inflammatory, anti-microbial; biomarker of dairy fat intake, cardiometabolic protection, reduced inflammation, enhanced cellular longevity branched fatty acids fruit 0.3 101258
Carica papaya caricaceae ethyl-(z)-9-palmitoleate anti--inflammatory, anti-oxidant, anti-bacterial, hypolipidemic wax monoesters fruit 0.07 101324
Carica papaya caricaceae limonene anti--inflammatory, anti-oxidant, anti-cancer,anti-microbial menthane monoterpenoids fruit 0.37 101303
Carica papaya caricaceae alpha-pinene anti--inflammatory, anti-oxidant, anti-microbial, and acetylcholinesterase inhibitor pinane monoterpenoids fruit 0.01 101359
Carica papaya caricaceae ethyl oleate anti--inflammatory, anti-oxidant, anti-microbial, drug delivery agent, hypolipidemic wax monoesters fruit 0.15 101328
Carica papaya caricaceae methyl palmitoleate anti--inflammatory, anti-oxidant, anti-microbial, hypolipidemic wax monoesters fruit 0.08 101277
Carica papaya caricaceae ethyl (e)-9-palmitoleate anti--inflammatory, anti-oxidant, anti-microbial, hypolipidemic NA fruit 0.06 101344
Carica papaya caricaceae ethyl linoleate anti--inflammatory, anti-oxidant, anti-microbial, wound healing wax monoesters fruit 0.13 101333
Carica papaya caricaceae (e)-palmitoleic acid anti--inflammatory, anti-oxidant, cardioprotective, anti-diabetic unsaturated fatty acids fruit 0.31 101407
Carica papaya caricaceae ethyl linolenate anti--inflammatory, anti-oxidant, cardioprotective, anti-microbial, neuroprotective wax monoesters fruit 0.14 101332
Carica papaya caricaceae 2-butanol anti-bacterial (limited evidence) fatty alcohols fruit 0.01 101383
Carica papaya caricaceae isobutanol anti-bacterial (limited evidence), anti-fungal, solvent fatty alcohols fruit 0.12 101306
Carica papaya caricaceae isopentanal anti-bacterial (limited evidence), flavor compound fatty aldehydes fruit 0.02 101305
Carica papaya caricaceae ethylbutanoate anti-bacterial (limited evidence), flavor compound wax monoesters fruit 0.8 101319
Carica papaya caricaceae ethyl heptanoate anti-bacterial (limited evidence), flavor compound wax monoesters fruit 0.005 101337
Carica papaya caricaceae 2,3-pentanedione anti-bacterial (limited evidence), flavor compound oxygenated hydrocarbons fruit 0.01 101387
Carica papaya caricaceae 3-penten-2-one anti-bacterial (limited evidence), flavor volatile oxygenated hydrocarbons fruit 0.03 101370
Carica papaya caricaceae 2-pentanone anti-bacterial (limited evidence), flavor volatile oxygenated hydrocarbons fruit 0.02 101376
Carica papaya caricaceae 1-penten-3-one anti-bacterial (limited evidence), plant volatile oxygenated hydrocarbons fruit 0.01 101389
Carica papaya caricaceae 1-hexen-3-one anti-bacterial (limited evidence), plant volatile oxygenated hydrocarbons fruit 0.03 101392
Carica papaya caricaceae heptadecanoic acid anti-bacterial, anti--inflammatory, anti-oxidant branched fatty acids fruit 0.005 101310
Carica papaya caricaceae (z)-palmitoleic acid anti-bacterial, anti--inflammatory, anti-oxidant, anti-diabetic, cardioprotective, wound healing unsaturated fatty acids fruit 0.34 101396
Carica papaya caricaceae octadecanoic acid anti-bacterial, anti--inflammatory, emollient unsaturated fatty acids fruit 0.005 101263
Carica papaya caricaceae methyl (e)-2-octenoate anti-bacterial, anti-fungal (limited evidence) wax monoesters fruit 0.07 101298
Carica papaya caricaceae ethylbenzoate anti-bacterial, anti-fungal (limited evidence) simple phenolic acids fruit 0.06 101320
Carica papaya caricaceae 2-tridecanol anti-bacterial, anti-fungal (limited evidence) fatty alcohols fruit 0.01 101374
Carica papaya caricaceae 2-pentanol anti-bacterial, anti-fungal (limited evidence) fatty alcohols fruit 0.01 101377
Carica papaya caricaceae 2-methylbutanol anti-bacterial, anti-fungal (limited evidence) fatty alcohols fruit 0.05 101381
Carica papaya caricaceae 1-penten-3-ol anti-bacterial, anti-fungal (limited evidence) fatty alcohols fruit 0.04 101390
Carica papaya caricaceae 1-butanol anti-bacterial, anti-fungal (limited evidence) fatty alcohols fruit 0.42 101394
Carica papaya caricaceae (z)-2-pentenol anti-bacterial, anti-fungal (limited evidence) fatty alcohols fruit 0.04 101404
Carica papaya caricaceae gamma-hexalactone anti-bacterial, anti-fungal (limited evidence), flavor compound lactones fruit 0.02 101316
Carica papaya caricaceae ethyl hexanoate anti-bacterial, anti-fungal (limited evidence), flavor compound wax monoesters fruit 0.01 101336
Carica papaya caricaceae ethyl (e)-2-octenoate anti-bacterial, anti-fungal (limited evidence), flavor compound wax monoesters fruit 0.005 101345
Carica papaya caricaceae ethyl (e)-2-hexenoate anti-bacterial, anti-fungal (limited evidence), flavor compound wax monoesters fruit 0.01 101346
Carica papaya caricaceae diacetyl anti-bacterial, anti-fungal (limited evidence), food flavoring compound oxygenated hydrocarbons fruit 0.1 101350
Carica papaya caricaceae (z)-3-hexenyl butanoate anti-bacterial, anti-fungal (limited evidence), plant defense volatile wax monoesters fruit 0.005 101400
Carica papaya caricaceae (e)-2-pentenol anti-bacterial, anti-fungal (limited evidence), plant volatile fatty alcohols fruit 0.09 101413
Carica papaya caricaceae tridecanoic acid anti-bacterial, anti-fungal, anti--inflammatory branched fatty acids fruit 0.02 101250
Carica papaya caricaceae methyl myristate anti-bacterial, anti-fungal, anti--inflammatory wax monoesters fruit 0.05 101279
Carica papaya caricaceae methyl dodecanoate anti-bacterial, anti-fungal, anti--inflammatory wax monoesters fruit 0.01 101285
Carica papaya caricaceae ethyl myristate anti-bacterial, anti-fungal, anti--inflammatory (limited evidence) wax monoesters fruit 0.2 101330
Carica papaya caricaceae ethyl dodecanoate anti-bacterial, anti-fungal, anti--inflammatory (limited evidence) wax monoesters fruit 0.07 101339
Carica papaya caricaceae methyl (z)-9-oleate anti-bacterial, anti-fungal, anti--inflammatory, anti-oxidant wax monoesters fruit 0.03 101296
Carica papaya caricaceae (e,e)-farnesol anti-bacterial, anti-fungal, anti-biofilm, anti-oxidant, anti--inflammatory, anti-cancer, pro-apoptotic acyclic monoterpenoids fruit 0.02 101406
Carica papaya caricaceae benzyl isothiocyanate anti-bacterial, anti-fungal, anti-cancer, anti--inflammatory, anti-oxidant, chemopreventive NA fruit 0.2 101354
Carica papaya caricaceae benzyl alcohol anti-bacterial, anti-fungal, anti-microbial preservative, local anesthetic NA fruit 0.07 101356
Carica papaya caricaceae propanoic acid anti-bacterial, anti-fungal, anti-microbial, food preservative branched fatty acids fruit 0.005 101255
Carica papaya caricaceae methyl octanoate anti-bacterial, anti-fungal, anti-oxidant wax monoesters fruit 0.005 101278
Carica papaya caricaceae methyl decanoate anti-bacterial, anti-fungal, anti-oxidant wax monoesters fruit 0.01 101286
Carica papaya caricaceae furfuryl alcohol anti-bacterial, anti-fungal, anti-oxidant (limited evidence) furans fruit 0.005 101317
Carica papaya caricaceae ethyl decanoate anti-bacterial, anti-fungal, anti-oxidant (limited evidence) wax monoesters fruit 0.07 101340
Carica papaya caricaceae ethyl octanoate anti-bacterial, anti-fungal, anti-oxidant (limited evidence), flavor compound wax monoesters fruit 0.05 101329
Carica papaya caricaceae furfural anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory furans fruit 0.1 101318
Carica papaya caricaceae 4-vinylguaiacol anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory cinnamic acids and derivatives fruit 0.06 101369
Carica papaya caricaceae (z)-linalool oxide (pyranoid) anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory acyclic monoterpenoids fruit 0.05 101397
Carica papaya caricaceae (z)-linalool oxide anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory acyclic monoterpenoids fruit 0.01 101398
Carica papaya caricaceae 2-phenylethanol anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory, anti-biofilm phenylethanoids fruit 0.03 101375
Carica papaya caricaceae (z)-carveol anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory, anti-nociceptive menthane monoterpenoids fruit 0.005 101399
Carica papaya caricaceae (e)-2-hexenal anti-bacterial, anti-fungal, anti-oxidant, anti--inflammatory, insecticidal, plant defense signaling fatty aldehydes fruit 0.01 101415
Carica papaya caricaceae 1-hexanol anti-bacterial, anti-fungal, anti-oxidant, insecticidal fatty alcohols fruit 0.05 101393
Carica papaya caricaceae (z)-2-hexenol anti-bacterial, anti-fungal, anti-oxidant, plant defense signaling fatty alcohols fruit 0.02 101405
Carica papaya caricaceae (e)-2-hexenol anti-bacterial, anti-fungal, anti-oxidant, plant defense signaling fatty alcohols fruit 0.05 101414
Carica papaya caricaceae (z)-3-hexenol anti-bacterial, anti-fungal, anti-oxidant, plant defense signaling, insect attractant/repellent fatty alcohols fruit 0.04 101402
Carica papaya caricaceae octanoic acid anti-bacterial, anti-fungal, anti-viral, anti--inflammatory branched fatty acids fruit 0.06 101262
Carica papaya caricaceae decanoic acid anti-bacterial, anti-fungal, anti-viral, anti--inflammatory, anti-oxidant branched fatty acids fruit 0.3 101351
Carica papaya caricaceae dodecanoic acid anti-bacterial, anti-fungal, anti-viral, anti--inflammatory, anti-oxidant, anti-biofilm branched fatty acids fruit 0.37 101348
Carica papaya caricaceae acetic acid anti-bacterial, anti-fungal, anti-viral, anti-biofilm, anti--inflammatory (topical) aminoacids fruit 0.005 101365
Carica papaya caricaceae isopropanol anti-bacterial, anti-fungal, anti-viral, disinfectant fatty alcohols fruit 0.06 101304
Carica papaya caricaceae 1-propanol anti-bacterial, anti-fungal, disinfectant fatty alcohols fruit 0.12 101388
Carica papaya caricaceae 3-methyl-1-butanol anti-bacterial, anti-fungal, insect attractant, plant volatile fatty alcohols fruit 0.83 101371
Carica papaya caricaceae 6-methyl-5-hepten-2-one anti-bacterial, anti-fungal, insect attractant/repellent, mosquito semiochemical acyclic monoterpenoids fruit 0.01 101367
Carica papaya caricaceae 2-octanone anti-bacterial, anti-fungal, insect repellent, nematicidal oxygenated hydrocarbons fruit 0.005 101379
Carica papaya caricaceae 2-pentadecanone anti-bacterial, anti-fungal, insecticidal oxygenated hydrocarbons fruit 0.02 101378
Carica papaya caricaceae 1-octanol anti-bacterial, anti-fungal, insecticidal, insect repellent fatty alcohols fruit 0.005 101391
Carica papaya caricaceae ethyl pentadecanoate anti-bacterial, anti-oxidant (limited evidence) wax monoesters fruit 0.01 101326
Carica papaya caricaceae carvone anti-bacterial; anti-fungal; anti-oxidant; anti--inflammatory; anti-cancer; insecticidal; anti-spasmodic menthane monoterpenoids fruit 0.01 101352
Carica papaya caricaceae thiobenzoic acid anti-microbial (limited evidence) NA fruit 0.005 101252
Carica papaya caricaceae methyl methyl thiocyanate anti-microbial (limited evidence) NA fruit 0.005 101281
Carica papaya caricaceae methyl 2-hydroxy-3-methylpentanoate anti-microbial (limited evidence) wax monoesters fruit 0.005 101294
Carica papaya caricaceae methyl 2-hydroxy-2-methylbutanoate anti-microbial (limited evidence) hydroxy fatty acids fruit 0.01 101295
Carica papaya caricaceae ethyl 2-hydroxyhexanoate anti-microbial (limited evidence) wax monoesters fruit 0.01 101343
Carica papaya caricaceae benzyl crotonate anti-microbial (limited evidence) cinnamic acids and derivatives fruit 0.02 101355
Carica papaya caricaceae 5-methyl-2-hexanone anti-microbial (limited evidence) oxygenated hydrocarbons fruit 0.005 101368
Carica papaya caricaceae 3,5,5-trimethyl-2-cyclohexanone anti-microbial (limited evidence) apocarotenoids(-) fruit 0.08 101372
Carica papaya caricaceae 2-methylthioethanol anti-microbial (limited evidence) fatty alcohols fruit 0.03 101380
Carica papaya caricaceae ethyl 3-hydroxyhexanoate anti-microbial (limited evidence), anti-oxidant (reported in fermentation/food studies) wax monoesters fruit 0.005 101342
Carica papaya caricaceae ethyl lactate anti-microbial (limited evidence), biodegradable solvent, pharmaceutical excipient wax monoesters fruit 0.02 101334
Carica papaya caricaceae methyl 2-methylbutanoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.005 101290
Carica papaya caricaceae methyl (z)-2-butenoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.005 101297
Carica papaya caricaceae methyl (e)-2-butenoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.12 101300
Carica papaya caricaceae isoamyl hexanoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.05 101307
Carica papaya caricaceae isoamyl butanoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.01 101308
Carica papaya caricaceae ethyl propanoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.005 101325
Carica papaya caricaceae ethyl methylthioacetate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.005 101331
Carica papaya caricaceae ethyl isopentanoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.005 101335
Carica papaya caricaceae ethyl (e)-2-butenoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.01 101347
Carica papaya caricaceae butanal anti-microbial (limited evidence), flavor compound fatty aldehydes fruit 0.005 101353
Carica papaya caricaceae allyl octanoate anti-microbial (limited evidence), flavor compound wax monoesters fruit 0.005 101361
Carica papaya caricaceae methyl 2-hydroxyisopentanoate anti-microbial (limited evidence), microbial metabolite hydroxy fatty acids fruit 0.005 101291
Carica papaya caricaceae methyl 2-hydroxybutanoate anti-microbial (limited evidence), microbial metabolite hydroxy fatty acids fruit 0.2 101292
Carica papaya caricaceae methyl 2-hydroxy-4-methyl pentanoate anti-microbial (limited evidence), microbial metabolite NA fruit 0.11 101293
Carica papaya caricaceae ethyl-3-hydroxybutanoate anti-microbial (limited evidence), microbial metabolite wax monoesters fruit 0.04 101323
Carica papaya caricaceae ethyl 5-hydroxyhexanoate anti-microbial (limited evidence), microbial metabolite wax monoesters fruit 0.005 101341
Carica papaya caricaceae ethylacetate anti-microbial (limited evidence), solvent, flavor compound wax monoesters fruit 0.005 101322
Carica papaya caricaceae methyl propyl sulphide anti-microbial (limited evidence); flavor compound fatty alcohols fruit 0.005 101275
Carica papaya caricaceae methyl methylthioacetate anti-microbial (limited evidence); flavor compound wax monoesters fruit 0.02 101280
Carica papaya caricaceae methyl propanoate anti-microbial (limited evidence); flavoring agent wax monoesters fruit 0.14 101276
Carica papaya caricaceae methyl butanoate anti-microbial (limited evidence); flavoring agent wax monoesters fruit 2.3 101287
Carica papaya caricaceae phenyl acetonitrile anti-microbial (limited), insect semiochemical, plant defense compound NA fruit 0.05 101257
Carica papaya caricaceae methyl-3-hydroxy butanoate anti-microbial (limited), microbial metabolite hydroxy fatty acids fruit 0.05 101272
Carica papaya caricaceae terpinen-4-ol anti-microbial, anti--inflammatory, and anti--cancer menthane monoterpenoids fruit 0.005 101253
Carica papaya caricaceae alpha-terpineol anti-microbial, anti--inflammatory, anti-cancer, anti-oxidant menthane monoterpenoids fruit 0.01 101358
Carica papaya caricaceae palmitic acid anti-microbial, anti--inflammatory, cytotoxic, pro-inflammatory branched fatty acids fruit 0.36 101261
Carica papaya caricaceae nonanal anti-microbial, anti-fungal fatty aldehydes fruit 0.07 101264
Carica papaya caricaceae hexanal anti-microbial, anti-fungal fatty aldehydes fruit 0.005 101309
Carica papaya caricaceae benzaldehyde anti-microbial, anti-fungal, and insecticidal agent, alongside potential anti-tumor properties NA fruit 0.03 101357
Carica papaya caricaceae linalool anti-microbial, anti-oxidant, anti--inflammatory acyclic monoterpenoids fruit 0.08 101302
Carica papaya caricaceae methyl benzoate anti-microbial, anti-oxidant, insect attractant simple phenolic acids fruit 0.07 101288
Carica papaya caricaceae methyl-3-methyl-2-butenoate anti-microbial, insect attractant/plant volatile (limited evidence) wax monoesters fruit 0.03 101269
Carica papaya caricaceae 2,6,6-trimethyl-2-cyclohexene-1,4-dione anti-oxidant, anti--inflammatory (limited evidence) apocarotenoids(-) fruit 0.01 101385
Carica papaya caricaceae para-cymene anti-oxidant, anti--inflammatory, anti-microbial, analgesic menthane monoterpenoids fruit 0.005 101260
Carica papaya caricaceae linolenic acid anti-oxidant, anti--inflammatory, anti-microbial, cardioprotective, neuroprotective, anti-cancer unsaturated fatty acids fruit 0.3 101301
Carica papaya caricaceae 2,6-dimethylpyrazine anti-oxidant, anti--inflammatory, neuroprotective, anti-microbial pyrazine and piperazine alkaloids fruit 0.005 101384
Carica papaya caricaceae 2,5-dimethylpyrazine anti-oxidant, anti--inflammatory, neuroprotective, anti-microbial pyrazine and piperazine alkaloids fruit 0.005 101386
Carica papaya caricaceae (e)-3-hexenol anti-oxidant, anti-microbial fatty alcohols fruit 0.005 101412
Carica papaya caricaceae gamma-terpinene anti-oxidant, anti-microbial & anti-fungal,anti--inflammatory and anti-nociceptive monocyclic monoterpenoids fruit 0.02 101313
Carica papaya caricaceae acetoin anti-oxidant, anti-microbial (limited), plant growth-promoting, anti--inflammatory oxygenated hydrocarbons fruit 0.18 101364
Carica papaya caricaceae (e)-beta-caryophyllene cb2 receptor agonist with strong anti--inflammatory, anti-oxidant, and analgesic properties caryophyllane sesquiterpenoids fruit 0.03 101411
Carica papaya caricaceae allyl cyclohexyl propanoate flavor compound; limited biological activity reported wax monoesters fruit 0.01 101362
Carica papaya caricaceae 2-tridecanone insecticidal, insect repellent, anti-bacterial, anti-fungal oxygenated hydrocarbons fruit 0.005 101373
Carica papaya caricaceae methyl-3-hydroxy pentanoate limited anti-microbial activity; microbial metabolite wax monoesters fruit 0.005 101270
Carica papaya caricaceae methyl-3-hydroxy hexanoate limited anti-microbial activity; microbial metabolite wax monoesters fruit 0.04 101271
Carica papaya caricaceae m-xylene no established pharmacological bioactivity; industrial solvent NA fruit 0.06 101267
Carica papaya caricaceae 2-butanone no established pharmacological bioactivity; industrial solvent oxygenated hydrocarbons fruit 0.005 101382
Carica papaya caricaceae acetone no established pharmacological bioactivity; industrial solvent; disinfectant (limited) oxygenated hydrocarbons fruit 0.04 101363
Carica papaya caricaceae para-xylene no established pharmacological bioactivity; industrial solvent; toxicological studies NA fruit 0.01 101259
Carica papaya caricaceae ethylbenzene no established pharmacological bioactivity; industrial solvent; toxicological studies NA fruit 0.01 101321
Carica papaya caricaceae pyridine no established pharmacological bioactivity; pharmaceutical intermediate pyridine alkaloids fruit 0.04 101254
Carica papaya caricaceae acetaldehyde no established pharmacological bioactivity; reactive metabolite, anti-microbial only at high concentrations fatty aldehydes fruit 0.08 101366
Carica papaya caricaceae (z)-2-propenal no established therapeutic bioactivity; highly reactive anti-microbial agent, toxic aldehyde NA fruit 0.005 101403
Carica papaya caricaceae toluene no established therapeutic bioactivity; industrial solvent; toxicological studies NA fruit 0.01 101251
Carica papaya caricaceae (z)-3-hexenyl acetate potent ecological and olfactory bioactivity , predator attraction wax monoesters fruit 0.005 101401
Carica papaya caricaceae myrcene sedative, analgesic, and anti--inflammatory acyclic monoterpenoids fruit 0.01 101266
Carica papaya caricaceae methyl salicylate topical analgesic, anti--inflammatory, counter-irritant simple phenolic acids fruit 0.01 101273